This study investigated whether the curative effect of short-pulse gastric electrical stimulation （GES） on the vasopressin-induced dyspeptic symptoms was mediated by central opioid peptide-producing neurons. Five fe...This study investigated whether the curative effect of short-pulse gastric electrical stimulation （GES） on the vasopressin-induced dyspeptic symptoms was mediated by central opioid peptide-producing neurons. Five female beagle dogs implanted with 1 pair of electrodes in gastric serosa were used in a two-experiment study. In experiment one, the brain was scanned by positron emission tomography in 3 dogs with and without short-pulse GES, and the radioactivity in nuclei of solitary tract （NST） and hypothalamus was detected. Experiment two was composed of 4 sessions. In session one, the dogs were injected with vasopressin in the absence of short-pulse GES. With session two, the short-pulse GES was simultaneously given via the electrodes with the injection of vasopressin. In sessions three and four, naloxone and naloxone methiodide was administered respectively in the presence of short-pulse GES. Motion sickness-like symptoms were scored and compared among the different sessions. The results showed that the short-pulse GES significantly increased the radioactivity in NST and hypothalamic nuclei （P〈0.05, vs control）. The short-pulse GES could ameliorate the vasopressin-induced motion sickness-like symptoms in dogs. Naloxone, but not naloxone methiodide could attenuate the curative effects of short-pulse GES. It is concluded that NST and hypothalamic nuclei may participate in the mediation of the curative effects of short-pulse GES on dyspepsia-like symptoms. Central opioid peptide-containing neurons presumably mediate the therapeutic effect on dyspeptic symptoms of short-pulse GES.展开更多
The American Oil Chemists’ Society(AOCS) is a volunteer-led association. AOCS develops and publishes methods of analysis for fats, oils, proteins, surfactants, and related materials according to accepted internationa...The American Oil Chemists’ Society(AOCS) is a volunteer-led association. AOCS develops and publishes methods of analysis for fats, oils, proteins, surfactants, and related materials according to accepted international standards to ensure equitable trade practices on a global scale. AOCS Official Method development has been going on for over a hundred years. The founding vision of AOCS in 1909 was "an organization designed for the development and advancement of analytical methods for cottonseed products." AOCS Official Methods are essential to world trade and are used to confirm the value of billions of pounds of oilseed-based commodities and finished products each year. In addition, AOCS conducts proficiency testing, provides certified reference materials, and collaborates with other standards developers including the International Organization for Standardization(ISO) and the Codex Alimentarius Commission. AOCS serves as a professional scientific membership organization providing current and emerging information as well as disseminating research results in oils, fats, lipids, proteins, surfactants, and related materials. Several avenues are used, especially meetings, publications, interest groups, networking opportunities, and web presence. Many scientists, experts, and others engaged in working in these fields find their professional "home" in AOCS. The AOCS Technical Leadership Committee comprises some of the most experienced AOCS members and scientists. The AOCS Technical Services department staff relies on this committee for guidance on scientific matters and for advice in prioritizing the opportunities facing AOCS.展开更多
This paper introduces a reference-pulse interpolator motion control system, which can be applied for computer numerical control (CNC) machine tools. The interpolation is calculated in DSP and the independent pulse gen...This paper introduces a reference-pulse interpolator motion control system, which can be applied for computer numerical control (CNC) machine tools. The interpolation is calculated in DSP and the independent pulse generator modules are performed in FPGA, which can generate precise reference velocity profile and eliminate the path error of reference pulse interpolation. The proposed methodology has many advantages over existing reference-pulse interpolator controller, such as: real-time, extensibility, high flexibility and high precision motion profile planning.展开更多
Continuous-variable quantum key distribution (CVQKD) with the local local oscillator (LLO) is confronted with new security problems due to the reference pulses transmitted together with quantum signals over the insecu...Continuous-variable quantum key distribution (CVQKD) with the local local oscillator (LLO) is confronted with new security problems due to the reference pulses transmitted together with quantum signals over the insecure quantum channel. In this paper, we propose a method of phase attack on reference pulses of the LLO-CVQKD with time-multiplexing. Under this phase attack, the phase drifts of reference pulses are manipulated by eavesdroppers, and then the phase compensation error is increased. Consequently, the secret key rate is reduced due to the imperfect phase compensation for quantum signals. Based on the noise model of imperfect phase compensation, the practical security of LLO-CVQKD under phase attack is analyzed. The simulation results show that the practical security is reduced due to the phase attack, yet it is still tight when system parameters are estimated by training signals.展开更多
The theories of synchronization based on secure communications using digital chaos are presented. A new synchronous method-cycles-interval Pulse drive is developed and realized. Experimental results show it is availab...The theories of synchronization based on secure communications using digital chaos are presented. A new synchronous method-cycles-interval Pulse drive is developed and realized. Experimental results show it is available, and in order to reduce synchronous noise, a method using model references solves the ratio of signal power to noise power, so the secure communication system can be realized.展开更多
Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson＇s disease. Programming of the stimulation parameters is important for maintaining th...Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson＇s disease. Programming of the stimulation parameters is important for maintaining the efficacy of deep brain stimulation. Voltage is consid- ered to be the most effective programming parameter. The present study is a retrospective analysis of six patients with Parkinson＇s disease （four men and two women, aged 37-65 years）, who underwent bilateral deep brain stimulation of the subthalamic nucleus at the First Affiliated Hospital of Sun Yat-sen University, China, and who subsequently adjusted only the stimulation voltage. We evaluated motor symptom severity using the Unified Parkinson＇s Disease Rating Scale Part III, symptom progression using the Hoehn and Yahr scale, and the levodopa equivalent daily dose, before surgery and 1 and 2 years after surgery. The 2-year follow-up results show that rigidity and tremor improved, and clinical symptoms were reduced, while pulse width was maintained at 60 ps and frequency at 130 Hz. Voltage adjust- ment alone is particularly suitable for patients who cannot tolerate multiparameter program adjustment. Levodopa equivalent daily dose was markedly reduced 1 and 2 years after surgery compared with baseline. Our results confirm that rigidity, tremor and bradykinesia can be best alleviated by voltage adjustment. The trial was registered at ClinicalTrials.gov （identifier： NCT01934881）.展开更多
基金supported by a grant from the National Natural Sciences Foundation of China (No 30500233)
文摘This study investigated whether the curative effect of short-pulse gastric electrical stimulation （GES） on the vasopressin-induced dyspeptic symptoms was mediated by central opioid peptide-producing neurons. Five female beagle dogs implanted with 1 pair of electrodes in gastric serosa were used in a two-experiment study. In experiment one, the brain was scanned by positron emission tomography in 3 dogs with and without short-pulse GES, and the radioactivity in nuclei of solitary tract （NST） and hypothalamus was detected. Experiment two was composed of 4 sessions. In session one, the dogs were injected with vasopressin in the absence of short-pulse GES. With session two, the short-pulse GES was simultaneously given via the electrodes with the injection of vasopressin. In sessions three and four, naloxone and naloxone methiodide was administered respectively in the presence of short-pulse GES. Motion sickness-like symptoms were scored and compared among the different sessions. The results showed that the short-pulse GES significantly increased the radioactivity in NST and hypothalamic nuclei （P〈0.05, vs control）. The short-pulse GES could ameliorate the vasopressin-induced motion sickness-like symptoms in dogs. Naloxone, but not naloxone methiodide could attenuate the curative effects of short-pulse GES. It is concluded that NST and hypothalamic nuclei may participate in the mediation of the curative effects of short-pulse GES on dyspepsia-like symptoms. Central opioid peptide-containing neurons presumably mediate the therapeutic effect on dyspeptic symptoms of short-pulse GES.
文摘The American Oil Chemists’ Society(AOCS) is a volunteer-led association. AOCS develops and publishes methods of analysis for fats, oils, proteins, surfactants, and related materials according to accepted international standards to ensure equitable trade practices on a global scale. AOCS Official Method development has been going on for over a hundred years. The founding vision of AOCS in 1909 was "an organization designed for the development and advancement of analytical methods for cottonseed products." AOCS Official Methods are essential to world trade and are used to confirm the value of billions of pounds of oilseed-based commodities and finished products each year. In addition, AOCS conducts proficiency testing, provides certified reference materials, and collaborates with other standards developers including the International Organization for Standardization(ISO) and the Codex Alimentarius Commission. AOCS serves as a professional scientific membership organization providing current and emerging information as well as disseminating research results in oils, fats, lipids, proteins, surfactants, and related materials. Several avenues are used, especially meetings, publications, interest groups, networking opportunities, and web presence. Many scientists, experts, and others engaged in working in these fields find their professional "home" in AOCS. The AOCS Technical Leadership Committee comprises some of the most experienced AOCS members and scientists. The AOCS Technical Services department staff relies on this committee for guidance on scientific matters and for advice in prioritizing the opportunities facing AOCS.
文摘This paper introduces a reference-pulse interpolator motion control system, which can be applied for computer numerical control (CNC) machine tools. The interpolation is calculated in DSP and the independent pulse generator modules are performed in FPGA, which can generate precise reference velocity profile and eliminate the path error of reference pulse interpolation. The proposed methodology has many advantages over existing reference-pulse interpolator controller, such as: real-time, extensibility, high flexibility and high precision motion profile planning.
文摘Continuous-variable quantum key distribution (CVQKD) with the local local oscillator (LLO) is confronted with new security problems due to the reference pulses transmitted together with quantum signals over the insecure quantum channel. In this paper, we propose a method of phase attack on reference pulses of the LLO-CVQKD with time-multiplexing. Under this phase attack, the phase drifts of reference pulses are manipulated by eavesdroppers, and then the phase compensation error is increased. Consequently, the secret key rate is reduced due to the imperfect phase compensation for quantum signals. Based on the noise model of imperfect phase compensation, the practical security of LLO-CVQKD under phase attack is analyzed. The simulation results show that the practical security is reduced due to the phase attack, yet it is still tight when system parameters are estimated by training signals.
基金This work was financially supported by the National Nature Science Foundation of China (No. 69772014)
文摘The theories of synchronization based on secure communications using digital chaos are presented. A new synchronous method-cycles-interval Pulse drive is developed and realized. Experimental results show it is available, and in order to reduce synchronous noise, a method using model references solves the ratio of signal power to noise power, so the secure communication system can be realized.
基金supported by the Science and Technology Foundation of Guangdong Province of China,No.2014A030304019the Natural Science Foundation of Guangdong Province of China,No.2015A030313164
文摘Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson＇s disease. Programming of the stimulation parameters is important for maintaining the efficacy of deep brain stimulation. Voltage is consid- ered to be the most effective programming parameter. The present study is a retrospective analysis of six patients with Parkinson＇s disease （four men and two women, aged 37-65 years）, who underwent bilateral deep brain stimulation of the subthalamic nucleus at the First Affiliated Hospital of Sun Yat-sen University, China, and who subsequently adjusted only the stimulation voltage. We evaluated motor symptom severity using the Unified Parkinson＇s Disease Rating Scale Part III, symptom progression using the Hoehn and Yahr scale, and the levodopa equivalent daily dose, before surgery and 1 and 2 years after surgery. The 2-year follow-up results show that rigidity and tremor improved, and clinical symptoms were reduced, while pulse width was maintained at 60 ps and frequency at 130 Hz. Voltage adjust- ment alone is particularly suitable for patients who cannot tolerate multiparameter program adjustment. Levodopa equivalent daily dose was markedly reduced 1 and 2 years after surgery compared with baseline. Our results confirm that rigidity, tremor and bradykinesia can be best alleviated by voltage adjustment. The trial was registered at ClinicalTrials.gov （identifier： NCT01934881）.
