Health Related Quality of Life and Mental Health in ICU Survivors: Post-Intensive Care Syndrome Follow-Up and Correlations between the 36-Item Short Form Health Survey (SF-36) and the General Health Questionnaire (GHQ-28)

We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.

SF-36量表和EORTC QLQ-LC43量表在肺癌患者生活质量测定中的应用效果

目的 比较健康调查简表(the MOS item short from health survey,SF-36)和欧洲癌症研究和治疗组织肿瘤肺癌患者生存质量量表(the European Organization for Research and Treatment of Cancer Quality of Life Core 30 Questionnaire,EORTC QLQ-LC43)在肺癌患者生活质量测定中的应用效果。方法 选取2020年9月—2022年6月158例肺癌患者作为研究对象,分别采用SF-36量表和EORTC QLQ-LC43量表调查受试对象的生活质量,采用Pearson线性相关性分析比较两种量表不同维度评分之间的相关性,以Karnofsky评分(KPS评分)功能状态评分作为效标,比较两种生存质量量表的相关性及效度。结果 SF-36量表总克朗巴赫系数为0.766,分量表克朗巴赫系数为0.493~0.849。SF-36量表的躯体功能、躯体角色、躯体疼痛、情感职能、社会活动、一般健康等6个分量表分别与EORTC QLQ-LC43量表的躯体功能、角色功能、疼痛、情绪功能、社会功能、整体生活质量的6个分量表对应,其相关系数为0.784~0.842,相关性差异有统计学意义(P<0.001)。上述对应的分量表具有中等程度的一致性(Kappa值> 0.4)。不同临床分期分组中,肺癌患者SF-36各个维度得分与肿瘤分期显著相关,肿瘤分期越晚,生存质量得分越低(P<0.001)。肺癌患者SF-36各个维度得分与患者的体力状态得分显著相关,体力状态越差,生存质量得分越低(P <0.001)。结论 与EORTC QLQ-LC43量表相比,SF-36量表在评价肺癌患者生活质量方面具有较高的一致性和区分能力,可以作为EORTC QLQ-LC43量表的替代。

SF-36量表评估中国中部地区脑萎缩人群的效果

目的探索脑萎缩影像学改变与SF-36量表之间的关联,探讨SF-36量表应用于脑萎缩患者的价值及其测量脑萎缩患者生命质量的信度和效度,评估SF-36量表评分对脑萎缩的诊断效能。方法随机选取263名居民进行磁共振平扫检查,并利用SF-36量表进行生活质量评测,采用克隆巴赫系数(Cronbach'sα)、ROC曲线分析、Kappa检验分析SF-36量表的信度和诊断效能。单因素分析采用t检验,多因素分析采用Logistic回归分析来筛选生命质量相关因素。结果基于影像学金标准诊断的脑萎缩阳性组和脑萎缩阴性组在年龄、性别的差异具有统计学意义(P<0.05),BMI的构成比无统计学意义(P>0.05);脑萎缩患者SF-36量表中除SF、RE外,其余6各维度和PCS和MCS较中国常模数值均存在显著功能缺陷(P<0.05);SF-36量表总分及8个维度的Cronbach'sα系数均高于0.7,RP、BP、SF、RE 4个维度出现天花板效应,RP、RE这两个维度出现地板效应;Logistic回归分析显示,在未矫正其他变量时,SF-36总分和PCS得分与患脑萎缩的风险显著负相关51~60岁患者和女性患者患脑萎缩的风险显著上升;在调节性别、年龄、BMI等变量后,51~60岁患者和女性患者仍是患脑萎缩的独立危险因素。结论SF-36量表对脑萎缩患者生命质量的测量具有良好的信度和效度以及一定的区别能力,可以用于评价脑萎缩患者的生命质量,并为后续制定评价脑萎缩病情发展、治疗疗效的工具提供一定参考,但对于筛查和预测脑萎缩高风险人群效果不佳。

Quality of life and emotional change for middle -aged and elderly patients with diabetic retinopathy

AIM:To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions. METHODS:The present study included 108 diabetic retinopathy (DR) patients:54 with PDR and 54 with non-proliferative diabetic retinopathy (NPDR). Each healthy control group (n =54) sociodemographically matched to DR groups was established respectively. The quality of life, anxiety and depression symptoms were evaluated and analyzed on preoperative and postoperative month 1 using SF-36, DSQL and Hospital Anxiety and Depression Scale (HADS). · RESULTS:DR patients described impaired HRQL (Health Related Quality of life, SF -36) in 6 out of 8 subscales, including ‘Body Health’, ‘Body RoleFunction’,‘General Health’,‘Society Function’,‘Emotion Role Function’and‘Mental Health’. Compared with controls, DR patients (NPDR and PDR) suffered from statistically significantly impaired HRQL (SF-36 Summary score) (P【 0.05). By surgical intervention, the anxiety and depression score were significantly reduced, while the health and quality of life (SF-36 Summary scores and DSQL scores) was improved in patients with PDR (P 【0.05). CONCLUSION:DR patients were affected in mentation and quality of life. Surgery interventions can improve SF-36, DSQL, anxiety and depression in PDR patients.

Effects of hospital–community integrated transitional care on quality of life in patients with chronic obstructive pulmonary disease

Objective: To explore the effects of “hospital–community integrated transitional care” model on quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 117 inpatients with COPD from the Department of Respiratory Medicine in a tertiary general hospital in Nanjing were enrolled by convenience sampling from January to December in 2016 and then were divided into intervention group (n = 60) and control group (n = 57) by random number table. Patients in the intervention group accepted both routine care and hospital– community integrated transitional care for 3 months after discharge. Assessment of quality of life by telephone follow-up or interview within a week before discharge and 1, 3, and 6 months after discharge was evaluated using the Short Form-36 (SF-36) health survey questionnaire. Results: For a total score of quality of life, there was a significant difference between the two groups (P < 0.05): 1, 3, and 6 months after discharge. In addition, for each dimension score of quality of life, there were no significant differences (P > 0.05) except vitality dimension, 1 month after discharge, and there were significant differences in all dimensions, 3 and 6 months after discharge (P < 0.05) Conclusions: Hospital–community integrated transitional care model can improve the quality of life of patients with COPD.

Science Letters:Crossover randomized controlled trial of the electronic version of the Chinese SF-36

Objectives:to verify the feasibility and reliability of the electronic version of Chinese SF-36 based on the Quality-of-Life-Recorder. Design: A crossover randomized controlled trial, comparing a paper-based and an electronic version of the Chinese SF-36, was conducted. According to generated random numbers, interviewees were asked to fill out either the electronic version or the paper version first. The second version was filled in after a pause of at least 10 min. Settings and participants: One group of 100 medical students at the School of Medicine of Zhejiang University and the other group of 50 outpatients at a clinic for general practice in Hangzhou City (China) were eventually recruited in this study. Results: The acceptance of the electronic version was good (60% of medical students and 84% of outpatients preferred the electronic version). At the level of eight-scale scores, the mean-difference for each scale (except for general health) between the two versions was less than 5%. At the level of 36 questions, the percentage of "exact agreement" ranged within 64%～99%; the percentage of "global agreement" ranged within 72%～99%; 77% of the kappa coefficients demonstrated "good/excellent agreement" and 23% of the kappa coefficients demonstrated "medium agreement". Conclusion: This study, for the first time, can provide empirical basis for the confirmation of the feasibility and reliability of the electronic version of the Chinese SF-36 and may provide an impulse towards widespread deployment of the Quality-of-Life-Recorder in Chinese populations.

Prevalence of Chronic Pain, Especially Headache, and Relationship with Health-Related Quality of Life in Middle-Aged Japanese Residents

The aim of this study was to evaluate the prevalence of chronic pain (CP) and the relationship between CP, especially headache adjusted for CP at other sites, and health-related quality of life (HRQoL) in middle-aged Japanese residents. We examined the prevalence of CP (defined as pain persisting for 3 months or more) and HRQoL (SF-36) in 1117 middle-aged residents of Japan. We assessed the eight dimensions of health status and the 3 component SF-36 summary score to evaluate HRQoL. The prevalence of CP was 15.3% among men and 15.1% among women. Multiple linear regression analysis demonstrated that lumbar pain (p β = -0.132), knee pain (p β = -0.115), foot pain (p = 0.042, β = -0.065), and age (p β = -0.154) were independently correlated with a lower physical component score (PCS). Older age (ppβ = -0.096), knee pain (p β = -0.109), upper limb pain (p β = -0.098), and lumbar pain (p = 0.022, β = -0.077) all showed a significant negative correlation with MCS. The presence of chronic headache (p = 0.011, β = -0.082) was the only factor significantly correlated with a lower role component score (RCS). We identified a negative correlation between chronic headache and RCS, unlike the relation between musculoskeletal pain and PCS or MCS, suggesting that RCS was an independently influenced by CP differently from PCS or MCS in Japanese residents.

The Relationship between Quality of Life with Demographic Variables of Elderly in Golestan Province-Iran

Quality of life subscales was influenced by different factors including age, gender, and financial status and more importantly by health, education, financial and marital status. The main goal of this study was relationship between (QOL) with demographic variables of elderly in Golestan province-Iran. This research was an analytical cross study that conducted on 193 individuals going to Jahandidegan geriatric charity institution of Golestan-Iran. The data were collected from questionnaire SF-36 for QOL the elderly indicators through interviews and observation and then analyzed using SPSS V.17 Software. Among QOL dimensions, only general health status showed a significant association with supporting organizations covering status (P = 0.01). The relationship between QOL with current employment status in both genders was observed.

Quality of Life (QOL) in Long-Term Survivors of Osteosarcoma

We conducted this study to analyze the quality of life using the SF-36 health questionnaire and the MSTS scores depending on surgical method and the primary site of occurrence. On the surgical method, the limb salvage had more excellent outcomes (60.9) than the amputation (46.3). The tumor prosthetic replacement had notably higher scores (62.5) than any other methods. For the correlation coefficients on the MSTS and SF-36, the Physical Function had the highest degree of correlation. Excellent functions of the extremities would lead to a good quality of life.

Health related quality of life of university students in Lebanon: Lifestyles behaviors and socio-demographic predictors

Measuring and monitoring health related quality of life (HRQoL) in youth are important for both researchers and decision makers. During the time that young people are at university, many will encounter a number of academic, as well as social, emotional and psychological difficulties. The aims of this study are to: 1) assess the health related quality of life of youths using SF-36 questionnaire and its factor determinants, and 2) provide an objective basis for a health promotion structure. Methods: This is a cross-sectional study in South Lebanon, in a population of 282 young university students attending a public university which is the largest and most widespread institution of higher education in Lebanon. Socioeconomic and lifestyle behaviors data were collected. Students’ HRQoL was measured using the SF-36 Health Survey. Results: The mean age of the respondents was 18.7 years (SD = 1.16), 80.1% were women, 64.5% were living in rural area. The proportion of current smokers was significantly greater among men than women (26.8% vs. 11.5%, p < 0.01). Water pipe was the main type of smoking. Education of the fathers had negatively influenced HRQoL. Younger age scored higher in Social Functioning and Role-Emotional;the area of residence had no influences on SF-36 scales scores. Females had poorer HRQoL than males especially in mental health scales. Smokers had low Vitality and Mental Health scores. Sedentary lifestyle was linked to a lower score of Physical Functioning (β = -5.16, 95% CI = -7.67 -2.65), and Vitality ( β= -5.85, 95% CI = -10.24 -1.45). The HRQoL of the students studying business and economics was higher than those studying health. Conclusion: Youths’ HRQoL is affected by socio-demographic and behavioral characteristics. Effective health-promoting actions, social support, and counseling services should be implemented in the campus and are a necessary step towards the main goal of improving the overall HRQoL of the university young students in Lebanon.

Assessment of Health-Related Quality of Life of Tuberculosis Patients in Fako Division, South-West Region of Cameroon

Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the top 10 causes of death worldwide. Despite the global impact of TB and treatment received, a gap persists between treatment and quality of life of the patients especially in resource limited countries. This study therefore evaluated the health related quality of life of TB patients and the different factors influencing their quality of life at the post intensive phase of their treatment in the Fako division of the South-West Region of Cameroon. Methods: A hospital based cross sectional study was carried out in 4 tuberculosis treatment centers, namely two regional (Buea and Limbe) and two district (Tiko and Muyuka) hospitals in Fako Division between June and July 2017. One hundred and sixty-seven TB patients were enrolled in the study and relevant information from them was gathered using the SF-36 questionnaire. Various aspects such as their perception of the disease, their socio-demographics and socio-economics conditions were evaluated. Results: Of the 167 participants enrolled in the study, 95 (56.9%) were male and 72 (43.1%) were female. One hundred and thirty-three (79.6%) of the 167 participants were affected by pulmonary tuberculosis and 34 (20.4%) by extra-pulmonary tuberculosis. Fifty-five (32.9%) were HIV positive and 90 (53.9%) had been receiving treatment for 4 - 6 months, 73 (43.7%) for 1 - 3 months and 4 (2.4%) for 7 - 9 months. The lowest and highest scores were recorded on the role limitation due to emotional problems scale (30.54 ± 35.36), and on the social functioning scale (47.68 ± 16.33) respectively. There was a significant difference (p = 0.021), between pulmonary and extra pulmonary tuberculosis (49.15 ± 16.08 vs. 41.91 ± 16.25) on the social functioning. Financial difficulty restraining drug collection affected the general health perception (p = 0.003), vitality (p = 0.007), emotional well-being (p < 0.001) and social functioning (p = 0.05) of the patients. Low income affected the vitality (p = 0.039), emotional well-being (p = 0.015), role limitations due to physical (p = 0.046) and emotional (p = 0.003) problems of the patients. Equally, the HIV status affected their vitality (p < 0.001) and emotional well-being (p = 0.011). Conclusion: The quality of life of the TB patients in the study area was generally poor. Counselling of diagnosed TB patients and provision of financial assistance through a social package can improve the acceptance of the disease during their treatment period to avoid default and relapse.

Influence of Metabolic Syndrome versus Musculoskeletal Disorders on Saudi Health-Related Quality of Life

Aim: This work aimed to study the influence of two chronic health conditions, metabolic syndrome (MetS) and musculoskeletal disorders (MSDs), on the health-related quality of life (HRQoL) of Saudis. Method: The Medical Outcomes Study Short Form-36 (SF-36) health status questionnaire was used to measure the HRQoL and compare the mean scores of the questionnaire subscales and physical and mental component summaries (PCS and MCS) of 33 patients with MetS, 18 patients with MSDs, and 30 apparently healthy (AH) subjects. Regression analysis was used to measure the prediction power of the study group, age and gender of the participants in estimating the HRQoL. Results: Results showed that the mean scores of the physical subscales, the PCS, the mental subscales and MCS were arranged in descending order from AH subjects, patients with MetS, to patients with MSDs. The mean scores difference among the 3 study groups were statistically significant with the only exception for the general mental health (GMH) subscale (P = 0.404). The study group and age accounted for 41.8% of the variability of PCS while the study group accounted for 19.6% of the variability in the MCS. The resulted equation to estimate the PCS score was as follows: PCS = 113.18 - 12.85 (Group: 0 for AH, 1 for MetS, and 2 for MSDs) - 0.67 age. On the other hand the resulted equation to estimate the MCS score was as follows: MCS = 76.203 - 10.426 (Group: 0 for AH, 1 for MetS, and 2 for MSDs). Conclusion: Patients with MetS and patients with MSDs had lower HRQoL than AH subjects. All the physical and mental dimensions of HRQoL are negatively influenced with MetS and with MSDs with the only exception for the GMH subscale. The physical and mental burden of MSDs is more dominant. The study group and age can be used to predict the PCS while the study group can be used to predict the MCS.

Effect of Music on Quality of Life in Stable Angina: A Randomized Controlled Trial

Introduction: Quality of life associated with coronary artery disease can be affected by number of factors. Even though standard treatment has improved survival of such patients, the quality of life may be less than ideal as the disease affects the physical, social, and emotional functioning of such individuals. Therefore improvement of the quality of life of the patients with coronary artery disease is vital. Though music has been identified having a potential benefit in improving quality of life for many years, researches conducted to recognize the effect of music on quality of life were sparse. Therefore the aim of this study was to determine the effect of frequent long term listening to Indian classical music on quality of life in chronic stable angina (SA) patients. Methodology: This single blind randomized clinical trial was conducted for one month. The intervention group of 30 patients listened to a music based on Indian classical system at home twice a day complementary to their regular treatment. The control group of 30 was only on their usual treatment. Both groups were assessed before and after the intervention for the quality of life by the Sinhala version of SF-36 questionnaire. Results: A statistically significant increase of scores for physical function by 16.17

Physical Activity Level and Adult Saudi Health Related Quality of Life

Purpose: Physical inactivity in Saudi Arabia is a growing challenge to public health. This study aimed to define the relationship between the physical activity level (PAL) and adult Saudi health-related quality of life (HRQoL). Methods: Participants of this study were 100 Saudi adult aged from 18 - 70 years. The 36-Item Short-Form Health Status Survey (SF-36) was used to measure the participant’s HRQoL. The SF-36 is comprised of 8 domains. The electronic version of the General Practice Physical Activity Questionnaire was used to categorize participants in terms of physical activity level into;inactive, moderately inactive, moderately active, and active. Descriptive and inferential statistical tests were used to treat the collected data. Results: Results showed that only 17% of the Saudi adults had active PAL. The PAL had significantly positive relationship with 4 domains of HRQoL including: physical functioning (P = 0.004), role limitations caused by physical health problems (P = 0.048), vitality (P = 0.009), and general health (P = 0.044). Results also confirmed that the younger the subject, the higher the PAL (P = 0.0001) and the better the HRQoL. This is true for all domains except the role limitations caused by emotional problems and emotional wellbeing. Conclusion: The poor physical activity level of adult Saudi negatively impacts their HRQoL.

On Practice of the Effect of Systematic Family Nursing Guidance on the Quality of Life of Elderly Patients with Implanted Cardiac Pacemaker

Objective: To inquire into the effect of systematic family nursing guidance on improving the Quality of Life for elderly patients with implanted cardiac pacemaker. Methods: 41 elderly patients in accordance with the corresponding requirements were studied after offering systematic family nursing guidance and surveyed through the questionnaires about the QOL (quality of life) respectively 1 month, 3 months and 6 months after leaving hospital. Results: Compared with that of 1 month and 3 months after the operation, the questionnaire scores for 6 months after the operation were found to have significant improvement, and the differences were statistically significant. Conclusion: Systematic family nursing guidance can effectively improve the QOL for elderly patients with implanted cardiac pacemaker, which makes them spend their old age in comfort and happiness.

四川省城乡居民SF-36评价参考值

目的 制定 36条目简明量表 ( SF- 36 )参考值用于国内生命质量评价。方法 采用美国的评分标准及中国评分标准分别对四川省 16 0 3名农村居民和 6 46名城市居民的生命质量进行评价 ,并与香港及美国常模比较。结果 中国评分标准与美国评分标准所得结果高度相关 ,8个领域的相关系数均在 0 .98以上 ,但两种评分标准所得结果的差异有显著性 ;四川省城乡居民 SF- 36评价结果与香港及美国常模比较 ,更接近香港评价值 ;不同年龄、性别及城乡人群之间的评分结果有显著性差异。结论 制定了四川省城乡不同性别及年龄居民的 SF- 36评价参考值 ,为在国内使用 SF-

生命质量评价量表SF-36中国量化标准研究

目的 为便于跨文化研究 ,采用模糊数学的原理对 SF- 36进行中国量化标准研究。方法 在某城市按年龄、性别和职业分层抽取 6 5 0人 ,对 SF- 36的 8个领域中的 6个备择答案超过 2个的领域进行量化值区间估计。共收回有效问卷 6 46份。结果 多数答案等级的区间估计值的模糊度小于 0 .5 ,仅第一领域“躯体活动功能”有 4个答案等级的区间估计模糊度大于 0 .5。采用中国评分标准后 ,SF- 36的 8个领域得分值的高低顺位更接近原量表假设。结论 本研究研制的量化标准更适合于中国人群。建议将第一领域“躯体活动功能”的 3个答案等级简化为“是”“否”

SF-36评价2型糖尿病患者生存质量的研究

目的 :探讨SF - 36在 2型糖尿病患者生存质量评价中的作用。方法 :采用简明健康调查问卷 (SF - 36 )和糖尿病人生存质量特异性量表 (DSQL)及相关因素调查表对 2 10名 2型糖尿病患者进行问卷调查。在SPSS支持下 ,进行分半信度、秩相关和逐步回归分析。结果 :SF - 36用于评价 2型糖尿病患者生存质量的分半信度为 0 9899。其与糖尿病生存质量特异性量表 (DSQL)具有一定程度的相关性。经逐步回归分析 ,应对倾向、主观支持、客观支持、饮食控制被选入回归方程。结论 :SF - 36与DSQL配合使用可兼顾普适性与特异性 ,综合评价患者生存质量。

SF-36量表用于肝癌患者生活质量测定的效果评价

目的评价SF-36用于肝癌患者生活质量测定的效果。方法随机抽取105例肝癌患者用SF-36量表进行纵向的三次测定,计算量表的信度、效度和反应度。结果量表的结构与概念构思基本相符,提取的6个主成分代表了量表的各个领域;8 个领域的重测信度和内部一致性系数分别为:躯体功能0.76、0.84,躯体角色0.72、0.89,身体疼痛0.87、0.79,一般健康状况0.62、0.48,生命力0.63、0.57,社会功能0.65、0.40,情绪角色0.77、0.83,心理健康0.69、0.11;量表能敏感地反应治疗前后生命质量的变化。结论SF-36量表用于肝癌患者生命质量测定具有较好的信度、效度和反应度,因而有一定的实用价值。

SF-36评价中风患者生命质量的信度和效度

目的 评价SF 36生命质量量表在中风患者中的信度和效度。方法 效度评价采用结构效度和判别效度。采用ADL、IADL、闲暇活动、社会支持、健康预测对SF 36的 8个领域通过回归分析进行结构效度评价。采用神经功能缺损程度评价量表MESSS对SF 36进行判别效度的评价。信度采用重测信度法、内部一致性分析 (Cronbach’α系数 )。用自填法结合个人访谈法 ,由 15 0例中风患者自己做出健康评价。结果 整个测量的重测相关系数均大于 0 .6 (各领域P <0 .0 1)。内部一致性Cronbach’α系数除活力和精神健康两个领域为 0 .7～ 0 .8以外 ,其他 6个领域的内部一致性均很好 (α >0 .8)。在结构效度评价中 ,回归分析的结果与事先的假设具有相当的一致性。SF 36的 8个领域除疼痛领域以外 ,不同的神经功能缺损程度间均有显著差异 (P <0 .0 5 )。结论 采用自填法结合个人访谈 ,使用SF 36评价中风患者的生命质量是有效的。