Objective: To observe the effect and clinical significance of circulating endothelial cells (CEC) in the pathogenesis of coronary heart disease with unstable angina pectoris (CHD-UAP), and to explore the protective ef...Objective: To observe the effect and clinical significance of circulating endothelial cells (CEC) in the pathogenesis of coronary heart disease with unstable angina pectoris (CHD-UAP), and to explore the protective effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi (CH) on CHD-UAP patient's CEC. Methods: Sixty patients with diagnosis of CHD-UAP confirmed and differentiated to be Qi-deficiency and blood stasis by TCM were randomly divided into two groups and treated, on the basis of Western drug-therapy, with Tongxinluo capsule (通心络胶囊, TXL) and Huoxue Tongmai capsule (活血通脉胶囊, HXTM) respectively by way of oral taking three times a day, 3 capsules every time, with 1 month as one therapeutic course. The number of CEC in patients' blood circulation was counted before and after treatment. Besides, the number of CEC in 30 healthy persons was also counted for control. Results: The number of CEC in CHD-UAP patients was significantly higher than that in the healthy persons (P<0.01). After the patients were treated with CH, either TXL or HXTM, it significantly decreased (P<0.01)with insignificant difference between the two treated groups. Conclusion: CEC in CHD-UAP patients is severely damaged and endothelial function in disorder, Chinese herbs have protective effect on patients' CEC.展开更多
盆腔炎性疾病(Pelvic inflammation disease,PID)是妇科临床常见病和多发病,如果治疗不当或病程迁延较久,则会发展成为盆腔炎性疾病后遗症(Sequelae of PID,SPID),盆腔炎性疾病后遗症可致不孕、输卵管妊娠和盆腔充血综合征等,严重影响...盆腔炎性疾病(Pelvic inflammation disease,PID)是妇科临床常见病和多发病,如果治疗不当或病程迁延较久,则会发展成为盆腔炎性疾病后遗症(Sequelae of PID,SPID),盆腔炎性疾病后遗症可致不孕、输卵管妊娠和盆腔充血综合征等,严重影响妇女健康和生活质量。本文对黑龙江中医药大学附属第一医院门诊电子诊疗系统收集的以“活血化瘀法”治疗盆腔炎性疾病后遗症(Sequelae of pelvic inflammatory disease,SPID)的临床中药方剂进行收集整理和数据挖掘,得到核心药物及组方,为临床用药提供指导及参考。展开更多
文摘Objective: To observe the effect and clinical significance of circulating endothelial cells (CEC) in the pathogenesis of coronary heart disease with unstable angina pectoris (CHD-UAP), and to explore the protective effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi (CH) on CHD-UAP patient's CEC. Methods: Sixty patients with diagnosis of CHD-UAP confirmed and differentiated to be Qi-deficiency and blood stasis by TCM were randomly divided into two groups and treated, on the basis of Western drug-therapy, with Tongxinluo capsule (通心络胶囊, TXL) and Huoxue Tongmai capsule (活血通脉胶囊, HXTM) respectively by way of oral taking three times a day, 3 capsules every time, with 1 month as one therapeutic course. The number of CEC in patients' blood circulation was counted before and after treatment. Besides, the number of CEC in 30 healthy persons was also counted for control. Results: The number of CEC in CHD-UAP patients was significantly higher than that in the healthy persons (P<0.01). After the patients were treated with CH, either TXL or HXTM, it significantly decreased (P<0.01)with insignificant difference between the two treated groups. Conclusion: CEC in CHD-UAP patients is severely damaged and endothelial function in disorder, Chinese herbs have protective effect on patients' CEC.
文摘盆腔炎性疾病(Pelvic inflammation disease,PID)是妇科临床常见病和多发病,如果治疗不当或病程迁延较久,则会发展成为盆腔炎性疾病后遗症(Sequelae of PID,SPID),盆腔炎性疾病后遗症可致不孕、输卵管妊娠和盆腔充血综合征等,严重影响妇女健康和生活质量。本文对黑龙江中医药大学附属第一医院门诊电子诊疗系统收集的以“活血化瘀法”治疗盆腔炎性疾病后遗症(Sequelae of pelvic inflammatory disease,SPID)的临床中药方剂进行收集整理和数据挖掘,得到核心药物及组方,为临床用药提供指导及参考。
