Selecting method of districts with science and technology program’s priority support and its positive analysis

According to growth pole theory, this paper puts forward that when allocating regional science and technology (S&T) innovation resources based on S&T program, should abide the principle that important area receives priority support; Meanwhile, it designs method to ascertain district S&T advantage and S&T innovation resources utilizing efficiency as well as S&T developing speed by using component analysis and DEA method, and then constructs three-dimension selecting model,by which a positive research on Heilongjiang is made, the purpose of which is to offer scientific method support and decision-making foundation for making regional S&T program.

Sciatic nerve repair using adhesive bonding and a modified conduit

When repairing nerves with adhesives, most researchers place glue directly on the nerve stumps, but this method does not fix the nerve ends well and allows glue to easily invade the nerve ends. In this study, we established a rat model of completely transected sciatic nerve injury and re- paired it using a modified 1 cm-length conduit with inner diameter of 1.5 mm. Each end of the cylindrical conduit contains a short linear channel, while the enclosed central tube protects the nerve ends well Nerves were repaired with 2-octyl-cyanoacrylate and suture, which complement the function of the modified conduit. The results demonstrated that for the same conduit, the av- erage operation time using the adhesive method was much shorter than with the suture method. No significant differences were found between the two groups in sciatic function index, motor evoked potential latency, motor evoked potential amplitude, muscular recovery rate, number of medullated nerve fibers, axon diameter, or medullary sheath thickness. Thus, the adhesive method for repairing nerves using a modified conduit is feasible and effective, and reduces the operation time while providing an equivalent repair effect.

Satellite SAR observation of shallow bottom topography of the east Australia Sea

A preliminary account of synthetic aperture radar (SAR) imaging mechanisms of oceanic bottom topographic features and a description of the principles of the information extracted from SAR images and the processing and the analysis technology of SAR images are made. Some results were obtained from researching shallow topography and its bathymetric features of the regions of offshore in the east Australia Sea by ERS-1 SAR images. The preliminary research indicates that these features covered with SAR have never been reported before and some results of them are yielded for the first time in Australia. This information is very valuable in a great number of applications to oceanic engineering, shipping navigation, marine fishery and environment, as well as oceanographic research and development. The paper comes to the conclusion that SAR remote sensing of oceanography and its applications are of great potential.

Effect of dexamethasone on intelligence and hearing in preterm infants: a meta-analysis

OBJECTIVE： A meta-analysis of published randomized controlled trials investigating the long- term effect of dexamethasone on the nervous system of preterm infants. DATA SOURCES： Online literature retrieval was conducted using The Cochrane Library （from January 1993 to June 2013）, EMBASE （from January 1980 to June 2013）, MEDLINE （from Janu- ary 1963 to June 2013）, OVID （from January 1993 to June 2013）, Springer （from January 1994 to June 2013） and Chinese Academic Journal Full-text Database （from January 1994 to June 2013）. Key words were preterm infants and dexamethasone in English and Chinese. STUDY SELECTION： Selected studies were randomized controlled trials assessing the effect of intravenous dexamethasone in preterm infants. The quality of the included papers was evaluated and those without the development of the nervous system and animal experiments were exclud- ed. Quality assessment was performed through bias risk evaluation in accordance with Cochrane Handbook 5.1.0 software in the Cochrane Collaboration. The homogeneous studies were analyzed and compared using Revman 5.2.6 software, and then effect model was selected and analyzed. Those papers failed to be included in the meta-analysis were subjected to descriptive analysis. MAIN OUTCOME MEASURES： Nervous system injury in preterm infants. RESULTS： Ten randomized controlled trials were screened, involving 1,038 subjects. Among them 512 cases received dexamethasone treatment while 526 cases served as placebo control group and blank control group. Meta-analysis results showed that the incidence of cerebral palsy, visual im- pairment and hearing loss in preterm infants after dexamethasone treatment within 7 days after birth was similar to that in the control group （RR = 1.47, 95%CI： 0.97-2.21; RR = 1.46, 95%CI： 0.97-2.20; RR = 0.80, 95%CI： 0.54-1.18; P 〉 0.05）, but intelligence quotient was significantly de- creased compared with the control group （MD = -3.55, 95%CI： -6.59 to -0.51; P = 0.02）. Prete rm infants treated with dexamethasone 7 days after birth demonstrated an incidence of cerebral palsy and visual impairment, and changes in intelligence quotient similar to those in the control group （RR = 1.26, 95%CI： 0.89-1.79; RR = 1.37, 95%CI： 0.73-2.59; RR = 0.53, 95%CI： 0.32-0.89; RR = 1.66, 95%CI： -4.7 to 8.01; P 〉 0.05）. However, the incidence of hearing loss was significantly increased compared with that in the control group （RR = 0.53, 95%CI： 0.32-0.89; P = 0.02）. CONCLUSION： Dexamethasone may affect the intelligence of preterm infants in the early stages after birth, but may lead to hearing impairment at later stages after birth. More reliable conclusions should be made through large-size, multi-center, well-designed randomized controlled trials.

Company Profile

Liaoning Dalmond Group （shorten for Dalmond）, established in 2001, is located on Yingkou City with abundant magnesia resource. Through several years struggle, Dalmond develops to an enterprise group holding several company branches.

MET as Program Resources for College English Teaching and Learning：Application and Implications

This paper investigates the current situation of Modern Educational Technology （MET） as program resources for college English teaching, exploring the effectiveness of the integration of MET and language teaching and learning. The case study in this paper illustrates that MET does benefit college English teaching but there are many problems of its application. Pedagogical implications are then provided to enhance the effective integration of MET and language teaching and learning： （1） it is wise for the teachers and learners to reconcile what is desirable with what is acceptable and possible in MET application; （2） teachers should optimize other existing resources to solve the problems caused by inequality and unavailability of MET; （3） teachers should have a clear conception of the relationship of MET and pedagogy to design and apply courseware appropriately; （4） students have beliefs in the benefits of MET, resulting in enhancing their individual language learning and efficiency.

Application of Program Generation Technology in Solving Heat and Flow Problems

Based on a new DIY concept for software development, an automatic program-generating technology attached on a software system called as Finite Element Program Generator （FEPG） provides a platform of developing programs, through which a scientific researcher can submit his special physico-mathematical problem to the system in a more direct and convenient way for solution. For solving flow and heat problems by using finite element method, the stabilization technologies and fraction-step methods are adopted to overcome the numerical difficul- ties caused mainly due to the dominated convection. A couple of benchmark problems are given in this paper as examples to illustrate the usage and the superiority of the automatic program generation technique, including the flow in a lid-driven cavity, the starting flow in a circular pipe, the natural convection in a square cavity, and the flow past a circular cylinder, etc. They are also shown as the verification of the algorithms.

Automatic discovery of stateful variables in network protocol software based on replay analysis

Network protocol software is usually characterized by complicated functions and a vast state space.In this type of program,a massive number of stateful variables that are used to represent the evolution of the states and store some information about the sessions are prone to potentialflaws caused by violations of protocol specification requirements and program logic.Discovering such variables is significant in discovering and exploiting vulnerabilities in protocol software,and still needs massive manual verifications.In this paper,we propose a novel method that could automatically discover the use of stateful variables in network protocol software.The core idea is that a stateful variable features information of the communication entities and the software states,so it will exist in the form of a global or static variable during program execution.Based on recording and replaying a protocol program’s execution,varieties of variables in the life cycle can be tracked with the technique of dynamic instrument.We draw up some rules from multiple dimensions by taking full advantage of the existing vulnerability knowledge to determine whether the data stored in critical memory areas have stateful characteristics.We also implement a prototype system that can discover stateful variables automatically and then perform it on nine programs in Pro FuzzBench and two complex real-world software programs.With the help of available open-source code,the evaluation results show that the average true positive rate(TPR)can reach 82%and the average precision can be approximately up to 96%.

A general introduction to the development of Good Laboratory Practice in China

Good laboratory practice（GLP） plays an important role in pre-clinical studies, which are a key stage in new drug research and development（R＆D）. The development of GLP in China started in the late 1990 s. Following 20 years of developments, GLP system has already been established in this country. This review firstly evaluated all the institutions in this field, and described the annual number and total number of institutions, the distribution of GLP institutions, the types of GLP institutions, and the service provided by these GLP institutions. Since the initiation of the National Key Technology R＆D Program during the 11 th Five-Year Plan, it had a significant effect on the development of GLP. Therefore, the institutions which have undertaken projects from this program will be introduced later. We also described the infrastructure of hardware and software in GLP institutions along with their faults, such as variation in development and the lack of innovation.