MAYERTON HOLDINGS LTD, a leading refractory engineering solutions provider and a high quality castable and refractories brick manufacturer, announced it signed a definitive agreement for the sale of its 100% equity in...MAYERTON HOLDINGS LTD, a leading refractory engineering solutions provider and a high quality castable and refractories brick manufacturer, announced it signed a definitive agreement for the sale of its 100% equity interest in Dalian Mayerton Refractories Co. Ltd. ( " DMR" ) to Magnesita Refratarios S.A. on April 22, 2013. DMR is a refractory brick manufacturing facility in Dalian, China (Liaoning Province).展开更多
Second language acquisition can not be understood without addressing the interaction between language and cognition. Cognitive theory can extend to describe learning strategies as complex cognitive skills. Theoretical...Second language acquisition can not be understood without addressing the interaction between language and cognition. Cognitive theory can extend to describe learning strategies as complex cognitive skills. Theoretical developments in Anderson’s production systems cover a broader range of behavior than other theories, including comprehension and production of oral and written texts as well as comprehension, problem solving, and verbal learning.Thus Anderson’s cognitive theory can be served as a rationale for learning strategy studies in second language acquisition.展开更多
The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns.Cardiovascular complications associated with diabetes are the leading cause o...The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns.Cardiovascular complications associated with diabetes are the leading cause of morbidity and mortality.The cardiovascular diseases that accompany diabetes include angina,myocardial infarction,stroke,peripheral artery disease,and congestive heart failure.Among the various risk factors generated secondary to hyperglycemic situations,advanced glycation end products(AGEs)are one of the important targets for future diagnosis and prevention of diabetes.In the last decade,AGEs have drawn a lot of attention due to their involvement in diabetic pathophysiology.AGEs can be derived exogenously and endogenously through various pathways.These are a nonhomogeneous,chemically diverse group of compounds formed nonenzymatically by condensation between carbonyl groups of reducing sugars and free amino groups of protein,lipids,and nucleic acid.AGEs mediate their pathological effects at the cellular and extracellular levels by multiple pathways.At the cellular level,they activate signaling cascades via the receptor for AGEs and initiate a complex series of intracellular signaling resulting in reactive oxygen species generation,inflammation,cellular proliferation,and fibrosis that may possibly exacerbate the damaging effects on cardiac functions in diabetics.AGEs also cause covalent modifications and cross-linking of serum and extracellular matrix proteins;altering their structure,stability,and functions.Early diagnosis of diabetes may prevent its progression to complications and decrease its associated comorbidities.In the present review,we recapitulate the role of AGEs as a crucial mediator of hyperglycemia-mediated detrimental effects in diabetes-associated complications.Furthermore,this review presents an overview of future perspectives for new therapeutic interventions to ameliorate cardiovascular complications in diabetes.展开更多
Comparison effects have been studied extensively in many fields.In particular,existing operations management articles have discussed the impact of comparison effects on enterprises'production and pricing decisions...Comparison effects have been studied extensively in many fields.In particular,existing operations management articles have discussed the impact of comparison effects on enterprises'production and pricing decisions.Research has also shown that consumers'purchasing decisions are primarily determined by three factors:product quality,selling price,and comparison effects.The current study introduces the concepts of social and temporal comparison effects to examine how comparison effects influence a monopolist's production quality and pricing strategy for substitutable products.Results reveal the following:(1)Setting different prices for even two types of substitutable products with negligible quality differences can divide customers into three groups under the influence of social comparison effects in a single-stage model.(2)The monopolist should avoid using a price discrimination strategy in which products with a short market life cycle have the same quality but different prices.(3)When the market life cycle of products is sufficiently long in the single-product market and the market with two substitutable products,the monopolist's optimal choice in the second stage is to keep production quality constant and increase the selling price.Consequently,the number of buyers does not decrease because of temporal comparison effects.Therefore,the firm increases its revenue.(4)For the market with two substitutable products with quality differences,one approximate optimal strategy for the enterprise in the second stage is to keep the selling price constant with the assumption that product quality cannot be adjusted after the first period.At this point,the consumption situation in the market is the same as that in the first stage.Therefore,when no external constraints exist,the monopolist firm can obtain more benefits in the second stage than in the first stage by exploiting the temporal comparison effects of consumers in the second stage.(5)When consumer identity information can be confirmed in the market,social comparison effects,similar to temporal comparison effects,could help the enterprise increase its price and profit while maintaining product quality.These social and temporal comparison effects constrain consumers.Thus,the number of people who continueto buyproducts does not decrease.展开更多
This study examines the optimal pricing and production strategy of a closed-loop supply chain consisting of a manufacturer, a recycler, and consumers. Considering the cannibalization and promotion effects of remanufac...This study examines the optimal pricing and production strategy of a closed-loop supply chain consisting of a manufacturer, a recycler, and consumers. Considering the cannibalization and promotion effects of remanufactured products on new and secondhand products, we constructed Stackelberg game models under different scenarios. We analyze the impact of the changes in the two effects on the optimal prices and production strategies of the manufacturer and recycler, as well as their countermeasures. We find that (i) how the cannibalization and promotional effects influence the manufacturer and the recycler's pricing and production strategies differ under different scenarios;(ii) when the two effects exceed a threshold, the manufacturer abandons new or remanufactured products, and the recycler prefers to stop production on its new products or continue to remanufacture products;and (iii) the two effects always reduce the profits of the manufacturer and increase the profits of the recycler.展开更多
Inappropriate nitrogen fertilizer management for the intensive Chinese vegetable production has caused low N use efficiency(NUE),high reactive nitrogen(Nr)losses and serious environmental risks with limited yield incr...Inappropriate nitrogen fertilizer management for the intensive Chinese vegetable production has caused low N use efficiency(NUE),high reactive nitrogen(Nr)losses and serious environmental risks with limited yield increase.Innovative N management strategy is an urgent need to achieve sustainable vegetable production.This paper summarizes recent studies on Nr losses and identifies the limitations from Chinese vegetable production systems and proposes three steps for sustainable N management in Chinese vegetable production.The three N management steps include,but are not limited to,(1)knowledge-based optimization of N fertilizer rate strategy,which maintains soil N supply to meet the dynamic vegetable demand in time,space and quantity;(2)innovative products and technology,which regulates the soil N forms and promotes the vegetable root growth to reduce the Nr loss;(3)integrated knowledge and products strategy(IKPS).The knowledge-based optimization of N fertilizer rate strategy and innovative products and technology,can maintain or increase vegetable yield,significantly improve NUE,and mitigate the region-specific and crop-specific Nr losses.More importantly,IKPS,based on combination of in-season root-zone N management strategy,innovative products and technology,and best crop cultivation management,is needed to produce more vegetables with lower Nr losses.展开更多
Industrial development can enrich people's lives, but it also causes environmental pollution, which is an area of significant concern among governments, consumers, and companies. Governments formulate some environmen...Industrial development can enrich people's lives, but it also causes environmental pollution, which is an area of significant concern among governments, consumers, and companies. Governments formulate some environmental policies, which motivate industry by providing greater incentives for green product development. Consumers are classified into two groups - ordinary and green market segments - according to their environmental awareness and attitudes. In this regard, companies need to reconsider their primary product design strategies. By investigating the interactions among customers' preferences, firms' product strategies, and government subsidy policies, this paper presents a theoretical model for new product design strategies. After detailed theoretical analysis of such strategies, we found that to motivate firms to choose environmentally friendly product design strategies, governments should inaugurate effective subsidy policies. After simultaneously considering environmental issues and firms' benefits, we designed a subsidy policy. With such a policy, firms can change their primary product design strategies and develop both green and ordinary products, thereby increasing the firms' profits and improving the total environmental quality.展开更多
文摘MAYERTON HOLDINGS LTD, a leading refractory engineering solutions provider and a high quality castable and refractories brick manufacturer, announced it signed a definitive agreement for the sale of its 100% equity interest in Dalian Mayerton Refractories Co. Ltd. ( " DMR" ) to Magnesita Refratarios S.A. on April 22, 2013. DMR is a refractory brick manufacturing facility in Dalian, China (Liaoning Province).
文摘Second language acquisition can not be understood without addressing the interaction between language and cognition. Cognitive theory can extend to describe learning strategies as complex cognitive skills. Theoretical developments in Anderson’s production systems cover a broader range of behavior than other theories, including comprehension and production of oral and written texts as well as comprehension, problem solving, and verbal learning.Thus Anderson’s cognitive theory can be served as a rationale for learning strategy studies in second language acquisition.
文摘The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns.Cardiovascular complications associated with diabetes are the leading cause of morbidity and mortality.The cardiovascular diseases that accompany diabetes include angina,myocardial infarction,stroke,peripheral artery disease,and congestive heart failure.Among the various risk factors generated secondary to hyperglycemic situations,advanced glycation end products(AGEs)are one of the important targets for future diagnosis and prevention of diabetes.In the last decade,AGEs have drawn a lot of attention due to their involvement in diabetic pathophysiology.AGEs can be derived exogenously and endogenously through various pathways.These are a nonhomogeneous,chemically diverse group of compounds formed nonenzymatically by condensation between carbonyl groups of reducing sugars and free amino groups of protein,lipids,and nucleic acid.AGEs mediate their pathological effects at the cellular and extracellular levels by multiple pathways.At the cellular level,they activate signaling cascades via the receptor for AGEs and initiate a complex series of intracellular signaling resulting in reactive oxygen species generation,inflammation,cellular proliferation,and fibrosis that may possibly exacerbate the damaging effects on cardiac functions in diabetics.AGEs also cause covalent modifications and cross-linking of serum and extracellular matrix proteins;altering their structure,stability,and functions.Early diagnosis of diabetes may prevent its progression to complications and decrease its associated comorbidities.In the present review,we recapitulate the role of AGEs as a crucial mediator of hyperglycemia-mediated detrimental effects in diabetes-associated complications.Furthermore,this review presents an overview of future perspectives for new therapeutic interventions to ameliorate cardiovascular complications in diabetes.
文摘Comparison effects have been studied extensively in many fields.In particular,existing operations management articles have discussed the impact of comparison effects on enterprises'production and pricing decisions.Research has also shown that consumers'purchasing decisions are primarily determined by three factors:product quality,selling price,and comparison effects.The current study introduces the concepts of social and temporal comparison effects to examine how comparison effects influence a monopolist's production quality and pricing strategy for substitutable products.Results reveal the following:(1)Setting different prices for even two types of substitutable products with negligible quality differences can divide customers into three groups under the influence of social comparison effects in a single-stage model.(2)The monopolist should avoid using a price discrimination strategy in which products with a short market life cycle have the same quality but different prices.(3)When the market life cycle of products is sufficiently long in the single-product market and the market with two substitutable products,the monopolist's optimal choice in the second stage is to keep production quality constant and increase the selling price.Consequently,the number of buyers does not decrease because of temporal comparison effects.Therefore,the firm increases its revenue.(4)For the market with two substitutable products with quality differences,one approximate optimal strategy for the enterprise in the second stage is to keep the selling price constant with the assumption that product quality cannot be adjusted after the first period.At this point,the consumption situation in the market is the same as that in the first stage.Therefore,when no external constraints exist,the monopolist firm can obtain more benefits in the second stage than in the first stage by exploiting the temporal comparison effects of consumers in the second stage.(5)When consumer identity information can be confirmed in the market,social comparison effects,similar to temporal comparison effects,could help the enterprise increase its price and profit while maintaining product quality.These social and temporal comparison effects constrain consumers.Thus,the number of people who continueto buyproducts does not decrease.
文摘This study examines the optimal pricing and production strategy of a closed-loop supply chain consisting of a manufacturer, a recycler, and consumers. Considering the cannibalization and promotion effects of remanufactured products on new and secondhand products, we constructed Stackelberg game models under different scenarios. We analyze the impact of the changes in the two effects on the optimal prices and production strategies of the manufacturer and recycler, as well as their countermeasures. We find that (i) how the cannibalization and promotional effects influence the manufacturer and the recycler's pricing and production strategies differ under different scenarios;(ii) when the two effects exceed a threshold, the manufacturer abandons new or remanufactured products, and the recycler prefers to stop production on its new products or continue to remanufacture products;and (iii) the two effects always reduce the profits of the manufacturer and increase the profits of the recycler.
基金supported by the Regional Innovation and Development Joint Fund project of National Foundation of China(U20A2047).
文摘Inappropriate nitrogen fertilizer management for the intensive Chinese vegetable production has caused low N use efficiency(NUE),high reactive nitrogen(Nr)losses and serious environmental risks with limited yield increase.Innovative N management strategy is an urgent need to achieve sustainable vegetable production.This paper summarizes recent studies on Nr losses and identifies the limitations from Chinese vegetable production systems and proposes three steps for sustainable N management in Chinese vegetable production.The three N management steps include,but are not limited to,(1)knowledge-based optimization of N fertilizer rate strategy,which maintains soil N supply to meet the dynamic vegetable demand in time,space and quantity;(2)innovative products and technology,which regulates the soil N forms and promotes the vegetable root growth to reduce the Nr loss;(3)integrated knowledge and products strategy(IKPS).The knowledge-based optimization of N fertilizer rate strategy and innovative products and technology,can maintain or increase vegetable yield,significantly improve NUE,and mitigate the region-specific and crop-specific Nr losses.More importantly,IKPS,based on combination of in-season root-zone N management strategy,innovative products and technology,and best crop cultivation management,is needed to produce more vegetables with lower Nr losses.
基金supported by the National Natural Science Foundation of China under Grant Nos.70725001, 70821001 and 7120103the Provincial Research Institutions of Anhui under Grant No.2012WLGH03
文摘Industrial development can enrich people's lives, but it also causes environmental pollution, which is an area of significant concern among governments, consumers, and companies. Governments formulate some environmental policies, which motivate industry by providing greater incentives for green product development. Consumers are classified into two groups - ordinary and green market segments - according to their environmental awareness and attitudes. In this regard, companies need to reconsider their primary product design strategies. By investigating the interactions among customers' preferences, firms' product strategies, and government subsidy policies, this paper presents a theoretical model for new product design strategies. After detailed theoretical analysis of such strategies, we found that to motivate firms to choose environmentally friendly product design strategies, governments should inaugurate effective subsidy policies. After simultaneously considering environmental issues and firms' benefits, we designed a subsidy policy. With such a policy, firms can change their primary product design strategies and develop both green and ordinary products, thereby increasing the firms' profits and improving the total environmental quality.