Aderived disaster is a commonconceptin natural emergencies, such as earthquakes. In recent years, the incidence of fractures caused by high-energy trauma has increased annually with socioeconomic development in China....Aderived disaster is a commonconceptin natural emergencies, such as earthquakes. In recent years, the incidence of fractures caused by high-energy trauma has increased annually with socioeconomic development in China.[1-3] Accordingly, derived injuries resulting from primary injuries have also been increasing considerably. However, most surgeons in the field of orthopedics and traumatology do not yet have adequate knowledge of such kind of derived injuries. We summarized our experience in managing a patient who experienced reinjury caused by a primary injury over the last decade and proposed the concept of a derived injury. In addition, we aimed to introduce a classification of derived injuries, explore their significance in orthopedic trauma, and discuss methods to minimize their severity.展开更多
The complex and variable nature of traumatic spinal cord inju- ry （SCI） presents a unique challenge for translational research. SCI is not bound by any demographic nor is it limited to specific injury biomechanics.
The ears are air-filled structures that are directly impacted during blast exposure.In addition to hearing loss and tinnitus,blast victims often complain of vertigo,dizziness and unsteady posture,suggesting that blast...The ears are air-filled structures that are directly impacted during blast exposure.In addition to hearing loss and tinnitus,blast victims often complain of vertigo,dizziness and unsteady posture,suggesting that blast exposure induces damage to the vestibular end organs in the inner ear.However,the underlying mechanisms remain to be elucidated.In this report,single vestibular afferent activity and the vestibuloocular reflex(VOR)were investigated before and after exposure to blast shock waves(~20 PSI)delivered into the left external ear canals of anesthetized rats.Single vestibular afferent activity was recorded from the superior branch of the left vestibular nerves of the blast-treated and control rats one day after blast exposure.Blast exposure reduced the spontaneous discharge rates of the otolith and canal afferents.Blast exposure also reduced the sensitivity of irregular canal afferents to sinusoidal head rotation at 0.5e2Hz.Blast exposure,however,resulted in few changes in the VOR responses to sinusoidal head rotation and translation.To the best of our knowledge,this is the first study that reports blast exposure-induced damage to vestibular afferents in an animal model.These results provide insights that may be helpful in developing biomarkers for early diagnosis of blast-induced vestibular deficits in military and civilian populations.展开更多
Background Intravascular volume expansion represents a beneficial measure against contrast-induced acute kidney injury （CI-AKI） in patients undergoing elective angiographic procedures. However, the efficacy of this ...Background Intravascular volume expansion represents a beneficial measure against contrast-induced acute kidney injury （CI-AKI） in patients undergoing elective angiographic procedures. However, the efficacy of this preventive strategy has not yet been established for patients with ST-elevation-myocardial infarction （STEMI）, who are at higher risk of this complication after primary percutaneous coronary intervention （PCI）. In this randomized study we investigated the possible beneficial role of periprocedural intravenous volume expansion and we compared the efficacy of 2 different hydration strategies in patients with STEMI undergoing primary PCI.展开更多
文摘Aderived disaster is a commonconceptin natural emergencies, such as earthquakes. In recent years, the incidence of fractures caused by high-energy trauma has increased annually with socioeconomic development in China.[1-3] Accordingly, derived injuries resulting from primary injuries have also been increasing considerably. However, most surgeons in the field of orthopedics and traumatology do not yet have adequate knowledge of such kind of derived injuries. We summarized our experience in managing a patient who experienced reinjury caused by a primary injury over the last decade and proposed the concept of a derived injury. In addition, we aimed to introduce a classification of derived injuries, explore their significance in orthopedic trauma, and discuss methods to minimize their severity.
文摘The complex and variable nature of traumatic spinal cord inju- ry （SCI） presents a unique challenge for translational research. SCI is not bound by any demographic nor is it limited to specific injury biomechanics.
文摘The ears are air-filled structures that are directly impacted during blast exposure.In addition to hearing loss and tinnitus,blast victims often complain of vertigo,dizziness and unsteady posture,suggesting that blast exposure induces damage to the vestibular end organs in the inner ear.However,the underlying mechanisms remain to be elucidated.In this report,single vestibular afferent activity and the vestibuloocular reflex(VOR)were investigated before and after exposure to blast shock waves(~20 PSI)delivered into the left external ear canals of anesthetized rats.Single vestibular afferent activity was recorded from the superior branch of the left vestibular nerves of the blast-treated and control rats one day after blast exposure.Blast exposure reduced the spontaneous discharge rates of the otolith and canal afferents.Blast exposure also reduced the sensitivity of irregular canal afferents to sinusoidal head rotation at 0.5e2Hz.Blast exposure,however,resulted in few changes in the VOR responses to sinusoidal head rotation and translation.To the best of our knowledge,this is the first study that reports blast exposure-induced damage to vestibular afferents in an animal model.These results provide insights that may be helpful in developing biomarkers for early diagnosis of blast-induced vestibular deficits in military and civilian populations.
文摘Background Intravascular volume expansion represents a beneficial measure against contrast-induced acute kidney injury （CI-AKI） in patients undergoing elective angiographic procedures. However, the efficacy of this preventive strategy has not yet been established for patients with ST-elevation-myocardial infarction （STEMI）, who are at higher risk of this complication after primary percutaneous coronary intervention （PCI）. In this randomized study we investigated the possible beneficial role of periprocedural intravenous volume expansion and we compared the efficacy of 2 different hydration strategies in patients with STEMI undergoing primary PCI.
