Climate change is an alarming global challenge, particularly affecting the least developed countries (LDCs) including Liberia. These countries, located in regions prone to unpredictable temperature and precipitation c...Climate change is an alarming global challenge, particularly affecting the least developed countries (LDCs) including Liberia. These countries, located in regions prone to unpredictable temperature and precipitation changes, are facing significant challenges, particularly in climate-sensitive sectors such as mining and agriculture. LDCs need more resilience to adverse climate shocks but have limited capacity for adaptation compared to other developed and developing nations. This paper examines Liberia’s susceptibility to climate change as a least developed country, focusing on its exposure, sensitivity, and adaptive capacity. It provides an overview of LDCs and outlines the global distribution of carbon dioxide emissions. The paper also evaluates specific challenges that amplify Liberia’s vulnerability and constrain sustainable adaptation, providing insight into climate change’s existing and potential effects. The paper emphasizes the urgency of addressing climate impacts on Liberia and calls for concerted local and international efforts for effective and sustainable mitigation efforts. It provides recommendations for policy decisions and calls for further research on climate change mitigation and adaptation.展开更多
Baoshan Iron ＆ Steel Co.,Ltd., （referred to as Baosteel） in China first succeeded in developing the U-ing-O- ing-Expanding （UOE） longitudinal submerged arc welded pipes （SAWLs） offshore linepipe of a maximum th...Baoshan Iron ＆ Steel Co.,Ltd., （referred to as Baosteel） in China first succeeded in developing the U-ing-O- ing-Expanding （UOE） longitudinal submerged arc welded pipes （SAWLs） offshore linepipe of a maximum thickness/ outside diameter （T/D） 0.042 in 2011. Described in this paper is the research and development of the X70 UOE SAWL pipes by the company. The result shows that the said X70 linepipe has been in compliance with relevant requirements as specified in Specifications DNV-OS-F101 ,and has been successfully used in the South China Sea deepwater gas pipeline project.展开更多
There is a growing demand for customised,biocompatible,and sterilisable components in the medical busi-ness.3D Printing is a disruptive technology for healthcare and provides significant research and development avenu...There is a growing demand for customised,biocompatible,and sterilisable components in the medical busi-ness.3D Printing is a disruptive technology for healthcare and provides significant research and development avenues.Simple 3D printing service gives patients low-cost individualised prostheses,implants,and gadgets,en-abling surgeons to operate more effectively with customised equipment and models;and assisting medical device manufacturers in developing new and faster goods.3D printed tissue pieces can overcome various challenges and may eventually allow medication companies to streamline research and development.In the long run,it may also assist in lowering prices and making medicines more accessible and effective for everybody.There is a growing corpus of research on the advantages of employing 3D printed anatomic models in teaching and training.The capacity to 3D printing individual anatomical diseases for practical learning is one of the funda-mental contrasts between utilising 3D and regular anatomical models.3D printing is very appealing for producing patient-specific implants.This literature review-based paper explores the role of 3D printing and 3D bioprinting in healthcare.It briefs the need and progressive steps for implementing 3D printing in healthcare and presented various facilities and enablers of 3D printing for the healthcare sector.Finally,this paper identifies and discusses the significant applications of 3D printing for healthcare research and development.3D printing services can be deployed to easily construct complex geometries in plastic or metal with good precision.This results in improved prototypes,lower costs,and lower part processing times.They can now physically create with natural materials,previously unattainable with prior technologies.Every hospital should have 3D printers in the future,allowing new organs/parts to be developed in-house.展开更多
The paper addresses challenges on organization and funding of research and development (http://www.multitran.ru/c/m.exe?a=110&t=4200527_2_1&sc=0 R&D) in the agricultural sector. The necessity of modernizat...The paper addresses challenges on organization and funding of research and development (http://www.multitran.ru/c/m.exe?a=110&t=4200527_2_1&sc=0 R&D) in the agricultural sector. The necessity of modernization and reequipment of agricultural sector was validated, which is important sector in the economy of Uzbekistan. The paper covers issues on increasing investments in agricultural research, implementation of results of research work into the agriculture production, strengthening of innovative activities. Also, the possibility of nonstate budgetary financing of scientificresearch process in the agrarian sector was considered. Author’s view is given on the main directions of science that need to be supported as a foundation of further development of agricultural R&D and as a result the agricultural production.展开更多
Entrepreneurship corporate social responsibility is concerned with obligations that should be undertaken by an enterprise or ＂enterprise citizen＂ to the society including interrelationship between enterprise and som...Entrepreneurship corporate social responsibility is concerned with obligations that should be undertaken by an enterprise or ＂enterprise citizen＂ to the society including interrelationship between enterprise and some related interest dependents. And it is a sense of value, discipline and respect to the people, community and environment-related policies of the enterprise. Obviously, the core of the notion refers to a commitment of the enterprise in order to improve living standard of related interest counterparts. Nowadays, entrepreneurship corporate social responsibility has been not only an ethical call, but also an institutional constraint. The consensus is that in operation process an enterprise should take into account of its economic, social and ethical effects on consumers, staffs, shareholders, communities, local governments and environment and make a better prospect to them. Based on this point of view, by field work and questionnaire method, this paper discusses specifically the interaction between TNCs＇ R＆D activities and local development of the Pudong New Area, a China＇s largest special economic zone in Shanghai to explore dynamics of the TNCs＇ R＆D activities, growth of the local economy and their roles in promoting flexible innovation networks for sustainable futures. This involves： a. notion of the entrepreneurship corporate social responsibility; b. current state and trend of TNCs＇ R＆D activities; c. mode and linkage tightness between TNCs＇ R＆D activities and the local economy; d. main problems of the TNCs＇ R＆D activities in Pudong; e. the context of flexible innovation networks; and f. manner and ways in creation of flexible innovation networks.展开更多
Environmental technology (ET) refers to the processes and techniques for environmental prevention, reduction, recycling, reuse and rehabilitation. Since 1978, China has launched a series of R&D programs in promoti...Environmental technology (ET) refers to the processes and techniques for environmental prevention, reduction, recycling, reuse and rehabilitation. Since 1978, China has launched a series of R&D programs in promoting environmental science and technology development. Uneven spatial distribution and sectoral structure give us a profile of the present status of ET in China. Both opportunities and constraints are analyzed for the development of ET, and strategies for its future development are presented in this paper.展开更多
To stay globally competitive, manufacturing companies are increasingly under pressure to bring new products and applications to market, improve existing products, and discover new technologies to produce them at a low...To stay globally competitive, manufacturing companies are increasingly under pressure to bring new products and applications to market, improve existing products, and discover new technologies to produce them at a lower price. New technological findings can enable companies to overcome these challenges. In practice, technology development associated with a long time horizon is often given a lower priority compared with short-term focused product development thus being stronger restricted by everyday business. More and more companies separate their technology development department from product development to promote technological innovations. Due to this additional interface in the R＆D organization new problems arise, resulting in technologies not being implemented in products. The reasons for these problems amongst others concern wrong timing for the transfer or inadequate definition of responsibilities. In this paper of ongoing research, authors introduce a framework to design the transfer processes between technology development and product development. Although there are a number of options for designing the operative transfer, there is no regulatory framework specifying which configuration options are at this particular interface. The approach is to develop a model, which is able to design different company-specific transfer processes taking into account the object being transferred at this interface. Thus, for different objects to be transferred, different transfer processes are designed. The model＇s aim is to enable responsibility of the R＆D management to design their company-specific transfer processes to enable more technologies being implemented into products, thus giving the whole company the possibility to act more innovatively.展开更多
This review starts with a brief history of drug discovery & development, and the place of Asia in this worldwide effort discussed. The conditions and constraints of a successful translational R&D involving aca...This review starts with a brief history of drug discovery & development, and the place of Asia in this worldwide effort discussed. The conditions and constraints of a successful translational R&D involving academic basic research and clinical research are discussed and the Singapore model for pursuit of open R&D described. The importance of well-characterized, validated drug targets for the search for novel targeted anti-cancer agents is emphasized, as well as a structured, high quality translational R&D. Furthermore, the characteristics of an attractive preclinical development drug candidate are discussed laying the foundation of a successful preclinical development. The most frequent sources of failures are described and risk management at every stage is highly recommended. Organizational factors are also considered to play an important role. The factors to consider before starting a new drug discovery & development project are described, and an example is given of a successful clinical project that has had its roots in local universities and was carried through preclinical development into phase I clinical trials.展开更多
The evaluation system of R＆D project beforehand, in the course and afterwards embodies the principle and standard of the cycle economy, which can not only avoid the negative effects caused, by the utilization of the ...The evaluation system of R＆D project beforehand, in the course and afterwards embodies the principle and standard of the cycle economy, which can not only avoid the negative effects caused, by the utilization of the achievements of R＆D project in the industry but also point out the direction and criterion of R＆D activities for the enterprises, which also provides the ＂model＂ that can be used for reference for maintaining the durable competitiveness of the enterprises.展开更多
文摘Climate change is an alarming global challenge, particularly affecting the least developed countries (LDCs) including Liberia. These countries, located in regions prone to unpredictable temperature and precipitation changes, are facing significant challenges, particularly in climate-sensitive sectors such as mining and agriculture. LDCs need more resilience to adverse climate shocks but have limited capacity for adaptation compared to other developed and developing nations. This paper examines Liberia’s susceptibility to climate change as a least developed country, focusing on its exposure, sensitivity, and adaptive capacity. It provides an overview of LDCs and outlines the global distribution of carbon dioxide emissions. The paper also evaluates specific challenges that amplify Liberia’s vulnerability and constrain sustainable adaptation, providing insight into climate change’s existing and potential effects. The paper emphasizes the urgency of addressing climate impacts on Liberia and calls for concerted local and international efforts for effective and sustainable mitigation efforts. It provides recommendations for policy decisions and calls for further research on climate change mitigation and adaptation.
文摘Baoshan Iron ＆ Steel Co.,Ltd., （referred to as Baosteel） in China first succeeded in developing the U-ing-O- ing-Expanding （UOE） longitudinal submerged arc welded pipes （SAWLs） offshore linepipe of a maximum thickness/ outside diameter （T/D） 0.042 in 2011. Described in this paper is the research and development of the X70 UOE SAWL pipes by the company. The result shows that the said X70 linepipe has been in compliance with relevant requirements as specified in Specifications DNV-OS-F101 ,and has been successfully used in the South China Sea deepwater gas pipeline project.
文摘There is a growing demand for customised,biocompatible,and sterilisable components in the medical busi-ness.3D Printing is a disruptive technology for healthcare and provides significant research and development avenues.Simple 3D printing service gives patients low-cost individualised prostheses,implants,and gadgets,en-abling surgeons to operate more effectively with customised equipment and models;and assisting medical device manufacturers in developing new and faster goods.3D printed tissue pieces can overcome various challenges and may eventually allow medication companies to streamline research and development.In the long run,it may also assist in lowering prices and making medicines more accessible and effective for everybody.There is a growing corpus of research on the advantages of employing 3D printed anatomic models in teaching and training.The capacity to 3D printing individual anatomical diseases for practical learning is one of the funda-mental contrasts between utilising 3D and regular anatomical models.3D printing is very appealing for producing patient-specific implants.This literature review-based paper explores the role of 3D printing and 3D bioprinting in healthcare.It briefs the need and progressive steps for implementing 3D printing in healthcare and presented various facilities and enablers of 3D printing for the healthcare sector.Finally,this paper identifies and discusses the significant applications of 3D printing for healthcare research and development.3D printing services can be deployed to easily construct complex geometries in plastic or metal with good precision.This results in improved prototypes,lower costs,and lower part processing times.They can now physically create with natural materials,previously unattainable with prior technologies.Every hospital should have 3D printers in the future,allowing new organs/parts to be developed in-house.
文摘The paper addresses challenges on organization and funding of research and development (http://www.multitran.ru/c/m.exe?a=110&t=4200527_2_1&sc=0 R&D) in the agricultural sector. The necessity of modernization and reequipment of agricultural sector was validated, which is important sector in the economy of Uzbekistan. The paper covers issues on increasing investments in agricultural research, implementation of results of research work into the agriculture production, strengthening of innovative activities. Also, the possibility of nonstate budgetary financing of scientificresearch process in the agrarian sector was considered. Author’s view is given on the main directions of science that need to be supported as a foundation of further development of agricultural R&D and as a result the agricultural production.
文摘Entrepreneurship corporate social responsibility is concerned with obligations that should be undertaken by an enterprise or ＂enterprise citizen＂ to the society including interrelationship between enterprise and some related interest dependents. And it is a sense of value, discipline and respect to the people, community and environment-related policies of the enterprise. Obviously, the core of the notion refers to a commitment of the enterprise in order to improve living standard of related interest counterparts. Nowadays, entrepreneurship corporate social responsibility has been not only an ethical call, but also an institutional constraint. The consensus is that in operation process an enterprise should take into account of its economic, social and ethical effects on consumers, staffs, shareholders, communities, local governments and environment and make a better prospect to them. Based on this point of view, by field work and questionnaire method, this paper discusses specifically the interaction between TNCs＇ R＆D activities and local development of the Pudong New Area, a China＇s largest special economic zone in Shanghai to explore dynamics of the TNCs＇ R＆D activities, growth of the local economy and their roles in promoting flexible innovation networks for sustainable futures. This involves： a. notion of the entrepreneurship corporate social responsibility; b. current state and trend of TNCs＇ R＆D activities; c. mode and linkage tightness between TNCs＇ R＆D activities and the local economy; d. main problems of the TNCs＇ R＆D activities in Pudong; e. the context of flexible innovation networks; and f. manner and ways in creation of flexible innovation networks.
文摘Environmental technology (ET) refers to the processes and techniques for environmental prevention, reduction, recycling, reuse and rehabilitation. Since 1978, China has launched a series of R&D programs in promoting environmental science and technology development. Uneven spatial distribution and sectoral structure give us a profile of the present status of ET in China. Both opportunities and constraints are analyzed for the development of ET, and strategies for its future development are presented in this paper.
文摘To stay globally competitive, manufacturing companies are increasingly under pressure to bring new products and applications to market, improve existing products, and discover new technologies to produce them at a lower price. New technological findings can enable companies to overcome these challenges. In practice, technology development associated with a long time horizon is often given a lower priority compared with short-term focused product development thus being stronger restricted by everyday business. More and more companies separate their technology development department from product development to promote technological innovations. Due to this additional interface in the R＆D organization new problems arise, resulting in technologies not being implemented in products. The reasons for these problems amongst others concern wrong timing for the transfer or inadequate definition of responsibilities. In this paper of ongoing research, authors introduce a framework to design the transfer processes between technology development and product development. Although there are a number of options for designing the operative transfer, there is no regulatory framework specifying which configuration options are at this particular interface. The approach is to develop a model, which is able to design different company-specific transfer processes taking into account the object being transferred at this interface. Thus, for different objects to be transferred, different transfer processes are designed. The model＇s aim is to enable responsibility of the R＆D management to design their company-specific transfer processes to enable more technologies being implemented into products, thus giving the whole company the possibility to act more innovatively.
文摘This review starts with a brief history of drug discovery & development, and the place of Asia in this worldwide effort discussed. The conditions and constraints of a successful translational R&D involving academic basic research and clinical research are discussed and the Singapore model for pursuit of open R&D described. The importance of well-characterized, validated drug targets for the search for novel targeted anti-cancer agents is emphasized, as well as a structured, high quality translational R&D. Furthermore, the characteristics of an attractive preclinical development drug candidate are discussed laying the foundation of a successful preclinical development. The most frequent sources of failures are described and risk management at every stage is highly recommended. Organizational factors are also considered to play an important role. The factors to consider before starting a new drug discovery & development project are described, and an example is given of a successful clinical project that has had its roots in local universities and was carried through preclinical development into phase I clinical trials.
文摘The evaluation system of R＆D project beforehand, in the course and afterwards embodies the principle and standard of the cycle economy, which can not only avoid the negative effects caused, by the utilization of the achievements of R＆D project in the industry but also point out the direction and criterion of R＆D activities for the enterprises, which also provides the ＂model＂ that can be used for reference for maintaining the durable competitiveness of the enterprises.
