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Thoughts on Pairing Assistance to Tibet for Promoting Agricultural High-quality Development in Southern Tibet from the Perspective of Agricultural Power
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作者 Zhiguo SUN Li GAO +3 位作者 Yuanpeng SUN Guangchao CAO Xinying ZHOU Xiaoqiang LI 《Asian Agricultural Research》 2024年第3期18-24,共7页
In the new era,there is an urgent need to further promote pairing assistance to Tibet,promote the simultaneous construction of a strong agriculture in Tibet and the China's Mainland,and compose a Chinese-style mod... In the new era,there is an urgent need to further promote pairing assistance to Tibet,promote the simultaneous construction of a strong agriculture in Tibet and the China's Mainland,and compose a Chinese-style modernization.Southern Tibet,located in the southeastern part of the Tibet Autonomous Region,includes Shannan City and Nyingchi City,is a region assisted by four provincial partners including Hubei Province.This paper introduces the agricultural environment in southern Tibet,studies its agricultural characteristics,and analyzes the main issues of its pairing assistance.Taking forging the strong consciousness of the Chinese national community as the main line,the paper explores strategies for promoting agricultural high-quality development in southern Tibet through pairing assistance to Tibet from the perspective of agricultural power,and proposes some strategies,such as inheriting agricultural cultural heritage,promoting the upgrading of modern seed industry,enhancing the characteristic advantages of highland barley(naked barley)and animal husbandry industries,and developing edible fungi and cold water fish industries. 展开更多
关键词 pairing aSSISTaNCE to TIBET Southern TIBET Shannan CITY Nyingchi CITY aGRICULTURaL high-quality development aGRICULTURaL power
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Network pharmacology and subsequent experimental validation reveal the synergistic myocardial protection mechanism of Salvia miltiorrhiza Bge.and Carthamus tinctorius L. 被引量:1
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作者 Linying Zhong Ling Dong +7 位作者 Jing Sun Jie Yang Zhiying Yu Ping He Bo Zhu Yuxin Zhu Siyuan Li Wenjuan Xu 《Journal of Traditional Chinese Medical Sciences》 CAS 2024年第1期44-54,共11页
Objective:To reveal the molecular mechanism underlying the compatibility of Salvia miltiorrhiza Bge(S.miltiorrhiza,Dan Shen)and C.tinctorius L.(C.tinctorius,Hong Hua)as an herb pair through network pharmacology and su... Objective:To reveal the molecular mechanism underlying the compatibility of Salvia miltiorrhiza Bge(S.miltiorrhiza,Dan Shen)and C.tinctorius L.(C.tinctorius,Hong Hua)as an herb pair through network pharmacology and subsequent experimental validation.Methods:Network pharmacology was applied to construct an active ingredient-efficacy target-disease protein network to reveal the unique regulation pattern of s.miltiorrhiza and C.tinctorius as herb pair.Molecular docking was used to verify the binding of the components of these herbs and their potential targets.An H9c2 glucose hypoxia model was used to evaluate the efficacy of the components and their synergistic effects,which were evaluated using the combination index.Western blot was performed to detect the protein expression of these targets.Results:Network pharmacology analysis revealed 5 pathways and 8 core targets of s.miltiorrhiza and C.tinctorius in myocardial protection.Five of the core targets were enriched in the hypoxia-inducible factor-1(HIF-1)signaling pathway.S.miltiorrhiza-C.tinctorius achieved vascular tone mainly by regulating the target genes of the HIF-1 pathway.As an upstream gene of the HIF-1 pathway,STAT3 can be activated by the active ingredients cryptotanshinone(Ctan),salvianolic acid B(Sal.B),and myricetin(Myric).Cell experiments revealed that Myric,Sal.B,and Ctan also exhibited synergistic myocardial protective activity.Molecular docking verified the strong binding of Myric,Sal.B,and Ctan to STAT3.Western blot further showed that the active ingredients synergistically upregulated the protein expressionof STAT3.Conclusion:The pharmacodynamic transmission analysis revealed that the active ingredients of S.miltiorrhiza and C.tinctorius can synergistically resist ischemia through various targets and pathways.This study provides a methodological reference for interpreting traditional Chinese medicine compatibility. 展开更多
关键词 S.miltiorrhiza-C.tinctorius herb pair Compatibilitymechanism Networkpharmacology Multipletargeteffect Myocardial protection
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Pairing correlation of the kagome-lattice Hubbard model with the nearest-neighbor interaction
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作者 Chen Yang Chao Chen +2 位作者 Runyu Ma Ying Liang Tianxing Ma 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第10期41-45,共5页
A recently discovered family of kagome lattice materials,AV_(3)Sb_(5)(A=K,Rb,Cs),has attracted great interest,especiallyin the debate over their dominant superconducting pairing symmetry.To explore this issue,we study... A recently discovered family of kagome lattice materials,AV_(3)Sb_(5)(A=K,Rb,Cs),has attracted great interest,especiallyin the debate over their dominant superconducting pairing symmetry.To explore this issue,we study the superconductingpairing behavior within the kagome-lattice Hubbard model through the constrained path Monte Carlo method.It isfound that doping around the Dirac point generates a dominant next-nearest-neighbor-d pairing symmetry driven by on-siteCoulomb interaction U.However,when considering the nearest-neighbor interaction V,it may induce nearest-neighbor-ppairing to become the preferred pairing symmetry.Our results provide useful information to identify the dominant superconductingpairing symmetry in the AV_(3)Sb_(5)family. 展开更多
关键词 kagome-lattice Hubbard model SUPERCONDUCTIVITY pairing symmetry CPMC
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Effects of carrier density and interactions on pairing symmetry in a t_(2g) model
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作者 李云霄 西文翰 +3 位作者 董召阳 姚子健 于顺利 李建新 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期223-230,共8页
By utilizing the fluctuation exchange approximation method,we perform a study on the superconducting pairing symmetry in a t_(2g) three-orbital model on the square lattice.Although the tight-binding parameters of the ... By utilizing the fluctuation exchange approximation method,we perform a study on the superconducting pairing symmetry in a t_(2g) three-orbital model on the square lattice.Although the tight-binding parameters of the model are based on Sr_(2)RuO_(4),we have systematically studied the evolution of superconducting pairing symmetry with the carrier density and interactions,making our findings relevant to a broader range of material systems.Under a moderate Hund’s coupling,we find that spin fluctuations dominate the superconducting pairing,leading to a prevalent spin-singlet pairing with a d_(x^(2)-y^(2))-wave symmetry for the carrier density within the range of n=1.5-4 per site.By reducing the Hund’s coupling,the charge fluctuations are enhanced and play a crucial role in determining the pairing symmetry,leading to a transition of the pairing symmetry from the spin-singlet d_(x^(2)-y^(2))-wave to the spin-triplet p-wave.Furthermore,we find that the superconducting pairings are orbital dependent.As the carrier density changes from n=4 to n=1.5,the active orbitals for superconducting pairing shift from the quasi-two-dimensional orbital dxy to the quasi-one-dimensional orbitals d_(xz) and d_(yz). 展开更多
关键词 unconventional superconductivity pairing mechanism Fermi surface three-orbital model
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Spin-polarized pairing induced by the magnetic field in the Bernal bilayer graphene
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作者 黄妍 周涛 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期650-654,共5页
Recent experimental findings have demonstrated the occurrence of superconductivity in Bernal bilayer graphene when induced by a magnetic field.In this study,we conduct a theoretical investigation of the potential pair... Recent experimental findings have demonstrated the occurrence of superconductivity in Bernal bilayer graphene when induced by a magnetic field.In this study,we conduct a theoretical investigation of the potential pairing symmetry within this superconducting system.By developing a theoretical model,we primarily calculate the free energy of the system with p+ip-wave parallel spin pairing,p+ip-wave anti-parallel spin pairing and d+i d-wave pairing symmetry.Our results confirm that the magnetic field is indeed essential for generating the superconductivity.We discover that the p+ip-wave parallel spin pairing leads to a lower free energy for the system.The numerical calculations of the energy band structure,zero-energy spectral function and density of states for each of the three pairing symmetries under consideration show a strong consistency with the free energy results. 展开更多
关键词 SUPERCONDUCTIVITY magnetic field induction pairing symmetry Bernal bilayer graphene
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Sensitivity impacts owing to the variations in the type of zero-range pairing forces on the fission properties using the density functional theory
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作者 Yang Su Ze-Yu Li +3 位作者 Li-Le Liu Guo-Xiang Dong Xiao-Bao Wang Yong-Jing Chen 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第3期198-207,共10页
Using the Skyrme density functional theory,potential energy surfaces of^(240)Pu with constraints on the axial quadrupole and octupole deformations(q_(20)and q_(30))were calculated.The volume-like and surface-like pair... Using the Skyrme density functional theory,potential energy surfaces of^(240)Pu with constraints on the axial quadrupole and octupole deformations(q_(20)and q_(30))were calculated.The volume-like and surface-like pairing forces,as well as a combination of these two forces,were used for the Hartree–Fock–Bogoliubov approximation.Variations in the least-energy fission path,fission barrier,pairing energy,total kinetic energy,scission line,and mass distribution of the fission fragments based on the different forms of the pairing forces were analyzed and discussed.The fission dynamics were studied based on the timedependent generator coordinate method plus the Gaussian overlap approximation.The results demonstrated a sensitivity of the mass and charge distributions of the fission fragments on the form of the pairing force.Based on the investigation of the neutron-induced fission of^(239)Pu,among the volume,mixed,and surface pairing forces,the mixed pairing force presented a good reproduction of the experimental data. 展开更多
关键词 Nuclear fission Density functional theory pairing force Potential energy surfaces Fission fragment distribution
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基于UPLC-Q-Orbitrap-HRMS技术的葛根-丹参药对化学成分分析
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作者 卢洋 邓小惠 +5 位作者 吴梦瑶 陈萱 陈祥雯 杨宇辉 曹纪亮 万丽 《中南药学》 CAS 2024年第9期2380-2386,共7页
目的采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UPLC-Q-Orbitrap-HRMS)技术分别对以水和50%甲醇溶液为溶剂提取的葛根-丹参药对样品进行化学成分分析。方法采用Thermo Scientific Hypersil GOLD C_(18)色谱柱(150 mm×2.1 ... 目的采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UPLC-Q-Orbitrap-HRMS)技术分别对以水和50%甲醇溶液为溶剂提取的葛根-丹参药对样品进行化学成分分析。方法采用Thermo Scientific Hypersil GOLD C_(18)色谱柱(150 mm×2.1 mm,1.9μm),以0.1%甲酸水-0.1%甲酸乙腈溶液为流动相进行梯度洗脱,流速为0.3 mL·min^(-1),柱温为30℃。采用加热电喷雾离子源(H-ESI),正负离子检测模式。结果从水提和50%甲醇醇提样品溶液中均鉴定出104个化合物,其中103个化合物为共有成分,各有1个差异性成分,分别为水提样品中的刺槐苷与50%甲醇醇提样品中的降丹参酮(或其同分异构体)。共鉴定出的105个化合物,包括黄酮类成分36个、苯丙素类成分20个、萜类成分24个和其他类成分25个。结论本研究首次采用UPLC-Q-Orbitrap-HRMS技术对葛根-丹参药对的主要成分进行鉴定,可为葛根-丹参药对的药效成分研究提供科学依据。 展开更多
关键词 葛根-丹参药对 UPLC-q-Orbitrap-HRMS 化学成分
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Highlighting relationships between sand thicknesses,reservoir-seal pairs and paleobathymetry from a sequence stratigraphic perspective:An example from Tortonian Serravallian deposits,onshore Niger Delta Basin
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作者 Ifeanyichukwu S.Obi K.Mosto Onuoha Chidozie I.Princeton Dim 《Energy Geoscience》 EI 2024年第1期12-23,共12页
The utilization of sequence stratigraphic concepts in identifying sands and their spatial continuity in distinct gross depositional settings is key,especially in frontier settings where data paucity is a common challe... The utilization of sequence stratigraphic concepts in identifying sands and their spatial continuity in distinct gross depositional settings is key,especially in frontier settings where data paucity is a common challenge.In the Baka field,onshore Niger Delta,detailed reservoir correlation guided by sequence stratigraphic framework analysis showed the distribution of sand and shale units constituting reservoirseal pairs(RSP)correlatable across the field.Within the 3rd-order packages,it is observed that the lowstand systems tract(LST)and highstand systems tract(HST)contain more RSPs and thicker 4th-and 5th-order sands than the transgressive systems tract(TST).In terms of bathymetry,it is noted that irrespective of systems tracts,the RSP Index(RI)decreases from the proximal shallow/inner shelf settings to the more distal outer shelf areas.Amongst all three systems tracts,intervals interpreted as lowstand prograding complexes contain the best developed sands and highest RSP.Sand development within the LSTs has been controlled by a pronounced growth fault regime accompanied by high subsidence and sedimentation rates.This is linked to the basinward migration of the sands during prolonged sea-level fall,creating significant accommodation space for sand deposition.On the other hand,the TSTs known to mark periods of progressive sea-level rise and landward migration of sandy facies,show thinner sands enclosed in much thicker,laterally extensive,and better-preserved deeper marine shales.Interpreted seismic sections indicate intense growth faulting and channelization that influenced the syn-and postdepositional development of the sand packages across the field.The initial timing of deformation of subregional faults in this area coincides with periods of abrupt falls in sea level.This approach could be useful for predicting sand-prone areas in frontier fields as well as possible reservoir-seal parameters required for some aspects of petroleum system analysis and quick-look volume estimation. 展开更多
关键词 Reservoir-seal pairs(RSP) Systems tract Coastal swamp depobelt Bathymetry Sequence stratigraphy Niger Delta Basin
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Effect of the mixing of s-wave and chiral p-wave pairings on electrical shot noise properties of normal metal/superconductor tunnel junctions
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作者 胡雨辰 胡梁宾 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期538-545,共8页
We study theoretically the electrical shot noise properties of tunnel junctions between a normal metal and a superconductor with the mixture of singlet s-wave and chiral triplet p-wave pairing due to broken inversion ... We study theoretically the electrical shot noise properties of tunnel junctions between a normal metal and a superconductor with the mixture of singlet s-wave and chiral triplet p-wave pairing due to broken inversion symmetry. We investigate how the shot noise properties vary as the relative amplitude between the two parity components in the pairing potential is changed. It is demonstrated that some characteristics of the electrical shot noise properties of such tunnel junctions may depend sensitively on the relative amplitude between the two parity components in the pairing potential, and some significant changes may occur in the electrical shot noise properties when the relative amplitude between the two parity components is varied from the singlet s-wave pairing dominated regime to the chiral triplet p-wave pairing dominated regime. In the chiral triplet p-wave pairing dominated regime, the ratio of noise power to electric current is close to 2e both in the in-gap and in the out-gap region. In the singlet s-wave pairing dominated regime, the value of this ratio is close to 4e in the inner gap region but may reduce to about 2e in the outer gap region as the relative amplitude of the chiral triplet pairing component is increased. The variations of the differential shot noise with the bias voltage also exhibit some significantly different features in different regimes. Such different features can serve as useful diagnostic tools for the determination of the relative magnitude of the two parity components in the pairing potential. 展开更多
关键词 normal metal/superconductor tunnel junctions shot noise mixing of s-wave and chiral p-wave pairing spin–orbit coupling
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Characterization of meiotic chromosome behavior in the autopolyploid Saccharum spontaneum reveals preferential chromosome pairing without distinct DNA sequence variation
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作者 Xin Zhang Zhuang Meng +4 位作者 Jinlei Han Haris Khurshid Ayman Esh Robert Hasterok Kai Wang 《The Crop Journal》 SCIE CSCD 2023年第5期1550-1558,共9页
Autopolyploidy and allopolyploidy may represent an evolutionary advantage and are more common in plants than assumed. However, less attention has been paid to autopolyploidy than to allopolyploidy,and its evolutionary... Autopolyploidy and allopolyploidy may represent an evolutionary advantage and are more common in plants than assumed. However, less attention has been paid to autopolyploidy than to allopolyploidy,and its evolutionary consequences are largely unclear, especially for plants with high ploidy levels. In this study, we developed oligonucleotide(oligo)-based chromosome painting probes to identify individual chromosomes in S. spontaneum. Using fluorescence in situ hybridization(FISH), we investigated chromosome behavior during pachytene, metaphase, anaphase, and telophase of meiosis I(MI) in autotetraploid,autooctoploid, and autodecaploid S. spontaneum clones. All autopolyploid clones showed stable diploidized chromosome behavior;so that homologous chromosomes formed almost exclusively bivalents during MI. Two copies of homologous chromosome 8 with similar sizes in the autotetraploid clone showed preferential pairing with each other with respect to the other copies. However, sequence variation analysis showed no apparent differences among homologs of chromosome 8 and all other chromosomes. We suggest that either the stable diploidized pairing or the preferential pairing between homologous copies of chromosome 8 in the studied autopolyploid sugarcane are accounted for by unknown mechanisms other than DNA sequence similarity. Our results reveal evolutionary consequences of stable meiotic behavior in autopolyploid plants. 展开更多
关键词 aUTOPOLYPLOIDY Saccharum spontaneum Meiosis I Chromosome behavior Chromosome pairing
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基于Abaqus的汽车制动摩擦副材料特性对界面接触影响分析
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作者 孙应秋 晏成 +1 位作者 林承雄 王晓翠 《兰州工业学院学报》 2024年第3期80-84,共5页
借助Abaqus有限元仿真软件进行了关于摩擦副材料特性对表面接触状态影响的分析。通过构建基于温度变化的灰铸铁制动盘与半金属摩擦片的接触模型,对摩擦界面的热力耦合进行了分析。结果表明:制动盘与摩擦片的高温分布呈现相似性,均为内... 借助Abaqus有限元仿真软件进行了关于摩擦副材料特性对表面接触状态影响的分析。通过构建基于温度变化的灰铸铁制动盘与半金属摩擦片的接触模型,对摩擦界面的热力耦合进行了分析。结果表明:制动盘与摩擦片的高温分布呈现相似性,均为内侧温度整体高于外侧温度,制动盘的温度先上升后下降,摩擦片达到最高值后保持平台分布,制动盘的外侧均呈现最高的位移分布与应力分布。实验结果为未来汽车制动系统的材料设计提供理论依据。 展开更多
关键词 aBaqUS 制动系统 摩擦副 材料特性
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益智仁-乌药药对调控PI3K/Akt/mTOR通路介导细胞自噬保护肾小球足细胞的作用机制研究 被引量:4
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作者 尹德辉 唐诗韵 +2 位作者 吴珠 陈应奇 朱叶 《中华中医药学刊》 CAS 北大核心 2024年第1期30-34,I0004-I0006,共8页
目的研究益智仁-乌药药对通过调控PI3K/Akt/mTOR信号通路促进足细胞自噬治疗糖尿病肾病(Diabetic Nephropathy,DN)的作用。方法60只造模成功的C57BL/KSJ-db/db(以下简称db/db)小鼠随机分为模型组、二甲双胍组、缬沙坦组、益智仁-乌药药... 目的研究益智仁-乌药药对通过调控PI3K/Akt/mTOR信号通路促进足细胞自噬治疗糖尿病肾病(Diabetic Nephropathy,DN)的作用。方法60只造模成功的C57BL/KSJ-db/db(以下简称db/db)小鼠随机分为模型组、二甲双胍组、缬沙坦组、益智仁-乌药药对(低、中、高剂量)组,每组10只;另取10只C57BL/KSJ-db/m(以下简称db/m)小鼠为正常组,正常组和模型组给予生理盐水,治疗组小鼠分别给予相应药物,给药8周后检测小鼠肾脏病理学改变,足细胞自噬体数量、结构及相关蛋白表达。结果与模型组相比,益智仁-乌药药对组可显著减轻糖尿病肾病小鼠肾小球基底膜增厚情况,增加足细胞自噬体数量,显著升高自噬相关蛋白表达(P<0.05),降低PI3K/Akt/mTOR信号通路相关蛋白的表达(P<0.05)。其中益智仁-乌药药对高剂量组各指标改善优于益智仁-乌药低、中剂量组。结论益智仁-乌药药对通过抑制PI3K/Akt/mTOR信号通路激活,提高足细胞自噬水平,减轻足细胞损伤,发挥治疗糖尿病肾病的作用。 展开更多
关键词 益智仁-乌药药对 糖尿病肾病 PI3K/aKT/MTOR 足细胞 自噬
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ABAQUS二次开发在多片式摩擦副仿真中的应用
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作者 王延忠 于祥云 +1 位作者 窦德龙 张震 《计算机仿真》 北大核心 2023年第5期117-122,共6页
针对一种多片式摩擦副结构,基于Python语言对ABAQUS软件的前处理过程进行二次开发,简化多片式摩擦副制动仿真建模过程。通过编写主控程序Frictionmodel.py,图形界面程序FrictionmodelDB.py和关联程序Frictionmodel_plugin.py,实现系统... 针对一种多片式摩擦副结构,基于Python语言对ABAQUS软件的前处理过程进行二次开发,简化多片式摩擦副制动仿真建模过程。通过编写主控程序Frictionmodel.py,图形界面程序FrictionmodelDB.py和关联程序Frictionmodel_plugin.py,实现系统建模程序定制,对不同对数、不同尺寸的多片式摩擦结构进行快速建模,基于三维瞬态热传导理论进行航空用舱门无返回装置紧急制动工况下瞬态热应力场的有限元分析计算。结果表明,随着摩擦副数的增多,制动力增大,制动时间逐渐减少,制动温升也会降低;但接触压力分布情况也会逐渐变差,出现应力集中。通过对比分析,三对副摩擦片结构可以保持高效制动的同时,满足结构尺寸及温度要求。 展开更多
关键词 多片式摩擦副 二次开发 有限元
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基于配对检验的ARIMA模型在我国甲肝发病数预测中的应用
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作者 丁勇 张蓓蓓 吴静 《南京医科大学学报(自然科学版)》 CAS 北大核心 2024年第10期1456-1461,共6页
目的:探讨基于配对检验的求和自回归移动平均(autoregressive integrated moving average,ARIMA)模型在我国甲肝发病预测中的应用,提出时间序列模型预测效果评价的新思路与方法。方法:根据2004年1月—2021年12月我国甲肝传染病月发病数... 目的:探讨基于配对检验的求和自回归移动平均(autoregressive integrated moving average,ARIMA)模型在我国甲肝发病预测中的应用,提出时间序列模型预测效果评价的新思路与方法。方法:根据2004年1月—2021年12月我国甲肝传染病月发病数建立ARIMA模型,对2022年1—8月的甲肝月发病数进行预测,通过配对t检验和误差分析评估该模型的预测效果。结果:配对t检验结果显示,ARIMA(1,1,0)(0,1,1)12模型预测的甲肝月发病数与实际月发病数差异无统计学意义(P>0.05),说明模型有较好的预测能力,预测结果的相对误差平均值为3.86%,标准差为3.25%。结论:ARIMA乘积季节模型能够较准确地预测我国甲肝的发病趋势;配对检验为时间序列模型预测效果的评价提供了客观评价依据,较好地解决了时间序列模型预测效果的评价问题。 展开更多
关键词 配对检验 甲型肝炎 aRIMa乘积季节模型 预测
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乳腺癌患者病理特征与Bcl-2、CXCL13、PAX8表达情况的关系分析 被引量:1
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作者 王洋 刘伟 +2 位作者 韩晓东 马娜 秦蕊 《检验医学与临床》 CAS 2024年第10期1431-1435,共5页
目的分析乳腺癌患者病理特征与B细胞淋巴瘤/白血病-2基因(Bcl-2)、趋化因子配体13(CXCL13)、配对盒基因8抗体(PAX8)表达情况的关系。方法收集2021年1月至2023年1月该院收治的160例乳腺癌患者临床资料。采用免疫组化法对其癌组织与癌旁组... 目的分析乳腺癌患者病理特征与B细胞淋巴瘤/白血病-2基因(Bcl-2)、趋化因子配体13(CXCL13)、配对盒基因8抗体(PAX8)表达情况的关系。方法收集2021年1月至2023年1月该院收治的160例乳腺癌患者临床资料。采用免疫组化法对其癌组织与癌旁组织Bcl-2、CXCL13、PAX8表达情况进行检测,并分析3项指标与患者病理特征的关系。结果与癌旁组织比较,癌组织Bcl-2、CXCL13、PAX8阳性率更高,差异有统计学意义(P<0.05)。与雌激素受体(ER)阴性、肿瘤最大径≥3 cm、孕激素受体(PR)阴性患者比较,ER阳性、肿瘤最大径<3 cm、PR阳性患者中Bcl-2高表达占比更高,差异有统计学意义(P<0.05);与无淋巴结转移、Ⅰ~Ⅱ期患者比较,淋巴结转移、Ⅲ~Ⅳ期患者中CXCL13高表达占比更高,差异有统计学意义(P<0.05);与Ⅰ~Ⅱ期、高/中分化、无淋巴结转移患者比较,Ⅲ~Ⅳ期、低分化、有淋巴结转移患者中PAX8高表达占比更高,差异有统计学意义(P<0.05)。ER、PR表达情况与Bcl-2表达情况呈正相关(P<0.05),肿瘤最大径与Bcl-2表达情况呈负相关(P<0.05);临床分期、淋巴结转移情况与CXCL13、PAX8表达情况呈正相关(P<0.05);分化程度与PAX8表达情况呈负相关(P<0.05)。结论乳腺癌患者Bcl-2、CXCL13、PAX8表达情况对疾病的发生和发展具有明显影响,有望成为评估乳腺癌患者病情严重程度的标志物。 展开更多
关键词 乳腺癌 B细胞淋巴瘤/白血病-2 趋化因子配体13 配对盒基因8抗体 临床病理
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非暴力沟通联合think-pair-share模式培训在普外科护士在职培训中的应用研究
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作者 陈钧 潘红英 +2 位作者 肖悦 王娅娅 姚林燕 《中国高等医学教育》 2024年第7期132-133,136,共3页
目的:探讨非暴力沟通联合think-pair-share(TPS)模式培训在普外科护士在职培训中的应用效果。方法:2020年10月至2021年10月选取本院普外科的4个护理单元,通过随机抽签法分为试验组和对照组,试验组参加非暴力沟通联合TPS模式培训,对照组... 目的:探讨非暴力沟通联合think-pair-share(TPS)模式培训在普外科护士在职培训中的应用效果。方法:2020年10月至2021年10月选取本院普外科的4个护理单元,通过随机抽签法分为试验组和对照组,试验组参加非暴力沟通联合TPS模式培训,对照组参与常规非暴力沟通培训。对比两组护士临床沟通能力、患者满意度以及教学满意度的差异。结果:试验组护士临床沟通能力、患者满意度、教学满意度调查结果均优于对照组(P<0.001)。结论:非暴力沟通联合TPS模式培训在普外科护士在职培训中能提高普外科护士的护患沟通能力,提升其岗位胜任力。 展开更多
关键词 非暴力沟通 think-pair-share 外科 护士 在职培训
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多用户全双工协作PNOMA系统非正交率控制及功率分配优化算法
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作者 申滨 张楠 董坤明 《电子学报》 EI CAS CSCD 北大核心 2024年第6期1842-1851,共10页
传统NOMA系统远近用户设备(User Equipment,UE)之间在时频资源上信号完全重叠,以期获得最高的频率利用率,但其中UE之间的干扰也成为核心问题之一.部分NOMA(Partial NOMA,PNOMA)系统由于仅在部分频段实现NOMA共存,因此可以优化协调UE之... 传统NOMA系统远近用户设备(User Equipment,UE)之间在时频资源上信号完全重叠,以期获得最高的频率利用率,但其中UE之间的干扰也成为核心问题之一.部分NOMA(Partial NOMA,PNOMA)系统由于仅在部分频段实现NOMA共存,因此可以优化协调UE之间的干扰.相较于传统NOMA系统,PNOMA系统能够极大地降低非理想连续干扰相消(imperfect Successive Interference Cancellation,ipSIC)对于系统和速率的消极影响.基于全双工协作NOMA(Full Duplex Cooperative NOMA,FD-CNOMA)系统和PNOMA系统,本文提出了一种全双工协作部分NOMA(FDCPNOMA)方案以优化UE之间干扰,提高系统可达速率.考虑由一个基站和若干个远近UE构成的FD-CPNOMA系统,针对实际中存在非理想连续干扰消除问题,本文给出了UE配对、非正交率控制及功率分配的优化算法,并推导了此模型下UE中断概率闭式解.仿真结果表明,本文提出的UE配对方案性能优于其他三种配对方案,所提出的PNOMA系统最大可达速率均优于相应的传统NOMA系统,提出的FD-CPNOMA系统在低信噪比下的最大可达速率比半双工协作部分NOMA(HD-CPNOMA)系统和PNOMA系统分别高出95.42%、44.06%,并且在高信噪比下可以较好地实现UE间公平性和平均可达速率的折衷. 展开更多
关键词 FD-CPNOMa 非理想连续干扰消除 UE配对 功率分配 中断概率 平均可达速率
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修正Boussinesq方程的N-次Darboux变换与精确解 被引量:1
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作者 乌日乐 套格图桑 扎其劳 《内蒙古师范大学学报(自然科学汉文版)》 CAS 2023年第1期81-86,共6页
基于一个3×3矩阵Lax对,研究修正Boussinesq方程的N-次Darboux变换。首先给出修正Boussinesq方程Darboux变换的简捷证明。其次通过迭代给出N-次Darboux变换,最后利用Darboux变换获得修正Boussinesq方程和Boussinesq方程的精确解。
关键词 BOUSSINESq方程 DaRBOUX变换 3×3矩阵Lax对 精确解
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Pairing effects on the fragment mass distribution of Th,U,Pu,and Cm isotopes 被引量:1
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作者 Xin Guan Jin‑Huan Zheng Mei‑Yan Zheng 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第11期128-139,共12页
In this article,a comprehensive study of the fission process of Th,U,Pu,and Cm isotopes using a Yukawa-folded meanfield plus standard pairing model is presented.The study focused on analyzing the effects of the pairin... In this article,a comprehensive study of the fission process of Th,U,Pu,and Cm isotopes using a Yukawa-folded meanfield plus standard pairing model is presented.The study focused on analyzing the effects of the pairing interaction on the fragment mass distribution and its dependence on nuclear elongation.The significant role of pairing interactions in the fragment mass distributions of^(230)Th,^(234)U,^(240)Pu,and^(246)Cm was demonstrated.Numerical analysis revealed that increasing the pairing interaction strength decreased the asymmetric fragment mass distribution and increased the symmetric distribution.Furthermore,the odd-even mass differences at symmetric and asymmetric fission points were examined,highlighting their sensitivity to changes in the pairing interaction strength.Systematic analysis of the Th,U,Pu,and Cm isotope fragment mass distributions demonstrated the effectiveness of the model in reproducing the experimental data.In addition,the effects of the zero-point energy and half-width parameter on the fragment mass distribution for^(240)Pu were explored.Thus,this study provides valuable insights into the fission process by emphasizing the importance of pairing interactions and their relationship with nuclear elongation. 展开更多
关键词 Nuclear fission pairing interaction Fragment mass distribution actinide nuclei
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Quantum Monte Carlo study of the dominating pairing symmetry in doped honeycomb lattice 被引量:1
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作者 Xingchuan Zhu Tao Ying +1 位作者 Huaiming Guo Shiping Feng 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第7期434-438,共5页
We perform a systematic determinant quantum Monte Carlo(DQMC) study of the dominating pairing symmetry in a doped honeycomb lattice.The Hubbard model is simulated over a full range of filling levels for both weak and ... We perform a systematic determinant quantum Monte Carlo(DQMC) study of the dominating pairing symmetry in a doped honeycomb lattice.The Hubbard model is simulated over a full range of filling levels for both weak and strong interactions.For weak couplings, the d-wave state dominates.The effective susceptibility as a function of filling shows a peak, and its position moves toward half filling as the temperature is increased, from which the optimal filling of the superconducting ground state is estimated.Although the sign problem becomes severe for strong couplings, the simulations access the lowest temperature at which the DQMC method generates reliable results.As the coupling is strengthened, the d-wave state is enhanced in the high-filling region.Our systematic DQMC results provide new insights into the superconducting pairing symmetry in the doped honeycomb lattice. 展开更多
关键词 DETERMINaNT qUaNTUM MONTE Carlo(DqMC) simulation HONEYCOMB lattice SUPERCONDUCTING pairing symmetry
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