The properties of the warp knitted spacer fabrics for pressure reduction are experimentally investigated and compared to other materials.The influences of the different parameters, such as thickness, spacer yarn diame...The properties of the warp knitted spacer fabrics for pressure reduction are experimentally investigated and compared to other materials.The influences of the different parameters, such as thickness, spacer yarn diameter and connecting form are also analyzed and discussed. The results have shown that the spacer fabrics have very good properties for pressure reduction when they are used as soles, mattress or cushions.展开更多
Nanoparticles(NPs)have gained significant attention as a functional material due to their ability to effectively enhance pressure reduction in injection processes in ultra-low permeability reservoirs.NPs are typically...Nanoparticles(NPs)have gained significant attention as a functional material due to their ability to effectively enhance pressure reduction in injection processes in ultra-low permeability reservoirs.NPs are typically studied in controlled laboratory conditions,and their behavior in real-world,complex environments such as ultra-low permeability reservoirs,is not well understood due to the limited scope of their applications.This study investigates the efficacy and underlying mechanisms of NPs in decreasing injection pressure under various injection conditions(25—85℃,10—25 MPa).The results reveal that under optimal injection conditions,NPs effectively reduce injection pressure by a maximum of 22.77%in core experiment.The pressure reduction rate is found to be positively correlated with oil saturation and permeability,and negatively correlated with temperature and salinity.Furthermore,particle image velocimetry(PIV)experiments(25℃,atmospheric pressure)indicate that the pressure reduction is achieved by NPs through the reduction of wall shear resistance and wettability change.This work has important implications for the design of water injection strategies in ultra-low permeability reservoirs.展开更多
Carbon dots(CDs)show great potential as a new type of oil-displacing agent for unconventional oil and gas development.However,the instability and easy aggregation epitomize the challenges that accompany the applicatio...Carbon dots(CDs)show great potential as a new type of oil-displacing agent for unconventional oil and gas development.However,the instability and easy aggregation epitomize the challenges that accompany the application of CDs in high temperature and high salinity(HT/HS)reservoirs.In this research,novel benzene sulfonate-modified carbon dots(BS-CDs)with remarkable thermal stability and salt resistance were fabricated through an in-situ electrochemical exfoliation method.Molecular simulation verifies that the introduction of benzene sulfonate groups substantially strengthens the electrostatic repulsion between BS-CDs,leading to outstanding dispersibility and stability even at a temperature of 100℃ and salinity of 14×10^(4) mg/L.Core flooding tests show that 0.05 wt.%BS-CDs nanofluid can significantly reduce the water injection pressure by 50.00%and enhanced oil recovery(EOR)to 68.39%under HT/HS conditions.According to the atomic force microscopy(AFM)scanning results,the adhesion force between the core(after BS-CDs treatment)and oil decreased by 11.94 times,indicating that the hydrophilicity of the core surface was increased.In addition,the distribution of the adhesion force curve is more concentrated,which means that the micro-scale wettability of the core changes from oil-wet to more homogeneous water-wet.This study provides a feasible way for the development and application of good thermal stability and salt resistance CDs in unconventional reservoir development.展开更多
Switching expansion reduction(SER)uses a switch valve instead of the throttle valve to realize electronically controlled pressure reduction for high pressure pneumatics.A comprehensive and interactive pneumatic simula...Switching expansion reduction(SER)uses a switch valve instead of the throttle valve to realize electronically controlled pressure reduction for high pressure pneumatics.A comprehensive and interactive pneumatic simulation model according to the experimental setup of SER has been built.The mathematical model considers heat exchanges,source air pressure and temperature,environmental temperatures and heat transfer coefficients variations.In addition,the compensation for real gas effect is used in the model building.The comparison between experiments and simulations of SER indicates that,to compensate the real gas effect in high pressure discharging process,the thermal capacity of air supply container in simulation should be less than the actual value.The higher the pressure range,the greater the deviation.Simulated and experimental results are highly consistent within pressure reduction ratios ranging from 1.4 to 20 and output air mass flow rates ranging from 3.5 to 132 g/s,which verifies the high adaptability of SER and the validity of the mathematic model and the compensation method.展开更多
Pressure reduction station(PRS)is an essential facility in natural gas transmission,which owns the function of pressure reduction,demand-supply management and flow metering.However,a large number of PRSs are located i...Pressure reduction station(PRS)is an essential facility in natural gas transmission,which owns the function of pressure reduction,demand-supply management and flow metering.However,a large number of PRSs are located in off-grid areas and powered by battery equipment resulting in high maintenance costs.So,how to realize the energy independence of these PRSs is an urgent issue to be solved.Therefore,the natural gas fired thermoelectric generation(FTEG)module,including gas flue,cover,TEGs and heat radiators,is designed for PRS in off-grid areas.Phase change material is introduced into the FTEG module to change the operation mode from continuous mode into a periodic mode,and the prototype of the FTEG module is built to discuss the generation performance in different modes.The results show that the generation efficiency of the FTEG module is improved by 63%in periodic mode compared with the continuous mode.Then,the numerical model is established to investigate the impacts of air coefficient,cold-side heat radiator and number of TEGs on the module performance.It found that the impacts of cold-side heat radiator and the number of TEGs are more significant than those of the air coefficient.After adjusting these key parameters,an optimized FTEG module with 32 TEGs is proposed,which has an average power generation of 16.4 W and a heat collection efficiency of 84.6%.Eventually,3 to 6 modules can be connected in series to meet the power requirement of 50 W to 100 W for PRS.This high-performance FTEG module can accelerate the process of achieving the energy independence of PRS and promote its application in mesoscale equipment.展开更多
Objective:To evaluate the efficacy of combination perindopril/amlodipine tablets in patients with high-altitude hypertension who were previously unable to control their blood pressure with monotherapy.Methods:A total ...Objective:To evaluate the efficacy of combination perindopril/amlodipine tablets in patients with high-altitude hypertension who were previously unable to control their blood pressure with monotherapy.Methods:A total of 151 patients with high-altitude hypertension whose blood pressure remained inadequately controlled with previous monotherapy were enrolled in this study.All patients received an 8-week treatment with a combination of perindopril/amlodipine tablets,consisting of perindopril 10 mg/day and amlodipine 5 mg/day.Blood pressure measurements,including both diastolic and systolic pressures,were taken at baseline,and after 2,4,6,and 8 weeks of treatment.Results:After 8 weeks of treatment,there was a significant reduction in both average systolic and diastolic blood pressure compared to baseline(P<0.0001).Specifically,the average systolic blood pressure decreased by 24.45±13.75 mmHg,and the average diastolic blood pressure decreased by 13.37±8.40 mmHg.The overall heart rate showed no significant changes during the treatment period.Conclusion:A combination of perindopril/amlodipine tablets significantly improved blood pressure control in patients with high-altitude hypertension after 8 weeks of treatment.These results support the efficacy of combination perindopril/amlodipine as a viable treatment option for high-altitude hypertension.展开更多
A test bench of ABS/ASR integrated hydraulic system is developed by using pulse-width modulation (PWM) technology. The effective duty ratio range of ABS outlet valve has been tested in PWM control. With 50 Hz carrie...A test bench of ABS/ASR integrated hydraulic system is developed by using pulse-width modulation (PWM) technology. The effective duty ratio range of ABS outlet valve has been tested in PWM control. With 50 Hz carrier wave frequency, the tests are performed to determine the correspondence between duty ratio and the wheel cylinder pressure variation. The duty ratio range of ABS outlet valve in PWM control is determined and an experimental model of pressure reduction velocity (PRV) of wheel cylinder using PWM control is established. By comparison and test of the experimental model and realization of controlling the duty ratio of ABS outlet valves, the fine regulation of wheel cylinder PRV is realized in the working of ABS/ASR braking regulation, which is important and valuable to the improvement of the ABS/ASR controlling effect.展开更多
New glucose-lowering agents reduce liver enzyme levels and blood pressure(BP).Whether this finding can be extended to non-alcoholic fatty liver disease(NAFLD)patients,in whom a bidirectional association of NAFLD measu...New glucose-lowering agents reduce liver enzyme levels and blood pressure(BP).Whether this finding can be extended to non-alcoholic fatty liver disease(NAFLD)patients,in whom a bidirectional association of NAFLD measures and BP has been also demonstrated,remains by and large unknown.展开更多
AIM:To evaluate the efficacy and safety of high-dose ultrasound cyclo-plasty(UCP)for the treatment of refractory glaucoma in Chinese patients.METHODS:In this 6-month retrospective study,37 eyes of 37 patients sufferin...AIM:To evaluate the efficacy and safety of high-dose ultrasound cyclo-plasty(UCP)for the treatment of refractory glaucoma in Chinese patients.METHODS:In this 6-month retrospective study,37 eyes of 37 patients suffering from severe glaucoma with uncontrolled intraocular pressure(IOP)of≥21 mm Hg underwent 8-s ultrasonic cyclocoagulation with ten active piezoelectric elements.A complete ophthalmic examination was performed before and at 1 d,1,3,6 mo after UCP.Therapeutic success was defined as IOP reduction from baseline≥20%and IOP≥5 mm Hg without adding new glaucoma medication compare to baseline at the 6-month follow-up visit.In addition to mean IOP at each followup visit,medications used and complications were also detected and compared to baseline.RESULTS:After UCP procedure,the mean IOP was significantly reduced(P<0.01)from the preoperative 44.1±11.9 mm Hgto postoperative 26.7±11.8 mm Hg at 3 mo,and 30.4±14.5 mm Hg at 6 mo.The overall mean IOP reductions achieved at 3 and 6 mo were 39%and 31%compared to baseline IOP.Sixty-one percent of patients responded well to UCP treatment with a mean IOP reduction of 48%at 3 mo and 42%at 6 mo.Ocular pain in most of patients were alleviated.No serious intraoperative or postoperative complications occurred.CONCLUSION:High-dose UCP treatment is an effective and safe procedure to reduce IOP in Chinese patients with severe glaucoma.展开更多
Switching expansion reduction(SER) uses a switch valve to substitute the throttle valve to reduce pressure for high pressure pneumatics.The experiments indicate that the simulation model well predicts the actual chara...Switching expansion reduction(SER) uses a switch valve to substitute the throttle valve to reduce pressure for high pressure pneumatics.The experiments indicate that the simulation model well predicts the actual characteristics.The heat transfers and polytropic exponents of the air in expansion tank and supply tanks of SER have been studied on the basis of the experiments and the simulation model.Through the mathematical reasoning in this paper,the polytropic exponent can be calculated by the air mass,heat,and work exchanges of the pneumatic container.For the air in a constant volume tank,when the heat-absorption is large enough to raise air temperature in discharging process,the polytropic exponent is less than 1;when the air is experiencing a discharging and heat-releasing process,the polytropic exponent exceeds the specific heat ratio(the value of 1.4).展开更多
AIM: To investigate the change of anterior chamber angle morphology and intraocular pressure (lOP) reduction after cataract surgery in patients with normal-tension glaucoma (NTG) using swept-source optical cohere...AIM: To investigate the change of anterior chamber angle morphology and intraocular pressure (lOP) reduction after cataract surgery in patients with normal-tension glaucoma (NTG) using swept-source optical coherence tomography (SS-OCT). METHODS: This prospective, comparative, observational study recruited patients into two groups. Group 1 was the control group including normal subjects except those with cataracts (cataract group, n=67 eyes of 67 patients), and group 2 was NTG group including patients who were diagnosed with NTG and cataracts (n=43 eyes of 43 patients), which were treated with phacoemulsification and intraocular lens implantation. Before surgery, and at postoperative 1 and 6too, anterior chamber angles were evaluated by SS-OCT under dark conditions using three- dimensional angle analysis scan protocol. Angle opening distance (AOD), angle recess area (ARA), and trabecular- iris surface area (TISA) at four quadrants (temporal, nasal, superior, and inferior) were calculated automatically by SS-OGT, after the observer marked scleral spurs. RESULTS: A total of 106 patients (54 males and 52 females) were enrolled in the study. Angle parameters, AOD, ARA, and TISA were increased after surgery in both groups. However, changes of angle parameters were only significant in group 2. In group 2, preoperative lOP was 13.2+2.9 mm Hg, and postoperative lOP at 1 and 6mo were 10.5+3.0 and 10.7+2.8 mm Hg, respectively. In group 1, preoperative lOP was 12.42.8 mm Hg, and postoperative lOP at 1 and 6mo were 11.6+2.5 and 12.0+2.8 mm Hg, respectively. After cataract surgery, angle parameters changed significantly while IOP significantly reduced and was maintained in group 2 (P〈0.001). The changes in angle parameters (&AOD500, ATISAS00 at temporal; &AOD500, S, RA500 at nasal) were linearly correlated with postoperative IOP changes. CONCLUSION: Cataract surgery may have improved antedor chamber angle parameters and decreased lOP in NTG patients.展开更多
The energy balance, air internal energy, enthalpy and exergy transfers of high pressure switching expansion reduction (SER) are comparatively analyzed in this paper to give a better understanding about the exergy an...The energy balance, air internal energy, enthalpy and exergy transfers of high pressure switching expansion reduction (SER) are comparatively analyzed in this paper to give a better understanding about the exergy analysis and its difference between energy conversion analyses for the pneumatics. In SER, the exergy transfer efficiency is much lower than the enthalpy efficiency. The enthalpy efficiency is primarily related to the initial pressure of supply tanks, and the exergy efficiency is primarily related to the pressure reduction ratios. Heat transfers increase the internal energy, enthalpy and exergy of air; the influence on exergy is relatively small. The total enthalpy in SER decreases as the air temperature decreases in the expansion process of the air. And exergy loss is primarily related to the irreversible process of isenthalpic throttling but not energy conversion. Based on the analyses, to improve the exergy efficiency of the pneumatics, the pressure reduction without power output should be avoided.展开更多
The adhesion of fine iron ore particles during fluidized bed reduction was studied using pressurized visible fluidized bed laboratory equipment.The results showed that the optimal operating parameters for pure hydroge...The adhesion of fine iron ore particles during fluidized bed reduction was studied using pressurized visible fluidized bed laboratory equipment.The results showed that the optimal operating parameters for pure hydrogen reduction under high pressure were reduction temperature of 1073 K,particle size of 0.18-0.66 mm,pure H_(2) linear velocity of 0.8 m/s,reduction pressure of 200 kPa,and reduction time of 50 min.When plastic particles were mixed into the fluidized bed,the optimal parameters were reduction temperature of 973 K,particle size of 0.18-0.66 mm,pure H_(2) linear velocity of 0.8 m/s,reduction pressure of 100 kPa,mass content of plastic particles of 8%,and reduction time of 65 min.The chemical reaction resistance is much higher than the inner diffusion resistance at the initial stage of the reaction,whereas,in later stage,the inner diffusion resistance exceeds the chemical reaction resistance.The contact area of iron atoms or iron whiskers gradually decreases with the increase in reduction pressure from 0.20 to 0.45 MPa,and the sticking trend gradually decreases.Adding plastic particles in the fluidized reduction process of fine iron ore can effectively inhibit the adhesion among fine iron ore particles.展开更多
The correction method uses the static pressures measured near the tunnelwalls during model tests as boundary conditions. It is required that the flow near thewalls is subsonic and the freestream Mach number is less th...The correction method uses the static pressures measured near the tunnelwalls during model tests as boundary conditions. It is required that the flow near thewalls is subsonic and the freestream Mach number is less than 1. It is still valid whenthere are shock waves and supersonic pockets near the model as long as shock waves donot extend to walls, and the method is applicable to various ventilated wall or solid walltest sections. Corrections for three models tested abroad are in quite good agreementwith NASA's results, which are obtained by a nonhnear correction method. Thepresnet method has been apphed to B737 inodel tcsted in CARDC 1.2 m wind tunnel.The results show that this method is suitable for transonic wall interference correctionfor high aspect ratio airplane tests.展开更多
The present study aims to investigate the effect of temporary cerebrospinal fluid pressure(CSFP) reduction on optic nerve head(ONH) and macular vessel density(VD) using optical coherence tomography angiography.Forty-f...The present study aims to investigate the effect of temporary cerebrospinal fluid pressure(CSFP) reduction on optic nerve head(ONH) and macular vessel density(VD) using optical coherence tomography angiography.Forty-four eyes of 44 adults with diagnostic lumbar puncture and CSFP reduction were recruited.Thirty-two eyes of 32 healthy volunteers were controls.ONH and macular VD images were evaluated differences between baseline and after CSFP reduction.The results showed that the mean CSFP decreased from(11.6±2.1) mm Hg to(8.2±3.4) mm Hg(P<0.001).VD in the macular regions decreased significantly after CSFP reduction in the study group(all P<0.05).The control group showed no significant changes in macular VD(all P>0.05).In the study group,decreased VD in the macular parainferior region was associated with CSFP reduction(R^(2)=0.192,P=0.003),the reduction of macular VD in parafoveal(R^(2)=0.098,P=0.018),parainferior(R^(2)=0.104,P=0.021),parasuperior(R^(2)=0.059,P=0.058),paranasal(R^(2)=0.057,P=0.042),paratemporal(R^(2)=0.079,P=0.026) was associated with mean ocular perfusion pressure decrease following CSFP reduction.ONH vessel density did not differ after CSFP reduction(all P>0.05).In conclusion,macular vessel density decreased in association with CSFP reduction.Retinal vessel density in the macular region is more sensitive than that in peripapillary region after CSFP reduction.展开更多
文摘The properties of the warp knitted spacer fabrics for pressure reduction are experimentally investigated and compared to other materials.The influences of the different parameters, such as thickness, spacer yarn diameter and connecting form are also analyzed and discussed. The results have shown that the spacer fabrics have very good properties for pressure reduction when they are used as soles, mattress or cushions.
基金supported by the National Natural Science Foundation of China(Nos.52074249,U1663206,52204069)Fundamental Research Funds for the Central Universities。
文摘Nanoparticles(NPs)have gained significant attention as a functional material due to their ability to effectively enhance pressure reduction in injection processes in ultra-low permeability reservoirs.NPs are typically studied in controlled laboratory conditions,and their behavior in real-world,complex environments such as ultra-low permeability reservoirs,is not well understood due to the limited scope of their applications.This study investigates the efficacy and underlying mechanisms of NPs in decreasing injection pressure under various injection conditions(25—85℃,10—25 MPa).The results reveal that under optimal injection conditions,NPs effectively reduce injection pressure by a maximum of 22.77%in core experiment.The pressure reduction rate is found to be positively correlated with oil saturation and permeability,and negatively correlated with temperature and salinity.Furthermore,particle image velocimetry(PIV)experiments(25℃,atmospheric pressure)indicate that the pressure reduction is achieved by NPs through the reduction of wall shear resistance and wettability change.This work has important implications for the design of water injection strategies in ultra-low permeability reservoirs.
基金the National Key Research and Development Program of China(No.2019YFA0708700)the Innovation fund project for graduate student of China University of Petroleum(East China)(No.22CX04050A)the Fundamental Research Funds for the Central Universities,the China National Petroleum Corporation Innovation Found(No.2021DQ02-0205).
文摘Carbon dots(CDs)show great potential as a new type of oil-displacing agent for unconventional oil and gas development.However,the instability and easy aggregation epitomize the challenges that accompany the application of CDs in high temperature and high salinity(HT/HS)reservoirs.In this research,novel benzene sulfonate-modified carbon dots(BS-CDs)with remarkable thermal stability and salt resistance were fabricated through an in-situ electrochemical exfoliation method.Molecular simulation verifies that the introduction of benzene sulfonate groups substantially strengthens the electrostatic repulsion between BS-CDs,leading to outstanding dispersibility and stability even at a temperature of 100℃ and salinity of 14×10^(4) mg/L.Core flooding tests show that 0.05 wt.%BS-CDs nanofluid can significantly reduce the water injection pressure by 50.00%and enhanced oil recovery(EOR)to 68.39%under HT/HS conditions.According to the atomic force microscopy(AFM)scanning results,the adhesion force between the core(after BS-CDs treatment)and oil decreased by 11.94 times,indicating that the hydrophilicity of the core surface was increased.In addition,the distribution of the adhesion force curve is more concentrated,which means that the micro-scale wettability of the core changes from oil-wet to more homogeneous water-wet.This study provides a feasible way for the development and application of good thermal stability and salt resistance CDs in unconventional reservoir development.
基金Project(51205421)supported by the National Natural Science Foundation of ChinaProject(2012M521647)supported by the Postdoctoral Science Foundation of China
文摘Switching expansion reduction(SER)uses a switch valve instead of the throttle valve to realize electronically controlled pressure reduction for high pressure pneumatics.A comprehensive and interactive pneumatic simulation model according to the experimental setup of SER has been built.The mathematical model considers heat exchanges,source air pressure and temperature,environmental temperatures and heat transfer coefficients variations.In addition,the compensation for real gas effect is used in the model building.The comparison between experiments and simulations of SER indicates that,to compensate the real gas effect in high pressure discharging process,the thermal capacity of air supply container in simulation should be less than the actual value.The higher the pressure range,the greater the deviation.Simulated and experimental results are highly consistent within pressure reduction ratios ranging from 1.4 to 20 and output air mass flow rates ranging from 3.5 to 132 g/s,which verifies the high adaptability of SER and the validity of the mathematic model and the compensation method.
基金jointly supported by the Natural Science Foundation of China(52176007)the Fundamental Research Funds for the Central Universities(2016YXMS048)Basic Research Program of Shenzhen Science and Technology(JCYJ20210324115611030)。
文摘Pressure reduction station(PRS)is an essential facility in natural gas transmission,which owns the function of pressure reduction,demand-supply management and flow metering.However,a large number of PRSs are located in off-grid areas and powered by battery equipment resulting in high maintenance costs.So,how to realize the energy independence of these PRSs is an urgent issue to be solved.Therefore,the natural gas fired thermoelectric generation(FTEG)module,including gas flue,cover,TEGs and heat radiators,is designed for PRS in off-grid areas.Phase change material is introduced into the FTEG module to change the operation mode from continuous mode into a periodic mode,and the prototype of the FTEG module is built to discuss the generation performance in different modes.The results show that the generation efficiency of the FTEG module is improved by 63%in periodic mode compared with the continuous mode.Then,the numerical model is established to investigate the impacts of air coefficient,cold-side heat radiator and number of TEGs on the module performance.It found that the impacts of cold-side heat radiator and the number of TEGs are more significant than those of the air coefficient.After adjusting these key parameters,an optimized FTEG module with 32 TEGs is proposed,which has an average power generation of 16.4 W and a heat collection efficiency of 84.6%.Eventually,3 to 6 modules can be connected in series to meet the power requirement of 50 W to 100 W for PRS.This high-performance FTEG module can accelerate the process of achieving the energy independence of PRS and promote its application in mesoscale equipment.
文摘Objective:To evaluate the efficacy of combination perindopril/amlodipine tablets in patients with high-altitude hypertension who were previously unable to control their blood pressure with monotherapy.Methods:A total of 151 patients with high-altitude hypertension whose blood pressure remained inadequately controlled with previous monotherapy were enrolled in this study.All patients received an 8-week treatment with a combination of perindopril/amlodipine tablets,consisting of perindopril 10 mg/day and amlodipine 5 mg/day.Blood pressure measurements,including both diastolic and systolic pressures,were taken at baseline,and after 2,4,6,and 8 weeks of treatment.Results:After 8 weeks of treatment,there was a significant reduction in both average systolic and diastolic blood pressure compared to baseline(P<0.0001).Specifically,the average systolic blood pressure decreased by 24.45±13.75 mmHg,and the average diastolic blood pressure decreased by 13.37±8.40 mmHg.The overall heart rate showed no significant changes during the treatment period.Conclusion:A combination of perindopril/amlodipine tablets significantly improved blood pressure control in patients with high-altitude hypertension after 8 weeks of treatment.These results support the efficacy of combination perindopril/amlodipine as a viable treatment option for high-altitude hypertension.
基金the National Natural Science Foundation of China (50122155)
文摘A test bench of ABS/ASR integrated hydraulic system is developed by using pulse-width modulation (PWM) technology. The effective duty ratio range of ABS outlet valve has been tested in PWM control. With 50 Hz carrier wave frequency, the tests are performed to determine the correspondence between duty ratio and the wheel cylinder pressure variation. The duty ratio range of ABS outlet valve in PWM control is determined and an experimental model of pressure reduction velocity (PRV) of wheel cylinder using PWM control is established. By comparison and test of the experimental model and realization of controlling the duty ratio of ABS outlet valves, the fine regulation of wheel cylinder PRV is realized in the working of ABS/ASR braking regulation, which is important and valuable to the improvement of the ABS/ASR controlling effect.
文摘New glucose-lowering agents reduce liver enzyme levels and blood pressure(BP).Whether this finding can be extended to non-alcoholic fatty liver disease(NAFLD)patients,in whom a bidirectional association of NAFLD measures and BP has been also demonstrated,remains by and large unknown.
基金Supported by the Anhui Medical University Research Fund Project(No.2018xkj042)the Second Hospital of Anhui Medical University Incubation Project of NSFC(No.2019GQFY04)Science and Technology New Star Training Project(No.2018KA08)。
文摘AIM:To evaluate the efficacy and safety of high-dose ultrasound cyclo-plasty(UCP)for the treatment of refractory glaucoma in Chinese patients.METHODS:In this 6-month retrospective study,37 eyes of 37 patients suffering from severe glaucoma with uncontrolled intraocular pressure(IOP)of≥21 mm Hg underwent 8-s ultrasonic cyclocoagulation with ten active piezoelectric elements.A complete ophthalmic examination was performed before and at 1 d,1,3,6 mo after UCP.Therapeutic success was defined as IOP reduction from baseline≥20%and IOP≥5 mm Hg without adding new glaucoma medication compare to baseline at the 6-month follow-up visit.In addition to mean IOP at each followup visit,medications used and complications were also detected and compared to baseline.RESULTS:After UCP procedure,the mean IOP was significantly reduced(P<0.01)from the preoperative 44.1±11.9 mm Hgto postoperative 26.7±11.8 mm Hg at 3 mo,and 30.4±14.5 mm Hg at 6 mo.The overall mean IOP reductions achieved at 3 and 6 mo were 39%and 31%compared to baseline IOP.Sixty-one percent of patients responded well to UCP treatment with a mean IOP reduction of 48%at 3 mo and 42%at 6 mo.Ocular pain in most of patients were alleviated.No serious intraoperative or postoperative complications occurred.CONCLUSION:High-dose UCP treatment is an effective and safe procedure to reduce IOP in Chinese patients with severe glaucoma.
基金supported by the National Natural Science Foundation of China (No.50575202)
文摘Switching expansion reduction(SER) uses a switch valve to substitute the throttle valve to reduce pressure for high pressure pneumatics.The experiments indicate that the simulation model well predicts the actual characteristics.The heat transfers and polytropic exponents of the air in expansion tank and supply tanks of SER have been studied on the basis of the experiments and the simulation model.Through the mathematical reasoning in this paper,the polytropic exponent can be calculated by the air mass,heat,and work exchanges of the pneumatic container.For the air in a constant volume tank,when the heat-absorption is large enough to raise air temperature in discharging process,the polytropic exponent is less than 1;when the air is experiencing a discharging and heat-releasing process,the polytropic exponent exceeds the specific heat ratio(the value of 1.4).
文摘AIM: To investigate the change of anterior chamber angle morphology and intraocular pressure (lOP) reduction after cataract surgery in patients with normal-tension glaucoma (NTG) using swept-source optical coherence tomography (SS-OCT). METHODS: This prospective, comparative, observational study recruited patients into two groups. Group 1 was the control group including normal subjects except those with cataracts (cataract group, n=67 eyes of 67 patients), and group 2 was NTG group including patients who were diagnosed with NTG and cataracts (n=43 eyes of 43 patients), which were treated with phacoemulsification and intraocular lens implantation. Before surgery, and at postoperative 1 and 6too, anterior chamber angles were evaluated by SS-OCT under dark conditions using three- dimensional angle analysis scan protocol. Angle opening distance (AOD), angle recess area (ARA), and trabecular- iris surface area (TISA) at four quadrants (temporal, nasal, superior, and inferior) were calculated automatically by SS-OGT, after the observer marked scleral spurs. RESULTS: A total of 106 patients (54 males and 52 females) were enrolled in the study. Angle parameters, AOD, ARA, and TISA were increased after surgery in both groups. However, changes of angle parameters were only significant in group 2. In group 2, preoperative lOP was 13.2+2.9 mm Hg, and postoperative lOP at 1 and 6mo were 10.5+3.0 and 10.7+2.8 mm Hg, respectively. In group 1, preoperative lOP was 12.42.8 mm Hg, and postoperative lOP at 1 and 6mo were 11.6+2.5 and 12.0+2.8 mm Hg, respectively. After cataract surgery, angle parameters changed significantly while IOP significantly reduced and was maintained in group 2 (P〈0.001). The changes in angle parameters (&AOD500, ATISAS00 at temporal; &AOD500, S, RA500 at nasal) were linearly correlated with postoperative IOP changes. CONCLUSION: Cataract surgery may have improved antedor chamber angle parameters and decreased lOP in NTG patients.
基金the National Natural Science Foundation of China(No.50575202)
文摘The energy balance, air internal energy, enthalpy and exergy transfers of high pressure switching expansion reduction (SER) are comparatively analyzed in this paper to give a better understanding about the exergy analysis and its difference between energy conversion analyses for the pneumatics. In SER, the exergy transfer efficiency is much lower than the enthalpy efficiency. The enthalpy efficiency is primarily related to the initial pressure of supply tanks, and the exergy efficiency is primarily related to the pressure reduction ratios. Heat transfers increase the internal energy, enthalpy and exergy of air; the influence on exergy is relatively small. The total enthalpy in SER decreases as the air temperature decreases in the expansion process of the air. And exergy loss is primarily related to the irreversible process of isenthalpic throttling but not energy conversion. Based on the analyses, to improve the exergy efficiency of the pneumatics, the pressure reduction without power output should be avoided.
基金the National Natural Science Foundation of China(No.51974001)the University outstanding young talents funding program(No.gxyq2019016).
文摘The adhesion of fine iron ore particles during fluidized bed reduction was studied using pressurized visible fluidized bed laboratory equipment.The results showed that the optimal operating parameters for pure hydrogen reduction under high pressure were reduction temperature of 1073 K,particle size of 0.18-0.66 mm,pure H_(2) linear velocity of 0.8 m/s,reduction pressure of 200 kPa,and reduction time of 50 min.When plastic particles were mixed into the fluidized bed,the optimal parameters were reduction temperature of 973 K,particle size of 0.18-0.66 mm,pure H_(2) linear velocity of 0.8 m/s,reduction pressure of 100 kPa,mass content of plastic particles of 8%,and reduction time of 65 min.The chemical reaction resistance is much higher than the inner diffusion resistance at the initial stage of the reaction,whereas,in later stage,the inner diffusion resistance exceeds the chemical reaction resistance.The contact area of iron atoms or iron whiskers gradually decreases with the increase in reduction pressure from 0.20 to 0.45 MPa,and the sticking trend gradually decreases.Adding plastic particles in the fluidized reduction process of fine iron ore can effectively inhibit the adhesion among fine iron ore particles.
文摘The correction method uses the static pressures measured near the tunnelwalls during model tests as boundary conditions. It is required that the flow near thewalls is subsonic and the freestream Mach number is less than 1. It is still valid whenthere are shock waves and supersonic pockets near the model as long as shock waves donot extend to walls, and the method is applicable to various ventilated wall or solid walltest sections. Corrections for three models tested abroad are in quite good agreementwith NASA's results, which are obtained by a nonhnear correction method. Thepresnet method has been apphed to B737 inodel tcsted in CARDC 1.2 m wind tunnel.The results show that this method is suitable for transonic wall interference correctionfor high aspect ratio airplane tests.
文摘The present study aims to investigate the effect of temporary cerebrospinal fluid pressure(CSFP) reduction on optic nerve head(ONH) and macular vessel density(VD) using optical coherence tomography angiography.Forty-four eyes of 44 adults with diagnostic lumbar puncture and CSFP reduction were recruited.Thirty-two eyes of 32 healthy volunteers were controls.ONH and macular VD images were evaluated differences between baseline and after CSFP reduction.The results showed that the mean CSFP decreased from(11.6±2.1) mm Hg to(8.2±3.4) mm Hg(P<0.001).VD in the macular regions decreased significantly after CSFP reduction in the study group(all P<0.05).The control group showed no significant changes in macular VD(all P>0.05).In the study group,decreased VD in the macular parainferior region was associated with CSFP reduction(R^(2)=0.192,P=0.003),the reduction of macular VD in parafoveal(R^(2)=0.098,P=0.018),parainferior(R^(2)=0.104,P=0.021),parasuperior(R^(2)=0.059,P=0.058),paranasal(R^(2)=0.057,P=0.042),paratemporal(R^(2)=0.079,P=0.026) was associated with mean ocular perfusion pressure decrease following CSFP reduction.ONH vessel density did not differ after CSFP reduction(all P>0.05).In conclusion,macular vessel density decreased in association with CSFP reduction.Retinal vessel density in the macular region is more sensitive than that in peripapillary region after CSFP reduction.