部分型房室间隔缺损的外科治疗

目的:总结60例部分型房室间隔缺损的外科治疗经验。方法:回顾性分析经手术治疗的60例部分型房室间隔缺损患者的临床资料。二尖瓣前瓣分裂的处理,58例缝合二尖瓣裂隙,2例行机械二尖瓣置换;原发孔房间隔缺损的修补,53例采用心包片,7例采用绦纶补片;35例采用Kirklin法将冠状静脉窦口隔入左房,25例采用McGoon法将冠状静脉窦口隔入右房;同期处理合并的畸形。结果:共死亡2例,均死于低心排出量综合征,死亡率3.3%(2/60);采用Kirklin法和McGoon法手术的患者术后完全性房室传导阻滞发生率分别为8.00%(2/35),6.06%(2/25),2组比较差异无统计学意义(P>0.05);随访1月至5年,无晚期死亡,除1例3个月后复查出现二尖瓣中度返流外,余患者未出现轻度以上二尖瓣和/或三尖瓣狭窄或关闭不全,心功能均得到不同程度改善。结论:针对部分型房室间隔缺损患者,合理的手术设计、术中细致操作、避免损伤传导组织以及加强围手术期管理均可取得的良好的近、中期疗效。

阿司匹林和复方新诺明对大豆种子萌发及活力的影响

以大豆(Glycine max)种子为材料,用不同浓度的阿斯匹林和复方新诺明水溶液,在(20±1)℃条件下分别浸种24 h和12 h,测定大豆种子萌发过程中的各项生理生化指标以及萌发后的各形态指标。实验结果表明:阿斯匹林和复方新诺明水溶液浸种都能有效地提高大豆种子的发芽率和活力指数,还能促进大豆根系的生长。其中以62.5 nlg·L-1的阿斯匹林和0.5 mg·L-1的复方新诺明处理后的效果最为显著。阿斯匹林浸种能使大豆萌芽的相对电导率显著降低,使活性氧清除酶的活性有所提高。复方新诺明浸种则使大豆萌芽的蛋白质含量以及氨基酸总量都有显著的提高。

110例部分房室管畸形的手术治疗经验

目的部分房室管畸形是一种较少见的复杂先天性心脏病。文中分析110例部分房室管畸形的手术治疗方法,为提高临床治疗效果提供借鉴。方法对110例部分房室管畸形的临床资料进行回顾性分析。对二尖瓣大瓣裂的处理,108例采用单纯瓣裂缝合,其中另行瓣环成形6例,加瓣叶、乳头肌或腱索成形各3例,机械瓣置换2例;原发孔房间隔缺损均以自体心包补片修补,57例采用Kirklin法、53例采用McGoon法;同时纠治三尖瓣关闭不全及其他合并畸形。结果术后早期死亡3例,病死率2.7%。发生Ⅲ度传导阻滞2例,Kirklin法、McGoon法各1例,组间比较差异无统计学意义（P〉0.05）。99例随访0.5~20年,无远期死亡,复查心脏超声二尖瓣关闭不全完全纠正70例,残留轻度关闭不全26例,仍有中度关闭不全3例,心功能均得到明显改善。结论早期手术矫治部分房室管畸形可取得满意疗效,合理的手术设计、尽可能消除二尖瓣返流及避免损伤传导组织是手术成功的关键。

复方新诺明对甜瓜种子萌发及活力的影响

以甜瓜种子为试材,通过SMZ-TMP预处理,研究了SMZ-TMP对甜瓜种子萌发质量及相关生理特性的作用。结果表明:较低浓度预处理明显促进了甜瓜种子萌发和生长,其萌发指数、发芽势、发芽率、根冠比和生物学产量等指标呈显著增长趋势,其中以0.4mg/L处理的效果极为显著。不同浓度的SMZ-TMP溶液均可降低甜瓜的相对电导率和MDA含量,但相对电导率和MDA含量的下降幅度随SMZ-TMP浓度的增加而减少。SMZ-TMP浸种使甜瓜萌芽的蛋白质和氨基酸总量都有显著提高。

Extending Electromagnetic Treatment to Infectious Diseases including the Ebola Virus

A blueprint for research and development for design and development of suitable electromagnetic treatment of genetic diseases (Escultura, Journal of Biomaterials and Nanobiotechnology, 3(2), 2012) known as genetic sterilization is applied to infectious diseases including viruses. It is based on the Grand Unified Theory (Escultura, Nonlinear Analysis, A-Series, 69(3), 2008) and the Unified Theory of Evolution (Escultura, The Journal of the Science of Healing Outcomes, 2015). Since every physical characteristic of living thing is determined by a gene, so is the undesirable symptom of a disease. For virus, its undesirable symptom is determined principally by the wavelength of the natural vibration of its gene as sequence of base materials which is equal to its measure as a segment of a double helix. Radiation with wavelength equal to this measure will resonate with it. Raising its intensity suitably will sterilize the gene, stop its spread and render it harmless to the host;then the disease is treated without harm to normal cells. Another treatment is establishing resonance with radiation of wavelength equal to the measure of the virus (protein strand with the gene) across;raising its intensity suitably will burn the virus without side effect (since it is much smaller than normal cells).

Electromagnetic Treatment of Genetic Diseases

The paper offers an overview of quantum and macro gravity, two of the three pillars of the Grand Unified Theory (GUT), the other thermodynamics, developed in a series of papers since the solution of the gravitational n-body problem in 1997 (J. Nonlinear Analysis, A-Series: Theory, Methods and Applications, Vol. 30, No. 8, 1997, pp. 5021 - 5032) and consolidated in the paper, The Grand Unified Theory (J. Nonlinear Analysis, A-Series: Theory: Method and Applications, Vol. 69, No. 3, 2008, pp. 823 - 831). GUT is further advanced by the paper, The Mathematics of GUT (J. Nonlinear Analysis, A-Series: Theory: Method and Applications, Vol. 71, 2009, pp. e420 - e431) and the discovery of more natural laws in the course of analyzing and explaining the disastrous final flight of the Columbia Space Shuttle in 2004 (J. Nonlinear Studies, Vol. 14, No. 3, 2007, pp. 241 - 260). Qualitative modeling was the key to the development of GUT and its theoretical and practical applications. The relevant natural laws of GUT that provide the foundations of the Unified Theory of Evolution are stated. GUT provides the basis for the development of the electromagnetic engine and the Unified Theory of Evolution, its theoretical application, for the development of appropriate technology for electromagnetic treatment of genetic diseases such as cancer, systemic lupos erythematosus, diabetes, muscular dystrophy and mental disorder, the central focus of this paper.

Is Human Activity Linked to Climate Change?

This paper establishes the link between human activity and climate change, e.g., more frequent and devastating typhoons, tornadoes, bushfires, droughts, floods and snowstorms and melting of the norther polar ice cap and recent occurrences of super typhoons and tornadoes. Qualitative mathematics and modeling(QMAM) explains this link and its remarkable verification based on the grand unified theory(GUT).

The Logic and Fundamental Concepts of the Grand Unified Theory

The grand unified theory (GUT) originated in mathematics with this question: why are there long standing unsolved problems in mathematics, e.g., Fermat’s conjecture (also known as Fermat’s last theorem (FLT))? The answer came quickly: its underlying fields—foundations and the real number system—are defective. In particular, formal logic is inapplicable to mathematics (language of science) and the real number system is inconsistent. Critique-rectification of these fields was undertaken leading to a new mathematical methodology and the consistent new real number system that provides the main mathematics of GUT. Similar question was posed in physics: why are there long standing problems, e.g., the gravitational n-body and turbulence problems? The answer: the present methodology, quantitative modeling is inadequate and the remedy is a new methodology—qualitative mathematics and modeling that solved these problems and provided the initial formulation of GUT. This paper presents the basic logic of GUT and its fundamental concepts, particularly, the superstring or fundamental building block of matter.

儿童原发隔异位型肺静脉异位引流的超声心动图诊断

目的探讨超声心动图对原发隔异位(malposition of septum primum,MSP)型肺静脉异位引流的诊断价值。方法回顾分析7名MSP儿童的超声心动图征象,并于CTA和胸外科直视手术结果比较。结果6例(85.7%)超声诊断正确,1例误诊为单心房。1例合并部分性肺静脉异位引流,6例合并完全性肺静脉异位引流。超声心动图显示所有肺静脉均开口于解剖左房后壁,因原发隔异位导致肺静脉异常引流入右房。剑突下冠状、剑突下矢状、心尖四腔、胸骨旁短轴切面可清晰显示继发隔上边缘带缺如以及原发隔不同程度左移。结论超声心动图作为一种非创伤性的检查手段,能正确诊断原发隔异位,为该病的进一步诊断与治疗提供更多信息。

交感神经颈下节的定位研究

在３０例成人尸体上对交感神经颈下节的位置、形态、大小及与周围主要标志的关系进行了研究，根据研究结果，提出了经皮进行交感神经颈下节进行阻滞时的具体位置及步骤，为临床工作提出了形态学依据。

先天性原发隔异位型肺静脉异位引流的超声心动图诊断

目的分析原发隔异位(MSP)型肺静脉异位引流(APVC)的超声心动图诊断特点,以期为临床手术提供更多的信息。方法回顾性收集2015年1月至2022年4月在浙江大学医学院附属儿童医院经心脏外科手术或CTA证实的21例MSP型APVC患儿的临床资料及超声心动图表现,分析纳入患儿的一般资料、合并畸形、超声心动图特征、误诊情况及外科手术和随访情况。结果21例MSP型APVC患儿中完全性肺静脉异位引流(TAPVC)8例、部分性肺静脉异位引流(PAPVC)13例;1例合并多脾综合征。超声心动图表现为肺静脉均开口于解剖左心房的后壁,继发隔发育不良或缺失,原发隔不同程度的偏移导致部分或全部的肺静脉血液引流至解剖右心房。超声首诊正确诊断18例(18/21,85.7%),误诊3例,分别为:1例MSP型TAPVC误诊为三房心合并PAPVC,1例MSP型PAPVC误诊为TAPVC合并继发孔房间隔缺损(ASD),1例MSP型PAPVC误诊为继发孔ASD。20例患儿经心脏外科手术治疗,术后随访4~69个月(平均34个月),所有患儿均预后良好。结论超声心动图能正确诊断MSP型APVC及其合并的心内畸形,有助于手术方式的合理选择,提高手术治疗成功率。

先天性原发隔异位的多普勒超声心动图诊断

目的分析先天性原发隔异位(malposition of septum primum,MSP)的多普勒超声心动图特征,评价多普勒超声心动图对MSP的诊断价值,分析超声心动图漏误诊的原因,提高超声心动图对MSP诊断的准确性。方法回顾性分析2009年1月至2019年10月在上海交通大学医学院附属新华医院及上海交通大学医学院附属上海儿童医学中心8例经CTA、心外科手术或尸体解剖诊断为MSP患儿的超声心动图检查资料。结果超声心动图显示肺静脉开口于解剖左房后壁,继发隔上边缘带缺如,原发隔向左偏移,肺静脉异常引流入原发隔右侧的心房。本组7例合并完全性肺静脉异位引流,1例合并部分性肺静脉异位引流。8例患儿中超声诊断正确6例;超声误诊2例,其中1例误诊为单心房,1例误诊为三房心。结论超声心动图技术可以准确地诊断MSP,但需与单心房、三房心等畸形鉴别。