Hydrogen sulfide(H_(2)S) not only presents significant environmental concerns but also induces severe corrosion in industrial equipment,even at low concentrations.Among various technologies,the selective oxidation of ...Hydrogen sulfide(H_(2)S) not only presents significant environmental concerns but also induces severe corrosion in industrial equipment,even at low concentrations.Among various technologies,the selective oxidation of hydrogen sulfide(SOH_(2)S) to elemental sulfur(S) has emerged as a sustainable and environmentally friendly solution.Due to its unique properties,iron oxide has been extensively investigated as a catalyst for SOH_(2)S;however,rapid deactivation has remained a significant drawback.The causes of iron oxide-based catalysts deactivation mechanisms in SOH_(2)S,including sulfur or sulfate deposition,the transformation of iron species,sintering and excessive oxygen vacancy formation,and active site loss,are thoroughly examined in this review.By focusing on the deactivation mechanisms,this review aims to provide valuable insights into enhancing the stability and efficiency of iron-based catalysts for SOH_(2)S.展开更多
Understanding the mechanism of oxidative stress is likely to yield new insights regarding the pathogenesis of Alzheimer’s disease (AD). Our earlier work focused on the difference between hemoglobin and methemoglobin ...Understanding the mechanism of oxidative stress is likely to yield new insights regarding the pathogenesis of Alzheimer’s disease (AD). Our earlier work focused on the difference between hemoglobin and methemoglobin degradation, respectively leading to ferrous (Fe2+) iron, or ferric (Fe3+) iron. Methemoglobin has the role of carrier, the donor of cytotoxic and redox-active ferric (Fe3+) iron, which can directly accumulate and increase the rate of capillary endothelial cell apoptosis, and may cross into the brain parenchyma, to the astrocytes, glia, neurons, and other neuronal cells (neurovascular unit). This supposition helps us to understand the transport and neuronal accumulation process of ferric iron, and determine how iron is transported and accumulated intracellularly, identifiable as “Brain rust”. Earlier research found that the incidences of neonatal jaundice (p = 0.034), heart murmur (p = 0.011) and disorders such as dyslalia and learning/memory impairments (p = 0.002) were significantly higher in those children born from mothers with methemoglobinemia. Our hypothesis suggests that prenatal iron abnormalities could lead to greater neuronal death, the disease ageing process, and neurodegenerative disorders such as AD and other neurodegenerative diseases.展开更多
Objective To compare the phase radians in several cerebral regions between patients with Parkinson’s disease （PD） and control subjects, and to evaluate whether iron deposition quantified by susceptibility-weighted ...Objective To compare the phase radians in several cerebral regions between patients with Parkinson’s disease （PD） and control subjects, and to evaluate whether iron deposition quantified by susceptibility-weighted imaging （SWI） is related to the severity of motor symptoms of PD. Methods SWI consisted of both magnitude and phase images from a fully flow-compensated, 3-dimensional and gradient-echo （GRE） sequence. Magnitude and phase data were collected at GE HD 1.5T. The regions evaluated included frontal white matter, grey matter, cerebrospinal fluid, putamen, caudate nucleus （CN）, sub- stantia nigra pars compacta （SNc）, substantia nigra pars reticulata （SNr）, and red nucleus （RN）. A total number of 42 patients （12 patients without cognitive dysfunction, and 30 with cognitive dysfunction from mild to moderate degrees） and 30 control subjects were employed in the present study. Results The phase radians of SNc, CN and RN in PD patients were lower than those in control subjects （P〈0.05）. Conclusion The phase radians can be used to estimate the brain iron deposition in PD patients, which may be helpful in the diagnosis and longitudinal monitoring of PD.展开更多
基金supported by Thailand Science Research and Innovation Fund Chulalongkorn University,Thailand(IND66210014)。
文摘Hydrogen sulfide(H_(2)S) not only presents significant environmental concerns but also induces severe corrosion in industrial equipment,even at low concentrations.Among various technologies,the selective oxidation of hydrogen sulfide(SOH_(2)S) to elemental sulfur(S) has emerged as a sustainable and environmentally friendly solution.Due to its unique properties,iron oxide has been extensively investigated as a catalyst for SOH_(2)S;however,rapid deactivation has remained a significant drawback.The causes of iron oxide-based catalysts deactivation mechanisms in SOH_(2)S,including sulfur or sulfate deposition,the transformation of iron species,sintering and excessive oxygen vacancy formation,and active site loss,are thoroughly examined in this review.By focusing on the deactivation mechanisms,this review aims to provide valuable insights into enhancing the stability and efficiency of iron-based catalysts for SOH_(2)S.
文摘Understanding the mechanism of oxidative stress is likely to yield new insights regarding the pathogenesis of Alzheimer’s disease (AD). Our earlier work focused on the difference between hemoglobin and methemoglobin degradation, respectively leading to ferrous (Fe2+) iron, or ferric (Fe3+) iron. Methemoglobin has the role of carrier, the donor of cytotoxic and redox-active ferric (Fe3+) iron, which can directly accumulate and increase the rate of capillary endothelial cell apoptosis, and may cross into the brain parenchyma, to the astrocytes, glia, neurons, and other neuronal cells (neurovascular unit). This supposition helps us to understand the transport and neuronal accumulation process of ferric iron, and determine how iron is transported and accumulated intracellularly, identifiable as “Brain rust”. Earlier research found that the incidences of neonatal jaundice (p = 0.034), heart murmur (p = 0.011) and disorders such as dyslalia and learning/memory impairments (p = 0.002) were significantly higher in those children born from mothers with methemoglobinemia. Our hypothesis suggests that prenatal iron abnormalities could lead to greater neuronal death, the disease ageing process, and neurodegenerative disorders such as AD and other neurodegenerative diseases.
文摘Objective To compare the phase radians in several cerebral regions between patients with Parkinson’s disease （PD） and control subjects, and to evaluate whether iron deposition quantified by susceptibility-weighted imaging （SWI） is related to the severity of motor symptoms of PD. Methods SWI consisted of both magnitude and phase images from a fully flow-compensated, 3-dimensional and gradient-echo （GRE） sequence. Magnitude and phase data were collected at GE HD 1.5T. The regions evaluated included frontal white matter, grey matter, cerebrospinal fluid, putamen, caudate nucleus （CN）, sub- stantia nigra pars compacta （SNc）, substantia nigra pars reticulata （SNr）, and red nucleus （RN）. A total number of 42 patients （12 patients without cognitive dysfunction, and 30 with cognitive dysfunction from mild to moderate degrees） and 30 control subjects were employed in the present study. Results The phase radians of SNc, CN and RN in PD patients were lower than those in control subjects （P〈0.05）. Conclusion The phase radians can be used to estimate the brain iron deposition in PD patients, which may be helpful in the diagnosis and longitudinal monitoring of PD.
