Cardiac primary tumors are uncommon with an estimated prevalence between 0.17%and 0.19%.[1,2]Cardiac lipoma are extremely rare representing only 10%?19%of primary cardiac tumors and only few are symptomatic,depending ...Cardiac primary tumors are uncommon with an estimated prevalence between 0.17%and 0.19%.[1,2]Cardiac lipoma are extremely rare representing only 10%?19%of primary cardiac tumors and only few are symptomatic,depending on their location within the heart.[3,4]They originate from the subendocardium(50%),subepicardium(25%)or myocardium(25%)and with different sizes and locations.[5]Few cases of sudden death due to primary cardiac tumors are reported in literature(0.0025%);in these cases,conductive and haemodinamic abnormalities have been indicated as the cause of death.展开更多
Primary cardiac tumors are extremely uncommon.Here,we report the case of a patient with a primary left ventricular interstitial tumor presenting with hemodynamically unstable ventricular tachycardia.In response to hem...Primary cardiac tumors are extremely uncommon.Here,we report the case of a patient with a primary left ventricular interstitial tumor presenting with hemodynamically unstable ventricular tachycardia.In response to hemodynamically unstable ventricular tachycardia,an implantable cardioverter-defibrillator was inserted.One month after defibrillator implantation,the patient developed episodes of high ventricular tachycardia that could not be effectively terminated by catheter radiofrequency ablation,thus further confirming that the ventricular tachycardia was induced by the left ventricular interstitial tumor.The patient is doing well on medical therapy to date.展开更多
Objective: Through this surgical series, we present the epidemiological and anatomical-clinical aspects and the surgical results concerning patients operated on for a primary cardiac tumor at the Abidjan Heart Institu...Objective: Through this surgical series, we present the epidemiological and anatomical-clinical aspects and the surgical results concerning patients operated on for a primary cardiac tumor at the Abidjan Heart Institute. Materials and Method: This is a retrospective descriptive study covering the period of January 1982 to December 2022, based on the medical records of patients operated on for a primary cardiac tumor at the Abidjan Heart Institute. Results: Twenty-seven (27) patients underwent surgery for a primary cardiac tumor, including 14 women and 13 men with a mean age of 41.5 years (range 19 - 76 years). The main circumstances of discovery were exertional dyspnea, palpitation and syncope or pseudo-syncope. The main site was the septal wall of the left atrium. The diagnosis of myxoma was confirmed by pathological examination of the surgical specimen in 96.3% (n = 24) of the patients and it was a malignant large cell immunoblastic lymphoma of the myocardium in 3.7% (n = 1) of the patients. The mean largest diameter was 46.1 mm. The postoperative course was marked by an ischaemic stroke (n = 1);recurrence of a left atrial myxoma 5 years after the first tumor removal (n = 1). Two cases of death were noted, one due to the evolution of immunoblastic large cell lymphoma and the other due to an extracorporeal circulation accident. Conclusion: Almost all primary cardiac tumors operated on in Abidjan are myxomas. The circumstances of the discovery of these cardiac tumors are multiple and varied but dominated by exertional dyspnea, palpitation and syncope. Whatever their histological type, primary cardiac tumors are serious affections, in view of the haemodynamic and rhythmic disorders they cause.展开更多
Objective To analyze the experience of treatment strategies for pediatric patients with primary cardiac tumors. Methods The clinical data of 27 patients with primary cardiac tumors which detected by echocardiography f...Objective To analyze the experience of treatment strategies for pediatric patients with primary cardiac tumors. Methods The clinical data of 27 patients with primary cardiac tumors which detected by echocardiography from May 1999 to May 2009 was analyzed retrospectively. There were 20 male and 7 female patients,aged from 24 d to 12. 6 years. There were 59. 2% less than 1 year old at the time of diagnosis. A single tumor were present in 22 cases and multiple in 5 cases. Surgery was performed on 22 patients due to the varied展开更多
<span style="font-family:""><span style="font-family:Verdana;">Primary cardiac lymphoma (PCL) is a rare entity that comprises only 1% - 2% of all cardiac tumors. Due to their scarc...<span style="font-family:""><span style="font-family:Verdana;">Primary cardiac lymphoma (PCL) is a rare entity that comprises only 1% - 2% of all cardiac tumors. Due to their scarcity and variable clinical presentation, early diagnosis is challenging. In this series, three cases of PCL from a single institution are described, which highlight the spectrum of presenting features and emphasize common principles. In the first case, a 73-year-old male who presented with dyspnea was found to have a 12.1 cm mass in the right ventricle. Biopsy via cardiac catheterization revealed diffuse large B cell ly</span><span style="font-family:Verdana;">mphoma (DLBCL). He was treated with chemoimmunotherapy and s</span><span style="font-family:Verdana;">urvived for two months. The second case describes a 55-year-old female who presented with chest pain. Imaging revealed a 3.1 cm right atrial mass and bilateral pleural effusions, with cytology from the latter demonstrating DLBCL. She was lost to follow up after three cycles of chemoimmunotherapy. In the last case, an 80-year-old female presented with weakness. A 4.0 cm mass was discovered in the right atrium and the patient expired shortly after admission. Autopsy confirmed the diagnosis of DLBCL. These case summaries are follo</span><span style="font-family:Verdana;">wed by a review of the clinical presentation, diagnostic approach, an</span><span style="font-family:Verdana;">d treatment outcomes of PCL.展开更多
目的基于文献计量学方法,分析国内外原发心脏恶性肿瘤的研究现状,并预测其未来发展趋势。方法分别检索2004年1月1日—2024年6月1日中国知网(CNKI)和Web of Science(WOS)数据库核心合集中有关“原发心脏恶性肿瘤(primary cardiac maligna...目的基于文献计量学方法,分析国内外原发心脏恶性肿瘤的研究现状,并预测其未来发展趋势。方法分别检索2004年1月1日—2024年6月1日中国知网(CNKI)和Web of Science(WOS)数据库核心合集中有关“原发心脏恶性肿瘤(primary cardiac malignant tumor)”的文献。统计发文量,并基于CiteSpace和VOSviewer软件分析纳入文献的国家发文量、作者情况、作者机构、发文期刊,以及关键词的共现、聚类和突现情况。结果CNKI数据库和WOS核心合集中分别纳入文献312篇和775篇。WOS核心合集数据显示,中国的发文量位居全球第2位,国际间的合作相对较少(中心性为0.01)。CNKI中高发文量作者以陈东、徐志云和宋书田为代表;WOS核心合集中则以Reardon Michael J、Gaudino Mario为代表,有一定数量的中国研究者的发文,中国学者缺乏研究合作与持续的学术产出。关键词图谱分析显示,“病理分型”“超声心动图”“外科手术”等是国内外长期研究焦点;近年,有关化学治疗与分子机制的研究增多,免疫检查点抑制剂(immune checkpoint inhibitors,ICIs)等免疫治疗方案已逐步应用于该疾病;与国内相比,国外创新影像学技术、深入病理分型、综合治疗、预后管理和多中心研究合作更多。多数研究以个案报道为主。结论手术治疗和影像诊断技术是原发心脏恶性肿瘤领域的研究焦点;基于病理分型和分子机制探讨改善患者预后的综合治疗可能是其未来发展趋势,基于多中心、多学科协作的高质量临床研究是重点。展开更多
文摘Cardiac primary tumors are uncommon with an estimated prevalence between 0.17%and 0.19%.[1,2]Cardiac lipoma are extremely rare representing only 10%?19%of primary cardiac tumors and only few are symptomatic,depending on their location within the heart.[3,4]They originate from the subendocardium(50%),subepicardium(25%)or myocardium(25%)and with different sizes and locations.[5]Few cases of sudden death due to primary cardiac tumors are reported in literature(0.0025%);in these cases,conductive and haemodinamic abnormalities have been indicated as the cause of death.
文摘Primary cardiac tumors are extremely uncommon.Here,we report the case of a patient with a primary left ventricular interstitial tumor presenting with hemodynamically unstable ventricular tachycardia.In response to hemodynamically unstable ventricular tachycardia,an implantable cardioverter-defibrillator was inserted.One month after defibrillator implantation,the patient developed episodes of high ventricular tachycardia that could not be effectively terminated by catheter radiofrequency ablation,thus further confirming that the ventricular tachycardia was induced by the left ventricular interstitial tumor.The patient is doing well on medical therapy to date.
文摘Objective: Through this surgical series, we present the epidemiological and anatomical-clinical aspects and the surgical results concerning patients operated on for a primary cardiac tumor at the Abidjan Heart Institute. Materials and Method: This is a retrospective descriptive study covering the period of January 1982 to December 2022, based on the medical records of patients operated on for a primary cardiac tumor at the Abidjan Heart Institute. Results: Twenty-seven (27) patients underwent surgery for a primary cardiac tumor, including 14 women and 13 men with a mean age of 41.5 years (range 19 - 76 years). The main circumstances of discovery were exertional dyspnea, palpitation and syncope or pseudo-syncope. The main site was the septal wall of the left atrium. The diagnosis of myxoma was confirmed by pathological examination of the surgical specimen in 96.3% (n = 24) of the patients and it was a malignant large cell immunoblastic lymphoma of the myocardium in 3.7% (n = 1) of the patients. The mean largest diameter was 46.1 mm. The postoperative course was marked by an ischaemic stroke (n = 1);recurrence of a left atrial myxoma 5 years after the first tumor removal (n = 1). Two cases of death were noted, one due to the evolution of immunoblastic large cell lymphoma and the other due to an extracorporeal circulation accident. Conclusion: Almost all primary cardiac tumors operated on in Abidjan are myxomas. The circumstances of the discovery of these cardiac tumors are multiple and varied but dominated by exertional dyspnea, palpitation and syncope. Whatever their histological type, primary cardiac tumors are serious affections, in view of the haemodynamic and rhythmic disorders they cause.
文摘Objective To analyze the experience of treatment strategies for pediatric patients with primary cardiac tumors. Methods The clinical data of 27 patients with primary cardiac tumors which detected by echocardiography from May 1999 to May 2009 was analyzed retrospectively. There were 20 male and 7 female patients,aged from 24 d to 12. 6 years. There were 59. 2% less than 1 year old at the time of diagnosis. A single tumor were present in 22 cases and multiple in 5 cases. Surgery was performed on 22 patients due to the varied
文摘<span style="font-family:""><span style="font-family:Verdana;">Primary cardiac lymphoma (PCL) is a rare entity that comprises only 1% - 2% of all cardiac tumors. Due to their scarcity and variable clinical presentation, early diagnosis is challenging. In this series, three cases of PCL from a single institution are described, which highlight the spectrum of presenting features and emphasize common principles. In the first case, a 73-year-old male who presented with dyspnea was found to have a 12.1 cm mass in the right ventricle. Biopsy via cardiac catheterization revealed diffuse large B cell ly</span><span style="font-family:Verdana;">mphoma (DLBCL). He was treated with chemoimmunotherapy and s</span><span style="font-family:Verdana;">urvived for two months. The second case describes a 55-year-old female who presented with chest pain. Imaging revealed a 3.1 cm right atrial mass and bilateral pleural effusions, with cytology from the latter demonstrating DLBCL. She was lost to follow up after three cycles of chemoimmunotherapy. In the last case, an 80-year-old female presented with weakness. A 4.0 cm mass was discovered in the right atrium and the patient expired shortly after admission. Autopsy confirmed the diagnosis of DLBCL. These case summaries are follo</span><span style="font-family:Verdana;">wed by a review of the clinical presentation, diagnostic approach, an</span><span style="font-family:Verdana;">d treatment outcomes of PCL.
