In the next three to five years, China’s light industry will upgrade major product quality generally to world level. This will be done by strengthening quality control and supervision and the improvement in technolog...In the next three to five years, China’s light industry will upgrade major product quality generally to world level. This will be done by strengthening quality control and supervision and the improvement in technology. The campaign was announced by Yu Zhen, president of the China National Council of Light Industry at the beginning of this year.展开更多
The quality control system for meteorological real-time data from automatic weather stations in Shandong realized integration of communi- cation system and provincial quality control system, and an interaction platfor...The quality control system for meteorological real-time data from automatic weather stations in Shandong realized integration of communi- cation system and provincial quality control system, and an interaction platform which was mainly created by Web was set up. The system not only was fully guaranteed for the funning of basic business, also improved the reliability of the data.展开更多
The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow.Mitochondria are directly affected by direct facto...The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow.Mitochondria are directly affected by direct factors such as ischemia,hypoxia,excitotoxicity,and toxicity of free hemoglobin and its degradation products,which trigger mitochondrial dysfunction.Dysfunctional mitochondria release large amounts of reactive oxygen species,inflammatory mediators,and apoptotic proteins that activate apoptotic pathways,further damaging cells.In response to this array of damage,cells have adopted multiple mitochondrial quality control mechanisms through evolution,including mitochondrial protein quality control,mitochondrial dynamics,mitophagy,mitochondrial biogenesis,and intercellular mitochondrial transfer,to maintain mitochondrial homeostasis under pathological conditions.Specific interventions targeting mitochondrial quality control mechanisms have emerged as promising therapeutic strategies for subarachnoid hemorrhage.This review provides an overview of recent research advances in mitochondrial pathophysiological processes after subarachnoid hemorrhage,particularly mitochondrial quality control mechanisms.It also presents potential therapeutic strategies to target mitochondrial quality control in subarachnoid hemorrhage.展开更多
An integral quality control(QC)procedure that integrates various QC methods and considers the design indexes and operational status of the instruments for the observations of drifting air-sea interface buoy was develo...An integral quality control(QC)procedure that integrates various QC methods and considers the design indexes and operational status of the instruments for the observations of drifting air-sea interface buoy was developed in the order of basic in-spection followed by targeted QC.The innovative method of combining a moving Hampel filter and local anomaly detection com-plies with statistical laws and physical processes,which guarantees the QC performance of meteorological variables.Two sets of observation data were used to verify the applicability and effectiveness of the QC procedure,and the effect was evaluated using the observations of the Kuroshio Extension Observatory buoy as the reference.The results showed that the outliers in the time series can be correctly identified and processed,and the quality of data improved significantly.The linear correlation between the quality-controlled observations and the reference increased,and the difference decreased.The correlation coefficient of wind speed before and after QC increased from 0.77 to 0.82,and the maximum absolute error decreased by approximately 2.8ms^(-1).In addition,air pressure and relative humidity were optimized by 10^(-3)–10^(-2) orders of magnitude.For the sea surface temperature,the weight of coefficients of the continuity test algorithm was optimized based on the sea area of data acquisition,which effectively expanded the applicability of the algorithm.展开更多
PDI is a molecular chaperone and plays an important role in Endoplasmic Reticulum quality control (ERQC).PDI participates in the refolding of the misfolded/unfolded proteins to maintain cellular homeostasis under diff...PDI is a molecular chaperone and plays an important role in Endoplasmic Reticulum quality control (ERQC).PDI participates in the refolding of the misfolded/unfolded proteins to maintain cellular homeostasis under differentstresses. However, bioinformatic characteristics and potential functions of PDIs in diatom Phaeodactylumtricornutum (Pt) are still unknown so far. Hence, the genome-wide characteristics of PtPDI proteins in P. tricornutumwere first studied via bioinformatic and transcriptomic methods. 42 PtPDI genes were identified from thegenome of P. tricornutum. The motif, protein structure, classification, number of introns, phylogenetic relationship,and the expression level of 42 PtPDI genes under the tunicamycin stress were analyzed. A pair of tandemduplicated genes (PtPDI15 and PtPDI18) was observed in P. tricornutum. The 42 PtPDIs with different genecharacteristics were divided into three independent clades, indicating different evolutional relationships and functionsof these PtPDIs. The 14 up-regulated PtPDI genes under the tunicamycin treatment might have a positiveeffect on the ER quality control of the unfolded/misfolded proteins, while the 7 down-regulated PtPDIs mightnegatively affect the ERQC. The characteristics of all 42 PtPDIs and their proposed working model here providea comprehensive understanding of the PtPDIs gene family. The differential expression of 21 PtPDIs will be usefulfor further functional study in the ERQC.展开更多
Objective: To explore the effect of evidence-based quality control circle (QCC) in improving the implementation rate of airway management measures in adult critically ill patients. Methods: Based on the Joanna Briggs ...Objective: To explore the effect of evidence-based quality control circle (QCC) in improving the implementation rate of airway management measures in adult critically ill patients. Methods: Based on the Joanna Briggs Institute (JBI) evidence-based health care model, the best evidence of airway management in adult critically ill patients was obtained and applied to the clinic. Results: The total implementation rate of airway management measures in adult critically ill patients increased from 23.62% before the implementation of quality control circle to 88.82%, and the pulmonary infection rate in critically ill patients decreased from 42.31% to 21.74%, with statistical significance between the two groups (P 0.05). Conclusion: Evidence-based quality control circle activities can standardize the practice standards of airway management in critically ill patients, reduce the occurrence of patients’ airway related complications, and improve clinical outcomes.展开更多
Objective:To evaluate the application value of a refined quality control management model for a sterilization supply center.Methods:A retrospective analysis was conducted on the work situation of the sterilization sup...Objective:To evaluate the application value of a refined quality control management model for a sterilization supply center.Methods:A retrospective analysis was conducted on the work situation of the sterilization supply center from January 2021 to January 2023.The work situation before January 31,2022,was classified as the control group;a routine quality control management model was implemented,and the work situation after January 31,2022,was classified as the observation group.The quality of medical device management and department satisfaction between the two groups were compared.Results:The timely recovery and supply rate,classification and cleaning pass rate,disinfection pass rate,packaging pass rate,sterilization pass rate,and department satisfaction score in the observation group were all higher than those of the control group(P<0.05).Conclusion:Implementing a refined quality control management model in the sterilization supply center can improve the quality management level of medical devices and department satisfaction and is worthy of promotion.展开更多
In the era of big data,the construction and implementation of a quality control audit system are particularly crucial.This article delves into the impact of big data technology on quality control auditing,establishes ...In the era of big data,the construction and implementation of a quality control audit system are particularly crucial.This article delves into the impact of big data technology on quality control auditing,establishes a quality control auditing system in the big data era,and elucidates the pathway to realizing this system.Through the application of big data technology to quality control audits,there is an enhancement in audit efficiency,the attainment of more accurate risk assessment,and the provision of robust support for the sustainable development of enterprises.展开更多
Fingerprint evidence played an important role in investigation,prosecution,and trial process due to the belief of its uniqueness and unchanged characteristics.However,in recent years,the science behind the process of ...Fingerprint evidence played an important role in investigation,prosecution,and trial process due to the belief of its uniqueness and unchanged characteristics.However,in recent years,the science behind the process of fingerprint comparisons has been questioned.Main research questions have been focusing on the opaqueness within the comparison processes,subjective judgments,lack of universal standards,no error rate expression on final conclusions,and poor scientific fundamental research data.Facing the above-mentioned questions,this paper aims to suggest a quality control system(QCS)for fingerprint comparison processes.This QCS is based on the use of software(PiAnoS)and its technological features,being able to provide a data management model to increase the transparency and quality of fingerprint comparison processes.展开更多
This study aims to investigate the phenomenon of technological gadget usage among pre-university students,which include the time spent using them,as well as their purpose and influence.A descriptive research design was...This study aims to investigate the phenomenon of technological gadget usage among pre-university students,which include the time spent using them,as well as their purpose and influence.A descriptive research design was adopted in this study.131 pre-university students were randomly selected to answer a structured questionnaire.They were informed two weeks earlier to keep track on their time spent on technological devices,before answering the questionnaire.Findings showed that 99.2%of the respondents owned at least two technological gadgets,and all respondents own a smartphone.The main two gadgets that respondents spend at least 4 h a day on are smartphones(65.6%)and computers/laptops(21.4%).This indicates that smartphones are commonly used and owned among the respondents.The majority of the respondents are moderately nomophobia and moderately dependent on smartphones(70.2%and 66.4%,respectively).Correlation analysis demonstrates that the total time spent on gadgets in a day has a significant positive correlation with gadget dependency and total number of gadgets owned.Meanwhile,logistic regression was conducted to estimate the probability of nomophobia and dependency using total time spent and total number of technological gadgets.From thefindings,it was demonstrated that when the total time spent on using technological gadgets increasing,there is greater probability that the respondents develop nomophobia and dependency.This indicates that nomophobia and dependency to technological gadgets can be used to predict lifestyle profiles.The use of technological gadgets can bring both benefit and harm to its user.In light of this,user has to remain rational in order to derive maximum benefit from it.展开更多
Aim: To evaluate the effects of retrospective quality control on pressure-flow data with computer-based urodynamic systems from men with benign prostatic hyperplasia (BPH). Methods: A total of 582 traces of pressu...Aim: To evaluate the effects of retrospective quality control on pressure-flow data with computer-based urodynamic systems from men with benign prostatic hyperplasia (BPH). Methods: A total of 582 traces of pressure-flow study from 181 men with BPH was included in the study. For each trace, maximum urinary flow rate (Qmax) and detrusor pressure at Qmax (pdet.Qmax) were, respectively, read from manually smoothed and corrected uroflow and detrusor pressure curves from the computer print-outs. Obstruction coefficient, International Continence Society (ICS) and Schaefer nomograms were used to detect urethral resistance and to diagnose obstruction. The results obtained by manual reading were compared with those from computer-based systems. Results: After manual correction, Qmax underwent a consistently significant decrease by 1.2 mL/s on average (P 〈 0.001), and had a change range of 0.5-10.4 mL/s. However, pdet.Qmax underwent inconsistently intra-individual changes after correction. The obstruction coefficient increased significantly, by an average of 0.07 (P 〈 0.05). Using the ICS nomogram, the percentage of obstruction increased from 69.8% to 73.9%, and of the non-obstruction decreased from 8.8% to 5.3% (P 〈 0.05). There were 11% of traces that changed the classifications using the ICS nomogram, and 28.9% that changed the grades for the Schaefer nomogram. Conclusion: Systematically significant differences in parameters from pres- sure-flow study between manual readings and computer recordings were demonstrated. Manual correction resulted in a consistently lower Q a higher urethral resistance, and an aggravating obstruction. Manual readings can correct considerable false diagnoses for obstruction. Retrospective quality control of pressure-flow data with com- puter-based systems is necessary.展开更多
[Objectives]To establish a HPLC characteristic spectrum of honeysuckle stem formula granules,and to evaluate the quality consistency based on the standard decoction.[Methods]Using Agilent ZORBAX SB-C_(18)(5μm,250 mm&...[Objectives]To establish a HPLC characteristic spectrum of honeysuckle stem formula granules,and to evaluate the quality consistency based on the standard decoction.[Methods]Using Agilent ZORBAX SB-C_(18)(5μm,250 mm×4.6 mm)chromatographic column;gradient elution with acetonitrile-0.4%phosphoric acid solution(0.2:99.8,V/V),column temperature at 25℃;detection wavelength at 236 nm;flow rate 1.0 mL/min;using"Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine",to evaluate the similarity of the characteristic chromatogram of crude drug,standard decoction and formula granules of honeysuckle stem.[Results]The similarity of characteristic chromatogram was higher than 0.94,and 6 components were identified from 10 characteristic peaks.[Conclusions]The established method can more comprehensively reflect the overall appearance of the chemical substances in the honeysuckle stem and the transmission law,and can provide an experimental basis for the consistency of the quality of the honeysuckle stem formula granules.展开更多
[Objectives]To establish the TLC identification methods of Llicis Rotundae Cortex and Mahoniae Caulis and the determination method of syringin content in Zhuang Medicine Xiaoyan Zhiyang Lotion.[Methods]Thin layer chro...[Objectives]To establish the TLC identification methods of Llicis Rotundae Cortex and Mahoniae Caulis and the determination method of syringin content in Zhuang Medicine Xiaoyan Zhiyang Lotion.[Methods]Thin layer chromatography(TLC)was used to qualitatively identify Llicis Rotundae Cortex and Mahoniae Caulis in Zhuang Medicine Xiaoyan Zhiyang Lotion.The quantitative analysis of syringin in Zhuang Medicine Xiaoyan Zhiyang Lotion was carried out by high-performance liquid chromatography(HPLC).Chromatographic conditions are as follows:Luna 5μm C_(18)((2)100 A(250 mm×4.6 mm,5μm)column was adopted;acetonitrile(10%)-water(90%)was as the mobile phase,and the flow rate was 1.0 mL/min;the detection wavelength was 265 nm;the sample size was 5μL;the column temperature was 30℃.[Results]Syringin had a good linear relationship with its peak area in the range of 0.190-2.856μg(R^(2)=0.9995).The RSD values of precision,stability and repeatability experiments were all lower than 2.5%,and the average sampling recovery rate(n=6)was 100.37%(RSD=-0.88%).[Conclusions]The method had the advantages of simple operation,strong specificity,good repeatability and stability,and can be used for the quality control of Zhuang Medicine Xiaoyan Zhiyang Lotion.展开更多
Corydalis bungeana Turcz.(CB)is a medicinal herb with significant medicinal value in traditional Chinese medicine.This paper reviews the progress of research on CB’s botany,quality control,phytochemistry,pharmacology...Corydalis bungeana Turcz.(CB)is a medicinal herb with significant medicinal value in traditional Chinese medicine.This paper reviews the progress of research on CB’s botany,quality control,phytochemistry,pharmacology and toxicity.The plant’s information was gathered from scientific databases such as PubMed,GeenMedical,Springer Link(https://link.springer.com),Chinese National Knowledge Infrastructure,Pharmacopoeia and Flora.Currently,137 phytochemicals have been identified and isolated from CB,including alkaloids,flavonoids,amino acids,terpenoids,coumarins and organic acids.In addition,many phytochemicals reported various antiinflammatory,antibacterial,antiviral,antitumor,analgesic,hepatoprotective,immunomodulatory,neuromodulatory,and lipid reduction activities.However,the study of its toxicity is still at the preliminary exploration stage and needs further intensive exploration.Herein,we provide an in-depth investigation of the progress of CB to elucidate the underlying mechanisms of activity of CB extracts and its major components,deliver valuable resources and information for further research and rational drug use,and explore the potential research directions and prospects of CB.展开更多
The existence of outliers can seriously influence the analysis of variational data assimilation.Quality control allows us to effectively eliminate or absorb these outliers to produce better analysis fields.In particul...The existence of outliers can seriously influence the analysis of variational data assimilation.Quality control allows us to effectively eliminate or absorb these outliers to produce better analysis fields.In particular,variational quality control(VarQC) can process gray zone outliers and is thus broadly used in variational data assimilation systems.In this study,governing equations are derived for two VarQC algorithms that utilize different contaminated Gaussian distributions(CGDs): Gaussian plus flat distribution and Huber norm distribution.As such,these VarQC algorithms can handle outliers that have non-Gaussian innovations.Then,these VarQC algorithms are implemented in the Global/Regional Assimilation and PrEdiction System(GRAPES) model-level three-dimensional variational data assimilation(m3 DVAR) system.Tests using artificial observations indicate that the VarQC method using the Huber distribution has stronger robustness for including outliers to improve posterior analysis than the VarQC method using the Gaussian plus flat distribution.Furthermore,real observation experiments show that the distribution of observation analysis weights conform well with theory,indicating that the application of VarQC is effective in the GRAPES m3 DVAR system.Subsequent case study and longperiod data assimilation experiments show that the spatial distribution and amplitude of the observation analysis weights are related to the analysis increments of the mass field(geopotential height and temperature).Compared to the control experiment,VarQC experiments have noticeably better posterior mass fields.Finally,the VarQC method using the Huber distribution is superior to the VarQC method using the Gaussian plus flat distribution,especially at the middle and lower levels.展开更多
WHO strategy on traditional medicine is based on security and quality of phytomedicine. Commonly adulterated affecting mostly metabolic and sexual dysfunction drugs. Control quality of those phytomedicines requires de...WHO strategy on traditional medicine is based on security and quality of phytomedicine. Commonly adulterated affecting mostly metabolic and sexual dysfunction drugs. Control quality of those phytomedicines requires development of strategy and techniques applicable to them. Among the techniques, Reverse Phase Liquid Chromatography is the most used and has been developed in these studies to assess a protocol to characterize Gardenia aqualla leaves extract. The method consists in determining chromatographic conditions using organic and pH gradient models based on water and acetonitrile combined with pH modifiers made up of formic acid (AF) and ammonium hydroxide (NH<sub>3</sub>). Results show that extracts contain mainly acidic compounds quickly eluted by NH<sub>3</sub> and more retained by AF. Optimal pH range for separation is 3 - 7 corresponding to 1.59 mM of NH<sub>3</sub> and 6.55 mM of AF. In these conditions, elution of many polar compounds could be effective using a C18 based-deactivated column in a short period of time.展开更多
Background:Good adherence to post-operative exercise is crucial for long-term exercise intervention programs aimed at improving compliance,motivation for functional exercise,and quality of life among breast cancer pat...Background:Good adherence to post-operative exercise is crucial for long-term exercise intervention programs aimed at improving compliance,motivation for functional exercise,and quality of life among breast cancer patients.This study aims to evaluate the application effect of quality control circles on postoperative functional exercise compliance in breast neoplasm patients.Methods:A comprehensive search was conducted in CNKI,Wanfang,VIP,CBM,PubMed,Cochrane Library,Web of Science and CINAHL databases from their establishment to May 06,2023.Manual search and backtracking of relevant literature were also conducted.The search terms included a combination of subject terms and free words.Meta-analysis was performed using RevMan 5.4 software on eligible literature.Results:Initially,517 papers were retrieved,and after removing duplicates 238 papers using NoteExpress software,279 titles and abstracts were reviewed.Subsequently,225 non-compliant papers were excluded,leaving 54 full texts to be read.After excluding 38 non-compliant papers,16 eligible papers were included for Meta-analysis.These papers comprised a total of 1,342 patients(679 in the test group and 663 in the control group).The heterogeneity test using a fixed effects model showed P=0.22 and I2=21%.The Meta-analysis results demonstrated that the implementation of quality control circles alongside usual care significantly improved compliance with postoperative functional exercise in breast cancer patients(odds ratio=6.68,95%confidence interval(4.97,8.98),P<0.00001).Conclusion:Quality control circles activities can effectively enhance compliance with post-operative functional exercise among breast cancer patients,aiding in the recovery of affected limb function,improvement of self-care ability,and early reintegration into society and normal life,thereby enhancing quality of life.It is important to continually accumulate experience in applying relevant quality control circles activities in clinical work and promptly enhance the level of care accordingly,as the functional exercise of breast cancer patients after surgery involves a long-term and gradual improvement process.展开更多
Objective: To carry out empirical research on the role of project-achieving quality control circle (QCC) in constructing a new model of contactless medical service for outpatients. Methods: A QCC, consisting of inform...Objective: To carry out empirical research on the role of project-achieving quality control circle (QCC) in constructing a new model of contactless medical service for outpatients. Methods: A QCC, consisting of information office members from a grade A tertiary hospital in Wenzhou, was established to conduct a research project with the theme “Constructing a new model of contactless medical service based on outpatients’ experience.” According to the ten steps and PDCA cycle, an analysis was carried out before and after the QCC activities, focusing on improving pre-consultation services, providing steward-like services, and facilitating post-consultation management. Results: After the QCC activities, the mobile appointment rate, missed appointment rate, the proportion of smart check-ins, and the average check-in time were 55.68%, 4.02%, 39.75%, and 8.24 ± 3.66 min, respectively;in contrast, before the activities, they were 32.00%, 7.88%, 0.00%, and 14.96 ± 4.98 min, respectively;the difference between the two groups was statistically significant (χ2 = 3480.112, 4994.496;Fisher’s exact probability = 963788.570;t = 5.323, P < 0.001). Many experts have also visited the hospital to learn about this system, thus rendering social and economic benefits. Conclusion: Project-achieving QCC activities are suitable for complex situations, such as constructing a new model of contactless medical service, and can significantly improve outpatient service quality, enhance patients’ experience, and improve the abilities of circle members.展开更多
In view of social development,the demand for water conservancy engineering applications continues to increase.The number and scale of water conservancy projects in China have been in a state of continuous expansion in...In view of social development,the demand for water conservancy engineering applications continues to increase.The number and scale of water conservancy projects in China have been in a state of continuous expansion in recent years.As a result,how to achieve efficient testing and effective control of the quality of water conservancy projects has always been a topic of discussion in the field of water conservancy engineering in our country.This paper summarizes the application of non-destructive testing technology in the quality testing and control of water conservancy projects.On the basis of explaining the connotation and application advantages of non-destructive testing technology,the non-destructive testing application strategies for concrete strength,steel corrosion and shallow cracks in water conservancy projects were studied.展开更多
Objective:To analyze the effect of quality control circle on the central sterile supply department(CSSD).Methods:The control group and the observation group each consisted of 180 instruments received by the sterilizat...Objective:To analyze the effect of quality control circle on the central sterile supply department(CSSD).Methods:The control group and the observation group each consisted of 180 instruments received by the sterilization supply center from January to March 2023 and 11 CSSD staff.The control group underwent routine management while quality control circle was implemented in the observation group.The quality of work,disinfection and sterilization qualification rates,disinfection and sterilization of various instruments,cleaning indicators,and management satisfaction of both groups were compared.Results:The observation group scored higher in terms of work quality,the qualification rate of disinfection and sterilization in each link,the disinfection and sterilization of instruments,and cleaning indicators compared to the control group.Besides,the management satisfaction of the observation group was higher than that of the control group(P<0.05).Conclusion:A quality control circle ensures the quality of work,improves the cleaning,disinfection,and sterilization of instruments of the CSSD,and improves the management satisfaction of the CSSD staff.展开更多
文摘In the next three to five years, China’s light industry will upgrade major product quality generally to world level. This will be done by strengthening quality control and supervision and the improvement in technology. The campaign was announced by Yu Zhen, president of the China National Council of Light Industry at the beginning of this year.
文摘The quality control system for meteorological real-time data from automatic weather stations in Shandong realized integration of communi- cation system and provincial quality control system, and an interaction platform which was mainly created by Web was set up. The system not only was fully guaranteed for the funning of basic business, also improved the reliability of the data.
基金supported by the National Natural Science Foundation of China,Nos.82130037(to CH),81971122(to CH),82171323(to WL)the Natural Science Foundation of Jiangsu Province of China,No.BK20201113(to WL)。
文摘The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow.Mitochondria are directly affected by direct factors such as ischemia,hypoxia,excitotoxicity,and toxicity of free hemoglobin and its degradation products,which trigger mitochondrial dysfunction.Dysfunctional mitochondria release large amounts of reactive oxygen species,inflammatory mediators,and apoptotic proteins that activate apoptotic pathways,further damaging cells.In response to this array of damage,cells have adopted multiple mitochondrial quality control mechanisms through evolution,including mitochondrial protein quality control,mitochondrial dynamics,mitophagy,mitochondrial biogenesis,and intercellular mitochondrial transfer,to maintain mitochondrial homeostasis under pathological conditions.Specific interventions targeting mitochondrial quality control mechanisms have emerged as promising therapeutic strategies for subarachnoid hemorrhage.This review provides an overview of recent research advances in mitochondrial pathophysiological processes after subarachnoid hemorrhage,particularly mitochondrial quality control mechanisms.It also presents potential therapeutic strategies to target mitochondrial quality control in subarachnoid hemorrhage.
基金supported by the Natural Resources Development Special Fund Project of Jiangsu Province(No.JSZRHYKJ202009)the Taishan Scholar Funds(No.tsqn 201812022)+2 种基金the Fundamental Research Funds for the Central Universities(No.202072001)the Guangxi Key Laboratory of Marine Disaster in the Beibu Gulf,Beibu Gulf University(No.2021KF03)the National Natural Science Foundation of China(No.42176020).
文摘An integral quality control(QC)procedure that integrates various QC methods and considers the design indexes and operational status of the instruments for the observations of drifting air-sea interface buoy was developed in the order of basic in-spection followed by targeted QC.The innovative method of combining a moving Hampel filter and local anomaly detection com-plies with statistical laws and physical processes,which guarantees the QC performance of meteorological variables.Two sets of observation data were used to verify the applicability and effectiveness of the QC procedure,and the effect was evaluated using the observations of the Kuroshio Extension Observatory buoy as the reference.The results showed that the outliers in the time series can be correctly identified and processed,and the quality of data improved significantly.The linear correlation between the quality-controlled observations and the reference increased,and the difference decreased.The correlation coefficient of wind speed before and after QC increased from 0.77 to 0.82,and the maximum absolute error decreased by approximately 2.8ms^(-1).In addition,air pressure and relative humidity were optimized by 10^(-3)–10^(-2) orders of magnitude.For the sea surface temperature,the weight of coefficients of the continuity test algorithm was optimized based on the sea area of data acquisition,which effectively expanded the applicability of the algorithm.
基金the funding of Educational and Scientific Research Projects for Young and Middle-Aged Teachers in Fujian Province(Grant Number:2022JAT220693)Natural Science Foundation of Guangdong Province(Grant Number:2022A1515012141)+2 种基金the Program for University Innovation Team of Guangdong Province(Grant Number:2022KCXTD008)National Natural Science Foundation of China(92158201 and 42376001)the Innovation and Entrepreneurship Project of Shantou(201112176541391).
文摘PDI is a molecular chaperone and plays an important role in Endoplasmic Reticulum quality control (ERQC).PDI participates in the refolding of the misfolded/unfolded proteins to maintain cellular homeostasis under differentstresses. However, bioinformatic characteristics and potential functions of PDIs in diatom Phaeodactylumtricornutum (Pt) are still unknown so far. Hence, the genome-wide characteristics of PtPDI proteins in P. tricornutumwere first studied via bioinformatic and transcriptomic methods. 42 PtPDI genes were identified from thegenome of P. tricornutum. The motif, protein structure, classification, number of introns, phylogenetic relationship,and the expression level of 42 PtPDI genes under the tunicamycin stress were analyzed. A pair of tandemduplicated genes (PtPDI15 and PtPDI18) was observed in P. tricornutum. The 42 PtPDIs with different genecharacteristics were divided into three independent clades, indicating different evolutional relationships and functionsof these PtPDIs. The 14 up-regulated PtPDI genes under the tunicamycin treatment might have a positiveeffect on the ER quality control of the unfolded/misfolded proteins, while the 7 down-regulated PtPDIs mightnegatively affect the ERQC. The characteristics of all 42 PtPDIs and their proposed working model here providea comprehensive understanding of the PtPDIs gene family. The differential expression of 21 PtPDIs will be usefulfor further functional study in the ERQC.
文摘Objective: To explore the effect of evidence-based quality control circle (QCC) in improving the implementation rate of airway management measures in adult critically ill patients. Methods: Based on the Joanna Briggs Institute (JBI) evidence-based health care model, the best evidence of airway management in adult critically ill patients was obtained and applied to the clinic. Results: The total implementation rate of airway management measures in adult critically ill patients increased from 23.62% before the implementation of quality control circle to 88.82%, and the pulmonary infection rate in critically ill patients decreased from 42.31% to 21.74%, with statistical significance between the two groups (P 0.05). Conclusion: Evidence-based quality control circle activities can standardize the practice standards of airway management in critically ill patients, reduce the occurrence of patients’ airway related complications, and improve clinical outcomes.
文摘Objective:To evaluate the application value of a refined quality control management model for a sterilization supply center.Methods:A retrospective analysis was conducted on the work situation of the sterilization supply center from January 2021 to January 2023.The work situation before January 31,2022,was classified as the control group;a routine quality control management model was implemented,and the work situation after January 31,2022,was classified as the observation group.The quality of medical device management and department satisfaction between the two groups were compared.Results:The timely recovery and supply rate,classification and cleaning pass rate,disinfection pass rate,packaging pass rate,sterilization pass rate,and department satisfaction score in the observation group were all higher than those of the control group(P<0.05).Conclusion:Implementing a refined quality control management model in the sterilization supply center can improve the quality management level of medical devices and department satisfaction and is worthy of promotion.
文摘In the era of big data,the construction and implementation of a quality control audit system are particularly crucial.This article delves into the impact of big data technology on quality control auditing,establishes a quality control auditing system in the big data era,and elucidates the pathway to realizing this system.Through the application of big data technology to quality control audits,there is an enhancement in audit efficiency,the attainment of more accurate risk assessment,and the provision of robust support for the sustainable development of enterprises.
基金This paper was supported by award number 71371188(on evidence evaluation model and its application,a study based on decision-making in management and court)funded by China National Natural Science Fund and Award number 2016XCWZK08 funded by Shanghai Key Laboratory of Crime Scene Evidence.
文摘Fingerprint evidence played an important role in investigation,prosecution,and trial process due to the belief of its uniqueness and unchanged characteristics.However,in recent years,the science behind the process of fingerprint comparisons has been questioned.Main research questions have been focusing on the opaqueness within the comparison processes,subjective judgments,lack of universal standards,no error rate expression on final conclusions,and poor scientific fundamental research data.Facing the above-mentioned questions,this paper aims to suggest a quality control system(QCS)for fingerprint comparison processes.This QCS is based on the use of software(PiAnoS)and its technological features,being able to provide a data management model to increase the transparency and quality of fingerprint comparison processes.
基金the Universiti Kebangsaan Malaysia,Geran Galakan Penyelidikan,GGP-2020-040.
文摘This study aims to investigate the phenomenon of technological gadget usage among pre-university students,which include the time spent using them,as well as their purpose and influence.A descriptive research design was adopted in this study.131 pre-university students were randomly selected to answer a structured questionnaire.They were informed two weeks earlier to keep track on their time spent on technological devices,before answering the questionnaire.Findings showed that 99.2%of the respondents owned at least two technological gadgets,and all respondents own a smartphone.The main two gadgets that respondents spend at least 4 h a day on are smartphones(65.6%)and computers/laptops(21.4%).This indicates that smartphones are commonly used and owned among the respondents.The majority of the respondents are moderately nomophobia and moderately dependent on smartphones(70.2%and 66.4%,respectively).Correlation analysis demonstrates that the total time spent on gadgets in a day has a significant positive correlation with gadget dependency and total number of gadgets owned.Meanwhile,logistic regression was conducted to estimate the probability of nomophobia and dependency using total time spent and total number of technological gadgets.From thefindings,it was demonstrated that when the total time spent on using technological gadgets increasing,there is greater probability that the respondents develop nomophobia and dependency.This indicates that nomophobia and dependency to technological gadgets can be used to predict lifestyle profiles.The use of technological gadgets can bring both benefit and harm to its user.In light of this,user has to remain rational in order to derive maximum benefit from it.
文摘Aim: To evaluate the effects of retrospective quality control on pressure-flow data with computer-based urodynamic systems from men with benign prostatic hyperplasia (BPH). Methods: A total of 582 traces of pressure-flow study from 181 men with BPH was included in the study. For each trace, maximum urinary flow rate (Qmax) and detrusor pressure at Qmax (pdet.Qmax) were, respectively, read from manually smoothed and corrected uroflow and detrusor pressure curves from the computer print-outs. Obstruction coefficient, International Continence Society (ICS) and Schaefer nomograms were used to detect urethral resistance and to diagnose obstruction. The results obtained by manual reading were compared with those from computer-based systems. Results: After manual correction, Qmax underwent a consistently significant decrease by 1.2 mL/s on average (P 〈 0.001), and had a change range of 0.5-10.4 mL/s. However, pdet.Qmax underwent inconsistently intra-individual changes after correction. The obstruction coefficient increased significantly, by an average of 0.07 (P 〈 0.05). Using the ICS nomogram, the percentage of obstruction increased from 69.8% to 73.9%, and of the non-obstruction decreased from 8.8% to 5.3% (P 〈 0.05). There were 11% of traces that changed the classifications using the ICS nomogram, and 28.9% that changed the grades for the Schaefer nomogram. Conclusion: Systematically significant differences in parameters from pres- sure-flow study between manual readings and computer recordings were demonstrated. Manual correction resulted in a consistently lower Q a higher urethral resistance, and an aggravating obstruction. Manual readings can correct considerable false diagnoses for obstruction. Retrospective quality control of pressure-flow data with com- puter-based systems is necessary.
基金Supported by Major Project of Nanning Scientific Research and Technology Development Plan in 2020(20201048)。
文摘[Objectives]To establish a HPLC characteristic spectrum of honeysuckle stem formula granules,and to evaluate the quality consistency based on the standard decoction.[Methods]Using Agilent ZORBAX SB-C_(18)(5μm,250 mm×4.6 mm)chromatographic column;gradient elution with acetonitrile-0.4%phosphoric acid solution(0.2:99.8,V/V),column temperature at 25℃;detection wavelength at 236 nm;flow rate 1.0 mL/min;using"Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine",to evaluate the similarity of the characteristic chromatogram of crude drug,standard decoction and formula granules of honeysuckle stem.[Results]The similarity of characteristic chromatogram was higher than 0.94,and 6 components were identified from 10 characteristic peaks.[Conclusions]The established method can more comprehensively reflect the overall appearance of the chemical substances in the honeysuckle stem and the transmission law,and can provide an experimental basis for the consistency of the quality of the honeysuckle stem formula granules.
基金Supported by the Key R&D Project of Guangxi Science and Technology Department(Guike AB21196057)Construction Project for High-level Key Discipline of Traditional Chinese Medicine(Zhuang Pharmacy)of the National Administration of Traditional Chinese Medicine([2022]No.226)+3 种基金Scientific Research Project of Guangxi Medical Products Administration(Name:Safety Evaluation of Zhuang Medicine Anti-inflammation and Antipruritic Prescription for the Treatment of Skin Diseases Such as Acute Eczema and Contact Dermatitis)Interdisciplinary Innovation Team Project of Traditional Chinese Medicine in Guangxi(GZKJ2309)Natural Science Foundation Project of Guangxi University of Chinese Medicine in 2021(2021MS045)"High-level Talent Cultivation Innovation Team"Funding Project of Guangxi University of Chinese Medicine(2022A008).
文摘[Objectives]To establish the TLC identification methods of Llicis Rotundae Cortex and Mahoniae Caulis and the determination method of syringin content in Zhuang Medicine Xiaoyan Zhiyang Lotion.[Methods]Thin layer chromatography(TLC)was used to qualitatively identify Llicis Rotundae Cortex and Mahoniae Caulis in Zhuang Medicine Xiaoyan Zhiyang Lotion.The quantitative analysis of syringin in Zhuang Medicine Xiaoyan Zhiyang Lotion was carried out by high-performance liquid chromatography(HPLC).Chromatographic conditions are as follows:Luna 5μm C_(18)((2)100 A(250 mm×4.6 mm,5μm)column was adopted;acetonitrile(10%)-water(90%)was as the mobile phase,and the flow rate was 1.0 mL/min;the detection wavelength was 265 nm;the sample size was 5μL;the column temperature was 30℃.[Results]Syringin had a good linear relationship with its peak area in the range of 0.190-2.856μg(R^(2)=0.9995).The RSD values of precision,stability and repeatability experiments were all lower than 2.5%,and the average sampling recovery rate(n=6)was 100.37%(RSD=-0.88%).[Conclusions]The method had the advantages of simple operation,strong specificity,good repeatability and stability,and can be used for the quality control of Zhuang Medicine Xiaoyan Zhiyang Lotion.
基金This research was funded by the National Natural Science Foundation of China(82260773)National Key R&D Program:Intergovernmental Cooperation in International Science and Technology Innovation(2022YFE0119300)+1 种基金Central Government Guided Local Scientific and Technological Development Project(2021ZY0015)Science and Technology Young Talents Development Project of Inner Mongolia Autonomous Region(NJYT22048).
文摘Corydalis bungeana Turcz.(CB)is a medicinal herb with significant medicinal value in traditional Chinese medicine.This paper reviews the progress of research on CB’s botany,quality control,phytochemistry,pharmacology and toxicity.The plant’s information was gathered from scientific databases such as PubMed,GeenMedical,Springer Link(https://link.springer.com),Chinese National Knowledge Infrastructure,Pharmacopoeia and Flora.Currently,137 phytochemicals have been identified and isolated from CB,including alkaloids,flavonoids,amino acids,terpenoids,coumarins and organic acids.In addition,many phytochemicals reported various antiinflammatory,antibacterial,antiviral,antitumor,analgesic,hepatoprotective,immunomodulatory,neuromodulatory,and lipid reduction activities.However,the study of its toxicity is still at the preliminary exploration stage and needs further intensive exploration.Herein,we provide an in-depth investigation of the progress of CB to elucidate the underlying mechanisms of activity of CB extracts and its major components,deliver valuable resources and information for further research and rational drug use,and explore the potential research directions and prospects of CB.
基金supported by the China Scholarship Councilprimarily sponsored by the National Key R&D Program of China (Grant No.2018YFC1506702 and Grant No.2017YFC1502000)。
文摘The existence of outliers can seriously influence the analysis of variational data assimilation.Quality control allows us to effectively eliminate or absorb these outliers to produce better analysis fields.In particular,variational quality control(VarQC) can process gray zone outliers and is thus broadly used in variational data assimilation systems.In this study,governing equations are derived for two VarQC algorithms that utilize different contaminated Gaussian distributions(CGDs): Gaussian plus flat distribution and Huber norm distribution.As such,these VarQC algorithms can handle outliers that have non-Gaussian innovations.Then,these VarQC algorithms are implemented in the Global/Regional Assimilation and PrEdiction System(GRAPES) model-level three-dimensional variational data assimilation(m3 DVAR) system.Tests using artificial observations indicate that the VarQC method using the Huber distribution has stronger robustness for including outliers to improve posterior analysis than the VarQC method using the Gaussian plus flat distribution.Furthermore,real observation experiments show that the distribution of observation analysis weights conform well with theory,indicating that the application of VarQC is effective in the GRAPES m3 DVAR system.Subsequent case study and longperiod data assimilation experiments show that the spatial distribution and amplitude of the observation analysis weights are related to the analysis increments of the mass field(geopotential height and temperature).Compared to the control experiment,VarQC experiments have noticeably better posterior mass fields.Finally,the VarQC method using the Huber distribution is superior to the VarQC method using the Gaussian plus flat distribution,especially at the middle and lower levels.
文摘WHO strategy on traditional medicine is based on security and quality of phytomedicine. Commonly adulterated affecting mostly metabolic and sexual dysfunction drugs. Control quality of those phytomedicines requires development of strategy and techniques applicable to them. Among the techniques, Reverse Phase Liquid Chromatography is the most used and has been developed in these studies to assess a protocol to characterize Gardenia aqualla leaves extract. The method consists in determining chromatographic conditions using organic and pH gradient models based on water and acetonitrile combined with pH modifiers made up of formic acid (AF) and ammonium hydroxide (NH<sub>3</sub>). Results show that extracts contain mainly acidic compounds quickly eluted by NH<sub>3</sub> and more retained by AF. Optimal pH range for separation is 3 - 7 corresponding to 1.59 mM of NH<sub>3</sub> and 6.55 mM of AF. In these conditions, elution of many polar compounds could be effective using a C18 based-deactivated column in a short period of time.
文摘Background:Good adherence to post-operative exercise is crucial for long-term exercise intervention programs aimed at improving compliance,motivation for functional exercise,and quality of life among breast cancer patients.This study aims to evaluate the application effect of quality control circles on postoperative functional exercise compliance in breast neoplasm patients.Methods:A comprehensive search was conducted in CNKI,Wanfang,VIP,CBM,PubMed,Cochrane Library,Web of Science and CINAHL databases from their establishment to May 06,2023.Manual search and backtracking of relevant literature were also conducted.The search terms included a combination of subject terms and free words.Meta-analysis was performed using RevMan 5.4 software on eligible literature.Results:Initially,517 papers were retrieved,and after removing duplicates 238 papers using NoteExpress software,279 titles and abstracts were reviewed.Subsequently,225 non-compliant papers were excluded,leaving 54 full texts to be read.After excluding 38 non-compliant papers,16 eligible papers were included for Meta-analysis.These papers comprised a total of 1,342 patients(679 in the test group and 663 in the control group).The heterogeneity test using a fixed effects model showed P=0.22 and I2=21%.The Meta-analysis results demonstrated that the implementation of quality control circles alongside usual care significantly improved compliance with postoperative functional exercise in breast cancer patients(odds ratio=6.68,95%confidence interval(4.97,8.98),P<0.00001).Conclusion:Quality control circles activities can effectively enhance compliance with post-operative functional exercise among breast cancer patients,aiding in the recovery of affected limb function,improvement of self-care ability,and early reintegration into society and normal life,thereby enhancing quality of life.It is important to continually accumulate experience in applying relevant quality control circles activities in clinical work and promptly enhance the level of care accordingly,as the functional exercise of breast cancer patients after surgery involves a long-term and gradual improvement process.
文摘Objective: To carry out empirical research on the role of project-achieving quality control circle (QCC) in constructing a new model of contactless medical service for outpatients. Methods: A QCC, consisting of information office members from a grade A tertiary hospital in Wenzhou, was established to conduct a research project with the theme “Constructing a new model of contactless medical service based on outpatients’ experience.” According to the ten steps and PDCA cycle, an analysis was carried out before and after the QCC activities, focusing on improving pre-consultation services, providing steward-like services, and facilitating post-consultation management. Results: After the QCC activities, the mobile appointment rate, missed appointment rate, the proportion of smart check-ins, and the average check-in time were 55.68%, 4.02%, 39.75%, and 8.24 ± 3.66 min, respectively;in contrast, before the activities, they were 32.00%, 7.88%, 0.00%, and 14.96 ± 4.98 min, respectively;the difference between the two groups was statistically significant (χ2 = 3480.112, 4994.496;Fisher’s exact probability = 963788.570;t = 5.323, P < 0.001). Many experts have also visited the hospital to learn about this system, thus rendering social and economic benefits. Conclusion: Project-achieving QCC activities are suitable for complex situations, such as constructing a new model of contactless medical service, and can significantly improve outpatient service quality, enhance patients’ experience, and improve the abilities of circle members.
文摘In view of social development,the demand for water conservancy engineering applications continues to increase.The number and scale of water conservancy projects in China have been in a state of continuous expansion in recent years.As a result,how to achieve efficient testing and effective control of the quality of water conservancy projects has always been a topic of discussion in the field of water conservancy engineering in our country.This paper summarizes the application of non-destructive testing technology in the quality testing and control of water conservancy projects.On the basis of explaining the connotation and application advantages of non-destructive testing technology,the non-destructive testing application strategies for concrete strength,steel corrosion and shallow cracks in water conservancy projects were studied.
文摘Objective:To analyze the effect of quality control circle on the central sterile supply department(CSSD).Methods:The control group and the observation group each consisted of 180 instruments received by the sterilization supply center from January to March 2023 and 11 CSSD staff.The control group underwent routine management while quality control circle was implemented in the observation group.The quality of work,disinfection and sterilization qualification rates,disinfection and sterilization of various instruments,cleaning indicators,and management satisfaction of both groups were compared.Results:The observation group scored higher in terms of work quality,the qualification rate of disinfection and sterilization in each link,the disinfection and sterilization of instruments,and cleaning indicators compared to the control group.Besides,the management satisfaction of the observation group was higher than that of the control group(P<0.05).Conclusion:A quality control circle ensures the quality of work,improves the cleaning,disinfection,and sterilization of instruments of the CSSD,and improves the management satisfaction of the CSSD staff.