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QFT-G试验在结核性胸膜炎诊断的应用探讨
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作者 蒋玲 《中华临床医师杂志(电子版)》 CAS 2016年第7期60-61,共2页
目的 探讨QFT-G 试验在结核性胸膜炎诊断的应用.方法 选取2015-10 至2016-2 月在我院结核科收治的疑似结核性胸膜炎的108 例患者通过QFT-G 试验、PPD 试验、结核抗体检测、结核菌培养等方式进行诊断确认.结果 108 例胸腔积液患者中诊断... 目的 探讨QFT-G 试验在结核性胸膜炎诊断的应用.方法 选取2015-10 至2016-2 月在我院结核科收治的疑似结核性胸膜炎的108 例患者通过QFT-G 试验、PPD 试验、结核抗体检测、结核菌培养等方式进行诊断确认.结果 108 例胸腔积液患者中诊断结核性胸膜炎72 例,非结核性胸膜炎36 例,QFT-G 在72 例结核性胸膜炎患者中检出64 例阳性,检测阳性率高于其它方法,QFT-G 试验诊断真阳性率88.9%,真阴性率91.6%; 假阴性率11.1%,假阳性率8.4%; 阳性似然比7.9,阴性似然比0.12,正确诊断指数达80.6%,QFT-G 试验对结核性胸膜炎诊断的敏感性为88.9%,准确率为89.1%,经比较均高于其它几种诊断方法(P〈0.05)而特异性除PPD 试验外,与其它方法比较均无统计学差异(P〉0.05).结论 QFT-G 试验具有较好的敏感性、特异性、准确性,可以作为一种新的实验方法用于结核性胸腔积液的诊断. 展开更多
关键词 qft-g试验 结核性胸膜炎 PPD试验 结核抗体检测 结核菌培养
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QuantiFERON-TB GOLD对活动性结核病的诊断价值及影响因素分析
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作者 王移欢 段绍琪 +2 位作者 孙杰 陈曦 刘凤君 《医学理论与实践》 2023年第7期1085-1088,1084,共5页
目的:探讨γ干扰素释放实验QuantiFERON-TB GOLD(QFT-G)对活动性结核病的诊断价值及影响因素。方法:回顾性分析2018年7月—2019年7月在川北医学院附属医院行QFT-G检测的住院患者的资料,分析QFT-G在活动性结核病诊断中的敏感性、特异性... 目的:探讨γ干扰素释放实验QuantiFERON-TB GOLD(QFT-G)对活动性结核病的诊断价值及影响因素。方法:回顾性分析2018年7月—2019年7月在川北医学院附属医院行QFT-G检测的住院患者的资料,分析QFT-G在活动性结核病诊断中的敏感性、特异性及影响因素。结果:(1)活动性结核QFT-G的敏感度、特异度、阳性预测值及阴性预测值分别为80.04%、59.30%、71.46%、81.20%。陈旧性结核QFT-G阳性率为66.39%。(2)年龄>61岁(OR=2.463,95%CI=1.026~5.917,P=0.044)、实体肿瘤合并感染(OR=2.813,95%CI=1.144~6.918,P=0.024)和风湿性疾病(OR=6.122,95%CI=2.132~17.576,P=0.001)分别是QFT-G假阴性、假阳性和不确定结果的独立影响因素。结论:(1)QFT-G敏感度较好,但特异性不理想,对于结核的排除价值更高。(2)QFT-G不适合用于鉴别活动性及陈旧性结核。(3)QFT-G用于年龄>61岁、实体肿瘤合并感染、风湿性疾病患者诊断结核时需注意假阴性、假阳性和不确定结果。 展开更多
关键词 结核 γ干扰素释放实验 qft-g 影响因素
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Yang-Mills Mass Gap Problem: A Possible Solution
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作者 Antonio Puccini 《Journal of Applied Mathematics and Physics》 2023年第6期1755-1794,共40页
As known, the spontaneous symmetry breaking (SSB) and the Brout-Englert-Higgs Mechanism (BEH-M) solved the Yang-Mills Mass Gap Problem. However, various mathematicians, even prestigious ones, consider the basic assump... As known, the spontaneous symmetry breaking (SSB) and the Brout-Englert-Higgs Mechanism (BEH-M) solved the Yang-Mills Mass Gap Problem. However, various mathematicians, even prestigious ones, consider the basic assumptions of the gauge theories to be wrong, as well as in conflict with the experimental evidence and in clear disagreement with the facts, distorting the physical reality itself. Likewise, these theories are mathematically inconsistent, adopting a mathematical structure somewhat complicated and arbitrary, which does not satisfy the strong demands for coherence. The weakest point of the gauge theories, in our opinion, consists in imposing that all the particles must be free of an intrinsic mass. On the contrary, even for the particle considered universally massless, i.e. the photon, our calculations show a dynamic-mass, a push-momentum (p) of 1.325 × 10<sup>-22</sup> [g⋅cm/s]. With this work we try to provide a possible solution to the Yang-Mills Mass Gap Problem, but without taking into account the SSB, nor using the BEH-M. We try to provide a mathematical explanation for this phenomenon, considering that in the spectrum of the Yang-Mills theory, there is a mass gap, that is, the difference between the energy of the vacuum state and the first excited state is different from zero. In other words, the lightest of the particles predicted by the theory must have a strictly positive mass to explain the short range of strong nuclear forces. It is clear, indeed, that if we replaced this value with the null value of the photon inserted in the equations of the Perturbation Theory, the Quantum Fields Theory and the Yang-Mills theories, all divergences, that is all zeroes and infinities, would suddenly disappear. Consequently, the limits imposed by the SSB disappear so that there is no longer any need to deny the mass to the Nuclear Forces bosons, including the Yang-Mills b quantum. 展开更多
关键词 Electromagnetic (EM) Quantum Fields Theory (QFT) Spontaneous Symmetry Breaking (SSB) Gluon (G) Photon (P)
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