目的:探讨水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光对黄褐斑患者疗效及生活质量的影响。方法:选取2018年6月-2019年12月笔者医院收治的黄褐斑女性患者112例,根据患者治疗方案分为研究组55例和对照组57例。对照组采...目的:探讨水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光对黄褐斑患者疗效及生活质量的影响。方法:选取2018年6月-2019年12月笔者医院收治的黄褐斑女性患者112例,根据患者治疗方案分为研究组55例和对照组57例。对照组采用Q开关1064 nm激光治疗,研究组采用水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗,每4周1次,疗程共6个月。比较两组疗效及1年后复发率,比较治疗3、6个月后的黄褐斑生活质量评分量表(Chinesemelasma quality of life scale,Ch-MELASQOL)评分、黄褐斑面积与严重程度指数量表(MASI)评分、满意度评分。结果:治疗6个月后,研究组总有效率为80.00%高于对照组的57.89%。随访1年,研究组无复发,对照组复发率10.53%(6/57)高于研究组(P<0.05)。治疗3、6个月后,研究组的Ch-MELASQOL评分、MASI评分均低于对照组(P<0.05)。研究组治疗后的满意度评分高于对照组(P<0.05)。结论:水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗黄褐斑效果良好,可提高患者生活质量,减少复发。展开更多
An efficient 1064-nm Nd：YVO_4laser in-band pumped by a wavelength-locked laser diode（LD） at 913.9 nm was demonstrated. The maximum continuous wave（CW） output power of 23.4 W at 1064 nm was realized with the incid...An efficient 1064-nm Nd：YVO_4laser in-band pumped by a wavelength-locked laser diode（LD） at 913.9 nm was demonstrated. The maximum continuous wave（CW） output power of 23.4 W at 1064 nm was realized with the incident pump power of 40 W, corresponding to a total optical-to-optical efficiency of 58.5%. This is to the best of our knowledge the highest total optical-to-optical efficiency and output power of Nd：YVO_4laser in-band pumped by a 913.9-nm laser diode.The Q-switched operation of this laser was also investigated. Through a contrast experiment of pumping at 808 nm, the experimental results showed that an Nd：YVO_4laser in-band pumped by a wavelength-locked LD at 913.9 nm had excellent pulse stability and beam quality for high repetition rate Q-switching operation.展开更多
文摘目的:探讨水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光对黄褐斑患者疗效及生活质量的影响。方法:选取2018年6月-2019年12月笔者医院收治的黄褐斑女性患者112例,根据患者治疗方案分为研究组55例和对照组57例。对照组采用Q开关1064 nm激光治疗,研究组采用水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗,每4周1次,疗程共6个月。比较两组疗效及1年后复发率,比较治疗3、6个月后的黄褐斑生活质量评分量表(Chinesemelasma quality of life scale,Ch-MELASQOL)评分、黄褐斑面积与严重程度指数量表(MASI)评分、满意度评分。结果:治疗6个月后,研究组总有效率为80.00%高于对照组的57.89%。随访1年,研究组无复发,对照组复发率10.53%(6/57)高于研究组(P<0.05)。治疗3、6个月后,研究组的Ch-MELASQOL评分、MASI评分均低于对照组(P<0.05)。研究组治疗后的满意度评分高于对照组(P<0.05)。结论:水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗黄褐斑效果良好,可提高患者生活质量,减少复发。
基金Project supported by Tianjin City High School Science&Technology Fund Planning Project(Grant No.20140703)
文摘An efficient 1064-nm Nd：YVO_4laser in-band pumped by a wavelength-locked laser diode（LD） at 913.9 nm was demonstrated. The maximum continuous wave（CW） output power of 23.4 W at 1064 nm was realized with the incident pump power of 40 W, corresponding to a total optical-to-optical efficiency of 58.5%. This is to the best of our knowledge the highest total optical-to-optical efficiency and output power of Nd：YVO_4laser in-band pumped by a 913.9-nm laser diode.The Q-switched operation of this laser was also investigated. Through a contrast experiment of pumping at 808 nm, the experimental results showed that an Nd：YVO_4laser in-band pumped by a wavelength-locked LD at 913.9 nm had excellent pulse stability and beam quality for high repetition rate Q-switching operation.
