Non-invasive cardiac-pulmonary gating is proposed to improve the imaging resolution. It produces signals based on the cardiac-pulmonary motion of an animal in real-time. The system with the non-invasive gating consist...Non-invasive cardiac-pulmonary gating is proposed to improve the imaging resolution. It produces signals based on the cardiac-pulmonary motion of an animal in real-time. The system with the non-invasive gating consists of a digital signal processor (DSP), an electrocardiography (ECG) detection circuit and a thermoeouple circuit. An enhanced R wave detection algorithm based on zero crossing counts is used to adjust the low sample frequency associated with the respiratory rate of an animal. The thermocouple recognizes the respiration phase by sensing the temperature changes of the nasal airflow of an animal. The proposed gating can accurately generate the gating signal for freely breathing mice (weight of around 0.03 kg), and its respiratory signal is too weak to be detected. Apart from non-invasiveness, compared with other existing gating techniques, it occupies minimal space at lower cost. Actually, it can be used in micro-computed tomography (CT) and other systems needed to detect the cardiac-pulmonary motion. Several tests validate that the proposed cardiac-pulmonary gating can generate the gating signal as required. By using the gating technique, the image resolution is improved.展开更多
Electrocardiogram(ECG) can be used as a valid way for diagnosing heart disease.To fulfill ECG processing in wearable devices by reducing computation complexity and hardware cost,two kinds of adaptive filters are des...Electrocardiogram(ECG) can be used as a valid way for diagnosing heart disease.To fulfill ECG processing in wearable devices by reducing computation complexity and hardware cost,two kinds of adaptive filters are designed to perform QRS complex detection and motion artifacts removal,respectively.The proposed design achieves a sensitivity of 99.49% and a positive predictivity of 99.72%,tested under the MIT-BIH ECG database.The proposed design is synthesized under the SMIC 65-nm CMOS technology and verified by post-synthesis simulation.Experimental results show that the power consumption and area cost of this design are of 160 μW and 1.09×10^5 μm^2,respectively.展开更多
基金Supported by the National Basic Research Program of China ("973" Program) (2006CB705700)~~
文摘Non-invasive cardiac-pulmonary gating is proposed to improve the imaging resolution. It produces signals based on the cardiac-pulmonary motion of an animal in real-time. The system with the non-invasive gating consists of a digital signal processor (DSP), an electrocardiography (ECG) detection circuit and a thermoeouple circuit. An enhanced R wave detection algorithm based on zero crossing counts is used to adjust the low sample frequency associated with the respiratory rate of an animal. The thermocouple recognizes the respiration phase by sensing the temperature changes of the nasal airflow of an animal. The proposed gating can accurately generate the gating signal for freely breathing mice (weight of around 0.03 kg), and its respiratory signal is too weak to be detected. Apart from non-invasiveness, compared with other existing gating techniques, it occupies minimal space at lower cost. Actually, it can be used in micro-computed tomography (CT) and other systems needed to detect the cardiac-pulmonary motion. Several tests validate that the proposed cardiac-pulmonary gating can generate the gating signal as required. By using the gating technique, the image resolution is improved.
基金supported by the National Natural Science Foundation of China(Nos.61574040,61234002,61525401)
文摘Electrocardiogram(ECG) can be used as a valid way for diagnosing heart disease.To fulfill ECG processing in wearable devices by reducing computation complexity and hardware cost,two kinds of adaptive filters are designed to perform QRS complex detection and motion artifacts removal,respectively.The proposed design achieves a sensitivity of 99.49% and a positive predictivity of 99.72%,tested under the MIT-BIH ECG database.The proposed design is synthesized under the SMIC 65-nm CMOS technology and verified by post-synthesis simulation.Experimental results show that the power consumption and area cost of this design are of 160 μW and 1.09×10^5 μm^2,respectively.