Process Philosophical Adventures of Applied Ontology

The paper is devoted to the new sphere of applied process ontology. It first makes a short review of the recent investigations in that area. Then it stresses on the importance of applied process ontology. Next the main methodological approaches of applied process ontology are considered： the ＂top down＂ and ＂bottom up＂ approaches. It is argued about the necessity and fruitfulness to combine both ＂top down＂ and ＂bottom up＂ approaches, and not to rely on one of them only. An example is given of the important role of process ontology as general methodological framework for the building up of regional formal ontology. Finally, the idea of variable ontological categories is stressed on and argued for its fruitfulness.

Spatiotemporal microRNA profile in peripheral nerve regeneration:miR-138 targets vimentin and inhibits Schwann cell migration and proliferation

While the peripheral nervous system has regenerative ability,restoration of sufficient function remains a challenge.Vimentin has been shown to be localized in axonal growth fronts and associated with nerve regeneration,including myelination,neuroplasticity,kinase signaling in nerve axoplasm,and cell migration;however,the mechanisms regulating its expression within Schwann cell（SC） remain unexplored.The aim of this study was to profile the spatial and temporal expression profile of micro RNA（mi RNA） in a regenerating rat sciatic nerve after transection,and explore the potential role of mi R-138-5 p targeting vimentin in SC proliferation and migration.A rat sciatic nerve transection model,utilizing a polyethylene nerve guide,was used to investigate mi RNA expression at 7,14,30,60,and 90 days during nerve regeneration.Relative levels of mi RNA expression were determined using microarray analysis and subsequently validated with quantitative real-time polymerase chain reaction.In vitro assays were conducted with cultured Schwann cells transfected with mi RNA mimics and assessed for migratory and proliferative potential.The top seven dysregulated mi RNAs reported in this study have been implicated in cell migration elsewhere,and GO and KEGG analyses predicted activities essential to wound healing.Transfection of one of these,mi RNA-138-5 p,into SCs reduced cell migration and proliferation.mi R-138-5 p has been shown to directly target vimentin in cancer cells,and the luciferase assay performed here in rat Schwann cells confirmed it.These results detail a role of mi R-138-5 p in rat peripheral nerve regeneration and expand on reports of it as an important regulator in the peripheral nervous system.

Integrating NLP and Ontology Matching into a Unified System for Automated Information Extraction from Geological Hazard Reports

Many detailed data on past geological hazard events are buried in geological hazard reports and have not been fully utilized. The growing developments in geographic information retrieval and temporal information retrieval offer opportunities to analyse this wealth of data to mine the spatiotemporal evolution of geological disaster occurrence and enhance risk decision making. This study presents a combined NLP and ontology matching information extraction framework for automatically recognizing semantic and spatiotemporal information from geological hazard reports. This framework mainly extracts unstructured information from geological disaster reports through named entity recognition, ontology matching and gazetteer matching to identify and annotate elements, thus enabling users to quickly obtain key information and understand the general content of disaster reports. In addition, we present the final results obtained from the experiments through a reasonable visualization and analyse the visual results. The extraction and retrieval of semantic information related to the dynamics of geohazard events are performed from both natural and human perspectives to provide information on the progress of events.

Ontology-based interoperability solutions for textile supply chain

Existence of interoperability within the enterprises is essential for textile supply chain to efficiently face the challenges from contemporary competitors,to find new business opportunities and to render better customer service.Exchange of business documents,being semantically consistent,is the way to achieve interoperability.However,heterogeneity of the structures of the enterprises poses challenges for establishing interoperability.Ontology based semantic interoperability framework has now been proven as an effective solution for enterprise interoperability.In this paper,the existing ontology-based interoperability solutions in the context of textile supply chain have been compiled and research gaps have been identified.The ontological methods,such as unified process for ontology（UPON） and methontology have been analyzed,and UPON have been shown as a suitable ontology development method for textile supply chain.