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On the Method of Solution for the Non-Homogeneous Generalized Riemann-Hilbert Boundary Value Problems
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作者 ZHANG Wen-wen LI Ping-run 《Chinese Quarterly Journal of Mathematics》 2024年第3期262-269,共8页
This paper studies the non-homogeneous generalized Riemann-Hilbert(RH)problems involving two unknown functions.Using the uniformization theorem,such problems are transformed into the case of homogeneous type.By the th... This paper studies the non-homogeneous generalized Riemann-Hilbert(RH)problems involving two unknown functions.Using the uniformization theorem,such problems are transformed into the case of homogeneous type.By the theory of classical boundary value problems,we adopt a novel method to obtain the sectionally analytic solutions of problems in strip domains,and analyze the conditions of solvability and properties of solutions in various domains. 展开更多
关键词 Generalized Riemann-Hilbert problem Uniformization theorem Analytic solution Sokhotski-Plemelj formula
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A Novel Insertion Solution for the Travelling Salesman Problem
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作者 Emmanuel Oluwatobi Asani Aderemi Elisha Okeyinka +5 位作者 Sunday Adeola Ajagbe Ayodele Ariyo Adebiyi Roseline Oluwaseun Ogundokun Temitope Samson Adekunle Pragasen Mudali Matthew Olusegun Adigun 《Computers, Materials & Continua》 SCIE EI 2024年第4期1581-1597,共17页
The studypresents theHalfMax InsertionHeuristic (HMIH) as a novel approach to solving theTravelling SalesmanProblem (TSP). The goal is to outperform existing techniques such as the Farthest Insertion Heuristic (FIH) a... The studypresents theHalfMax InsertionHeuristic (HMIH) as a novel approach to solving theTravelling SalesmanProblem (TSP). The goal is to outperform existing techniques such as the Farthest Insertion Heuristic (FIH) andNearest Neighbour Heuristic (NNH). The paper discusses the limitations of current construction tour heuristics,focusing particularly on the significant margin of error in FIH. It then proposes HMIH as an alternative thatminimizes the increase in tour distance and includes more nodes. HMIH improves tour quality by starting withan initial tour consisting of a ‘minimum’ polygon and iteratively adding nodes using our novel Half Max routine.The paper thoroughly examines and compares HMIH with FIH and NNH via rigorous testing on standard TSPbenchmarks. The results indicate that HMIH consistently delivers superior performance, particularly with respectto tour cost and computational efficiency. HMIH’s tours were sometimes 16% shorter than those generated by FIHand NNH, showcasing its potential and value as a novel benchmark for TSP solutions. The study used statisticalmethods, including Friedman’s Non-parametric Test, to validate the performance of HMIH over FIH and NNH.This guarantees that the identified advantages are statistically significant and consistent in various situations. Thiscomprehensive analysis emphasizes the reliability and efficiency of the heuristic, making a compelling case for itsuse in solving TSP issues. The research shows that, in general, HMIH fared better than FIH in all cases studied,except for a few instances (pr439, eil51, and eil101) where FIH either performed equally or slightly better thanHMIH. HMIH’s efficiency is shown by its improvements in error percentage (δ) and goodness values (g) comparedto FIH and NNH. In the att48 instance, HMIH had an error rate of 6.3%, whereas FIH had 14.6% and NNH had20.9%, indicating that HMIH was closer to the optimal solution. HMIH consistently showed superior performanceacross many benchmarks, with lower percentage error and higher goodness values, suggesting a closer match tothe optimal tour costs. This study substantially contributes to combinatorial optimization by enhancing currentinsertion algorithms and presenting a more efficient solution for the Travelling Salesman Problem. It also createsnew possibilities for progress in heuristic design and optimization methodologies. 展开更多
关键词 Nearest neighbour heuristic farthest insertion heuristic half max insertion heuristic tour construction travelling salesman problem
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Wavelet Multi-Resolution Interpolation Galerkin Method for Linear Singularly Perturbed Boundary Value Problems
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作者 Jiaqun Wang Guanxu Pan +1 位作者 Youhe Zhou Xiaojing Liu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期297-318,共22页
In this study,a wavelet multi-resolution interpolation Galerkin method(WMIGM)is proposed to solve linear singularly perturbed boundary value problems.Unlike conventional wavelet schemes,the proposed algorithm can be r... In this study,a wavelet multi-resolution interpolation Galerkin method(WMIGM)is proposed to solve linear singularly perturbed boundary value problems.Unlike conventional wavelet schemes,the proposed algorithm can be readily extended to special node generation techniques,such as the Shishkin node.Such a wavelet method allows a high degree of local refinement of the nodal distribution to efficiently capture localized steep gradients.All the shape functions possess the Kronecker delta property,making the imposition of boundary conditions as easy as that in the finite element method.Four numerical examples are studied to demonstrate the validity and accuracy of the proposedwavelet method.The results showthat the use ofmodified Shishkin nodes can significantly reduce numerical oscillation near the boundary layer.Compared with many other methods,the proposed method possesses satisfactory accuracy and efficiency.The theoretical and numerical results demonstrate that the order of theε-uniform convergence of this wavelet method can reach 5. 展开更多
关键词 Wavelet multi-resolution interpolation Galerkin singularly perturbed boundary value problems mesh-free method Shishkin node boundary layer
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The Demographic Problem in Greece:Consequences and Solutions
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作者 Adrianos Pavlopoulos Theodoros Rachiotis 《Journal of Environmental Science and Engineering(A)》 CAS 2024年第3期100-110,共11页
Globally,population dynamics are shifting towards increased life expectancy,and many countries,including Greece,face significant demographic challenges.Greece is particularly impacted by one of the lowest birth rates ... Globally,population dynamics are shifting towards increased life expectancy,and many countries,including Greece,face significant demographic challenges.Greece is particularly impacted by one of the lowest birth rates in the world and a rapidly aging population.This demographic shift places unprecedented pressure on the nation’s pension systems and economic stability,as more people retire than enter the workforce.This study aims to explore the historical factors contributing to Greece’s demographic situation,analyze the consequences of current trends,and propose strategic solutions.The research utilizes a literature review approach and the case study of Greece to understand the depth and breadth of the demographic crisis.Key areas of focus include the declining birth rate,the economic implications of an aging population,and the potential of migration and policy reform to rejuvenate demographic dynamics.The study evaluates various policy interventions from other countries to propose a tailored,multi-faceted strategy for Greece.These strategies emphasize economic incentives for young families,improved childcare and parental support,healthcare investment,and inclusive migration policies to enhance workforce numbers.This comprehensive approach seeks to provide actionable insights that can help Greece mitigate the effects of demographic decline and foster a more sustainable future,aligning policy interventions with socio-economic and cultural realities. 展开更多
关键词 Demographic problem low birth rate IMPLICATIONS POLICIES REFORMS
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The Regularity of Solutions to Mixed Boundary Value Problems of Second-Order Elliptic Equations with Small Angles
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作者 Mingyu Wu 《Journal of Applied Mathematics and Physics》 2024年第4期1043-1049,共7页
This paper considers the regularity of solutions to mixed boundary value problems in small-angle regions for elliptic equations. By constructing a specific barrier function, we proved that under the assumption of suff... This paper considers the regularity of solutions to mixed boundary value problems in small-angle regions for elliptic equations. By constructing a specific barrier function, we proved that under the assumption of sufficient regularity of boundary conditions and coefficients, as long as the angle is sufficiently small, the regularity of the solution to the mixed boundary value problem of the second-order elliptic equation can reach any order. 展开更多
关键词 Mixed Boundary Value problems for Elliptic Equations Small-Angle Boundary Value problems Regularity of solutions to Elliptic Equations
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An Efficient Approach for Transforming Unbalanced Transportation Problems into Balanced Problems in Order to Find Optimal Solutions
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作者 Abdur Rashid Md. Amirul Islam 《American Journal of Operations Research》 2024年第1期74-86,共13页
In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain a... In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain and logistics situations where the available supply of goods may not precisely match the demand at different locations. To deal with an unbalanced transportation problem (UTP), it is essential first to convert it into a balanced transportation problem (BTP) to find an initial basic feasible solution (IBFS) and hence the optimal solution. The present paper is concerned with introducing a new approach to convert an unbalanced transportation problem into a balanced one and as a consequence to obtain optimum total transportation cost. Numerical examples are provided to demonstrate the suggested method. 展开更多
关键词 Unbalanced Transportation problem (UTP) Supply DEMAND Initial solution Optimal solution
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On the “Onion Husk” Algorithm for Approximate Solution of the Traveling Salesman Problem
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作者 Mikhail E. Abramyan Nikolai I. Krainiukov Boris F. Melnikov 《Journal of Applied Mathematics and Physics》 2024年第4期1557-1570,共14页
The paper describes some implementation aspects of an algorithm for approximate solution of the traveling salesman problem based on the construction of convex closed contours on the initial set of points (“cities”) ... The paper describes some implementation aspects of an algorithm for approximate solution of the traveling salesman problem based on the construction of convex closed contours on the initial set of points (“cities”) and their subsequent combination into a closed path (the so-called contour algorithm or “onion husk” algorithm). A number of heuristics related to the different stages of the algorithm are considered, and various variants of the algorithm based on these heuristics are analyzed. Sets of randomly generated points of different sizes (from 4 to 90 and from 500 to 10,000) were used to test the algorithms. The numerical results obtained are compared with the results of two well-known combinatorial optimization algorithms, namely the algorithm based on the branch and bound method and the simulated annealing algorithm. . 展开更多
关键词 Branch and Bound Method Contour Algorithm “Onion Husk” Algorithm Simulated Annealing Method Traveling Salesman problem
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Gradient Estimate of Solutions to a Class of Mean Curvature Equations with Prescribed Contact Angle Boundary Problem
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作者 Yuan Shengtong Han Fei 《数学理论与应用》 2024年第3期94-105,共12页
This paper studies the prescribed contact angle boundary value problem of a certain type of mean curvature equation.Applying the maximum principle and the moving frame method and based on the location of the maximum p... This paper studies the prescribed contact angle boundary value problem of a certain type of mean curvature equation.Applying the maximum principle and the moving frame method and based on the location of the maximum point,the boundary gradient estimation of the solutions to the equation is obtained. 展开更多
关键词 Moving frame Maximum principle Prescribed contact angle boundary value problem Mean curvature equation
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A Study on the Problems and Solution Paths in the Conduct of Elderly Competency Assessment
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作者 Jia Di Bu Ri Ha 《Journal of Clinical and Nursing Research》 2024年第7期184-190,共7页
Exploring the problems existing in the process of carrying out an elderly competency assessment aims to provide useful references for its improvement.Starting from the importance of elderly competency assessment in th... Exploring the problems existing in the process of carrying out an elderly competency assessment aims to provide useful references for its improvement.Starting from the importance of elderly competency assessment in the field of elderly services,this paper analyses the problems in the process of carrying out elderly competency assessment and explores the corresponding solutions.The analysis finds that problems in the process of carrying out elderly competency assessment are inevitable,but as long as the study continues to explore and innovate and actively seek solution paths,the study will be able to overcome these difficulties and provide the elderly with better and more efficient elderly services. 展开更多
关键词 ELDERLY Competence assessment problemS solution paths
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The Problems and Solutions of Enterprise Financial Management in the Perspective of Digital Economy
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作者 Taoyuan Wan 《Proceedings of Business and Economic Studies》 2024年第5期206-212,共7页
From the perspective of the digital economy,enterprise financial management is facing unprecedented challenges and opportunities.Traditional financial management models are no longer suited to current development need... From the perspective of the digital economy,enterprise financial management is facing unprecedented challenges and opportunities.Traditional financial management models are no longer suited to current development needs.Fine-tuning financial management is essential to support the modernization of enterprises,guard against operational risks,and promote coordination across the entire value chain for greater economic efficiency.With the help of digital technology,data-driven,highly interconnected,and intelligent decision-making processes are becoming more prominent,profoundly transforming the operational and financial management models of enterprises.This enables financial management to keep pace with modern developments.In light of this,the paper explores the connotations and mechanisms of the digital economy and enterprise financial management,clarifies relevant conceptual characteristics,and identifies problems in financial management under the digital economy.It also offers strategies for optimization and problem-solving,with the aim of providing valuable insights for educators and practitioners. 展开更多
关键词 Digital economy ENTERPRISE Financial management Existence problems solution strategy
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Radon Measure Solutions to Riemann Problems for Isentropic Compressible Euler Equations of Polytropic Gases 被引量:1
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作者 Yunjuan Jin Aifang Qu Hairong Yuan 《Communications on Applied Mathematics and Computation》 2023年第3期1097-1129,共33页
We solve the Riemann problems for isentropic compressible Euler equations of polytropic gases in the class of Radon measures,and the solutions admit the concentration of mass.It is found that under the requirement of ... We solve the Riemann problems for isentropic compressible Euler equations of polytropic gases in the class of Radon measures,and the solutions admit the concentration of mass.It is found that under the requirement of satisfying the over-compressing entropy condition:(i)there is a unique delta shock solution,corresponding to the case that has two strong classical Lax shocks;(ii)for the initial data that the classical Riemann solution contains a shock wave and a rarefaction wave,or two shocks with one being weak,there are infinitely many solutions,each consists of a delta shock and a rarefaction wave;(iii)there are no delta shocks for the case that the classical entropy weak solutions consist only of rarefaction waves.These solutions are self-similar.Furthermore,for the generalized Riemann problem with mass concentrated initially at the discontinuous point of initial data,there always exists a unique delta shock for at least a short time.It could be prolonged to a global solution.Not all the solutions are self-similar due to the initial velocity of the concentrated point-mass(particle).Whether the delta shock solutions constructed satisfy the over-compressing entropy condition is clarified.This is the first result on the construction of singular measure solutions to the compressible Euler system of polytropic gases,that is strictly hyperbolic,and whose characteristics are both genuinely nonlinear.We also discuss possible physical interpretations and applications of these new solutions. 展开更多
关键词 Compressible Euler equations Radon measure solution Delta shock Riemann problem NON-UNIQUENESS
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Association of preschool children behavior and emotional problems with the parenting behavior of both parents 被引量:1
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作者 Su-Mei Wang Shuang-Qin Yan +4 位作者 Fang-Fang Xie Zhi-Ling Cai Guo-Peng Gao Ting-Ting Weng Fang-Biao Tao 《World Journal of Clinical Cases》 SCIE 2024年第6期1084-1093,共10页
BACKGROUND Parental behaviors are key in shaping children’s psychological and behavioral development,crucial for early identification and prevention of mental health issues,reducing psychological trauma in childhood.... BACKGROUND Parental behaviors are key in shaping children’s psychological and behavioral development,crucial for early identification and prevention of mental health issues,reducing psychological trauma in childhood.AIM To investigate the relationship between parenting behaviors and behavioral and emotional issues in preschool children.METHODS From October 2017 to May 2018,7 kindergartens in Ma’anshan City were selected to conduct a parent self-filled questionnaire-Health Development Survey of Preschool Children.Children’s Strength and Difficulties Questionnaire(Parent Version)was applied to measures the children’s behavioral and emotional performance.Parenting behavior was evaluated using the Parental Behavior Inventory.Binomial logistic regression model was used to analyze the association between the detection rate of preschool children’s behavior and emotional problems and their parenting behaviors.RESULTS High level of parental support/participation was negatively correlated with conduct problems,abnormal hyperactivity,abnormal total difficulty scores and abnormal prosocial behavior problems.High level of maternal support/participation was negatively correlated with abnormal emotional symptoms and abnormal peer interaction in children.High level of parental hostility/coercion was positively correlated with abnormal emotional symptoms,abnormal conduct problems,abnormal hyperactivity,abnormal peer interaction,and abnormal total difficulty scores in children(all P<0.05).Moreover,paternal parenting behaviors had similarly effects on behavior and emotional problems of preschool children compared with maternal parenting behaviors(all P>0.05),after calculating ratio of odds ratio values.CONCLUSION Our study found that parenting behaviors are associated with behavioral and emotional issues in preschool children.Overall,the more supportive or involved the parents are,the fewer behavioral and emotional problems the children experience;conversely,the more hostile or controlling the parents are,the more behavioral and emotional problems the children face.Moreover,the impact of fathers’parenting behaviors on preschool children’s behavior and emotions is no less significant than that of mothers’parenting behaviors. 展开更多
关键词 CHILDREN Preschool age PARENTING BEHAVIORAL Parenting problems
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New Approach to Find Initial Basic Feasible Solution (IBFS) for Optimal Solution in Transportation Problem
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作者 Shubham Raval 《Open Journal of Applied Sciences》 CAS 2023年第2期207-211,共5页
Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for tran... Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for transportation problem which reduces cost of transportation more than any transportation method such as LCM, northwest, Vogel’s approximation and so on. This method has been illustrated by taking an example;afterwards, it compares basic initial feasible solution with other methods IBF and optimal dictate solutions such as MODI and Steppingstone method. 展开更多
关键词 Transportation problem New Approach for Transportation problem Initial Basic Feasible solution Minimizing Transportation Time
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The Simplest Possible Fully Correct Solution of the Clay Millennium Problem about P vs. NP. A Simple Proof That P ≠ NP = EXPTIME
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作者 Konstantinos E. Kyritsis 《Journal of Computer and Communications》 2023年第8期181-194,共14页
In the current paper, I present probably the simplest possible abstract formal proof that P ≠ NP, and NP = EXPTIME, in the context of the standard mathematical set theory of computational complexity and deterministic... In the current paper, I present probably the simplest possible abstract formal proof that P ≠ NP, and NP = EXPTIME, in the context of the standard mathematical set theory of computational complexity and deterministic Turing machines. My previous publications about the solution of the P vs. NP with the same result NP = EXPTIME, to be fully correct and understandable need the Lemma 4.1 and its proof of the current paper. The arguments of the current paper in order to prove NP = EXPTME are even simpler than in my previous publications. The strategy to solve the P vs. NP problem in the current paper (and in my previous publications) is by starting with an EXPTIME-complete language (problem) and proving that it has a re-formulation as an NP-class language, thus NP = EXPTIME. The main reason that the scientific community has missed so far such a simple proof, is because of two factors 1) It has been tried extensively but in vain to simplify the solutions of NP-complete problems from exponential time algorithms to polynomial time algorithms (which would be a good strategy only if P = NP) 2) It is believed that the complexity class NP is strictly a subclass to the complexity class EXPTIME (in spite the fact that any known solution to any of the NP-complete problems is not less than exponential). The simplicity of the current solution would have been missed if 2) was to be believed true. So far the majority of the relevant scientific community has considered this famous problem not yet solved. The present results definitely solve the 3rd Clay Millennium Problem about P versus NP in a simple, abstract and transparent way that the general scientific community, but also the experts of the area, can follow, understand and therefore become able to accept. 展开更多
关键词 3rd Clay Millennium problem EXPTIME-Complete problems NP-Complexity P-Complexity
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POSITIVE CLASSICAL SOLUTIONS OF DIRICHLET PROBLEM FOR THE STEADY RELATIVISTIC HEAT EQUATION
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作者 杨田洁 袁光伟 《Acta Mathematica Scientia》 SCIE CSCD 2023年第5期2279-2290,共12页
In this paper,for a bounded C2 domain,we prove the existence and uniqueness of positive classical solutions to the Dirichlet problem for the steady relativistic heat equation with a class of restricted positive C2 bou... In this paper,for a bounded C2 domain,we prove the existence and uniqueness of positive classical solutions to the Dirichlet problem for the steady relativistic heat equation with a class of restricted positive C2 boundary data.We have a non-existence result,which is the justification for taking into account the restricted boundary data.There is a smooth positive boundary datum that precludes the existence of the positive classical solution. 展开更多
关键词 Dirichlet problem steady relativistic heat equation classical solution
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THE GLOBAL SOLUTION AND BLOWUP OF A SPATIOTEMPORAL EIT PROBLEM WITH A DYNAMICAL BOUNDARY CONDITION
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作者 谢明洪 谭忠 《Acta Mathematica Scientia》 SCIE CSCD 2023年第4期1881-1914,共34页
We study a spatiotemporal EIT problem with a dynamical boundary condition for the fractional Dirichlet-to-Neumann operator with a critical exponent.There are three major ingredients in this paper.The first is the fini... We study a spatiotemporal EIT problem with a dynamical boundary condition for the fractional Dirichlet-to-Neumann operator with a critical exponent.There are three major ingredients in this paper.The first is the finite time blowup and the decay estimate of the global solution with a lower-energy initial value.The second ingredient is the L^(q)(2 ≤q <∞) estimate of the global solution applying the Moser iteration,which allows us to show that any global solution is a classical solution.The third,which is the main ingredient of this paper,explores the long time asymptotic behavior of global solutions close to the stationary solution and the bubbling phenomenons by means of a concentration compactness principle. 展开更多
关键词 spatiotemporal EIT problem fractional Dirichlet-to-Neumann operator critical exponent bubbling phenomena
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Sign-Changing Solutions for Superlinear Kirchhoff Type Problem via the Nehari Method
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作者 Xiaohan Duan Guanggang Liu 《Journal of Applied Mathematics and Physics》 2023年第7期2093-2102,共10页
In this paper, we consider a class of Kirchhoff type problem with superlinear nonlinearity. A sign-changing solution with exactly two nodal domains will be obtained by combining the Nehari method and an iterative tech... In this paper, we consider a class of Kirchhoff type problem with superlinear nonlinearity. A sign-changing solution with exactly two nodal domains will be obtained by combining the Nehari method and an iterative technique. 展开更多
关键词 Kirchhoff Type problem Nehari Method Iterative Technique
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To the Solution of a Spherically Symmetric Problem of General Relativity
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作者 Valery V. Vasiliev Leonid V. Fedorov 《Journal of Modern Physics》 CAS 2023年第2期147-159,共13页
The paper is devoted to the spherically symmetric problem of General Relativity. Existing solutions obtained by K. Schwarzschild and V. Fock are presented and discussed. A special geometry of the Riemannian space indu... The paper is devoted to the spherically symmetric problem of General Relativity. Existing solutions obtained by K. Schwarzschild and V. Fock are presented and discussed. A special geometry of the Riemannian space induced by gravitation is proposed. According to this geometry the four-dimensional Riemannian space is assumed to be Euclidean with respect to the space coordinates and Riemannian with respect to the time coordinate. The solution of the Einstein equations for the empty space with this geometry coincides with the solution in Gullstand-Painlever coordinates. In application to the found solution, the problem of the light trajectory deviation in the vicinity of Sun and the problem of escape velocity are discussed. 展开更多
关键词 General Relativity Spherically Symmetric problem
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Solution to the “Three-Body Problem” in the Light of the Maximum Ordinality Principle, as a “Suggestion” for a Ri-Orientation of the Present Scientific Perspective in “Favor” of the “Irreducible Quality”
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作者 Corrado Giannantoni 《Journal of Applied Mathematics and Physics》 2023年第1期209-259,共51页
This paper presents the Solution to the “Three-body Problem” in the Light of the Maximum Ordinality Principle. In the first part, however, it starts with the Solution to the Solar System, made up of “11 Bodies”. T... This paper presents the Solution to the “Three-body Problem” in the Light of the Maximum Ordinality Principle. In the first part, however, it starts with the Solution to the Solar System, made up of “11 Bodies”. This is because, in such a context, the “Three-body Problem” can be analyzed in its all descriptive possibilities. Nonetheless, the paper also presents the Solution to the “Three-body Problem” with reference to Systems totally independent from the Solar System, such as, for example, the “Triple Stars” and the “Triple Galaxies”. In this way, the paper offers a sufficiently complete framework concerning the Solution to the “Three-body Problem”, always in the Light of the Maximum Ordinality Principle, described in detail in Appendix A. 展开更多
关键词 Three-Body problem Light of the Maximum Ordinality Principle solution to the Solar System
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Three-Drug Therapies in Psychiatry in the Light of the Maximum Ordinality Principle and the Explicit Solution to the “Three-Body Problem”—D.D. 23 Luglio 2023, Tempo Ordinario (3.00 e 10.20)
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作者 Corrado Giannantoni 《Journal of Applied Mathematics and Physics》 2023年第8期2267-2308,共42页
The present paper aims at showing the possible adoption in Psychiatry of a general methodology finalized to prescribe the most appropriate Therapy based on the knowledge of its correlative effects in advance, instead ... The present paper aims at showing the possible adoption in Psychiatry of a general methodology finalized to prescribe the most appropriate Therapy based on the knowledge of its correlative effects in advance, instead of recognizing them ex post. The specific case here considered is the “bipolar disorder”, in which the adoption of three different drugs is the most common practice, although with a possible differentiation between the prescription in the morning and in the evening, respectively. Thus, the proposed methodology will consider the Ordinal Interactions between the various drugs by evaluating their combined effects, which will result as being not a simple additive “sum”, because they are evaluated on the basis of the Maximum Ordinality Principle (MOP) and, in addition, in Adherence to the Explicit Solution to the “Three-Body Problem”. In this way the Methodology here proposed is able to suggest how to account for the synergistic effects of the various drugs, especially when the latter are characterized by different concentrations and, at the same time, by generally different half-lives respectively. 展开更多
关键词 Three-Drug Therapies Bipolar Disorder Psychiatric Therapies Maximum Ordinality Principle (MOP) “Three-Body problem
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