With the continuous promotion of the construction of child friendly cities,the school commuting space is an important component of the construction of child friendly roads.Based on the background of child friendly cit...With the continuous promotion of the construction of child friendly cities,the school commuting space is an important component of the construction of child friendly roads.Based on the background of child friendly cities,the commuting space of 11 primary and secondary schools in Bajiao Street is analyzed through literature analysis and field research methods.Firstly,the relevant literature on school commuting space is sorted out,and the characteristics of school commuting space are summarized,including transportation,landscape,culture,leisure,and security.Secondly,the characteristics of commuting space of primary and secondary schools in Bajiao Street are analyzed from three aspects:in front of the school gate,path space,and node space.This paper aims to provide reference and guidance for the future construction of children’s walking school commuting and promote the construction of a child friendly city.展开更多
As an important carrier of red culture,red music culture carries the glorious history of revolution,construction,and reform led by the Communist Party of China(CPC),and has significant functional value in cultivating ...As an important carrier of red culture,red music culture carries the glorious history of revolution,construction,and reform led by the Communist Party of China(CPC),and has significant functional value in cultivating students’ideals,values,and cultural identity,as well as patriotic consciousness and national pride.However,the integration of red music culture into the ideological and political education of primary and secondary schools faces the dilemmas of low cultivation awareness,insufficient excavation of resources,and lack of optimization of atmosphere and field.In view of these problems,the strategies of enhancing cultivation awareness,excavating the resources in-depth,and creating a positive atmosphere and field provide new ideas and methods for ideological and political education in primary and secondary schools.展开更多
Rule of law education in primary and secondary schools is an educational process to popularize legal knowledge,establish legal awareness,and cultivate the ability to respect,abide by,and use the law for the special gr...Rule of law education in primary and secondary schools is an educational process to popularize legal knowledge,establish legal awareness,and cultivate the ability to respect,abide by,and use the law for the special group of primary and secondary school students.The research found that rule of law education in primary and secondary schools in Chaoshan has yielded positive outcomes.However,there exist problems such as uneven synergy,incomplete inclusion of teachers and students,shortage of adequately trained professional teachers,and the need for enhanced organizational support.The relevance and effectiveness of rule of law education in primary and secondary schools will be enhanced by clarifying the target tasks,enhancing the effectiveness of the classroom,creating an atmosphere of the rule of law,and strengthening organizational support.展开更多
With the advent of the artificial intelligence(AI)era,there is a need to create a more flexible and humanistic educational ecosystem to adapt to the changes.Education needs to move from a unidirectional focus on skill...With the advent of the artificial intelligence(AI)era,there is a need to create a more flexible and humanistic educational ecosystem to adapt to the changes.Education needs to move from a unidirectional focus on skills to the cultivation of creative“whole people.”Due to the non-standardized evaluation system of the art discipline,its education has a unique advantage for the cultivation of students’creativity.At the same time,the interdisciplinary integration of fine arts points to the educational goals in the era of AI and the educational requirements for cultivating students’core qualities in China.Therefore,this paper analyzes the theoretical basis and developmental evolution of interdisciplinary integration,studies the significance of interdisciplinary integration in art education from the three levels of students,teaching,and disciplines,and explores four effective paths to realize interdisciplinary integration in art education in the era of AI.In this way,students can realize the contextualized analysis of knowledge,in-depth understanding of the content of the discipline,and accurate expression of the spiritual values embedded in art interdisciplinary learning.The ultimate goal is to cultivate students’ability to solve complex problems,promote the development of students’free personalities,and respond to the national education requirements.展开更多
With the vigorous development of social economy in China,various advanced technologies and equipment have emerged,among which artificial intelligence(AI)has rapidly developed and achieved remarkable results when appli...With the vigorous development of social economy in China,various advanced technologies and equipment have emerged,among which artificial intelligence(AI)has rapidly developed and achieved remarkable results when applied to many fields.Therefore,leaders and teachers in primary and secondary schools should pay more attention to AI education and explore effective measures to optimize the effectiveness of this education.Among them,carrying out artificial intelligence education and teaching from the perspective of thinking quality,with an aim to improve students’technical ability and effectively cultivate their thinking skills,may improve students’learning efficiency and teachers’teaching efficiency.How to carry out AI education from the perspective of thinking quality is an important issue that teachers need to address urgently.Through in-depth research,we focus on this issue,in hope to benefit primary and secondary school teachers.展开更多
The“burden reduction”policy aims to reduce the workload of primary and secondary school teachers to alleviate their burdens.While it has improved the quality of teachers,implementation challenges still exist.This st...The“burden reduction”policy aims to reduce the workload of primary and secondary school teachers to alleviate their burdens.While it has improved the quality of teachers,implementation challenges still exist.This study utilizes rational choice institutionalism and Ostrom’s institutional analysis and development framework to examine the policy.By considering the preferences of the Ministry of Education,local governments,schools,and teachers,it explores interactions and outcomes,identifies challenges,and provides policy suggestions.展开更多
[Objective] The aim was to provide certain theoretical basis for stuides on the high yield and high quality cultivation of Lycium barbarum L..[Method] Under yield conditions,the accumulation of primary substances and ...[Objective] The aim was to provide certain theoretical basis for stuides on the high yield and high quality cultivation of Lycium barbarum L..[Method] Under yield conditions,the accumulation of primary substances and secondary substances of Lycium barbarum L.was studied under different mulching treatments.[Result] Different mulching methods all had a certain effects on the contents of main primary substances and main secondary substances in Lycium barbarum L.fruit.Among them,carbohydrates and flavonoids contents in Lycium barbarum L.were both obviously increased under straw-film mulching;carotenoid content was decreased relatively;hundred leaf weight,1 000-grain weight and yield of Lycium barbarum L.were increased to a certain extent,but there was no obvious effect on the shape of fruit.Besides,the yield of Lycium barbarum L.had no significant positive correlation with total carbohydrate and polysaccharide,almost had no correlation with flavonoids,and had no significant negative correlation with carotenoid.[Conclusion] The reasonable mulching could improve the yield and quality of Lycium barbarum L..展开更多
A weakly nonlinear oscillator was modeled by a sort of differential equation, a saddle-node bifurcation was found in case of primary and secondary resonance. To control the jumping phenomena and the unstable region of...A weakly nonlinear oscillator was modeled by a sort of differential equation, a saddle-node bifurcation was found in case of primary and secondary resonance. To control the jumping phenomena and the unstable region of the nonlinear oscillator, feedback controllers were designed. Bifurcation control equations were obtained by using the multiple scales method. And through the numerical analysis, good controller could be obtained by changing the feedback control gain. Then a feasible way of further research of saddle-node bifurcation was provided. Finally, an example shows that the feedback control method applied to the hanging bridge system of gas turbine is doable.展开更多
Hyperoxaluria is characterized by an increased urinary excretion of oxalate. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria. Primary hyperoxaluria is an inherited error of m...Hyperoxaluria is characterized by an increased urinary excretion of oxalate. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria. Primary hyperoxaluria is an inherited error of metabolismdue to defective enzyme activity. In contrast, secondary hyperoxaluria is caused by increased dietary ingestion of oxalate, precursors of oxalate or alteration in intestinal microfora. The disease spectrum extends from recurrent kidney stones, nephrocalcinosis and urinary tract infections to chronic kidney disease and end stage renal disease. When calcium oxalate burden exceeds the renal excretory ability, calcium oxalate starts to deposit in various organ systems in a process called systemic oxalosis. Increased urinary oxalate levels help to make the diagnosis while plasma oxalate levels are likely to be more accurate when patients develop chronic kidney disease. Defnitivediagnosis of primary hyperoxaluria is achieved by genetic studies and if genetic studies prove inconclusive, liver biopsy is undertaken to establish diagnosis. Diagnostic clues pointing towards secondary hyperoxaluria are a supportive dietary history and tests to detect increased intestinal absorption of oxalate. Conservative treatment for both types of hyperoxaluria includes vigorous hydration and crystallization inhibitors to decrease calcium oxalate precipitation. Pyridoxine is also found to be helpful in approximately 30% patients with primary hyperoxaluriatype 1. Liver-kidney and isolated kidney transplantation are the treatment of choice in primary hyperoxaluria type 1 and type 2 respectively. Data is scarce on role of transplantation in primary hyperoxaluria type 3 where there are no reports of end stage renal disease so far. There are ongoing investigations into newer modalities of diagnosis and treatment of hyperoxaluria. Clinical differentiation between primary and secondary hyperoxaluria and further between the types of primary hyperoxaluria is very important because of implications in treatment and diagnosis. Hyperoxaluriacontinues to be a challenging disease and a high index of clinical suspicion is often the first step on the path to accurate diagnosis and management.展开更多
BACKGROUND: Hepatic lymphoma (HL) is categorized as primary and secondary hepatic lymphoma (PHL and SHL). This disorder can present as hepatic mass or mass-like lesion. Chemotherapy often is the first line treatm...BACKGROUND: Hepatic lymphoma (HL) is categorized as primary and secondary hepatic lymphoma (PHL and SHL). This disorder can present as hepatic mass or mass-like lesion. Chemotherapy often is the first line treatment for patients with HL. Thus, an accurate pre-management histological diagnosis is essential to potentially improve clinical outcomes. The present study was to explore the prevalence of HL in ultrasound guided liver biopsies for hepatic mass or mass-like lesions, to investigate HL associated clinicopathological features, to raise the awareness of early recognition and proper diagnosis of this entity, and to assess specimen adequacy in needle core biopsy. METHODS: Twenty-one cases of HL were enrolled. Clinical and pathological characteristics were evaluated, quality of biopsies was assessed and pertinent literature was reviewed. RESULTS: HL was diagnosed in 0.94% of 2242 liver biopsy cases with ambiguous clinical presentation, laboratory tests and image studies. There were two cases of PHL (0.09%), and nineteen cases of SHL (0.85%). Histopathologically, diffuse large B-cell lymphoma was the most common type, followed by B-cell lymphoma not otherwise specified, T-ceU lymphoma, Hodgkin's lymphoma, and B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma. Additionally, three lym- phocytic infiltration patterns were documented microscopically. The nodular infiltration was the most common type. CONCLUSIONS: HL is a rare entity and histopathology along with ancillary tests remains the only way to make the diagnosis.Clinicians' awareness of this entity and early liver biopsy are essential in patient management.展开更多
Geotechnical engineering that relates to the energy and environmental problem is receiving more and more attention worldwide.It is of great theoretical and practical value to study the properties of soil under thermal...Geotechnical engineering that relates to the energy and environmental problem is receiving more and more attention worldwide.It is of great theoretical and practical value to study the properties of soil under thermal mechanical coupling and its mathematical description.Firstly,based on the general function,a unified primary and secondary consolidation model of saturated soil considering heating temperature is deduced.Combining the existing research achievements,a practical model is obtained which comprehensively reflects the effective stress change,creep and heating effects.After that,a series of thermo-consolidation tests are carried out using a temperature controlled consolidation instrument to study the effects of effective stress,temperature and consolidation duration on saturated soils.The corresponding functional formulas and parameters are obtained thusly.On this basis,the calculation and analysis are carried out to check the reliability and applicability of the newly proposed model.The new model is simple and practical and the parameters are easy to be obtained.And it describes the main law of consolidation compression of saturated soils under the thermal mechanical coupling effect.Therefore,it is suggested for theoretical analysis of thermal geotechnical engineering problems.展开更多
Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries...Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries. Three-quarters of deaths due to cardiovascular diseases could be prevented with adequate changes in lifestyle, including increased daily physical activity. New evidence confirms that there is an inverse dose-response relationship between physical activity and cardiovascular disease and mortality risk. However, participation in moderate to vigorous physical activity may not fully attenuate the independent effect of sedentary activities on increased risk for cardiovascular diseases. Physical activity also plays an important role in secondary prevention of cardiovascular diseases by reducing the impact of the disease, slowing its progress and preventing recurrence. Nonetheless, most of eligible cardiovascular patients still do not benefit from secondary prevention/cardiac rehabilitation programs. The present review draws attention to the importance of physical activity in the primary and secondary prevention of cardiovascular diseases. It also addresses the mechanisms by which physical activity and regular exercise can improve cardiovascular health and reduce the burden of the disease.展开更多
To explore the impact of teacher training on the professional identity of primary and secondary school mental health teachers, this study conducted a half-month professional development training program to 54 primary ...To explore the impact of teacher training on the professional identity of primary and secondary school mental health teachers, this study conducted a half-month professional development training program to 54 primary and secondary school mental health teachers, and performed measurement on the professional identity of the teachers in the experimental group and the control group with “Teachers’ Professional Identity Questionnaire”. The result shows that after the training there is a significant improvement in the professional identity of the teachers in the experimental group, and the teachers’ scores on the four dimensions of profession identity: the sense of role, the professional behavioral tendency, the occupational values, and the sense of belonging, all increased significantly. This indicates that the curriculum intervention for the primary and secondary school mental health teachers could effectively improve the teachers’ professional identity.展开更多
The complex and variable nature of traumatic spinal cord inju- ry (SCI) presents a unique challenge for translational research. SCI is not bound by any demographic nor is it limited to specific injury biomechanics.
BACKGROUND Synovial sarcoma(SS)accounting for 6%-10%of primary soft tissue malignancies mainly occurs in deep soft tissue adjacent to joints of the limbs.Primary pulmonary SS(PPSS)is rare and has a poor prognosis.Case...BACKGROUND Synovial sarcoma(SS)accounting for 6%-10%of primary soft tissue malignancies mainly occurs in deep soft tissue adjacent to joints of the limbs.Primary pulmonary SS(PPSS)is rare and has a poor prognosis.Cases of secondary distant metastases of PPSS occur rarely and there is a lack of corresponding imaging reports.We summarized the imaging findings of PPSS with multiple metastases confirmed by surgery and pathology,and shared valuable information on PPSS.CASE SUMMARY A 43-year-old female patient had a solid space occupying lesion in the right upper lobe of the lung.The results of a hemogram,erythrocyte sedimentation rate(ESR)and tumor markers were all within the normal range,tuberculin skin test(5 TU PPD)was negative(-).Chest computed tomography examination showed similar round soft tissue density in the posterior segment of the right upper lobe.Thoracoscopic-assisted wedge resection of the right upper lobe of the lung,right upper lobe resection and lymph node dissection were performed.Nine months after surgery,ultrasound examination showed multiple metastases on the chest wall and kidney.CONCLUSION PPSS is a rare malignant lung tumor with strong invasiveness,early distant metastasis and poor prognosis.There are very few imaging reports.PPSS is often manifested as irregular tumor and calcification,and the metastases have extremely low echo on ultrasonography.Contrast-enhanced ultrasound indicates that the arterial phase of tumor metastases shows rapid centripetal high enhancement,manifested as“fast forward and fast regression”.展开更多
Primary dormancy of seeds of Korean pine(Pinus koraiensis Sieb.et Zucc.)after dispersal in the autumn and the induction of secondary dormancy the fi rst summer following seed dispersal limit the regeneration of mixed ...Primary dormancy of seeds of Korean pine(Pinus koraiensis Sieb.et Zucc.)after dispersal in the autumn and the induction of secondary dormancy the fi rst summer following seed dispersal limit the regeneration of mixed broadleaved Korean pine forests in Northeast China.This study was to determine how changes in the levels of abscisic acid(ABA)and gibberellic acid(GA)maintain primary and secondary dormancy of Korean pine seeds under germination conditions.We transferred seeds with one of fi ve primary dormancy states or three secondary dormancy states to germination conditions and measured changes in the levels of ABA,GA 1+3(GA 1 and GA 3)and GA 4+7(GA 4 and GA 7)in the seed coat,megagametophyte and embryo during incubation.Seed coat ABA levels in primary dormant seeds(PDS)and ABA levels in various parts of secondary dormant seeds(SDS)gradually declined during incubation but were still higher than in seeds for which dormancy was progressively released.GA 4+7 and GA 1+3 levels in embryos greatly decreased 35%and 24%,respectively,during incubation of SDS,and thus,the ratio of ABA to GA 4+7 in embryos and megagametophytes signifi cantly increased.The ratio of ABA to GA 1+3 in various parts of SDS increased slightly during incubation.In contrast,in seeds for which secondary dormancy was already released,GA 4+7 and GA 1+3 levels in the embryo,GA 4+7/ABA ratio in the embryo and seed coat,and the GA 1+3/ABA in the embryo and megagametophyte signifi cantly increased during incubation.There was no trend in the changes in the levels of ABA,GA 4+7 or GA 1+3 in embryos and megagametophytes of PDS or the levels of GA 4+7 or GA 1+3 in megagametophytes of SDS during incubation.The results suggest that high ABA levels in the seed coat maintain primary dormancy of Korean pine seeds.Maintenance of secondary dormancy involves a reduction of GA 4+7,GA 1+3,GA 4+7/ABA,and GA 1+3/ABA and the retention of high ABA levels.展开更多
The air-gap flux density formula and thrust expression of long primary double sided linear induction machine(DLIM)in the secondary motion reference frame are deduced by using the Maxwell equations firstly.Then,by anal...The air-gap flux density formula and thrust expression of long primary double sided linear induction machine(DLIM)in the secondary motion reference frame are deduced by using the Maxwell equations firstly.Then,by analyzing the factors that affect the thrust ripple in the thrust expression,a shuttle type secondary structure of long primary DLIMs is proposed,and its thrust performances of the machine with different shuttle size combinations are simulated and compared with that of plate secondary long primary DLIM.Comparison results show that the new secondary structure can suppress the thrust ripple and improve the stability of system acceleration.展开更多
AIM: To elucidate the effect of saliva stimulation by nizatidine on oral symptoms of primary biliary cirrhosis (PBC) by administering it to PBC cases. METHODS: From among 73 cases that had been definitively diagnosed ...AIM: To elucidate the effect of saliva stimulation by nizatidine on oral symptoms of primary biliary cirrhosis (PBC) by administering it to PBC cases. METHODS: From among 73 cases that had been definitively diagnosed as PBC at our hospital by February 2010, we selected 27 cases of PBC, 4 males and 23 females, as subjects. We obtained subjects' consent after giving them a full explanation of the administration of nizatidine. Nizatidine 150 mg was administered internally twice daily, after morning and evening meals. To observe changes in the quantity of saliva secreted, chewing gum tests were carried out four times: before the initial dose, and after 6 mo, 12 mo and 24 mo of administration. For subjective dry mouth symptoms, a visual analog scale (VAS) method was used to assess their feelings of oral dryness and eating difficulty, five times: before the initial dose, and after 1, 6, 12 and 24 mo of administration in 8 cases. The nutritional condition and the hepatic functional reserve were compared between before and after the nizatidine treatment.RESULTS: The result of a chewing gum test on the subjects before the administration of nizatidine showed that 50% produced less than 10 mL of saliva, i.e. , the standard under which cases are considered to have hyposalivation. The results of these tests showed that the quantity of saliva secreted was 10.5 ± 6.8 mL before administration of nizatidine, 10.9 ± 6.0 mL after 6 mo, 10.6 ± 4.9 mL after 12 mo, and 11.8 ± 6.8 mL after 24 mo administration. Thus, there was a slowly increasing trend in the quantity of saliva in the whole group. The percentage of subjects with saliva production above 10 mL was 45.8% after 6 mo administration of nizatidine, that is, only a slight change from before its administration, but it was 64.3% after 12 mo, that is, a significant increase. The saliva secretion by subject patients was examined before the beginning of administration of nizatidine, 12 mo later, and 24 mo later, and Fisher's combined probability test was used to examine the results for increases in saliva secretion. The analysis yielded P values of 0.51 and 0.53 for 12 mo later and 24 mo later, respectively. Thus, although there was no statistically significant increase, it was confirmed that saliva secretion tended to increase. A VAS method was employed to study the intensities of subjective symptoms of oral dryness and eating difficulty. Almost every case indicated some improvement of subjective oral dryness on the VAS early in the administration, i.e. , one month after. We also studied the effects of the administration of nizatidine on nutritional condition, hepatic functional reserve, and long-term prognosis of PBC. No significant improvements in cholinesterase (ChE) level, albumin (Alb) level, or Child-Pugh score were found during the period of observation from the beginning to the end of administration of nizatidine, nor in comparison with the non-administration group. A comparative analysis between before administration and 24 mo later yielded P values of 0.41 for Alb, 0.56 for ChE, and 0.59 for the Child-Pugh scores. CONCLUSION: It was confirmed that administering nizatidine to cases of PBC with dry mouth increased the secretion of saliva and improved the symptoms.展开更多
Introduction: Anemia and Ascaris infection are important indicators to reflect the health status of students. In this study, by investigating the current situation of low hemoglobin and positive rate of Ascaris eggs o...Introduction: Anemia and Ascaris infection are important indicators to reflect the health status of students. In this study, by investigating the current situation of low hemoglobin and positive rate of Ascaris eggs of primary and secondary school students in Hohhot, the health status of local primary and secondary school students is actually reflected. Objectives: To understand the prevalence of Low Hemoglobin and Ascaris infection among primary and secondary school students in Hohhot in 2015 and to give some suggestions on the health status of primary and secondary school students in Hohhot. Study Design: This project uses a cross-sectional study to investigate the distribution of disease and health status of primary and middle school students in Hohhot at a specific time, and to provide a clue to the cause of the hypothesis test. Methods: A stratified cluster random sampling method was used to select 4 districts, 4 counties and 1 flag in Hohhot, a total of 36 primary and secondary schools for sample survey. Cyanine HiCN and smear method is to detect hemoglobin and ascaris eggs positive. Results: In 2015, the positive rate of low hemoglobin in primary and secondary school students was 21.45% in urban and rural areas, 33.17% in urban and rural areas, 43.69% in rural areas, 13.59% in ascaris eggs, 10.69% in urban and rural areas, 7.81% in rural areas. There are geographical differences and gender differences between cities, urban-rural junctions and rural areas (p Conclusion: The prevalence of low hemoglobin in primary and secondary school students in Hohhot is high in rural areas. The detection rate of ascaris egg positive rate in the city is high. Monitoring, publicity and education should continue to be strengthened.展开更多
Introduction: Provoked vestibulodynia affects 12% of the general female population and more specifically, 21% of women aged less than 30 years. Primary and secondary vestibulodynia are hypothesized to represent the en...Introduction: Provoked vestibulodynia affects 12% of the general female population and more specifically, 21% of women aged less than 30 years. Primary and secondary vestibulodynia are hypothesized to represent the endpoints of different etiologic pathways, although there is still little research addressing potential distinctions between these two groups, particularly with regard to sexuality. Aims: To compare sexual activity and behavior of women with provoked primary vestibulodynia (PVD1) and secondary vestibulodynia (PVD2) against age-matched controls. Methods: Fifty-seven participants (N = 57), mean age 25.72 (18-41) recruited from a gynecology clinic underwent a gynaecological examination and completed a self-report questionnaire: 20 (N = 20) were diagnosed with primary provoked vestibulodynia (PVD1), 19 (N = 19) with secondary provoked vestibulodynia (PVD2), and 18 (N = 18) were medically confirmed as no-pain controls. Main outcome: To verify any differences in the sexual behavior between primary, secondary vestibulodynias and controls. Results: Mean pain duration differed significantly in participants with PVD1 at 73.8 months against those with PVD2 at 37.4 months (p = 0.003). Frequency of sexual activity also differed significantly between the three groups (p = 0.012): the controls were at 27.8% against 0% in primary and secondary vestibulodynias for once or more a day. No significant difference was observed for the sexual arousal time and masturbation frequency. Vaginal penetration was overrepresented in controls (p 0.001) contrary to fellatio frequency (p = 0.016). Pain digital test was significantly different between the three groups in one finger (3.85 vs 0.08), two fingers (4.39 vs 0.06) or three fingers (5.39 vs 0.56) (PVD1 against controls), lubricated inserted fingers for pain verification (p 0.001). Conclusions: Provoked vestibulodynia generates problems in the sexual response and coital activity, this syndrome reflecting absence of pre-existing sexual problems, notably in the masturbatory activity and oral receptive female sex.展开更多
基金National Natural Science Foundation of China(51708004)Beijing Youth Teaching Elite Team Construction Project(108051360023XN261)North China University of Technology Yuyou Talent Training Program(215051360020XN160/009).
文摘With the continuous promotion of the construction of child friendly cities,the school commuting space is an important component of the construction of child friendly roads.Based on the background of child friendly cities,the commuting space of 11 primary and secondary schools in Bajiao Street is analyzed through literature analysis and field research methods.Firstly,the relevant literature on school commuting space is sorted out,and the characteristics of school commuting space are summarized,including transportation,landscape,culture,leisure,and security.Secondly,the characteristics of commuting space of primary and secondary schools in Bajiao Street are analyzed from three aspects:in front of the school gate,path space,and node space.This paper aims to provide reference and guidance for the future construction of children’s walking school commuting and promote the construction of a child friendly city.
文摘As an important carrier of red culture,red music culture carries the glorious history of revolution,construction,and reform led by the Communist Party of China(CPC),and has significant functional value in cultivating students’ideals,values,and cultural identity,as well as patriotic consciousness and national pride.However,the integration of red music culture into the ideological and political education of primary and secondary schools faces the dilemmas of low cultivation awareness,insufficient excavation of resources,and lack of optimization of atmosphere and field.In view of these problems,the strategies of enhancing cultivation awareness,excavating the resources in-depth,and creating a positive atmosphere and field provide new ideas and methods for ideological and political education in primary and secondary schools.
文摘Rule of law education in primary and secondary schools is an educational process to popularize legal knowledge,establish legal awareness,and cultivate the ability to respect,abide by,and use the law for the special group of primary and secondary school students.The research found that rule of law education in primary and secondary schools in Chaoshan has yielded positive outcomes.However,there exist problems such as uneven synergy,incomplete inclusion of teachers and students,shortage of adequately trained professional teachers,and the need for enhanced organizational support.The relevance and effectiveness of rule of law education in primary and secondary schools will be enhanced by clarifying the target tasks,enhancing the effectiveness of the classroom,creating an atmosphere of the rule of law,and strengthening organizational support.
文摘With the advent of the artificial intelligence(AI)era,there is a need to create a more flexible and humanistic educational ecosystem to adapt to the changes.Education needs to move from a unidirectional focus on skills to the cultivation of creative“whole people.”Due to the non-standardized evaluation system of the art discipline,its education has a unique advantage for the cultivation of students’creativity.At the same time,the interdisciplinary integration of fine arts points to the educational goals in the era of AI and the educational requirements for cultivating students’core qualities in China.Therefore,this paper analyzes the theoretical basis and developmental evolution of interdisciplinary integration,studies the significance of interdisciplinary integration in art education from the three levels of students,teaching,and disciplines,and explores four effective paths to realize interdisciplinary integration in art education in the era of AI.In this way,students can realize the contextualized analysis of knowledge,in-depth understanding of the content of the discipline,and accurate expression of the spiritual values embedded in art interdisciplinary learning.The ultimate goal is to cultivate students’ability to solve complex problems,promote the development of students’free personalities,and respond to the national education requirements.
基金supported by the 2021 Guangdong Province General Universities Special Project in Key Areas(New Generation Information Technology)“Research on Building a Education Knowledge Graph Model for Higher Vocational Construction Major Supported by Artificial Intelligence”(Project No.2021ZDZX1112)the 2022 Higher Education Research Project of Guangdong Higher Education Association’s“14th Five Year Plan”“Research and Practice on the Cooperative Development Path of Higher Education in the Guangdong Hong Kong Macao Greater Bay Area from the Perspective of Supply Side Reform”(Project No.22GYB161).
文摘With the vigorous development of social economy in China,various advanced technologies and equipment have emerged,among which artificial intelligence(AI)has rapidly developed and achieved remarkable results when applied to many fields.Therefore,leaders and teachers in primary and secondary schools should pay more attention to AI education and explore effective measures to optimize the effectiveness of this education.Among them,carrying out artificial intelligence education and teaching from the perspective of thinking quality,with an aim to improve students’technical ability and effectively cultivate their thinking skills,may improve students’learning efficiency and teachers’teaching efficiency.How to carry out AI education from the perspective of thinking quality is an important issue that teachers need to address urgently.Through in-depth research,we focus on this issue,in hope to benefit primary and secondary school teachers.
文摘The“burden reduction”policy aims to reduce the workload of primary and secondary school teachers to alleviate their burdens.While it has improved the quality of teachers,implementation challenges still exist.This study utilizes rational choice institutionalism and Ostrom’s institutional analysis and development framework to examine the policy.By considering the preferences of the Ministry of Education,local governments,schools,and teachers,it explores interactions and outcomes,identifies challenges,and provides policy suggestions.
基金Supported by National Natural Science Foundation of China(30860227)Natural Science Foundation of Ningxia Province(NZ0603,NZ0639)~~
文摘[Objective] The aim was to provide certain theoretical basis for stuides on the high yield and high quality cultivation of Lycium barbarum L..[Method] Under yield conditions,the accumulation of primary substances and secondary substances of Lycium barbarum L.was studied under different mulching treatments.[Result] Different mulching methods all had a certain effects on the contents of main primary substances and main secondary substances in Lycium barbarum L.fruit.Among them,carbohydrates and flavonoids contents in Lycium barbarum L.were both obviously increased under straw-film mulching;carotenoid content was decreased relatively;hundred leaf weight,1 000-grain weight and yield of Lycium barbarum L.were increased to a certain extent,but there was no obvious effect on the shape of fruit.Besides,the yield of Lycium barbarum L.had no significant positive correlation with total carbohydrate and polysaccharide,almost had no correlation with flavonoids,and had no significant negative correlation with carotenoid.[Conclusion] The reasonable mulching could improve the yield and quality of Lycium barbarum L..
基金Project(10672053) supported by the National Natural Science Foundation of ChinaProject(2002AA503010) supported by the National High-Tech Research and Development Program of China
文摘A weakly nonlinear oscillator was modeled by a sort of differential equation, a saddle-node bifurcation was found in case of primary and secondary resonance. To control the jumping phenomena and the unstable region of the nonlinear oscillator, feedback controllers were designed. Bifurcation control equations were obtained by using the multiple scales method. And through the numerical analysis, good controller could be obtained by changing the feedback control gain. Then a feasible way of further research of saddle-node bifurcation was provided. Finally, an example shows that the feedback control method applied to the hanging bridge system of gas turbine is doable.
文摘Hyperoxaluria is characterized by an increased urinary excretion of oxalate. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria. Primary hyperoxaluria is an inherited error of metabolismdue to defective enzyme activity. In contrast, secondary hyperoxaluria is caused by increased dietary ingestion of oxalate, precursors of oxalate or alteration in intestinal microfora. The disease spectrum extends from recurrent kidney stones, nephrocalcinosis and urinary tract infections to chronic kidney disease and end stage renal disease. When calcium oxalate burden exceeds the renal excretory ability, calcium oxalate starts to deposit in various organ systems in a process called systemic oxalosis. Increased urinary oxalate levels help to make the diagnosis while plasma oxalate levels are likely to be more accurate when patients develop chronic kidney disease. Defnitivediagnosis of primary hyperoxaluria is achieved by genetic studies and if genetic studies prove inconclusive, liver biopsy is undertaken to establish diagnosis. Diagnostic clues pointing towards secondary hyperoxaluria are a supportive dietary history and tests to detect increased intestinal absorption of oxalate. Conservative treatment for both types of hyperoxaluria includes vigorous hydration and crystallization inhibitors to decrease calcium oxalate precipitation. Pyridoxine is also found to be helpful in approximately 30% patients with primary hyperoxaluriatype 1. Liver-kidney and isolated kidney transplantation are the treatment of choice in primary hyperoxaluria type 1 and type 2 respectively. Data is scarce on role of transplantation in primary hyperoxaluria type 3 where there are no reports of end stage renal disease so far. There are ongoing investigations into newer modalities of diagnosis and treatment of hyperoxaluria. Clinical differentiation between primary and secondary hyperoxaluria and further between the types of primary hyperoxaluria is very important because of implications in treatment and diagnosis. Hyperoxaluriacontinues to be a challenging disease and a high index of clinical suspicion is often the first step on the path to accurate diagnosis and management.
基金supported by a grant from the major research and development plan of the National Natural Science Foundation of China(91542205)
文摘BACKGROUND: Hepatic lymphoma (HL) is categorized as primary and secondary hepatic lymphoma (PHL and SHL). This disorder can present as hepatic mass or mass-like lesion. Chemotherapy often is the first line treatment for patients with HL. Thus, an accurate pre-management histological diagnosis is essential to potentially improve clinical outcomes. The present study was to explore the prevalence of HL in ultrasound guided liver biopsies for hepatic mass or mass-like lesions, to investigate HL associated clinicopathological features, to raise the awareness of early recognition and proper diagnosis of this entity, and to assess specimen adequacy in needle core biopsy. METHODS: Twenty-one cases of HL were enrolled. Clinical and pathological characteristics were evaluated, quality of biopsies was assessed and pertinent literature was reviewed. RESULTS: HL was diagnosed in 0.94% of 2242 liver biopsy cases with ambiguous clinical presentation, laboratory tests and image studies. There were two cases of PHL (0.09%), and nineteen cases of SHL (0.85%). Histopathologically, diffuse large B-cell lymphoma was the most common type, followed by B-cell lymphoma not otherwise specified, T-ceU lymphoma, Hodgkin's lymphoma, and B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma. Additionally, three lym- phocytic infiltration patterns were documented microscopically. The nodular infiltration was the most common type. CONCLUSIONS: HL is a rare entity and histopathology along with ancillary tests remains the only way to make the diagnosis.Clinicians' awareness of this entity and early liver biopsy are essential in patient management.
基金Project(51608281)supported by the National Natural Science Foundation of ChinaProject(LGG21E080005)supported by the Provincial Natural Science Foundation of Zhejiang Province,China。
文摘Geotechnical engineering that relates to the energy and environmental problem is receiving more and more attention worldwide.It is of great theoretical and practical value to study the properties of soil under thermal mechanical coupling and its mathematical description.Firstly,based on the general function,a unified primary and secondary consolidation model of saturated soil considering heating temperature is deduced.Combining the existing research achievements,a practical model is obtained which comprehensively reflects the effective stress change,creep and heating effects.After that,a series of thermo-consolidation tests are carried out using a temperature controlled consolidation instrument to study the effects of effective stress,temperature and consolidation duration on saturated soils.The corresponding functional formulas and parameters are obtained thusly.On this basis,the calculation and analysis are carried out to check the reliability and applicability of the newly proposed model.The new model is simple and practical and the parameters are easy to be obtained.And it describes the main law of consolidation compression of saturated soils under the thermal mechanical coupling effect.Therefore,it is suggested for theoretical analysis of thermal geotechnical engineering problems.
基金supported by the Portuguese Foundation for Science and Technology,(UID/DTP/04045/2013)by the European Regional Develop-ment Fund,through COMPETE 2020(POCI--01--0145-FEDER--006969)+4 种基金funded by the European Regional Development Fund,through NORTE 2020(NORTE--01--0145--FEDER--000016)The European Regional Development Fund through the Operational Competitiveness Programthe Foun-dation for Science and Technology(FCT)of Portugal support the research unit CIAFEL within the projects FCOMP--01--0124--FEDER--020180(References FCT:PTDC/DES/122763/2010)and UID/DTP/00617/2013supported by the Portuguese Foundation for Science and Technology(REF:UID/BIM/04501/2013)FEDER/Compete2020 funds
文摘Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries. Three-quarters of deaths due to cardiovascular diseases could be prevented with adequate changes in lifestyle, including increased daily physical activity. New evidence confirms that there is an inverse dose-response relationship between physical activity and cardiovascular disease and mortality risk. However, participation in moderate to vigorous physical activity may not fully attenuate the independent effect of sedentary activities on increased risk for cardiovascular diseases. Physical activity also plays an important role in secondary prevention of cardiovascular diseases by reducing the impact of the disease, slowing its progress and preventing recurrence. Nonetheless, most of eligible cardiovascular patients still do not benefit from secondary prevention/cardiac rehabilitation programs. The present review draws attention to the importance of physical activity in the primary and secondary prevention of cardiovascular diseases. It also addresses the mechanisms by which physical activity and regular exercise can improve cardiovascular health and reduce the burden of the disease.
文摘To explore the impact of teacher training on the professional identity of primary and secondary school mental health teachers, this study conducted a half-month professional development training program to 54 primary and secondary school mental health teachers, and performed measurement on the professional identity of the teachers in the experimental group and the control group with “Teachers’ Professional Identity Questionnaire”. The result shows that after the training there is a significant improvement in the professional identity of the teachers in the experimental group, and the teachers’ scores on the four dimensions of profession identity: the sense of role, the professional behavioral tendency, the occupational values, and the sense of belonging, all increased significantly. This indicates that the curriculum intervention for the primary and secondary school mental health teachers could effectively improve the teachers’ professional identity.
文摘The complex and variable nature of traumatic spinal cord inju- ry (SCI) presents a unique challenge for translational research. SCI is not bound by any demographic nor is it limited to specific injury biomechanics.
文摘BACKGROUND Synovial sarcoma(SS)accounting for 6%-10%of primary soft tissue malignancies mainly occurs in deep soft tissue adjacent to joints of the limbs.Primary pulmonary SS(PPSS)is rare and has a poor prognosis.Cases of secondary distant metastases of PPSS occur rarely and there is a lack of corresponding imaging reports.We summarized the imaging findings of PPSS with multiple metastases confirmed by surgery and pathology,and shared valuable information on PPSS.CASE SUMMARY A 43-year-old female patient had a solid space occupying lesion in the right upper lobe of the lung.The results of a hemogram,erythrocyte sedimentation rate(ESR)and tumor markers were all within the normal range,tuberculin skin test(5 TU PPD)was negative(-).Chest computed tomography examination showed similar round soft tissue density in the posterior segment of the right upper lobe.Thoracoscopic-assisted wedge resection of the right upper lobe of the lung,right upper lobe resection and lymph node dissection were performed.Nine months after surgery,ultrasound examination showed multiple metastases on the chest wall and kidney.CONCLUSION PPSS is a rare malignant lung tumor with strong invasiveness,early distant metastasis and poor prognosis.There are very few imaging reports.PPSS is often manifested as irregular tumor and calcification,and the metastases have extremely low echo on ultrasonography.Contrast-enhanced ultrasound indicates that the arterial phase of tumor metastases shows rapid centripetal high enhancement,manifested as“fast forward and fast regression”.
基金We thank Kai Yang and Lizhong Yu and Xiao Zheng and Tao Sun for valuable discussion and suggestions about this study.We also thank Hongjun Xu,Jingpu Zhang,Weiwei Zhang and Shuang Xu for fi eld support and technical assistance.
文摘Primary dormancy of seeds of Korean pine(Pinus koraiensis Sieb.et Zucc.)after dispersal in the autumn and the induction of secondary dormancy the fi rst summer following seed dispersal limit the regeneration of mixed broadleaved Korean pine forests in Northeast China.This study was to determine how changes in the levels of abscisic acid(ABA)and gibberellic acid(GA)maintain primary and secondary dormancy of Korean pine seeds under germination conditions.We transferred seeds with one of fi ve primary dormancy states or three secondary dormancy states to germination conditions and measured changes in the levels of ABA,GA 1+3(GA 1 and GA 3)and GA 4+7(GA 4 and GA 7)in the seed coat,megagametophyte and embryo during incubation.Seed coat ABA levels in primary dormant seeds(PDS)and ABA levels in various parts of secondary dormant seeds(SDS)gradually declined during incubation but were still higher than in seeds for which dormancy was progressively released.GA 4+7 and GA 1+3 levels in embryos greatly decreased 35%and 24%,respectively,during incubation of SDS,and thus,the ratio of ABA to GA 4+7 in embryos and megagametophytes signifi cantly increased.The ratio of ABA to GA 1+3 in various parts of SDS increased slightly during incubation.In contrast,in seeds for which secondary dormancy was already released,GA 4+7 and GA 1+3 levels in the embryo,GA 4+7/ABA ratio in the embryo and seed coat,and the GA 1+3/ABA in the embryo and megagametophyte signifi cantly increased during incubation.There was no trend in the changes in the levels of ABA,GA 4+7 or GA 1+3 in embryos and megagametophytes of PDS or the levels of GA 4+7 or GA 1+3 in megagametophytes of SDS during incubation.The results suggest that high ABA levels in the seed coat maintain primary dormancy of Korean pine seeds.Maintenance of secondary dormancy involves a reduction of GA 4+7,GA 1+3,GA 4+7/ABA,and GA 1+3/ABA and the retention of high ABA levels.
基金supported by the Research Project of Electromagnetic Simulation Research and Development of Induction Motor of Beijing Jiaotong University (No.E18L00100)
文摘The air-gap flux density formula and thrust expression of long primary double sided linear induction machine(DLIM)in the secondary motion reference frame are deduced by using the Maxwell equations firstly.Then,by analyzing the factors that affect the thrust ripple in the thrust expression,a shuttle type secondary structure of long primary DLIMs is proposed,and its thrust performances of the machine with different shuttle size combinations are simulated and compared with that of plate secondary long primary DLIM.Comparison results show that the new secondary structure can suppress the thrust ripple and improve the stability of system acceleration.
文摘AIM: To elucidate the effect of saliva stimulation by nizatidine on oral symptoms of primary biliary cirrhosis (PBC) by administering it to PBC cases. METHODS: From among 73 cases that had been definitively diagnosed as PBC at our hospital by February 2010, we selected 27 cases of PBC, 4 males and 23 females, as subjects. We obtained subjects' consent after giving them a full explanation of the administration of nizatidine. Nizatidine 150 mg was administered internally twice daily, after morning and evening meals. To observe changes in the quantity of saliva secreted, chewing gum tests were carried out four times: before the initial dose, and after 6 mo, 12 mo and 24 mo of administration. For subjective dry mouth symptoms, a visual analog scale (VAS) method was used to assess their feelings of oral dryness and eating difficulty, five times: before the initial dose, and after 1, 6, 12 and 24 mo of administration in 8 cases. The nutritional condition and the hepatic functional reserve were compared between before and after the nizatidine treatment.RESULTS: The result of a chewing gum test on the subjects before the administration of nizatidine showed that 50% produced less than 10 mL of saliva, i.e. , the standard under which cases are considered to have hyposalivation. The results of these tests showed that the quantity of saliva secreted was 10.5 ± 6.8 mL before administration of nizatidine, 10.9 ± 6.0 mL after 6 mo, 10.6 ± 4.9 mL after 12 mo, and 11.8 ± 6.8 mL after 24 mo administration. Thus, there was a slowly increasing trend in the quantity of saliva in the whole group. The percentage of subjects with saliva production above 10 mL was 45.8% after 6 mo administration of nizatidine, that is, only a slight change from before its administration, but it was 64.3% after 12 mo, that is, a significant increase. The saliva secretion by subject patients was examined before the beginning of administration of nizatidine, 12 mo later, and 24 mo later, and Fisher's combined probability test was used to examine the results for increases in saliva secretion. The analysis yielded P values of 0.51 and 0.53 for 12 mo later and 24 mo later, respectively. Thus, although there was no statistically significant increase, it was confirmed that saliva secretion tended to increase. A VAS method was employed to study the intensities of subjective symptoms of oral dryness and eating difficulty. Almost every case indicated some improvement of subjective oral dryness on the VAS early in the administration, i.e. , one month after. We also studied the effects of the administration of nizatidine on nutritional condition, hepatic functional reserve, and long-term prognosis of PBC. No significant improvements in cholinesterase (ChE) level, albumin (Alb) level, or Child-Pugh score were found during the period of observation from the beginning to the end of administration of nizatidine, nor in comparison with the non-administration group. A comparative analysis between before administration and 24 mo later yielded P values of 0.41 for Alb, 0.56 for ChE, and 0.59 for the Child-Pugh scores. CONCLUSION: It was confirmed that administering nizatidine to cases of PBC with dry mouth increased the secretion of saliva and improved the symptoms.
文摘Introduction: Anemia and Ascaris infection are important indicators to reflect the health status of students. In this study, by investigating the current situation of low hemoglobin and positive rate of Ascaris eggs of primary and secondary school students in Hohhot, the health status of local primary and secondary school students is actually reflected. Objectives: To understand the prevalence of Low Hemoglobin and Ascaris infection among primary and secondary school students in Hohhot in 2015 and to give some suggestions on the health status of primary and secondary school students in Hohhot. Study Design: This project uses a cross-sectional study to investigate the distribution of disease and health status of primary and middle school students in Hohhot at a specific time, and to provide a clue to the cause of the hypothesis test. Methods: A stratified cluster random sampling method was used to select 4 districts, 4 counties and 1 flag in Hohhot, a total of 36 primary and secondary schools for sample survey. Cyanine HiCN and smear method is to detect hemoglobin and ascaris eggs positive. Results: In 2015, the positive rate of low hemoglobin in primary and secondary school students was 21.45% in urban and rural areas, 33.17% in urban and rural areas, 43.69% in rural areas, 13.59% in ascaris eggs, 10.69% in urban and rural areas, 7.81% in rural areas. There are geographical differences and gender differences between cities, urban-rural junctions and rural areas (p Conclusion: The prevalence of low hemoglobin in primary and secondary school students in Hohhot is high in rural areas. The detection rate of ascaris egg positive rate in the city is high. Monitoring, publicity and education should continue to be strengthened.
文摘Introduction: Provoked vestibulodynia affects 12% of the general female population and more specifically, 21% of women aged less than 30 years. Primary and secondary vestibulodynia are hypothesized to represent the endpoints of different etiologic pathways, although there is still little research addressing potential distinctions between these two groups, particularly with regard to sexuality. Aims: To compare sexual activity and behavior of women with provoked primary vestibulodynia (PVD1) and secondary vestibulodynia (PVD2) against age-matched controls. Methods: Fifty-seven participants (N = 57), mean age 25.72 (18-41) recruited from a gynecology clinic underwent a gynaecological examination and completed a self-report questionnaire: 20 (N = 20) were diagnosed with primary provoked vestibulodynia (PVD1), 19 (N = 19) with secondary provoked vestibulodynia (PVD2), and 18 (N = 18) were medically confirmed as no-pain controls. Main outcome: To verify any differences in the sexual behavior between primary, secondary vestibulodynias and controls. Results: Mean pain duration differed significantly in participants with PVD1 at 73.8 months against those with PVD2 at 37.4 months (p = 0.003). Frequency of sexual activity also differed significantly between the three groups (p = 0.012): the controls were at 27.8% against 0% in primary and secondary vestibulodynias for once or more a day. No significant difference was observed for the sexual arousal time and masturbation frequency. Vaginal penetration was overrepresented in controls (p 0.001) contrary to fellatio frequency (p = 0.016). Pain digital test was significantly different between the three groups in one finger (3.85 vs 0.08), two fingers (4.39 vs 0.06) or three fingers (5.39 vs 0.56) (PVD1 against controls), lubricated inserted fingers for pain verification (p 0.001). Conclusions: Provoked vestibulodynia generates problems in the sexual response and coital activity, this syndrome reflecting absence of pre-existing sexual problems, notably in the masturbatory activity and oral receptive female sex.