BACKGROUND Pulse oximetry has become a cornerstone technology in healthcare,providing non-invasive monitoring of oxygen saturation levels and pulse rate.Despite its widespread use,the technology has inherent limitatio...BACKGROUND Pulse oximetry has become a cornerstone technology in healthcare,providing non-invasive monitoring of oxygen saturation levels and pulse rate.Despite its widespread use,the technology has inherent limitations and challenges that must be addressed to ensure accurate and reliable patient care.AIM To comprehensively evaluate the advantages,limitations,and challenges of pulse oximetry in clinical practice,as well as to propose recommendations for optimizing its use.METHODS A systematic literature review was conducted to identify studies related to pulse oximetry and its applications in various clinical settings.Relevant articles were selected based on predefined inclusion and exclusion criteria,and data were synthesized to provide a comprehensive overview of the topic.RESULTS Pulse oximetry offers numerous advantages,including non-invasiveness,real-time feedback,portability,and costeffectiveness.However,several limitations and challenges were identified,including motion artifacts,poor peripheral perfusion,ambient light interference,and patient-specific factors such as skin pigmentation and hemoglobin variants.Recommendations for optimizing pulse oximetry use include technological advancements,education and training initiatives,quality assurance protocols,and interdisciplinary collaboration.CONCLUSION Pulse oximetry is crucial in modern healthcare,offering invaluable insights into patients’oxygenation status.Despite its limitations,pulse oximetry remains an indispensable tool for monitoring patients in diverse clinical settings.By implementing the recommendations outlined in this review,healthcare providers can enhance the effectiveness,accessibility,and safety of pulse oximetry monitoring,ultimately improving patient outcomes and quality of care.展开更多
Peripheral oxygenation level (SpO<sub>2</sub>) can provide vital information on body functions. Continuous monitoring facilitates effective diagnosis and treatment and can even be lifesaving. Clinical devi...Peripheral oxygenation level (SpO<sub>2</sub>) can provide vital information on body functions. Continuous monitoring facilitates effective diagnosis and treatment and can even be lifesaving. Clinical device monitor SpO<sub>2</sub> using a clip, and measure light transmission through the tissue. This method limits the body locations of the clip’s placement and is sensitive to body movement, which hampers continuous SpO<sub>2</sub> monitoring during wakefulness or sleep, thus decreasing its usability in clinics and its accessibility in homecare usage. We developed a portable, wireless, flat and low cost prototype for continuous monitoring of SpO<sub>2</sub> that overcomes those limitations. The prototype enables convenient measurement in larger variety of body locations by spectrophotometric measurements of changes in the optical reflectance unlike other device that measure absorption through the tissue. The original design and signal processing enable reliable signal acquisition, synchronization and control. An Android’s application was developed to provide a user friendly interface for results display on smartphones. The prototype’s measurements were compared to commercial device that simultaneously measured heart rate frequency, transcutaneous oxygen tension (tcPO<sub>2</sub>) and SpO<sub>2</sub>. The prototype’s measurements accurately reflected changes caused by blood pulses, were correlated to the heart rate, and were sensitive to changes in oxygen saturation. Excellent real time behavior and synchronization were demonstrated between the hardware and smartphone software. Our prototype thus enables convenient SpO<sub>2</sub> measurement over the entire body, while maintaining accuracy comparable to commercial device. Its smartphone application enables accessible and understandable results display to patients, care-givers and healthcare professionals. The application’s display and alert calibration flexibility facilitates the prototype’s usage in changing medical requirements and for various disease and conditions. A device based on this prototype can monitor continuously and accurately patients’ SpO<sub>2</sub> without limiting their everyday activities or disturbing their sleep and can thus significantly im-prove their medical care in both clinics and home.展开更多
Trajectories of pulse oxygen saturation(SpO_(2))within the first few days after birth are important to inform the strategy for identifying asymptomatic hypoxemic disease but remain poorly substantiated at higher altit...Trajectories of pulse oxygen saturation(SpO_(2))within the first few days after birth are important to inform the strategy for identifying asymptomatic hypoxemic disease but remain poorly substantiated at higher altitudes.Methods We performed a longitudinal cohort study with consecutive neonates at a local hospital in Luchun County,China,at an altitude of 1650 m between January and July 2020.We repeatedly measured the pre-and post-ductal SpO_(2)values at 6,12,18,24,36,48,and 72 hours after birth for neonates without oxygen supplements.All neonates underwent echocardiography and were followed up to 42 days after discharge.We included neonates without hypoxemic diseases to characterize the trajectories of SpO_(2)over time using a linear mixed model.We considered the 2.5th percentile as the reference value to define hypoxemic conditions.Results A total of 1061 neonates were enrolled.Twenty-five had non-cardiac hypoxemic diseases,with 84%(21/25)presenting with abnormal SpO_(2)within 24 hours.One had tetralogy of Fallot identified by echocardiography.Among the 1035 asymptomatic neonates,SpO_(2)values declined from 6 hours after birth,reached a nadir at 48 hours,and tended to level off thereafter,with identical patterns for both pre-and post-ductal SpO_(2).The reference percentile was 92%for both pre-and post-ductal SpO_(2)and was time independent.Conclusions A decline within 48 hours features SpO_(2)trajectories within the first 72 hours at moderate altitude.Our findings suggest that earlier screening may favorably achieve a benefit–risk balance in identifying asymptomatic hypoxemic diseases in this population.展开更多
目的:探讨应用脉搏血氧测定法测试牙髓活力的可行性。方法:选用美国产脉搏血氧测定仪(MF5-503)加分离探头,测定110名志愿者的1320颗健康前牙牙髓血氧饱和度(saturation of oxygen,SO2),所得数据进行统计,分析各前牙SO2的相关关系。结果...目的:探讨应用脉搏血氧测定法测试牙髓活力的可行性。方法:选用美国产脉搏血氧测定仪(MF5-503)加分离探头,测定110名志愿者的1320颗健康前牙牙髓血氧饱和度(saturation of oxygen,SO2),所得数据进行统计,分析各前牙SO2的相关关系。结果:全体受试人员上下尖牙、上切牙、下切牙的牙髓SO2平均值分别为0.777±0.006,0.819±0.005,0.858±0.004,经t检验,P<0.05有统计学差异。结论:形态相似的前牙其SO2测定值无显著差异,而形态不同的前牙SO2测定值存在显著差异。脉搏血氧测定仪的探头做一定的改进后用于各牙牙髓活力的判定是可行的。展开更多
文摘BACKGROUND Pulse oximetry has become a cornerstone technology in healthcare,providing non-invasive monitoring of oxygen saturation levels and pulse rate.Despite its widespread use,the technology has inherent limitations and challenges that must be addressed to ensure accurate and reliable patient care.AIM To comprehensively evaluate the advantages,limitations,and challenges of pulse oximetry in clinical practice,as well as to propose recommendations for optimizing its use.METHODS A systematic literature review was conducted to identify studies related to pulse oximetry and its applications in various clinical settings.Relevant articles were selected based on predefined inclusion and exclusion criteria,and data were synthesized to provide a comprehensive overview of the topic.RESULTS Pulse oximetry offers numerous advantages,including non-invasiveness,real-time feedback,portability,and costeffectiveness.However,several limitations and challenges were identified,including motion artifacts,poor peripheral perfusion,ambient light interference,and patient-specific factors such as skin pigmentation and hemoglobin variants.Recommendations for optimizing pulse oximetry use include technological advancements,education and training initiatives,quality assurance protocols,and interdisciplinary collaboration.CONCLUSION Pulse oximetry is crucial in modern healthcare,offering invaluable insights into patients’oxygenation status.Despite its limitations,pulse oximetry remains an indispensable tool for monitoring patients in diverse clinical settings.By implementing the recommendations outlined in this review,healthcare providers can enhance the effectiveness,accessibility,and safety of pulse oximetry monitoring,ultimately improving patient outcomes and quality of care.
文摘Peripheral oxygenation level (SpO<sub>2</sub>) can provide vital information on body functions. Continuous monitoring facilitates effective diagnosis and treatment and can even be lifesaving. Clinical device monitor SpO<sub>2</sub> using a clip, and measure light transmission through the tissue. This method limits the body locations of the clip’s placement and is sensitive to body movement, which hampers continuous SpO<sub>2</sub> monitoring during wakefulness or sleep, thus decreasing its usability in clinics and its accessibility in homecare usage. We developed a portable, wireless, flat and low cost prototype for continuous monitoring of SpO<sub>2</sub> that overcomes those limitations. The prototype enables convenient measurement in larger variety of body locations by spectrophotometric measurements of changes in the optical reflectance unlike other device that measure absorption through the tissue. The original design and signal processing enable reliable signal acquisition, synchronization and control. An Android’s application was developed to provide a user friendly interface for results display on smartphones. The prototype’s measurements were compared to commercial device that simultaneously measured heart rate frequency, transcutaneous oxygen tension (tcPO<sub>2</sub>) and SpO<sub>2</sub>. The prototype’s measurements accurately reflected changes caused by blood pulses, were correlated to the heart rate, and were sensitive to changes in oxygen saturation. Excellent real time behavior and synchronization were demonstrated between the hardware and smartphone software. Our prototype thus enables convenient SpO<sub>2</sub> measurement over the entire body, while maintaining accuracy comparable to commercial device. Its smartphone application enables accessible and understandable results display to patients, care-givers and healthcare professionals. The application’s display and alert calibration flexibility facilitates the prototype’s usage in changing medical requirements and for various disease and conditions. A device based on this prototype can monitor continuously and accurately patients’ SpO<sub>2</sub> without limiting their everyday activities or disturbing their sleep and can thus significantly im-prove their medical care in both clinics and home.
基金supported by the National Key Research and Development Program of China(2021YFC2701004 and 2016YFC1000506)the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2019-I2M-5-002).
文摘Trajectories of pulse oxygen saturation(SpO_(2))within the first few days after birth are important to inform the strategy for identifying asymptomatic hypoxemic disease but remain poorly substantiated at higher altitudes.Methods We performed a longitudinal cohort study with consecutive neonates at a local hospital in Luchun County,China,at an altitude of 1650 m between January and July 2020.We repeatedly measured the pre-and post-ductal SpO_(2)values at 6,12,18,24,36,48,and 72 hours after birth for neonates without oxygen supplements.All neonates underwent echocardiography and were followed up to 42 days after discharge.We included neonates without hypoxemic diseases to characterize the trajectories of SpO_(2)over time using a linear mixed model.We considered the 2.5th percentile as the reference value to define hypoxemic conditions.Results A total of 1061 neonates were enrolled.Twenty-five had non-cardiac hypoxemic diseases,with 84%(21/25)presenting with abnormal SpO_(2)within 24 hours.One had tetralogy of Fallot identified by echocardiography.Among the 1035 asymptomatic neonates,SpO_(2)values declined from 6 hours after birth,reached a nadir at 48 hours,and tended to level off thereafter,with identical patterns for both pre-and post-ductal SpO_(2).The reference percentile was 92%for both pre-and post-ductal SpO_(2)and was time independent.Conclusions A decline within 48 hours features SpO_(2)trajectories within the first 72 hours at moderate altitude.Our findings suggest that earlier screening may favorably achieve a benefit–risk balance in identifying asymptomatic hypoxemic diseases in this population.
文摘目的:探讨应用脉搏血氧测定法测试牙髓活力的可行性。方法:选用美国产脉搏血氧测定仪(MF5-503)加分离探头,测定110名志愿者的1320颗健康前牙牙髓血氧饱和度(saturation of oxygen,SO2),所得数据进行统计,分析各前牙SO2的相关关系。结果:全体受试人员上下尖牙、上切牙、下切牙的牙髓SO2平均值分别为0.777±0.006,0.819±0.005,0.858±0.004,经t检验,P<0.05有统计学差异。结论:形态相似的前牙其SO2测定值无显著差异,而形态不同的前牙SO2测定值存在显著差异。脉搏血氧测定仪的探头做一定的改进后用于各牙牙髓活力的判定是可行的。
