A Smart resistance thermometer sensor is designed to overcome the shortages of the traditional ones, and Con-form to the world development trend of the sensor market.According to the constitutions of this Smart sensor...A Smart resistance thermometer sensor is designed to overcome the shortages of the traditional ones, and Con-form to the world development trend of the sensor market.According to the constitutions of this Smart sensor and its application coverage,those parts with good -application and low-cost were chosen to constitute this sensor on the basis of full consideration of the linkage among every part.The whole testing system were controlled and processed by C8051F350 single-chip,it could measure precise temperature by PT100 resistance thermometer and circumstance temperature for temperature compensating automatically and simultane-ously,it also could amplify signals to convert analog signals to digital ones,and display results automatically by analysing and processing information.Furthermore,it could auto-compensate self-check,and spot communicate.展开更多
Platinum(Pt) based drugs, such as cisplatin, are widely used as anti-cancer agents, but their severe adverse reactions and resistance of cancer patients have limited their board clinical use. For the last few decades,...Platinum(Pt) based drugs, such as cisplatin, are widely used as anti-cancer agents, but their severe adverse reactions and resistance of cancer patients have limited their board clinical use. For the last few decades, Pt(Ⅱ) compounds, Pt(Ⅳ) prodrugs as well as smart drug delivery systems have been developed to overcome these problems. However, most conventional strategies rely on the similar anti-cancer mechanism with cisplatin and consequently only achieve limited success. Recently, Pt nanocrystals/nanoclusters(Pt NCs), with a brand new anti-cancer mechanism, have shown a promising potential in targeted cancer therapy, especially in Pt resistance circumvention. This review is helpful to understand the research strategies of Pt drugs, particularly, the recent developments and medical applications of Pt NCs.展开更多
文摘A Smart resistance thermometer sensor is designed to overcome the shortages of the traditional ones, and Con-form to the world development trend of the sensor market.According to the constitutions of this Smart sensor and its application coverage,those parts with good -application and low-cost were chosen to constitute this sensor on the basis of full consideration of the linkage among every part.The whole testing system were controlled and processed by C8051F350 single-chip,it could measure precise temperature by PT100 resistance thermometer and circumstance temperature for temperature compensating automatically and simultane-ously,it also could amplify signals to convert analog signals to digital ones,and display results automatically by analysing and processing information.Furthermore,it could auto-compensate self-check,and spot communicate.
基金supported by the National Key Research and Development Program of China(2016YFA0203600)the National Natural Science Foundation of China(51503180,5161101036)+1 种基金“Thousand Talents Program”for Distinguished Young Scholars(588020*G81501/048)Fundamental Research Funds for the Central Universities(520002*172210161)
文摘Platinum(Pt) based drugs, such as cisplatin, are widely used as anti-cancer agents, but their severe adverse reactions and resistance of cancer patients have limited their board clinical use. For the last few decades, Pt(Ⅱ) compounds, Pt(Ⅳ) prodrugs as well as smart drug delivery systems have been developed to overcome these problems. However, most conventional strategies rely on the similar anti-cancer mechanism with cisplatin and consequently only achieve limited success. Recently, Pt nanocrystals/nanoclusters(Pt NCs), with a brand new anti-cancer mechanism, have shown a promising potential in targeted cancer therapy, especially in Pt resistance circumvention. This review is helpful to understand the research strategies of Pt drugs, particularly, the recent developments and medical applications of Pt NCs.
