期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
Stability of rat models of fluid percussion-induced traumatic brain injury: comparison of three different impact forces 被引量:1
1
作者 Yun-peng Lin Rong-cai Jiang Jian-ning Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第7期1088-1094,共7页
Fluid percussion-induced traumatic brain injury models have been widely used in experimental research for years. In an experiment, the stability of impaction is inevitably affected by factors such as the appearance of... Fluid percussion-induced traumatic brain injury models have been widely used in experimental research for years. In an experiment, the stability of impaction is inevitably affected by factors such as the appearance of liquid spikes. Management of impact pressure is a crucial factor that determines the stability of these models, and direction of impact control is another basic element. To improve experimental stability, we calculated a pressure curve by generating repeated impacts using a fluid percussion device at different pendulum angles. A stereotactic frame was used to control the direction of impact. We produced stable and reproducible models, including mild, moderate, and severe traumatic brain injury, using the MODEL01-B device at pendulum angles of 6°, 11° and 13°, with corresponding impact force values of 1.0 ± 0.11 atm(101.32 ± 11.16 k Pa), 2.6 ± 0.16 atm(263.44 ± 16.21 k Pa), and 3.6 ± 0.16 atm(364.77 ± 16.21 k Pa), respectively. Behavioral tests, hematoxylin-eosin staining, and magnetic resonance imaging revealed that models for different degrees of injury were consistent with the clinical properties of mild, moderate, and severe craniocerebral injuries. Using this method, we established fluid percussion models for different degrees of injury and stabilized pathological features based on precise power and direction control. 展开更多
关键词 nerve regeneration traumatic brain injury fluid percussion impact force pressure curve head fixed impact peak animal models neural regeneration
下载PDF
CFD modeling of pressure drop and drag coefficient in fixed beds:Wall effects 被引量:6
2
作者 Rupesh K.Reddy Jyeshtharaj B.Joshi 《Particuology》 SCIE EI CAS CSCD 2010年第1期37-43,共7页
Simulations of fixed beds having column to particle diameter ratio (D/dp) of 3, 5 and 10 were performed in the creeping, transition and turbulent flow regimes, where Reynolds number (dpVLρL/μL) was varied from 0... Simulations of fixed beds having column to particle diameter ratio (D/dp) of 3, 5 and 10 were performed in the creeping, transition and turbulent flow regimes, where Reynolds number (dpVLρL/μL) was varied from 0.1 to 10,000. The deviations from Ergun's equation due to the wall effects, which are important in D/dp 〈 15 beds were well explained by the CFD simulations. Thus, an increase in the pressure drop was observed due to the wall friction in the creeping flow, whereas, in turbulent regime a decrease in the pressure drop was observed due to the channeling near the wall. It was observed that, with an increase in the D/dp ratio, the effect of wall on drag coefficient decreases and drag coefficient nearly approaches to Ergun's equation. The predicted drag coefficient values were in agreement with the experimental results reported in the literature, in creeping flow regime, whereas in turbulent flow the difference was within 10-15%. 展开更多
关键词 Computational fluid dynamics Fixed bed Wall effects pressure drop Drag coefficient
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部