Objective: To investigate the effect and side effect of prepared Rehmannia polysaccharide (PRP) associated with stanozolol in treating chronic aplastic anemia (CAA). Methods:34 cases of CAA were treated by PRP liquid...Objective: To investigate the effect and side effect of prepared Rehmannia polysaccharide (PRP) associated with stanozolol in treating chronic aplastic anemia (CAA). Methods:34 cases of CAA were treated by PRP liquid associated with stanozolol for a course of 3 weeks treatment, and control group (17 cases of CAA) was treated by stanozolol alone. Results: Effective rate was 85. 3 % in treatment group, and that of control group was 58. 8 %,there was significant difference between them (P < 0. 05 ). Symptom remission of treatment group was earlier than that of control group.The difference of symptom scoring between two groups was significant (P < 0. 01 ). Blood cell had a distinct elevation after treatment with PRP associated with stanozolol, and had a significant difference in comparing with pretreatment in treatment group (P < 0. 01 ).Side effect of PRP was not found during treatment of CAA. Conclusion: PRP associated with stanozolol to treat CAA has an additional effect, it can accelerate symptom remission without any additional side effect.Original article on CJIM(Chin ) 1998; 18(6): 351展开更多
文摘Objective: To investigate the effect and side effect of prepared Rehmannia polysaccharide (PRP) associated with stanozolol in treating chronic aplastic anemia (CAA). Methods:34 cases of CAA were treated by PRP liquid associated with stanozolol for a course of 3 weeks treatment, and control group (17 cases of CAA) was treated by stanozolol alone. Results: Effective rate was 85. 3 % in treatment group, and that of control group was 58. 8 %,there was significant difference between them (P < 0. 05 ). Symptom remission of treatment group was earlier than that of control group.The difference of symptom scoring between two groups was significant (P < 0. 01 ). Blood cell had a distinct elevation after treatment with PRP associated with stanozolol, and had a significant difference in comparing with pretreatment in treatment group (P < 0. 01 ).Side effect of PRP was not found during treatment of CAA. Conclusion: PRP associated with stanozolol to treat CAA has an additional effect, it can accelerate symptom remission without any additional side effect.Original article on CJIM(Chin ) 1998; 18(6): 351