A survey on agents, causality and intelligence is presented and an equilibrium-based computing paradigm of quantum agents and quantum intelligence (QAQI) is proposed. In the survey, Aristotle’s causality principle an...A survey on agents, causality and intelligence is presented and an equilibrium-based computing paradigm of quantum agents and quantum intelligence (QAQI) is proposed. In the survey, Aristotle’s causality principle and its historical extensions by David Hume, Bertrand Russell, Lotfi Zadeh, Donald Rubin, Judea Pearl, Niels Bohr, Albert Einstein, David Bohm, and the causal set initiative are reviewed;bipolar dynamic logic (BDL) is introduced as a causal logic for bipolar inductive and deductive reasoning;bipolar quantum linear algebra (BQLA) is introdused as a causal algebra for quantum agent interaction and formation. Despite the widely held view that causality is undefinable with regularity, it is shown that equilibrium-based bipolar causality is logically definable using BDL and BQLA for causal inference in physical, social, biological, mental, and philosophical terms. This finding leads to the paradigm of QAQI where agents are modeled as quantum enssembles;intelligence is revealed as quantum intelligence. It is shown that the enssemble formation, mutation and interaction of agents can be described as direct or indirect results of quantum causality. Some fundamental laws of causation are presented for quantum agent entanglement and quantum intelligence. Applicability is illustrated;major challenges are identified in equilibriumbased causal inference and quantum data mining.展开更多
The present pharmacochemical and modelling work focused on a benzimidazolyl-chalcone series. These previously synthesized compounds were evaluated in vitro for their anticancer activities against a panel of seven huma...The present pharmacochemical and modelling work focused on a benzimidazolyl-chalcone series. These previously synthesized compounds were evaluated in vitro for their anticancer activities against a panel of seven human cancer cell lines and normal fibroblasts. Among the new benzimidazole-supported chalcones, nine (9) compounds (compounds<strong> 1 - 4, 6 - 8 </strong>and compounds <strong>10</strong> and <strong>11</strong>) showed promising anticancer activities with IC<sub>50</sub>s ranging from 0.83 to 2.58 μM. Compounds <strong>2 </strong>and <strong>6</strong> with IC<sub>50</sub>s of 0.83 and 0.86 μM, respectively, were shown to be potent inhibitors of HCT-116 colon cancer cell proliferation. It was therefore necessary, for a development of this new series of chalcones, to establish through a QSAR study, their quantum descriptors according to the DFT calculation method and following the B3LYP/6-31+G (d,p) theory. These descriptive and predictive studies focused on the colon HCT 116 cell line which was found to be more sensitive to the anticancer action of our benzimidazolyl-retrochalcones. QSAR study showed that the electronic energy (E<sub>elec</sub>), lipophilicity (log<em>P</em>), chemical softness (<em>S</em>) and chemical hardness (<em>η</em>) of benzimidazolyl-retrochalcones play an important role in inhibiting cancer cell proliferation.展开更多
In this paper,a systematic study about the fluorescence spectrum characteristics of fluorescent whitening agent VBL in solution with the different effects,including the pH and solvent,was conducted.The fluorescence qu...In this paper,a systematic study about the fluorescence spectrum characteristics of fluorescent whitening agent VBL in solution with the different effects,including the pH and solvent,was conducted.The fluorescence quantum yields in 25 different solvents were measured by the reference of quinine sulfate.According to these a new fluorescence determinations of the VBL in paper was built.The linear regression equation of the method is IF = 0.82 + 6.18 ×107c(mol/L) with a correlation coefficient(r) of 0.9992.The linear range of the method is from 0 to 2.85×10-6g/mL and the detection limit is 9.59×10-9g/mL.展开更多
文摘A survey on agents, causality and intelligence is presented and an equilibrium-based computing paradigm of quantum agents and quantum intelligence (QAQI) is proposed. In the survey, Aristotle’s causality principle and its historical extensions by David Hume, Bertrand Russell, Lotfi Zadeh, Donald Rubin, Judea Pearl, Niels Bohr, Albert Einstein, David Bohm, and the causal set initiative are reviewed;bipolar dynamic logic (BDL) is introduced as a causal logic for bipolar inductive and deductive reasoning;bipolar quantum linear algebra (BQLA) is introdused as a causal algebra for quantum agent interaction and formation. Despite the widely held view that causality is undefinable with regularity, it is shown that equilibrium-based bipolar causality is logically definable using BDL and BQLA for causal inference in physical, social, biological, mental, and philosophical terms. This finding leads to the paradigm of QAQI where agents are modeled as quantum enssembles;intelligence is revealed as quantum intelligence. It is shown that the enssemble formation, mutation and interaction of agents can be described as direct or indirect results of quantum causality. Some fundamental laws of causation are presented for quantum agent entanglement and quantum intelligence. Applicability is illustrated;major challenges are identified in equilibriumbased causal inference and quantum data mining.
文摘The present pharmacochemical and modelling work focused on a benzimidazolyl-chalcone series. These previously synthesized compounds were evaluated in vitro for their anticancer activities against a panel of seven human cancer cell lines and normal fibroblasts. Among the new benzimidazole-supported chalcones, nine (9) compounds (compounds<strong> 1 - 4, 6 - 8 </strong>and compounds <strong>10</strong> and <strong>11</strong>) showed promising anticancer activities with IC<sub>50</sub>s ranging from 0.83 to 2.58 μM. Compounds <strong>2 </strong>and <strong>6</strong> with IC<sub>50</sub>s of 0.83 and 0.86 μM, respectively, were shown to be potent inhibitors of HCT-116 colon cancer cell proliferation. It was therefore necessary, for a development of this new series of chalcones, to establish through a QSAR study, their quantum descriptors according to the DFT calculation method and following the B3LYP/6-31+G (d,p) theory. These descriptive and predictive studies focused on the colon HCT 116 cell line which was found to be more sensitive to the anticancer action of our benzimidazolyl-retrochalcones. QSAR study showed that the electronic energy (E<sub>elec</sub>), lipophilicity (log<em>P</em>), chemical softness (<em>S</em>) and chemical hardness (<em>η</em>) of benzimidazolyl-retrochalcones play an important role in inhibiting cancer cell proliferation.
文摘In this paper,a systematic study about the fluorescence spectrum characteristics of fluorescent whitening agent VBL in solution with the different effects,including the pH and solvent,was conducted.The fluorescence quantum yields in 25 different solvents were measured by the reference of quinine sulfate.According to these a new fluorescence determinations of the VBL in paper was built.The linear regression equation of the method is IF = 0.82 + 6.18 ×107c(mol/L) with a correlation coefficient(r) of 0.9992.The linear range of the method is from 0 to 2.85×10-6g/mL and the detection limit is 9.59×10-9g/mL.
