Objective: The objective of this study was to explore the medication rules and academic ideas of Professor Wang Yu-Ying in the treatment of climacteric syndrome(CLS) and to predict new prescriptions. Materials and Met...Objective: The objective of this study was to explore the medication rules and academic ideas of Professor Wang Yu-Ying in the treatment of climacteric syndrome(CLS) and to predict new prescriptions. Materials and Methods: The characteristics of frequency, clustering, four properties, and five flavors were analyzed, and new prescriptions were predicted through an artificial intelligence(AI)-based method. The potential pathways of new prescriptions were explored through network pharmacology-based analysis. Results: The top 16 medicinals used by Professor Wang Yu-Ying in the treatment of CLS included Danggui, Longgu, Muli, Fuling, Chuanxiong, Gancao, Xiangfu, and Tusizi. The AI method was applied to predict the basic prescription for treating CLS: Danggui 15 g, Duanlonggu 30 g, Duanmuli 30 g, Fuling 28 g, Chuanxiong 10 g, Gancao 6 g, Xiangfu 12 g, Tusizi 14 g, etc., Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses showed that the pathogenesis of CLS might be related to the estrogen pathway, involving typical steroid responses. Conclusions: This study summarized Professor Wang's medication experience in the treatment of CLS based on the data mining of clinical diagnoses and treatment cases. The AI method was used to predict the new prescription of CLS treatment, which was found to be reasonable by network pharmacology studies on its multi-target and multi-pathway mechanisms.展开更多
Tsinghua Professor Wang Xiaoyun was awarded the Qiushi Outstanding Scientist Prize at the 2006 annual meeting of the China Association for Science and Technology, held in the Great Hall of the People on September 16, ...Tsinghua Professor Wang Xiaoyun was awarded the Qiushi Outstanding Scientist Prize at the 2006 annual meeting of the China Association for Science and Technology, held in the Great Hall of the People on September 16, 2006.展开更多
It is with great sadness that I share the sorrowful news that mammalogy and wildlife science lost a respected scientist, patient teacher, and wonderful mentor on 10 February, 2016, when Professor Ying-Xiang Wang died ...It is with great sadness that I share the sorrowful news that mammalogy and wildlife science lost a respected scientist, patient teacher, and wonderful mentor on 10 February, 2016, when Professor Ying-Xiang Wang died in Kunming, Yunnan Province, due to heart failure following a lung infection. He is survived by his wife Professor Rui-Qing Liu, daughter Li Wang, son Tao Wang, daughter-in-law Qing Sun and granddaughter Jun-Qi Wang.展开更多
Xudong Wang obtained B.Eng. in Hydrogeology and Engineering Geology in 1990, M.Sc. in Environmental Science in 1998 and Ph.D. in Engineering Geology in 2003 from Lanzhou University, China. In 1991, he attended the Dun...Xudong Wang obtained B.Eng. in Hydrogeology and Engineering Geology in 1990, M.Sc. in Environmental Science in 1998 and Ph.D. in Engineering Geology in 2003 from Lanzhou University, China. In 1991, he attended the Dunhuang Academy and began his career in the conservation of grottoes, ancient wall-paintings and earthen sites, and the management of cultural heritage.展开更多
The first mid-term election of the U. S. in the new century took place on November 5, 2002. One third of the senators from the 107th Congress (34 out of 100), all representatives (435), 36 state governors, and numerou...The first mid-term election of the U. S. in the new century took place on November 5, 2002. One third of the senators from the 107th Congress (34 out of 100), all representatives (435), 36 state governors, and numerous local officials and legislators were to be elected or reelected. The resounding victory of the GOP in the congressional elections and the fact that the Democrats only got three more.展开更多
Professor Wang Rongpei has put forward the translation principle—"faithful in meaning and vivid in description"and put it into use. Through a series of analysis and contrast of different versions, this essa...Professor Wang Rongpei has put forward the translation principle—"faithful in meaning and vivid in description"and put it into use. Through a series of analysis and contrast of different versions, this essay would prove the rationality of Professor Wang Rongpei's translation principle.展开更多
文摘Objective: The objective of this study was to explore the medication rules and academic ideas of Professor Wang Yu-Ying in the treatment of climacteric syndrome(CLS) and to predict new prescriptions. Materials and Methods: The characteristics of frequency, clustering, four properties, and five flavors were analyzed, and new prescriptions were predicted through an artificial intelligence(AI)-based method. The potential pathways of new prescriptions were explored through network pharmacology-based analysis. Results: The top 16 medicinals used by Professor Wang Yu-Ying in the treatment of CLS included Danggui, Longgu, Muli, Fuling, Chuanxiong, Gancao, Xiangfu, and Tusizi. The AI method was applied to predict the basic prescription for treating CLS: Danggui 15 g, Duanlonggu 30 g, Duanmuli 30 g, Fuling 28 g, Chuanxiong 10 g, Gancao 6 g, Xiangfu 12 g, Tusizi 14 g, etc., Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses showed that the pathogenesis of CLS might be related to the estrogen pathway, involving typical steroid responses. Conclusions: This study summarized Professor Wang's medication experience in the treatment of CLS based on the data mining of clinical diagnoses and treatment cases. The AI method was used to predict the new prescription of CLS treatment, which was found to be reasonable by network pharmacology studies on its multi-target and multi-pathway mechanisms.
文摘Tsinghua Professor Wang Xiaoyun was awarded the Qiushi Outstanding Scientist Prize at the 2006 annual meeting of the China Association for Science and Technology, held in the Great Hall of the People on September 16, 2006.
文摘It is with great sadness that I share the sorrowful news that mammalogy and wildlife science lost a respected scientist, patient teacher, and wonderful mentor on 10 February, 2016, when Professor Ying-Xiang Wang died in Kunming, Yunnan Province, due to heart failure following a lung infection. He is survived by his wife Professor Rui-Qing Liu, daughter Li Wang, son Tao Wang, daughter-in-law Qing Sun and granddaughter Jun-Qi Wang.
文摘Xudong Wang obtained B.Eng. in Hydrogeology and Engineering Geology in 1990, M.Sc. in Environmental Science in 1998 and Ph.D. in Engineering Geology in 2003 from Lanzhou University, China. In 1991, he attended the Dunhuang Academy and began his career in the conservation of grottoes, ancient wall-paintings and earthen sites, and the management of cultural heritage.
文摘The first mid-term election of the U. S. in the new century took place on November 5, 2002. One third of the senators from the 107th Congress (34 out of 100), all representatives (435), 36 state governors, and numerous local officials and legislators were to be elected or reelected. The resounding victory of the GOP in the congressional elections and the fact that the Democrats only got three more.
文摘Professor Wang Rongpei has put forward the translation principle—"faithful in meaning and vivid in description"and put it into use. Through a series of analysis and contrast of different versions, this essay would prove the rationality of Professor Wang Rongpei's translation principle.
