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Protein hydrolysates in animal nutrition:Industrial production, bioactive peptides,and functional significance 被引量:23
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作者 Yongqing Hou Zhenlong Wu +2 位作者 Zhaolai Dai Genhu Wang Guoyao Wu 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2017年第3期513-525,共13页
Recent years have witnessed growing interest in the role of peptides in animal nutrition. Chemical, enzymatic, or microbial hydrolysis of proteins in animal by-products or plant-source feedstuffs before feeding is an ... Recent years have witnessed growing interest in the role of peptides in animal nutrition. Chemical, enzymatic, or microbial hydrolysis of proteins in animal by-products or plant-source feedstuffs before feeding is an attractive means of generating high-quality small or large peptides that have both nutritional and physiological or regulatory functions in livestock, poultry and fish. These peptides may also be formed from ingested proteins in the gastrointestinal tract, but the types of resultant peptides can vary greatly with the physiological conditions of the animals and the composition of the diets. In the small intestine, large peptides are hydrolyzed to small peptides,which are absorbed into enterocytes faster than free amino acids(AAs) to provide a more balanced pattern of AAs in the blood circulation. Some peptides of plant or animal sources also have antimicrobial, antioxidant,antihypertensive, and immunomodulatory activities. Those peptides which confer biological functions beyond their nutritional value are called bioactive peptides. They are usually 2–20 AA residues in length but may consist of 〉20AA residues. Inclusion of some(e.g. 2–8%) animal-protein hydrolysates(e.g., porcine intestine, porcine mucosa,salmon viscera, or poultry tissue hydrolysates) or soybean protein hydrolysates in practical corn-and soybean mealbased diets can ensure desirable rates of growth performance and feed efficiency in weanling pigs, young calves,post-hatching poultry, and fish. Thus, protein hydrolysates hold promise in optimizing the nutrition of domestic and companion animals, as well as their health(particularly gut health) and well-being. 展开更多
关键词 Animals nutrition Peptides protein hydrolysates Sustainability
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New development of whey protein products as nutritional food ingredients
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作者 Chao Wu(Hilmar Ingredients) 《中国食品添加剂》 CAS 北大核心 2009年第S1期275-279,共5页
Whey protein products provided ideal ingredients for nutritional food applications.Whey proteins are known to have high nutritional quality due to their high content of essential amino acids,high digestibility and bio... Whey protein products provided ideal ingredients for nutritional food applications.Whey proteins are known to have high nutritional quality due to their high content of essential amino acids,high digestibility and biological value.Research in the past decades has shown that many of the whey protein fractions and peptides derived from them possess various biological activities.The technology developments in the last decade,such as those in the areas of protein fractionation technologies have made industrial scale production of fractionated whey protein products commercially feasible.The development in hydrolysis technology and the peptide analytical capability allowed production of whey protein hydrolysates with designed bioactivity and functionalities.People are continuously finding new biological activities of the various whey protein fractions or their hydrolysis products.Significant amount of research has also been carried out to study the clinical benefits of some of the whey protein fractions and whey protein derived peptides.Examples of these studies will be reviewed and discussed. 展开更多
关键词 New development of whey protein products as nutritional food ingredients
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体外模拟消化在水产品营养活性物质研究中的应用进展 被引量:3
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作者 矫春娜 张健 +5 位作者 刘芳 王共明 陈建强 井月欣 刘昕 赵云苹 《食品工业科技》 CAS 北大核心 2023年第8期421-428,共8页
食物营养素对人体健康的影响主要取决于胃肠道内的消化过程。体外模拟消化可以综合模拟人体消化过程,具有重现性好、简单灵活、应用广泛等优点,不仅可以预测食物成分、结构和消化特性之间的关系,还可以评估食物成分的生物利用度和消化... 食物营养素对人体健康的影响主要取决于胃肠道内的消化过程。体外模拟消化可以综合模拟人体消化过程,具有重现性好、简单灵活、应用广泛等优点,不仅可以预测食物成分、结构和消化特性之间的关系,还可以评估食物成分的生物利用度和消化代谢物对人体健康的影响,是研究食品中营养物质的有效工具。体外模拟消化已经广泛用于水产品营养活性成分的研究,本文综述了体外模拟消化模型的现状,对静态模型和动态模型的优缺点及其应用进行了详细描述,并系统总结了体外模拟消化在研究水产品蛋白质消化率、生物活性肽消化稳定性、多糖消化酵解特性及脂质氧化稳定性等方面的应用。此外,还对体外模拟消化模型的局限和优化提出了建议,以期对其在海洋生物医药、海洋功能食品等领域的应用有所助益。 展开更多
关键词 体外模拟消化 水产品 营养活性物质 蛋白质 活性肽 多糖 脂质
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Challenges facing sustainable protein production:Opportunities for cereals 被引量:1
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作者 Luqman B.Safdar MJohn Foulkes +4 位作者 Friedrich H.Kleiner Iain R.Searle Rahul A.Bhosale Ian D.Fisk Scott A.Boden 《Plant Communications》 SCIE CSCD 2023年第6期55-69,共15页
Rising demands for protein worldwide are likely to drive increases in livestock production,asmeat provides-40%of dietary protein.This will come at a significant environmental cost,and a shift toward plant-based protei... Rising demands for protein worldwide are likely to drive increases in livestock production,asmeat provides-40%of dietary protein.This will come at a significant environmental cost,and a shift toward plant-based protein sources would therefore provide major benefits.While legumes provide substantial amounts of plant-based protein,cereals are the major constituents of global foods,with wheat alone accounting for 15–20%of the required dietary protein intake.Improvement of protein content in wheat is limited by phenotyping challenges,lack of genetic potential of modern germplasms,negative yield trade-offs,and environmental costs of nitrogen fertilizers.Presenting wheat as a case study,we discuss how increasing protein content in cereals through a revised breeding strategy combined with robust phenotyping could ensure a sustainable protein supply while minimizing the environmental impact of nitrogen fertilizer. 展开更多
关键词 SUSTAINABILITY protein nutrition grain protein content innovative breeding
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微波消解-分光光度法测定乳清蛋白营养强化粉中磷的含量 被引量:1
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作者 伍丽珍 刘慧堂 +1 位作者 邱桃妍 陈均洪 《食品安全质量检测学报》 CAS 2020年第23期8676-8680,共5页
目的建立微波消解-分光光度法测定乳清蛋白营养强化粉中磷含量的测定方法。方法乳清蛋白营养强化粉中加入硝酸于石墨消解仪中预消解,待冷却后加入30%过氧化氢使用微波消解仪消解,样品经过赶酸,转移至容量瓶中并定容至刻度,在稀释液中加... 目的建立微波消解-分光光度法测定乳清蛋白营养强化粉中磷含量的测定方法。方法乳清蛋白营养强化粉中加入硝酸于石墨消解仪中预消解,待冷却后加入30%过氧化氢使用微波消解仪消解,样品经过赶酸,转移至容量瓶中并定容至刻度,在稀释液中加入钒钼酸铵试剂后使用紫外可见分光光度计进行检测。结果磷在浓度2~15μg/mL之间呈现良好的线性关系,r2=0.9997,回收率为95.00%~101.20%,相对标准偏差为2.0%。结论该方法操作简便、准确、安全、重现性好,能准确测定乳清蛋白营养强化粉中磷含量。 展开更多
关键词 乳清蛋白 营养强化粉 微波消解法 分光光度法
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大柴胡汤通过CREB/PGC-1α通路保护营养型肥胖大鼠肝脏粒体功能 被引量:7
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作者 李龙春 李晓晔 +1 位作者 杜小华 柴铁劬 《中国实验方剂学杂志》 CAS CSCD 北大核心 2021年第9期26-31,共6页
目的:观察大柴胡汤对营养型肥胖大鼠环磷腺苷效应元件结合蛋白(CREB)/过氧化物酶体增殖物激活受体γ共激活因子α(PGC-1α)通路的作用及肝脏线粒体的保护机制。方法:8周龄SD雄性大鼠120只,随机分为正常组20只和造模组100只。正常组给予... 目的:观察大柴胡汤对营养型肥胖大鼠环磷腺苷效应元件结合蛋白(CREB)/过氧化物酶体增殖物激活受体γ共激活因子α(PGC-1α)通路的作用及肝脏线粒体的保护机制。方法:8周龄SD雄性大鼠120只,随机分为正常组20只和造模组100只。正常组给予大鼠维持饲料喂养,造模组给予高脂饲料喂养。造模成功大鼠随机分为模型组、阳性药(二甲双胍)组、大柴胡汤低、中、高剂量组(4.25,8.5,17 g·kg^(-1)),每组20只。电子天平称取并比较各组大鼠体质量,计算Lee’s指数,分光光度法检测肝脏线粒体膜电位,电镜检测线粒体超微结构,蛋白免疫印迹法检测PGC-1α蛋白表达和CREB磷酸化作用。结果:与正常组比较,模型组大鼠体质量及Lee’s指数显著增加(P<0.01),线粒体膜电位显著下降,PGC-1α蛋白表达和CREB磷酸化水平显著下降(P<0.01);与模型组比较,大柴胡汤能够明显降低肥胖大鼠体质量和Lee’s指数(P<0.05,P<0.01),提高肝脏线粒体膜电位(P<0.05,P<0.01)和保护线粒体结构完整性,上调PGC-1α蛋白表达和促进CREB磷酸化(P<0.05,P<0.01)。结论:大柴胡汤激活CREB/PGC-1α通路,保护线粒体结构与功能,有效抑制肥胖大鼠体质量增加。 展开更多
关键词 大柴胡汤 营养性肥胖大鼠 线粒体 环磷腺苷效应元件结合蛋白(CREB)/过氧化物酶体增殖物激活受体γ共激活因子α(PGC-1α)通路
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