A frequency servo SoC with output power stabilization loop technology for miniaturized atomic clocks

A frequency servo system-on-chip(FS-SoC)featuring output power stabilization technology is introduced in this study for high-precision and miniaturized cesium(Cs)atomic clocks.The proposed power stabilization loop(PSL)technique,incorporating an off-chip power detector(PD),ensures that the output power of the FS-SoC remains stable,mitigating the impact of power fluctuations on the atomic clock's stability.Additionally,a one-pulse-per-second(1PPS)is employed to syn-chronize the clock with GPS.Fabricated using 65 nm CMOS technology,the measured phase noise of the FS-SoC stands at-69.5 dBc/Hz@100 Hz offset and-83.9 dBc/Hz@1 kHz offset,accompanied by a power dissipation of 19.7 mW.The Cs atomic clock employing the proposed FS-SoC and PSL obtains an Allan deviation of 1.7×10^(-11) with 1-s averaging time.

Diagnosis and treatment of refractory infectious diseases using nanopore sequencing technology:Three case reports

BACKGROUND Infectious diseases are still one of the greatest threats to human health,and the etiology of 20%of cases of clinical fever is unknown;therefore,rapid identification of pathogens is highly important.Traditional culture methods are only able to detect a limited number of pathogens and are time-consuming;serologic detection has window periods,false-positive and false-negative problems;and nucleic acid molecular detection methods can detect several known pathogens only once.Three-generation nanopore sequencing technology provides new options for identifying pathogens.CASE SUMMARY Case 1:The patient was admitted to the hospital with abdominal pain for three days and cessation of defecation for five days,accompanied by cough and sputum.Nanopore sequencing of the drainage fluid revealed the presence of orallike bacteria,leading to a clinical diagnosis of bronchopleural fistula.Cefoperazone sodium sulbactam treatment was effective.Case 2:The patient was admitted to the hospital with fever and headache,and CT revealed lung inflammation.Antibiotic treatment for Streptococcus pneumoniae,identified through nanopore sequencing of cerebrospinal fluid,was effective.Case 3:The patient was admitted to our hospital with intermittent fever and an enlarged neck mass that had persisted for more than six months.Despite antibacterial treatment,her symptoms worsened.The nanopore sequencing results indicate that voriconazole treatment is effective for Aspergillus brookii.The patient was diagnosed with mixed cell type classical Hodgkin's lymphoma with infection.CONCLUSION Three-generation nanopore sequencing technology allows for rapid and accurate detection of pathogens in human infectious diseases.

Science and Technology Commissioners Supporting High-Quality Development Project for Hundreds of Counties, Thousands of Towns, and Myriads of Villages in the Context of Rural Revitalization

This paper discusses the important role of science and technology commissioners in the high-quality development of hundreds of counties,thousands of towns,and myriads of villages in the context of rural revitalization,including building bridges,accelerating the transformation of achievements,promoting the value-added of the whole agricultural industry chain,and promoting the rapid development of rural industrial economy.It also discusses the working achievements of science and technology commissioners,in order to promote further development of rural revitalization in Guangdong Province.

A quantitative study of disruptive technology policy texts:An example of China’s artificial intelligence policy

Purpose:The transformative impact of disruptive technologies on the restructuring of the times has attracted widespread global attention.This study aims to analyze the characteristics and shortcomings of China’s artificial intelligence(AI)disruptive technology policy,and to put forward suggestions for optimizing China’s AI disruptive technology policy.Design/methodology/approach:Develop a three-dimensional analytical framework for“policy tools-policy actors-policy themes”and apply policy tools,social network analysis,and LDA topic model to conduct a comprehensive analysis of the utilization of policy tools,cooperative relationships among policy actors,and the trends in policy theme settings within China’s innovative AI technology policy.Findings:We find that the collaborative relationship among the policy actors of AI disruptive technology in China is insufficiently close.Marginal subjects exhibit low participation in the cooperation network and overly rely on central subjects,forming a“center-periphery”network structure.Policy tool usage is predominantly focused on supply and environmental types,with a severe inadequacy in demand-side policy tool utilization.Policy themes are diverse,encompassing topics such as“Intelligent Services”“Talent Cultivation”“Information Security”and“Technological Innovation”,which will remain focal points.Under the themes of“Intelligent Services”and“Intelligent Governance”,policy tool usage is relatively balanced,with close collaboration among policy entities.However,the theme of“AI Theoretical System”lacks a comprehensive understanding of tool usage and necessitates enhanced cooperation with other policy entities.Research limitations:The data sources and experimental scope are subject to certain limitations,potentially introducing biases and imperfections into the research results,necessitating further validation and refinement.Practical implications:The study introduces a three-dimensional analysis framework for disruptive technology policy texts,which is significant for formulating and enhancing disruptive technology policies.Originality/value:This study utilizes text mining and content analysis techniques to quantitatively analyze disruptive technology policy texts.It systematically evaluates China’s AI policies quantitatively,focusing on policy tools,policy actors,policy themes.The study uncovers the characteristics and deficiencies of current AI policies,offering recommendations for formulating and enhancing disruptive technology policies.

Influence of Quantum Information Technology on International Security

Humanity is currently undergoing the fourth industrial revolution,characterized by advancements in artificial intelligence,clean energy,quantum information technology,virtual reality,and biotechnology.This technological revolution is poised to have a profound impact on the world.Quantum information technology encompasses both quantum computing and the transmission of quantum information.This article aims to integrate quantum information technology with international security concerns,exploring its implications for international security and envisioning its groundbreaking significance.

Application and prospects of spatial information technology in CO_(2)sequestration monitoring

This paper systematically reviews the current applications of various spatial information technologies in CO_(2)sequestration monitoring,analyzes the challenges faced by spatial information technologies in CO_(2)sequestration monitoring,and prospects the development of spatial information technologies in CO_(2)sequestration monitoring.Currently,the spatial information technologies applied in CO_(2)sequestration monitoring mainly include five categories:eddy covariance method,remote sensing technology,geographic information system,Internet of Things technology,and global navigation satellite system.These technologies are involved in three aspects:monitoring data acquisition,positioning and data transmission,and data management and decision support.Challenges faced by the spatial information technologies in CO_(2)sequestration monitoring include:selecting spatial information technologies that match different monitoring purposes,different platforms,and different monitoring sites;establishing effective data storage and computing capabilities to cope with the broad sources and large volumes of monitoring data;and promoting collaborative operations by interacting and validating spatial information technologies with mature monitoring technologies.In the future,it is necessary to establish methods and standards for designing spatial information technology monitoring schemes,develop collaborative application methods for cross-scale monitoring technologies,integrate spatial information technologies with artificial intelligence and high-performance computing technologies,and accelerate the application of spatial information technologies in carbon sequestration projects in China.

A Study on the Path of Promoting External Dissemination of Regional Culture with Translation Technology under the Background of New Quality Productivity

With the introduction of the concept of new quality productivity characterized by high technology,efficiency,and quality,various industries in China have ignited a high spirit of innovation and development.Against this background,this article analyzes the significance and current situation of the external dissemination of regional culture and combines the application of translation technology empowered by new quality productivity to explore a path suitable for the wider,more effective,and higher-quality external dissemination of regional culture.The aim is to provide practical experience for promoting the effective dissemination of regional culture in China to the world and better build a cultural power.

Research on the Impact of China’s Foreign Trade Technology Spillover on Green Total Factor Productivity of Countries Along the“Belt and Road”:Based on the Institutional Quality Threshold Effect

China’s growing trade with countries along the“Belt and Road”Initiative is accompanied by a focus on green development.Based on the panel data from 2007 to 2018,this paper establishes a threshold regression model to empirically analyze the institutional quality threshold effect of China’s foreign trade technology spillover on the GTFP of countries along the“Belt and Road.”The results show that China’s foreign trade technology spillover has a significant institutional quality double threshold effect on the green total factor productivity of the countries along the“Belt and Road.”As the institutional quality of the countries along the“Belt and Road”crosses a specific threshold value,the impact of China’s foreign trade technology spillover on the green total factor productivity of the countries along the“Belt and Road”has a significant positive promoting effect,and corresponding suggestions are put forward.

中国龙头科技企业技术创新能力驱动路径研究——基于fsQCA研究方法

为推动中国科技企业高质量发展,提升科技企业创新能力,对中国龙头科技企业技术创新能力进行深入探究。基于企业内部研发资金投入、研发人员投入和税收优惠、地方补贴及行业技术5个前因条件,阐述其对中国龙头科技企业技术创新能力的影响。采用模糊集定性比较分析法对26家中国不同行业上市龙头科技企业进行分析,构建前因条件对创新能力的影响框架,结果发现:从整体看,企业研发投入、地方政府补贴以及行业技术通过不同条件组态影响龙头科技企业创新能力;从企业资源看,相较于研发资金,研发人员对龙头科技企业创新能力的影响更加显著;从外部环境看,市场和政府采用优势互补方式驱动龙头科技企业创新,且市场行业技术对企业创新的影响更显著,地方政府补贴对企业创新发挥显著激励作用。

哪些因素决定了科技龙头企业竞争力?——基于fs QCA的组态效应研究

竞争力是事关科技龙头企业生存和发展的关键问题。当前经济新的下行压力进一步增大,哪些因素决定了科技龙头企业竞争力,这是在理论和实践的双重探索中形成的一个重要时代课题。因为科技龙头企业竞争力影响因素以及因素之间关系十分复杂,所以组态视角和模糊集定性比较分析可作为相对合适的研究方法,深入分析科技龙头企业竞争力的决定因素。单个要素并不构成科技龙头企业竞争力产生的必要条件,科技龙头企业可从3种路径获得较强竞争力,具有适当规模在提升竞争力方面发挥着重要作用。科技龙头企业可以根据实际情况,充分发挥自身有利条件,通过不同的方式实现企业竞争力提升。引入组态视角探究哪些因素决定了科技龙头企业竞争力,有助于深化对科技龙头企业竞争力背后多重因素间复杂互动本质的理性认识,对科技龙头企业提升竞争力具有重要的理论价值与实践意义。

基于RNA-Seq技术的山羊嘴唇黏膜色素沉积相关差异表达基因筛选及初步分析

【目的】通过RNA-Seq技术筛选不同颜色山羊嘴唇色素代谢相关的候选基因,初步揭示山羊嘴唇黏膜颜色差异形成的分子机理,为动物黏膜色素代谢研究提供理论依据。【方法】以嘴唇等面部可视黏膜颜色存在差异的酉州乌羊(乌黑色)和板角山羊(粉色)为研究对象,采用Illumina Hiseq 2000测序平台对嘴唇黏膜组织进行转录组测序,所得序列经质控、组装后,以|log_(2)(Fold Change)|>1且q value<0.05为标准筛选差异表达基因,并对差异表达基因进行功能注释和富集分析。【结果】利用RNA-Seq技术共筛选出249个基因差异表达,其中与粉色嘴唇黏膜组织相比,乌黑色嘴唇黏膜组织中上调基因有218个,下调基因有31个。23个差异表达基因被划分在9种TFs家族中,其中14个基因属于含有锌指结构域的转录因子家族。GO功能富集分析结果显示,差异表达基因主要参与离子转运相关生物学过程和分子功能。KEGG代谢通路富集结果显示,差异表达基因显著富集于催产素、钙、cGMP-PKG信号通路,以及肥厚性心肌病、心脏肌肉收缩等7个与肌肉组织功能相关的信号通路,其中钙和cGMP-PKG信号通路与色素代谢密切相关;此外,ASIP等12个基因富集到MAPK信号通路、cAMP信号通路、黑色素合成信号通路(Melanogenesis)等色素代谢核心通路中;CALML6、OXTR、ATP1A2、ATP1B44个差异表达基因同时富集到多条与色素代谢相关的通路。qRT-PCR结果与测序结果一致,表明测序结果可靠。【结论】初步确定ASIP基因为山羊嘴唇色素代谢的候选基因,CALML6、OXTR、ATP1A2、ATP1B44个基因参与了山羊嘴唇黏膜色素沉积过程,为研究山羊黏膜色素代谢的分子机制提供理论基础,也为探究人类黏膜异常着色的分子机制提供参考。

广东省科技成果转化效率测量与时空特征——基于DEA-Malmquist指数模型

为有效识别广东省科技成果转化的效率与时空特征,促进科技成果更好赋能经济社会高质量发展,运用DEA-Malmquist模型,测算广东省21个地级市在2010—2019年的科技成果转化效率。研究发现,2010年与2019年,全省整体科技成果转化综合效率未达到DEA有效,且2019年的综合效率更低;同时,全要素生产率指数普遍波动较大,各市历年全要素生产率指数差异普遍显著,其中技术进步是影响全要素生产率指数的主要指标。基于此,研究提出平衡研发与转化、推动“政产学研金用服”协同、实施差异化的成果转化战略和加强区域交流合作的政策建议。

Development and technology status of energy storage in depleted gas reservoirs

Utilizing energy storage in depleted oil and gas reservoirs can improve productivity while reducing power costs and is one of the best ways to achieve synergistic development of"Carbon Peak–Carbon Neutral"and"Underground Resource Utiliza-tion".Starting from the development of Compressed Air Energy Storage(CAES)technology,the site selection of CAES in depleted gas and oil reservoirs,the evolution mechanism of reservoir dynamic sealing,and the high-flow CAES and injection technology are summarized.It focuses on analyzing the characteristics,key equipment,reservoir construction,application scenarios and cost analysis of CAES projects,and sorting out the technical key points and existing difficulties.The devel-opment trend of CAES technology is proposed,and the future development path is scrutinized to provide reference for the research of CAES projects in depleted oil and gas reservoirs.

基于DEA-Malmquist模型的广东人工智能领军企业技术创新效率研究

基于DEA(数据包络分析)-Malmquist模型,选取广东人工智能(AI)产业的31家领军企业,对其技术创新效率进行实证分析。对于企业的技术创新效率,用Malmquist技术生产率指标来表示。Malmquist技术生产率指标是技术效率和技术进步的乘积,技术效率则又是规模效率和纯技术效率的乘积。然后再根据静态和动态两个方面的实证分析结果,提出广东人工智能产业未来发展的若干建议。

多因素联动对企业商业模式创新的影响——基于fsQCA方法

运用模糊集定性比较分析(fsQCA)方法,剖析组织惯例(利用式惯例与探索式惯例)、资源重构(资源重组与资源重置)、创新柔性和技术动荡性多因素联动对企业商业模式创新的影响。结果表明,单个因素均不是高/非高商业模式创新产生的必要条件;高商业模式创新产生的组态有3个,即惯例+资源保障的自我适应型、惯例弥补资源的内外协同驱动型和惯例+资源稳定的内外协同驱动型;非高商业模式创新产生的组态有3个,且与高商业模式创新产生的组态呈现非对称性关系。此外,创新柔性在高/非高商业模式创新产生过程中的作用突出,高利用式惯例是高商业模式创新产生的重要条件,非高资源重置是非高商业模式创新产生的重要条件。

“技术-组织-环境”因素联动对企业数字创新的影响——基于新一代信息技术企业的QCA分析

基于“技术-组织-环境”(TOE)框架,使用沪深A股新一代信息技术产业上市企业数据,通过模糊集定性比较分析(fsQCA)方法探寻技术、组织与环境3个层面7个前因条件对企业数字创新的影响。研究发现。(1)企业通过多因素联动实现数字创新,存在4类能够产生高水平数字创新的组态,即技术环境联动的学习转化型、技术环境联动的捕获突破型、技术环境联动的协调开拓型和技术支持的自驱求变型;(2)企业吸收能力在实现高水平数字创新中发挥着重要作用,感知能力则在一定程度上可以替代外部环境对于企业的正向影响作用,环境要素中对数字创新起主要推动作用的是市场竞争程度;(3)缺失数字基础设施、高层次人才、感知能力、吸收能力这4个因素对非高水平数字创新的形成有着相对普遍的作用。因此政府应进一步优化市场竞争与政府支持的动态协同机制,构建企业良好的数字创新环境;新一代信息技术企业则应遵循系统性原则,结合自身优势和外部环境选择提升数字创新绩效的模式,并要积极培育支撑组织数字创新的动态能力,以提升企业创新效率和创新质量。

中国省域科技成果转化效率评价及影响因素分析——基于超效率SBM-Malmquist-Tobit模型

[研究目的]提升省域科技成果转化效率,对提高国家科技发展水平和竞争力具有重要意义。[研究方法]以我国31个省(区、市)为研究对象,运用SBM-Malmquist模型对省域科技成果转化效率进行静态与动态分析,进一步结合Tobit回归模型分析科技成果转化效率的影响因素。[研究结论]我国省域科技成果转化效率整体表现良好,区域间呈现出“中部>东部>西部>东北部”的态势,且各区域之间差异较大。我国科技成果转化效率增长主要得益于技术进步,技术进步对科技成果转化效率的拉动作用抵消了技术效率变化和规模效率变化衰退的影响,市场需求和地区产业结构对科技成果转化效率具有显著正向作用,经济发展水平和财政支持对科技成果转化效率的影响不显著。推进我国科技成果转化效率的提高,仍需要从区域协同、投入产出结构优化、技术进步等方面发力。

Development status and prospect of underground thermal energy storage technology

Underground Thermal Energy Storage(UTES)store unstable and non-continuous energy underground,releasing stable heat energy on demand.This effectively improve energy utilization and optimize energy allocation.As UTES technology advances,accommodating greater depth,higher temperature and multi-energy complementarity,new research challenges emerge.This paper comprehensively provides a systematic summary of the current research status of UTES.It categorized different types of UTES systems,analyzes the applicability of key technologies of UTES,and evaluate their economic and environmental benefits.Moreover,this paper identifies existing issues with UTES,such as injection blockage,wellbore scaling and corrosion,seepage and heat transfer in cracks,etc.It suggests deepening the research on blockage formation mechanism and plugging prevention technology,improving the study of anticorrosive materials and water treatment technology,and enhancing the investigation of reservoir fracture network characterization technology and seepage heat transfer.These recommendations serve as valuable references for promoting the high-quality development of UTES.

6G New Multiple Access Technology

As a basic technology at physical layer of mobile communications,non-orthogonal multiple access has been attracting wide attention across the academia and the industry.During the standardization of the fifth-generation(5G)of mobile communications,3GPP conducted preliminary study on non-orthogonal multiple access without reaching the consensus to standardize the technology.

The Philosophy of He(和):Examined from the Perspectives of Technology and Culture

Pre-modern Chinese crafts,such as iron smelting,cookery,medicine,and the production of vehicles,bows,and arrows indicate the traditional Chinese view of technology as being organic,holistic,and comprehensive.This view of technology is guided by the concept of he(和)and employs the means and methods of he,thus achieving the purport of he.In Chinese,the character he(和)possesses positive connotations.It originated from the meaning of"to season;to add flavoring to"(调和)and that of flavors being"perfectly harmonious"(和美).From this sensory experience,he gradually extended to the abstract levels of materiality,humanity,sociality,"order"(wei位),and "power,situation,force"(shi势).Finally,he was elevated to the supreme level of"qi of great harmony"(taihe zhi qi太和之气),which is comparable to the concept of dao(道).The philosophy of he has exerted wide impact on such areas as technology,art,national character,cultural psychology,and behavior patterns,and has become an integral part of China's inherent culture.The paradoxes and deviations of he hold their own profound philosophical implications that merit further exploration.As humanity confronts significant challenges,such as how we can coexist with others,with technology,and with nature,the ancient Eastern wisdom embodied in he continues to possess practical characteristics and value.