AIM:To translate the Glaucoma Quality of Life-15(GQL-15)to Serbian language and asses its validity and reliability in the population of Serbian patients.METHODS:The study included 177 glaucoma patients.Clinical pa...AIM:To translate the Glaucoma Quality of Life-15(GQL-15)to Serbian language and asses its validity and reliability in the population of Serbian patients.METHODS:The study included 177 glaucoma patients.Clinical parameters(visual acuity,mean defect and square root of loss variance of visual field)and socio-demographic data were collected.Patients were stratified according to the Nelson’s glaucoma staging system as mild,moderate and advanced glaucoma.All patients filled out the GQL-15 and National Eye Institute Visual Function Questionnaire(NEI-VFQ 25).The GQL-15 was translated following the internationally-accepted methodology,and its psychometric properties were assessed by using classical test theory and Rasch analysis.RESULTS:The mean total score for the GQL-15 was 20.68±7.31.The Cronbach’s alpha coefficient for the whole scale was 0.89(central and near vision,α=0.24;peripheral vision,α=0.85;glare and dark adaptation,α=0.83).Factor analysis established 4 factors(70.3% of variance):two corresponding to the original factors and two new factors specific for the Serbian population.The GQL-15 score correlated positively with almost all clinical parameters and NEI-VFQ 25 proving good criterion validity.Correlation of the GQL-15 total score on test-retest confirmed appropriate scale reproducibility(ρ=0.96,P〈0.001).The GQL-15 discriminated well advanced from mild and moderate glaucoma.In Rasch analysis we obtained adequate item(0.95)reliability index.Almost all items had infit and outfit mean squares in the accepted range.CONCLUSION:Serbian version of the GQL-15 demonstrates adequate reliability and validity.This version of the GQL-15is a valid instrument for evaluation of quality of life among Serbian speaking patients with glaucoma and can be applied in daily clinical work.展开更多
目的:评价原发性开角型青光眼(primary open angle glaucoma,POAG)患者的心理和生活质量状况并分析其影响因素。方法:采用前瞻性临床对照的方法,对60例POAG患者分别采用青光眼生活质量-15中文版(Glaucoma Quality of Life-15,GQL-15)和...目的:评价原发性开角型青光眼(primary open angle glaucoma,POAG)患者的心理和生活质量状况并分析其影响因素。方法:采用前瞻性临床对照的方法,对60例POAG患者分别采用青光眼生活质量-15中文版(Glaucoma Quality of Life-15,GQL-15)和综合医院焦虑抑郁量表(Hospital Anxiety and Depression Scale,HADS)中文版评定患者最近1mo的生活质量和焦虑、抑郁状况,给予降压药物干预后1mo再次进行评定。60例健康自愿者作为对照,分析其心理和生活质量变化情况。结果:POAG患者焦虑、抑郁及共患患者发生率分别为33.3%,26.7%,13.4%。患者抑郁焦虑评分及GQL评分与病程、眼压、年龄、药物种类和价格成正相关(P<0.05),与平均月收入、视力成负相关(P<0.05)。通过降压药物干预,患者焦虑、抑郁评分及生活质量评分明显好转(F焦虑评分=9.54,F抑郁评分=6.88,FGQL评分=8.82;P<0.05)。结论:POAG患者焦虑、抑郁状况加重,生活质量明显降低。患者抑郁焦虑评分及生活质量评分与病程、年龄、平均月收入、药物种类、药物价格、视力、眼压、视野等方面紧密相关。降压药物干预有助于青光眼患者生活质量和心理逐步康复。展开更多
文摘AIM:To translate the Glaucoma Quality of Life-15(GQL-15)to Serbian language and asses its validity and reliability in the population of Serbian patients.METHODS:The study included 177 glaucoma patients.Clinical parameters(visual acuity,mean defect and square root of loss variance of visual field)and socio-demographic data were collected.Patients were stratified according to the Nelson’s glaucoma staging system as mild,moderate and advanced glaucoma.All patients filled out the GQL-15 and National Eye Institute Visual Function Questionnaire(NEI-VFQ 25).The GQL-15 was translated following the internationally-accepted methodology,and its psychometric properties were assessed by using classical test theory and Rasch analysis.RESULTS:The mean total score for the GQL-15 was 20.68±7.31.The Cronbach’s alpha coefficient for the whole scale was 0.89(central and near vision,α=0.24;peripheral vision,α=0.85;glare and dark adaptation,α=0.83).Factor analysis established 4 factors(70.3% of variance):two corresponding to the original factors and two new factors specific for the Serbian population.The GQL-15 score correlated positively with almost all clinical parameters and NEI-VFQ 25 proving good criterion validity.Correlation of the GQL-15 total score on test-retest confirmed appropriate scale reproducibility(ρ=0.96,P〈0.001).The GQL-15 discriminated well advanced from mild and moderate glaucoma.In Rasch analysis we obtained adequate item(0.95)reliability index.Almost all items had infit and outfit mean squares in the accepted range.CONCLUSION:Serbian version of the GQL-15 demonstrates adequate reliability and validity.This version of the GQL-15is a valid instrument for evaluation of quality of life among Serbian speaking patients with glaucoma and can be applied in daily clinical work.
文摘目的:评价原发性开角型青光眼(primary open angle glaucoma,POAG)患者的心理和生活质量状况并分析其影响因素。方法:采用前瞻性临床对照的方法,对60例POAG患者分别采用青光眼生活质量-15中文版(Glaucoma Quality of Life-15,GQL-15)和综合医院焦虑抑郁量表(Hospital Anxiety and Depression Scale,HADS)中文版评定患者最近1mo的生活质量和焦虑、抑郁状况,给予降压药物干预后1mo再次进行评定。60例健康自愿者作为对照,分析其心理和生活质量变化情况。结果:POAG患者焦虑、抑郁及共患患者发生率分别为33.3%,26.7%,13.4%。患者抑郁焦虑评分及GQL评分与病程、眼压、年龄、药物种类和价格成正相关(P<0.05),与平均月收入、视力成负相关(P<0.05)。通过降压药物干预,患者焦虑、抑郁评分及生活质量评分明显好转(F焦虑评分=9.54,F抑郁评分=6.88,FGQL评分=8.82;P<0.05)。结论:POAG患者焦虑、抑郁状况加重,生活质量明显降低。患者抑郁焦虑评分及生活质量评分与病程、年龄、平均月收入、药物种类、药物价格、视力、眼压、视野等方面紧密相关。降压药物干预有助于青光眼患者生活质量和心理逐步康复。