Pancreatic Carcinoma with Prominent Mucin Production: A Clinicopathologic and Immunohistochemical Study of 9 Cases

Pancreatic carcinoma occasionally associated with prominent mucin production and this type of tumor designated as PCM (pancreatic carcinoma with prominent mucin production) was diagnosed depends on subjective estimation of the amount of mucous area, and there has been no report on a quantitative evaluation of the amount of mucinous area in the tumor. To examine the feature of PCM, we analyzed 9 cases of PCM among 243 cases of pancreas carcinoma and evaluated the amount of mucin by imaging analysis. Morphologically, 5 cases were classified as intradactal papillary mucinous neoplasms (IPMN)-derived PCM and 4 cases were as ductal adenocarcinoma (DA)-derived PCM. Mucous composition was found to be more than 50% in all IPMN-derived PCM cases, and that was 40% - 50% in DA-derived PCM cases with one exception. IPMN-derived PCM cases showed expansive growth with pancreatic duct dilatation filled with mucin, while DA-derived PCM cases possessed mucin infiltration into interstitial tissue. Immunohisto-chemically, three of 4 DA-derived PCM cases were MUC1(–)/MUC2(+), and the results of expressions for p16 and Dpc4 suggesting that DA-derived PCM was similar to IPMN-derived PCM rather than ordinary DA. Survival rate of DA-derived PCM cases was lower than that of IPMN-derived PCM cases. We advocate that DA-derived PCM may constitute a borderline group between IPMN and ordinary DA.

WANG Cheng-bai(汪承柏)--A Prominent Hepatologist of integrative Medicine

Prof. WANG Cheng-bai, male, was born in Hunan Province, October 1926. He started working as a physician in 1947, and was assigned to Dalian Medical College for further

YAN Yong-qing(严永清)——A Prominent Integrative Pharmacist

YAN Yongqing,male,bornin July 1934 inShanghai,wasgraduated fromthe PharmaceuticsDepartment ofNortheast Pharmaceutical College(Shenyang Phar-maceutical Univer-

Chong-Chet Anterior Scoring Technique for the Correction of Prominent Ears: Results in 30 Patients

A lot ofotoplasty techniques have been developed during the past years. However, there is no single perfect technique which is worldwide accepted. We present our assessment of a Chong-Chet anterior scoring technique for the correction of prominent ears which we applied in 30 patients between 2005 and 2010. This study is a report of creating a natural fold of cartilage using Chong-Chet anterior scoring technique by cartilage incision at the border between the antihelix and scapha, with medial scoring of the scapha and lateral scoring of the antihelix. Sutures were used to maintain the created fold. There were no major complications at the 1-year follow-up evaluation. None of the patients developed a recurrence, or retro protrusion of the helix which required a second operation for correction. The procedure is a simple surgical technique. The reconstructed ear shows reliable results in stability, size and normal convolutions. Furthermore, sharp cartilaginous ridges and hidden helix are avoided.

SUN Yan (孙燕)——A Prominent Oncologist of Internal Medicine

Professor SUN Yan, a famous medical oncologist, was graduated from Yenching University with a B. S. degree in 1951, and from Peking Union Medical College with a M.D. degree in 1956. He studied traditional Chinese medicine from 1960 to 1961, and worked, between 1979 and 1980, as a visiting professor in M. D. Anderson Cancer Center, USA. Since 1959, he has been working in the Department of Medical Oncology in Cancer Hospital of Chinese Academy of Medical Sciences （CAMS）, holding the post of professor ＆ director of Department of Medical Oncology during 1986-1994. He was honored as the ＂Outstanding Physician＂ by CAMS and Peking Union Medical College （PUMC） in 1993, designated as an ＂Advanced Worker＂ in national health care system by the Ministry of Human Affairs in 1994, and elected an academician of Chinese Academy of Engineering in 1999. Since 1991, he has been enjoying the governmental special stipend.

Analysis of Smooth Cepstral Peak Prominence in Hypokinetic Dysarthria Associated With Parkinson’s Disease

Smoothed cepstral peak prominence(CPPs)is a measurement of the distance from the prominent cepstral peak to the linear regression line directly beneath it.Variations of CPPs data acquisition and analysis lead to the complexity of the clinical cut-off values,and there are no agreeable values for a specific voice disorder,such as hypokinetic dysarthria associated with Parkinson’s disease(PD).This study examined the CPPs in people with hypokinetic dysarthria associated with PD compared with healthy participants.Results demonstrated significant differences in speech tasks of sustained vowel and connected speech,with CPPs of connected speech more sensitive to dysphonia and gender difference in PD participants.Males in PD participants presented higher CPPs for sustained vowels and lower CPPs for connected speech than females.It is implied that a consistent clinical application protocol is necessary,and multiple acoustic measures are needed to ensure the accuracy of clinical decisions.

Carving out a Niche African football players feature prominently in the Chinese leagues

The Chinese Football Association Super League （CSL） has broken yet another record. Indeed, the league＇s record recruitment budget of 388 million euros （$342.76 million） yeas broken this season. In 2018, more than 470 million euros （$415.19 million） have been spent on retaining the best football stars that have come to China in recent years, as well as on attracting even more talented footballers.

A Cognitive Study of the Naming Elements of Chinese Dish Names Based on the Prominence Principle

The assortedness of Chinese food,together with the complexity of their naming elements,has ignited numerous scholars' interests in this field and prompted them to make abundant analyses of Chinese dish names.Most of them,however,were done in studies of traditional linguistics,rhetoric,translatology and cross-cultural communication.And studies,based on corpus,on the naming elements of Chinese dishes under cognitive linguistic theories almost remain a blank.This paper aims to conduct a quantitative analysis of 4,000 Chinese dish names(500 ones selected freely from each of the eight cuisines),based on the Prominence Principle,in order to identify the specific naming elements of Chinese dishes and forward related statistics and ratios.

Unusually Broadened Spectral Profiles Observed in Solar Prominences

After surveying the spectra of 39 prominences observed by the Multi-channel Infrared Solar Spectrograph at Purple Mountain Observatory and the 25 cm coronagraph at the Norikura Solar Observatory, we found that about 28% of them show small spatial scale (6''–8'') and short time scale (tens of seconds to a few minutes), unusual large broadening and large shift velocities in spectral lines including Hα, Hβ, H, Ca II H, Ca II K, Ca II 8542?, He I D3 and He I 10830?. We present in detail two typical events observed respectively on 2002 May 27 and 1981 August 2. The full-width at half maximum of the widest profile of the 2001 prominence is 1.8? for Hα and 2.9 ? for He I 10830?, while that of the 1981 prominence is 5.3 ? for Hβ, 3.6 ? for Ca II K, 4.0 ? for Ca II H and 2.8 ? for He I D3. Such broadenings generally occur at a level of several-thousand kilometres above the chromosphere. Further, most of these prominences manifest a rotation of (0.4–1.35)×10-2 rads s?1 pointing to the Sun and large line-of-sight velocities of 20–200 km s?1. Some of these events correspond in time to an enhancement or a small peak in the GOES X-ray flux, indicating the existence of high energy process at work. These prominences generally display discernible changes in the Hα morphology around the time of large broadening, but do not show Hα brightening or overall eruption except for a few small surge-like events, hence, they are hardly observed in daily Hα patrols. According to the characteristics of their Hα structures and spectral properties, we infer these events are small-scale eruptions similar to nano-flares, which may contribute to the mass and energy transported into the corona. Large turbulent velocities of 25–120 km s?1 are responsible for the observed broadenings.

The Ultrastructural Characteristics of the Stria Vascularis, Spiral Prominence and Spiral Ligament in Guinea Pigs

The mean length of the stria vascularis (SV) and the basilar membrane of four normalguinea pigs measured by means of surface preparation was 21.11 mm and 19. 90 mm respectively,and the mean width of their apical turns of SV and the turns of the cochlear basis was 0. 44 mmand 0. 86 mm respectively. The ultrastructure of SV, spiral ligament (SL) and spiral prominence(SP) of both ears of eight guinea pigs were observed by scanning electron microscopy(SEM) andtransmission electron microsoopy(TEM). There were a large number of coated vesicles in thesupranuclear region of SV, some opened to the endolymph. A great number of folding cytoplasmicprojections were filled with small vesicles The capillary network was extremely rich indicating thatthe endolymph could be secreted and absorbed by SV. The cellular conjunction in the SV. SL andSP formed an effective barrier. It has not been proved in this study that the melanin offers resistanceto acoustic stimulation.

Derivation of the Spiral Motion of an Eruptive Prominence and Its Explanation

A 2D velocity field of the eruptive prominence （EP） of 1991 March 5 is obtained from its spectral data observed at the Yunnan Observatory and the velocity distributions along the entrance slit are derived for different observing frames. Under the assumption that matter in the EP undergoes axial, radial and possible rotational motions, we construct a theoretical velocity distribution of the EP along the entrance slit, to derive, by fitting, the angular velocity of rotation ω and the other three parameters （axial velocity v0, radial velocity vr and the angle between the EP plane and the line of sight Ф）. We found： an averaged angular velocity ω of 3.0 × 10^-3 arc s^-1 and the variation of ω with the height above the solar limb. As the EP rises, the matter within it in fact moves along a spiral path around its axis. The spiral motion may be explained by the theory of plasma ‘double pole diffusion＇ （DPD） caused by a sharp density gradient between the eruptive prominence and the surrounding corona. A theoretical angular velocity ω′ is estimated based on the DPD and basically coincides with ω obtained from the optimal velocity fitting.

Damped large amplitude oscillations in a solar prominence and a bundle of coronal loops

We investigate the evolutions of two prominences （P1, P2） and two bundles of coronal loops （L1, L2）, observed with SDO/AIA near the east solar limb on 2012 September 22. It is found that there were large-amplitude oscillations in P1 and L1 but no detectable motions in P2 and L2. These transverse oscillations were triggered by a large-scale coronal wave, originating from a large flare in a remote active region behind the solar limb. By carefully comparing the locations and heights of these oscillating and non-oscillating structures, we conclude that the propagating height of the wave is between 50 Mm and 130 Mm. The wave energy deposited in the oscillating prominence and coronal loops is at least of the order of 10-8 erg. Furthermore, local magnetic field strength and Alfv6n speeds are derived from the oscillating periods and damping time scales, which are extracted from the time series of the oscillations. It is demon- strated that oscillations can be used in not only coronal seismology, but also to reveal the properties of the wave.

Prominence Activity during the 2006 Total Solar Eclipse

During total solar eclipses, we can observe the outer atmospheric layers of the sun (chromosphere and corona). The solar corona extends to several solar radii depending on the sunspot cycle. Basic coronal structures such as polar streamers, helmet type structures were?observed?during the 2006 total solar eclipse. Our total solar eclipse 2006 observations through?both White light corona and H-Alpha filter allowed us to describe coronal structures and Prominence Activity. We found that the solar corona is extended to 4 times of solar radii, the existence different zones of white light corona were shown, moreover, we compared the defined features of solar corona at different observing locations along the track of total solar eclipse 2006. The solar limb activity was studied during both of partial and total eclipse phases by using H-Alpha and white light observations from Salloum, Egypt. We got same prominence activity during partial and total phases of the solar eclipse and recorded three prominences on solar limb. Finally, our processed image in a good agreement with the published?processed images?was?observed from different locations along the track of total eclipse,?added, similar magnetic field structure shown in our processed image and published one.

GUO Sai-shan (郭赛珊)——Prominant Internist and Diabetics Specialist

GUO Sai-shan was born on October 24, 1938, in Putian Fujian Province, 1960 graduated in Shanghai First Medical College （now Shanghai Medical University）. At present, she is the Professor of Peking Union Medical College. Chief Doctor,Post-doctorate Tutor, in 1991 to 2002 she was appointed as Director of Department of Traditional Chinese Medicine （TOM）;

High-resolution observations of prominence plume formation with the new vacuum solar telescope

Prominence plumes are evacuated upflows that emerge from bubbles below prominences,whose formation mechanism is still unclear.Here we present a detailed study of plumes in a quiescent prominence using the high-resolution Hαfiltergrams at the line center as well as line wing at±0.4 A from the New Vacuum Solar Telescope.Enhancements of brightening,blue shifts,and turbulence at the fronts of plumes are found during their formation.Some large plumes split at their heads and finger-shaped structures are formed between them.Blue-shifted flows along the bubble-prominence interface are found before and during the plume formation.Our observations are consistent with the hypothesis that prominence plumes are related to coupled Kelvin-Helmholtz and Rayleigh-Taylor(KH/RT)instabilities.Plume splittings and fingers are evidence of RT instability,and the flows may increase the growth rate of KH/RT instabilities.However,the significant turbulence at plume fronts may suggest that the RT instability is triggered by the plumes penetrating into the prominence.In this scenario,extra mechanisms are necessary to drive the plumes.

“Malaysia Has Certainly Benefited from China’s Prominence on the World Stage”——Exclusive Interview with See Chee Kong Leonard, Business Minister of Embassy of Malaysia in PRC

Relations between China and Malaysia have been developing steadily.Recently,See Chee Kong Leonard,Business Minister of Embassy of Malaysia in PRC,accepted an interview with Chinas Foreign Tradey and talked about the 45 years of economic and trade cooperation and achievements of the two countries.

Contrastive Study of English and Chinese Subjects in Perspective of Cognitive Prominence

This present paper, in perspective of cognitive prominence, the cognitive motive on the differences between English and Chinese subjects, and then explores the interpretability of the Adaptation Theory in translating the subjects. It is discovered that the blending of the cognitive prominence and the theory of adaptation is very effective in elaborating the subtle differences of English and Chinese subjects in translation, and reasonable in expounding the infeasibility of some plausible versions.

Machine learning identifies prominent factors associated with cardiovascular disease:findings from two million adults in the Kashgar Prospective Cohort Study(KPCS)

Background:Identifying factors associated with cardiovascular disease(CVD)is critical for its prevention,but this topic is scarcely investigated in Kashgar prefecture,Xinjiang,northwestern China.We thus explored the CVD epidemi-ology and identified prominent factors associated with CVD in this region.Methods:A total of 1,887,710 adults at baseline(in 2017)of the Kashgar Prospective Cohort Study were included in the analysis.Sixteen candidate factors,including seven demographic factors,4 lifestyle factors,and 5 clinical factors,were collected from a questionnaire and health examination records.CVD was defined according to International Clinical Diagnosis(ICD-10)codes.We first used logistic regression models to investigate the association between each of the candidate factors and CVD.Then,we employed 3 machine learning methods-Random Forest,Random Ferns,and Extreme Gradient Boosting-to rank and identify prominent factors associated with CVD.Stratification analyses by sex,ethnicity,education level,economic status,and residential setting were also performed to test the consistency of the ranking.Results:The prevalence of CVD in Kashgar prefecture was 8.1%.All the 16 candidate factors were confirmed to be significantly associated with CVD(odds ratios ranged from 1.03 to 2.99,all p values<0.05)in logistic regression models.Further machine learning-based analysis suggested that age,occupation,hypertension,exercise frequency,and dietary pattern were the five most prominent factors associated with CVD.The ranking of relative importance for prominent factors in stratification analyses showed that the factor importance generally followed the same pattern as that in the overall sample.Conclusions:CVD is a major public health concern in Kashgar prefecture.Age,occupation,hypertension,exercise frequency,and dietary pattern might be the prominent factors associated with CVD in this region.In the future,these factors should be given priority in preventing CVD in future.