Beloved is one of Toni Morrison's finest fiction,whose literary writing have a lot in common with the process of piecing quilts.Quilting,a traditional art of ritual for black women to preserve history and culture,...Beloved is one of Toni Morrison's finest fiction,whose literary writing have a lot in common with the process of piecing quilts.Quilting,a traditional art of ritual for black women to preserve history and culture,provides a holistic way to interpret black feminist theme in black women's novels.Meanwhile,based on the theory of black feminism,which is characterized by principles of identity,sisterhood and wholeness,quilting in Beloved will be analyzed in a new perspective.展开更多
Alice Walker's "Everyday Use" is a story about the use and reuse of the concept of heritage.Through analyzing the symbols of quilts and the churn,the author is in an attempt to expore the heritage passed...Alice Walker's "Everyday Use" is a story about the use and reuse of the concept of heritage.Through analyzing the symbols of quilts and the churn,the author is in an attempt to expore the heritage passed down from generations.展开更多
As an excellent writer in American ethnic literature,Alice Walker devoted full attention to African Americans and their culture.One of her famous stories Everyday Use is a good point,which is worth studying.From the h...As an excellent writer in American ethnic literature,Alice Walker devoted full attention to African Americans and their culture.One of her famous stories Everyday Use is a good point,which is worth studying.From the house,the quilt to the name,Al-ice Walker employed various symbols to show the theme of cultural heritage and identity.It is of significance to analyze and ex-plore the use of symbolism in the text so as to deepen the understanding of the theme.展开更多
In 1937, P. Dirac proposed the Large Number Hypothesis and Hypothesis of Variable Gravitational Constant [1], and later added notion of Continuous Creation of Matter in the World [2]. Developed Hypersphere World-Unive...In 1937, P. Dirac proposed the Large Number Hypothesis and Hypothesis of Variable Gravitational Constant [1], and later added notion of Continuous Creation of Matter in the World [2]. Developed Hypersphere World-Universe Model (WUM) follows these ideas, albeit introducing different mechanism of Matter creation. Most direct observational evidence of validity of WUM are: 1) Microwave Background Radiation and Intergalactic Plasma speak in favor of existence of Medium;2) Laniakea Supercluster with binding mass ~10<sup>17</sup>M<sub>⊙</sub> is home to Milky Way (MW) galaxy and ~10<sup>5</sup> other nearby galaxies, which did not start their movement from Initial Singularity (see Figure 1);3) MW is gravitationally bounded with Virgo Supercluster (VSC) and has Orbital Angular Momentum calculated based on distance of 65 Mly from VSC and orbital speed of ~400 km·s<sup>-1</sup>, which far exceeds rotational angular momentum of MW;4) Mass-to-light ratio of VSC is ~300 times larger than that of Solar ratio. Similar ratios are obtained for other superclusters (see Figure 2). These ratios are main arguments in favor of the presence of tremendous amounts of Dark Matter (DM) in the World. JWST discoveries confirm the most important predictions of WUM in 2018: 1) Absolute Age of World is 14.22 Gyr;2) Dark Epoch (spanning for Laniakea Supercluster (LSC) from the Beginning of World for 0.45 Gyr) when only DM Macroobjects (MOs) form and evolve;3) Luminous Epoch (ever since, 13.77 Gyr for LSC) when Luminous MOs (superclusters, galaxies, extrasolar systems, etc.) emerge;4) Transition from Dark Epoch to Luminous Epoch is due to Explosive Rotational Fission of Overspinning (surface speed at equator exceeding escape velocity) DM Supercluster’s Cores and self-annihilation of DM Particles (DMPs);5) MOs of World form from top (Superclusters) down to Galaxies and Extrasolar systems in parallel around different Cores made up of different DMPs;6) 3D Finite Boundless World presents a Patchwork Quilt of different Luminous Superclusters, which emerged in different places of World at different Cosmological times.展开更多
The Xiaolan brand magnetic quilt made by the Zhejiang Tiantai Bedding and Clothing Factory is a new product. It is made of metal, hollow cotton and magnetic materials containing ammonium, iron and boron. The quilt is ...The Xiaolan brand magnetic quilt made by the Zhejiang Tiantai Bedding and Clothing Factory is a new product. It is made of metal, hollow cotton and magnetic materials containing ammonium, iron and boron. The quilt is extra light and thin, extremely warm and easy to wash. It is good for those suffering from nervous pain, back or leg pain, arthritis, shoulder pain, stomach ache.展开更多
Objective:Accurate prognosis prediction is critical for individualized-therapy making of gastric cancer patients.We aimed to develop and test 6-month,1-,2-,3-,5-,and 10-year overall survival(OS)and cancer-specific sur...Objective:Accurate prognosis prediction is critical for individualized-therapy making of gastric cancer patients.We aimed to develop and test 6-month,1-,2-,3-,5-,and 10-year overall survival(OS)and cancer-specific survival(CSS)prediction models for gastric cancer patients following gastrectomy.Methods:We derived and tested Survival Quilts,a machine learning-based model,to develop 6-month,1-,2-,3-,5-,and 10-year OS and CSS prediction models.Gastrectomy patients in the development set(n=20,583)and the internal validation set(n=5,106)were recruited from the Surveillance,Epidemiology,and End Re-sults(SEER)database,while those in the external validation set(n=6,352)were recruited from the China National Cancer Center Gastric Cancer(NCCGC)database.Furthermore,we selected gastrectomy patients with-out neoadjuvant therapy as a subgroup to train and test the prognostic models in order to keep the accuracy of tumor-node-metastasis(TNM)stage.Prognostic performances of these OS and CSS models were assessed using the Concordance Index(C-index)and area under the curve(AUC)values.Results:The machine learning model had a consistently high accuracy in predicting 6-month,1-,2-,3-,5-,and 10-year OS in the SEER development set(C-index=0.861,0.832,0.789,0.766,0.740,and 0.709;AUC=0.784,0.828,0.840,0.849,0.869,and 0.902,respectively),SEER validation set(C-index=0.782,0.739,0.712,0.698,0.681,and 0.660;AUC=0.751,0.772,0.767,0.762,0.766,and 0.787,respectively),and NCCGC set(C-index=0.691,0.756,0.751,0.737,0.722,and 0.701;AUC=0.769,0.788,0.790,0.790,0.787,and 0.788,respectively).The model was able to predict 6-month,1-,2-,3-,5-,and 10-year CSS in the SEER development set(C-index=0.879,0.858,0.820,0.802,0.784,and 0.774;AUC=0.756,0.827,0.852,0.863,0.874,and 0.884,respectively)and SEER validation set(C-index=0.790,0.763,0.741,0.729,0.718,and 0.708;AUC=0.706,0.758,0.767,0.766,0.766,and 0.764,respectively).In multivariate analysis,the high-risk group with risk score output by 5-year OS model was proved to be a strong survival predictor both in the SEER development set(hazard ratio[HR]=14.59,95%confidence interval[CI]:1.872-2.774,P<0.001),SEER validation set(HR=2.28,95%CI:13.089-16.293,P<0.001),and NCCGC set(HR=1.98,95%CI:1.617-2.437,P<0.001).We further explored the prognostic value of risk score resulted 5-year CSS model of gastrectomy patients,and found that high-risk group remained as an independent CSS factor in the SEER development set(HR=12.81,95%CI:11.568-14.194,P<0.001)and SEER validation set(HR=1.61,95%CI:1.338-1.935,P<0.001).Conclusion:Survival Quilts could allow accurate prediction of 6-month,1-,2-,3-,5-,and 10-year OS and CSS in gastric cancer patients following gastrectomy.展开更多
文摘Beloved is one of Toni Morrison's finest fiction,whose literary writing have a lot in common with the process of piecing quilts.Quilting,a traditional art of ritual for black women to preserve history and culture,provides a holistic way to interpret black feminist theme in black women's novels.Meanwhile,based on the theory of black feminism,which is characterized by principles of identity,sisterhood and wholeness,quilting in Beloved will be analyzed in a new perspective.
文摘Alice Walker's "Everyday Use" is a story about the use and reuse of the concept of heritage.Through analyzing the symbols of quilts and the churn,the author is in an attempt to expore the heritage passed down from generations.
文摘As an excellent writer in American ethnic literature,Alice Walker devoted full attention to African Americans and their culture.One of her famous stories Everyday Use is a good point,which is worth studying.From the house,the quilt to the name,Al-ice Walker employed various symbols to show the theme of cultural heritage and identity.It is of significance to analyze and ex-plore the use of symbolism in the text so as to deepen the understanding of the theme.
文摘In 1937, P. Dirac proposed the Large Number Hypothesis and Hypothesis of Variable Gravitational Constant [1], and later added notion of Continuous Creation of Matter in the World [2]. Developed Hypersphere World-Universe Model (WUM) follows these ideas, albeit introducing different mechanism of Matter creation. Most direct observational evidence of validity of WUM are: 1) Microwave Background Radiation and Intergalactic Plasma speak in favor of existence of Medium;2) Laniakea Supercluster with binding mass ~10<sup>17</sup>M<sub>⊙</sub> is home to Milky Way (MW) galaxy and ~10<sup>5</sup> other nearby galaxies, which did not start their movement from Initial Singularity (see Figure 1);3) MW is gravitationally bounded with Virgo Supercluster (VSC) and has Orbital Angular Momentum calculated based on distance of 65 Mly from VSC and orbital speed of ~400 km·s<sup>-1</sup>, which far exceeds rotational angular momentum of MW;4) Mass-to-light ratio of VSC is ~300 times larger than that of Solar ratio. Similar ratios are obtained for other superclusters (see Figure 2). These ratios are main arguments in favor of the presence of tremendous amounts of Dark Matter (DM) in the World. JWST discoveries confirm the most important predictions of WUM in 2018: 1) Absolute Age of World is 14.22 Gyr;2) Dark Epoch (spanning for Laniakea Supercluster (LSC) from the Beginning of World for 0.45 Gyr) when only DM Macroobjects (MOs) form and evolve;3) Luminous Epoch (ever since, 13.77 Gyr for LSC) when Luminous MOs (superclusters, galaxies, extrasolar systems, etc.) emerge;4) Transition from Dark Epoch to Luminous Epoch is due to Explosive Rotational Fission of Overspinning (surface speed at equator exceeding escape velocity) DM Supercluster’s Cores and self-annihilation of DM Particles (DMPs);5) MOs of World form from top (Superclusters) down to Galaxies and Extrasolar systems in parallel around different Cores made up of different DMPs;6) 3D Finite Boundless World presents a Patchwork Quilt of different Luminous Superclusters, which emerged in different places of World at different Cosmological times.
文摘The Xiaolan brand magnetic quilt made by the Zhejiang Tiantai Bedding and Clothing Factory is a new product. It is made of metal, hollow cotton and magnetic materials containing ammonium, iron and boron. The quilt is extra light and thin, extremely warm and easy to wash. It is good for those suffering from nervous pain, back or leg pain, arthritis, shoulder pain, stomach ache.
基金supported by grant from the National Key R&D Program of China(grant number:2017YFC0908300)the Fun-damental Research Funds for the Central Universities(grant number:3332023136).
文摘Objective:Accurate prognosis prediction is critical for individualized-therapy making of gastric cancer patients.We aimed to develop and test 6-month,1-,2-,3-,5-,and 10-year overall survival(OS)and cancer-specific survival(CSS)prediction models for gastric cancer patients following gastrectomy.Methods:We derived and tested Survival Quilts,a machine learning-based model,to develop 6-month,1-,2-,3-,5-,and 10-year OS and CSS prediction models.Gastrectomy patients in the development set(n=20,583)and the internal validation set(n=5,106)were recruited from the Surveillance,Epidemiology,and End Re-sults(SEER)database,while those in the external validation set(n=6,352)were recruited from the China National Cancer Center Gastric Cancer(NCCGC)database.Furthermore,we selected gastrectomy patients with-out neoadjuvant therapy as a subgroup to train and test the prognostic models in order to keep the accuracy of tumor-node-metastasis(TNM)stage.Prognostic performances of these OS and CSS models were assessed using the Concordance Index(C-index)and area under the curve(AUC)values.Results:The machine learning model had a consistently high accuracy in predicting 6-month,1-,2-,3-,5-,and 10-year OS in the SEER development set(C-index=0.861,0.832,0.789,0.766,0.740,and 0.709;AUC=0.784,0.828,0.840,0.849,0.869,and 0.902,respectively),SEER validation set(C-index=0.782,0.739,0.712,0.698,0.681,and 0.660;AUC=0.751,0.772,0.767,0.762,0.766,and 0.787,respectively),and NCCGC set(C-index=0.691,0.756,0.751,0.737,0.722,and 0.701;AUC=0.769,0.788,0.790,0.790,0.787,and 0.788,respectively).The model was able to predict 6-month,1-,2-,3-,5-,and 10-year CSS in the SEER development set(C-index=0.879,0.858,0.820,0.802,0.784,and 0.774;AUC=0.756,0.827,0.852,0.863,0.874,and 0.884,respectively)and SEER validation set(C-index=0.790,0.763,0.741,0.729,0.718,and 0.708;AUC=0.706,0.758,0.767,0.766,0.766,and 0.764,respectively).In multivariate analysis,the high-risk group with risk score output by 5-year OS model was proved to be a strong survival predictor both in the SEER development set(hazard ratio[HR]=14.59,95%confidence interval[CI]:1.872-2.774,P<0.001),SEER validation set(HR=2.28,95%CI:13.089-16.293,P<0.001),and NCCGC set(HR=1.98,95%CI:1.617-2.437,P<0.001).We further explored the prognostic value of risk score resulted 5-year CSS model of gastrectomy patients,and found that high-risk group remained as an independent CSS factor in the SEER development set(HR=12.81,95%CI:11.568-14.194,P<0.001)and SEER validation set(HR=1.61,95%CI:1.338-1.935,P<0.001).Conclusion:Survival Quilts could allow accurate prediction of 6-month,1-,2-,3-,5-,and 10-year OS and CSS in gastric cancer patients following gastrectomy.
