Visible light communication(VLC)has attracted much attention in the research of sixthgeneration(6G)systems.Furthermore,channel modeling is the foundation for designing efficient and robust VLC systems.In this paper,we...Visible light communication(VLC)has attracted much attention in the research of sixthgeneration(6G)systems.Furthermore,channel modeling is the foundation for designing efficient and robust VLC systems.In this paper,we present extensive VLC channel measurement campaigns in indoor environments,i.e.,an office and a corridor.Based on the measured data,the large-scale fading characteristics and multipath-related characteristics,including omnidirectional optical path loss(OPL),K-factor,power angular spectrum(PAS),angle spread(AS),and clustering characteristics,are analyzed and modeled through a statistical method.Based on the extracted statistics of the above-mentioned channel characteristics,we propose a statistical spatial channel model(SSCM)capable of modeling multipath in the spatial domain.Furthermore,the simulated statistics of the proposed model are compared with the measured statistics.For instance,in the office,the simulated path loss exponent(PLE)and the measured PLE are 1.96and 1.97,respectively.And,the simulated medians of AS and measured medians of AS are 25.94°and 24.84°,respectively.Generally,the fact that the simulated results fit well with measured results has demonstrated the accuracy of our SSCM.展开更多
In Beyond the Fifth Generation(B5G)heterogeneous edge networks,numerous users are multiplexed on a channel or served on the same frequency resource block,in which case the transmitter applies coding and the receiver u...In Beyond the Fifth Generation(B5G)heterogeneous edge networks,numerous users are multiplexed on a channel or served on the same frequency resource block,in which case the transmitter applies coding and the receiver uses interference cancellation.Unfortunately,uncoordinated radio resource allocation can reduce system throughput and lead to user inequity,for this reason,in this paper,channel allocation and power allocation problems are formulated to maximize the system sum rate and minimum user achievable rate.Since the construction model is non-convex and the response variables are high-dimensional,a distributed Deep Reinforcement Learning(DRL)framework called distributed Proximal Policy Optimization(PPO)is proposed to allocate or assign resources.Specifically,several simulated agents are trained in a heterogeneous environment to find robust behaviors that perform well in channel assignment and power allocation.Moreover,agents in the collection stage slow down,which hinders the learning of other agents.Therefore,a preemption strategy is further proposed in this paper to optimize the distributed PPO,form DP-PPO and successfully mitigate the straggler problem.The experimental results show that our mechanism named DP-PPO improves the performance over other DRL methods.展开更多
This study presents a layered generalization ensemble model for next generation radio mobiles,focusing on supervised channel estimation approaches.Channel estimation typically involves the insertion of pilot symbols w...This study presents a layered generalization ensemble model for next generation radio mobiles,focusing on supervised channel estimation approaches.Channel estimation typically involves the insertion of pilot symbols with a well-balanced rhythm and suitable layout.The model,called Stacked Generalization for Channel Estimation(SGCE),aims to enhance channel estimation performance by eliminating pilot insertion and improving throughput.The SGCE model incorporates six machine learning methods:random forest(RF),gradient boosting machine(GB),light gradient boosting machine(LGBM),support vector regression(SVR),extremely randomized tree(ERT),and extreme gradient boosting(XGB).By generating meta-data from five models(RF,GB,LGBM,SVR,and ERT),we ensure accurate channel coefficient predictions using the XGB model.To validate themodeling performance,we employ the leave-one-out cross-validation(LOOCV)approach,where each observation serves as the validation set while the remaining observations act as the training set.SGCE performances’results demonstrate higher mean andmedian accuracy compared to the separatedmodel.SGCE achieves an average accuracy of 98.4%,precision of 98.1%,and the highest F1-score of 98.5%,accurately predicting channel coefficients.Furthermore,our proposedmethod outperforms prior traditional and intelligent techniques in terms of throughput and bit error rate.SGCE’s superior performance highlights its efficacy in optimizing channel estimation.It can effectively predict channel coefficients and contribute to enhancing the overall efficiency of radio mobile systems.Through extensive experimentation and evaluation,we demonstrate that SGCE improved performance in channel estimation,surpassing previous techniques.Accordingly,SGCE’s capabilities have significant implications for optimizing channel estimation in modern communication systems.展开更多
The current resource allocation in 5G vehicular networks for mobile cloud communication faces several challenges,such as low user utilization,unbalanced resource allocation,and extended adaptive allocation time.We pro...The current resource allocation in 5G vehicular networks for mobile cloud communication faces several challenges,such as low user utilization,unbalanced resource allocation,and extended adaptive allocation time.We propose an adaptive allocation algorithm for mobile cloud communication resources in 5G vehicular networks to address these issues.This study analyzes the components of the 5G vehicular network architecture to determine the performance of different components.It is ascertained that the communication modes in 5G vehicular networks for mobile cloud communication include in-band and out-of-band modes.Furthermore,this study analyzes the single-hop and multi-hop modes in mobile cloud communication and calculates the resource transmission rate and bandwidth in different communication modes.The study also determines the scenario of one-way and two-way vehicle lane cloud communication network connectivity,calculates the probability of vehicle network connectivity under different mobile cloud communication radii,and determines the amount of cloud communication resources required by vehicles in different lane scenarios.Based on the communication status of users in 5G vehicular networks,this study calculates the bandwidth and transmission rate of the allocated channels using Shannon’s formula.It determines the adaptive allocation of cloud communication resources,introduces an objective function to obtain the optimal solution after allocation,and completes the adaptive allocation process.The experimental results demonstrate that,with the application of the proposed method,the maximum utilization of user communication resources reaches approximately 99%.The balance coefficient curve approaches 1,and the allocation time remains under 2 s.This indicates that the proposed method has higher adaptive allocation efficiency.展开更多
Due to the large amount of unused and unexplored spectrum resources, the so-called subTerahertz(sub-THz) frequency bands from 100 to 300 GHz are seen as promising bands for the next generation of wireless communicatio...Due to the large amount of unused and unexplored spectrum resources, the so-called subTerahertz(sub-THz) frequency bands from 100 to 300 GHz are seen as promising bands for the next generation of wireless communication systems. Channel modeling at sub-THz bands is essential for the design and deployment of future wireless communication systems. Channel measurement is a widely adopted method to obtain channel characteristics and establish mathematical channel models. Channel measurements depend on the design and construction of channel sounders. Thus, reliable channel sounding techniques and accurate channel measurements are required. In this paper, the requirements of an ideal channel sounder are discussed and the main channel sounding techniques are described for the subTHz frequency bands. The state-of-the-art sub-THz channel sounders reported in the literature and respective channel measurements are presented. Moreover, a vector network analyzer(VNA) based channel sounder, which supports frequency bands from 220 to330 GHz is presented and its performance capability and limitation are evaluated. This paper also discussed the challenge and future outlook of the sub-THz channel sounders and measurements.展开更多
In this paper,ambient IoT is used as a typical use case of massive connections for the sixth generation(6G)mobile communications where we derive the performance requirements to facilitate the evaluation of technical s...In this paper,ambient IoT is used as a typical use case of massive connections for the sixth generation(6G)mobile communications where we derive the performance requirements to facilitate the evaluation of technical solutions.A rather complete design of unsourced multiple access is proposed in which two key parts:a compressed sensing module for active user detection,and a sparse interleaver-division multiple access(SIDMA)module are simulated side by side on a same platform at balanced signal to noise ratio(SNR)operating points.With a proper combination of compressed sensing matrix,a convolutional encoder,receiver algorithms,the simulated performance results appear superior to the state-of-the-art benchmark,yet with relatively less complicated processing.展开更多
This paper investigates the Quality of Experience(QoE)oriented channel access anti-jamming problem in 5th Generation Mobile Communication(5G)ultra-dense networks.Firstly,considering that the 5G base station adopts bea...This paper investigates the Quality of Experience(QoE)oriented channel access anti-jamming problem in 5th Generation Mobile Communication(5G)ultra-dense networks.Firstly,considering that the 5G base station adopts beamforming technology,an anti-jamming model under Space Division Multiple Access(SDMA)conditions is proposed.Secondly,the confrontational relationship between users and the jammer is formulated as a Stackelberg game.Besides,to achieve global optimization,we design a local cooperation mechanism for users and formulate the cooperation and competition among users as a local altruistic game.By proving that the local altruistic game is an Exact Potential Game(EPG),we further prove the existence of pure strategy Nash Equilibrium(NE)among users and Stackelberg Equilibrium(SE)between users and jammer.Thirdly,to obtain the equilibrium solutions of the proposed games,we propose an anti-jamming channel selection algorithm and improve its convergence speed through heterogeneous learning parameters.The simulation results validate the convergence and effectiveness of the proposed algorithm.Compared with the throughput optimization scheme,our proposed scheme obtain a greater network satisfaction rate.Finally,we also analyze user fairness changes during the algorithm convergence process and get some interesting conclusions.展开更多
For a 5G wireless communication system,a convolutional deep neural network(CNN)is employed to synthesize a robust channel state estimator(CSE).The proposed CSE extracts channel information from transmit-and-receive pa...For a 5G wireless communication system,a convolutional deep neural network(CNN)is employed to synthesize a robust channel state estimator(CSE).The proposed CSE extracts channel information from transmit-and-receive pairs through offline training to estimate the channel state information.Also,it utilizes pilots to offer more helpful information about the communication channel.The proposedCNN-CSE performance is compared with previously published results for Bidirectional/long short-term memory(BiLSTM/LSTM)NNs-based CSEs.The CNN-CSE achieves outstanding performance using sufficient pilots only and loses its functionality at limited pilots compared with BiLSTM and LSTM-based estimators.Using three different loss function-based classification layers and the Adam optimization algorithm,a comparative study was conducted to assess the performance of the presented DNNs-based CSEs.The BiLSTM-CSE outperforms LSTM,CNN,conventional least squares(LS),and minimum mean square error(MMSE)CSEs.In addition,the computational and learning time complexities for DNN-CSEs are provided.These estimators are promising for 5G and future communication systems because they can analyze large amounts of data,discover statistical dependencies,learn correlations between features,and generalize the gotten knowledge.展开更多
The aim of the current study was to investigate the pharmacological activity of glabridinon the isolated human saphenous vein (SV) and explore the underlying mechanisms. Samples of patients' SVs were removed durin...The aim of the current study was to investigate the pharmacological activity of glabridinon the isolated human saphenous vein (SV) and explore the underlying mechanisms. Samples of patients' SVs were removed during bypass surgery, and 4-mm lengths of the vessels were placedin Krebs solution at ±4℃ and hung in an isolated organ bath to assess their contraction/relaxationresponses. The contraction/relaxation responses were recorded to observe if the cyclic guanosinemonophosphate (cGMP)/protein kinase G (PKG) pathway mediates the relaxant effect of glabridinafter treatment with blockers like ODQ (a guanylate cyclase inhibitor), KT5823 (a PKG inhibitor),isobutylmethylxanthine [IBMX, a phosphodiesterase (PDE) inhibitor], and cantharidin [Cant,a myosin light-chain phosphatase (MLCP) inhibitor]. Moreover, nitric oxide (NO), cGMP, andPKG levels in SV tissues were determined by ELISA after incubation with glabridin, N(o)-nitro-L-arginine methyl ester (L-Name, a NO synthetase inhibitor), phenylephrine (PE), ODQ, IBMX,and KT5823. The results showed that glabridin relaxed the vascular smooth muscle of humanSV pretreated with PE in a dose-dependent manner, which was independent of the endothelium.The vasorelaxant effect of glabridin was only inhibited by iberiotoxin (IbTX), Cant, and KT5823.Glabridin increased cGMP and PKG levels in SV homogenates, whereas it did not alter the NOlevel. The enhancing efects of cGMP and PKG levels by glabridin were abolished by ODQ andKT5823. In conclusion, glabridin has a vasorelaxant effect, which is associated with the activationof BKc. channels and inhibition of PDE.展开更多
The flow boiling heat transfer characteristics of refrigerant R134 a flowing inside two different kinds of minichannels are investigated. One channel is multi-port extruded with the hydraulic diameter of 0.63 mm,and t...The flow boiling heat transfer characteristics of refrigerant R134 a flowing inside two different kinds of minichannels are investigated. One channel is multi-port extruded with the hydraulic diameter of 0.63 mm,and the other one is rectangular with offset fins and a hydraulic diameter of 1.28 mm. The experiments are performed with a mass flow rate between 68 and 630 kg/(m^2·s),a heat flux between 9 and 64 kW/m^2,and a saturation pressure between 0.24 and 0.63 MPa,under the constant heat flux heating mode. It is found that the effect of mass flow rate on boiling heat transfer is related to heat flux,and that with the increase of heat flux,the effect can only be efficient in higher vapor quality region. The effects of heat flux and saturation pressure on boiling heat transfer are related to a threshold vapor quality,and the value will gradually decrease with the increase of heat flux or saturation pressure. Based on these analyses,a new correlation is proposed to predict the boiling heat transfer coefficient of refrigerant R134 a in the mini-channels under the experimental conditions.展开更多
Time-varying channel modeling plays an important role for many applications in time-variant scenarios,while most clustering algorithms focus on static channels and cannot accurately model the channel time-evolution pr...Time-varying channel modeling plays an important role for many applications in time-variant scenarios,while most clustering algorithms focus on static channels and cannot accurately model the channel time-evolution properties.In this paper,a fuzzy clustering algorithm based on multipath component(MPC)trajectory is proposed.Firstly,both the distance and velocity similarities of the MPCs in different snapshots are taken into account to track the MPC trajectory,in which the fuzzy scheme and a kernel function are used to calculate the distance and velocity similarities,respectively.Secondly,a fuzzy MPC trajectory clustering algorithm is proposed to cluster the MPCs in multiple snapshots.The MPCs in a snapshot are clustered according to the membership,which is defined as the probability that a MPC belongs to different clusters.Finally,time-varying channels at 28 GHz are simulated to validate the performance of our proposed algorithm.The results show that our proposed algorithm is able to accurately identify the clusters in time-varying channels compared with the existing clustering algorithms.展开更多
As a member of the inwardly rectifying channel (Kir) family, Kir2.1 allows to influx the cell more easily than to efflux, a biophysical phenomenon named inward rectification. The function of Kir2.1 is to set the resti...As a member of the inwardly rectifying channel (Kir) family, Kir2.1 allows to influx the cell more easily than to efflux, a biophysical phenomenon named inward rectification. The function of Kir2.1 is to set the resting membrane potential and modulate membrane excitability. It has been reported that residue E224 plays a key role in regulating inward rectification. The mutant Kir2.1 (E224G) displays weaker inward rectification than the WT channel. Gating of Kir2.1 depends on the membrane lipid, PIP<sub>2</sub>, such that the channel gates are closed in the absence of PIP<sub>2</sub>. Here we perform electrophysiological and computational approaches, and demonstrate that E224 also plays an important role in the PIP<sub>2</sub>-dependent activation of Kir2.1 in addition to its influence on inward rectification. The E224G mutant takes 4.5 times longer to be activated by PIP<sub>2</sub>. To probe the mechanism by which E224G slows the channel opening kinetics, we perform targeted molecular dynamics simulations and find that the mutant weakens the interactions between CD-loop and C-linker (H221-R189) and the adjacent G-loops (R312-E303) which are thought to stabilize the open state of the channel in our previous work. These data provide new insights into the regulation of Kir2.1 channel activity and suggest that a common mechanism may be involved in the distinct biophysical processes, such as inward rectification and PIP<sub>2</sub>-induced gating.展开更多
Objectives To investigate the effect of Gαq/11 signaling pathway and ATP-sensitive potassium channel ( KATP channel ) on ischemic preconditioning (IPC) protection in rat hearts. Methods Two series of experiments were...Objectives To investigate the effect of Gαq/11 signaling pathway and ATP-sensitive potassium channel ( KATP channel ) on ischemic preconditioning (IPC) protection in rat hearts. Methods Two series of experiments were performed in Wistar rat hearts. In the first series of experiment, ischemic preconditioning was induced by left anterior descending occlusion (three, 5 min episodes separated by 5 min of reperfusion), ischemia-reperfusion injury was induced by 30 min coronary artery occlusion followed by 90 min reperfusion. Hemodynamics, infarct size and scores of ventricular arrhythmias were measured. The expression of Gαq/11 protein in the heart was measured by Western blot analysis in the second series. Results Ischemic preconditioning rats showed decreased infarct size and scores of ventricular arrhythmia vs non-IP control rats. The effect of IPC was significantly attenuated by glibenclamide (1 mg/kg, ip), a nonselective KATP channel inhibitor. IPC caused a significant increase in the expression of Gαq/11 protein. Conclusions Activations of Gαq/11 signal pathway and KATP channel played significant roles in the classical cardioprotection of ischemic precon-ditioning rat heart and might be an important mechanism of signal transduction pathway during the ischemic preconditioning.展开更多
The channel lateral pocket or halo region of NMOSFET characterized by interface state R G current of a forward gated diode has been investigated numerically for the first time.The result of numerical analysis demons...The channel lateral pocket or halo region of NMOSFET characterized by interface state R G current of a forward gated diode has been investigated numerically for the first time.The result of numerical analysis demonstrates that the effective surface doping concentration and the interface state density of the pocket or halo region are interface states R G current peak position dependent and amplitude dependent,respectively.It can be expressed quantitatively according to the device physics knowledge,thus,the direct characterization of the interface state density and the effective surface doping concentration of the pocket or halo becomes very easy.展开更多
基金supported by the National Science Fund for Distinguished Young Scholars(No.61925102)the National Natural Science Foundation of China(No.62201086,92167202,62201087,62101069)BUPT-CMCC Joint Innovation Center,and State Key Laboratory of IPOC(BUPT)(No.IPOC2023ZT02),China。
文摘Visible light communication(VLC)has attracted much attention in the research of sixthgeneration(6G)systems.Furthermore,channel modeling is the foundation for designing efficient and robust VLC systems.In this paper,we present extensive VLC channel measurement campaigns in indoor environments,i.e.,an office and a corridor.Based on the measured data,the large-scale fading characteristics and multipath-related characteristics,including omnidirectional optical path loss(OPL),K-factor,power angular spectrum(PAS),angle spread(AS),and clustering characteristics,are analyzed and modeled through a statistical method.Based on the extracted statistics of the above-mentioned channel characteristics,we propose a statistical spatial channel model(SSCM)capable of modeling multipath in the spatial domain.Furthermore,the simulated statistics of the proposed model are compared with the measured statistics.For instance,in the office,the simulated path loss exponent(PLE)and the measured PLE are 1.96and 1.97,respectively.And,the simulated medians of AS and measured medians of AS are 25.94°and 24.84°,respectively.Generally,the fact that the simulated results fit well with measured results has demonstrated the accuracy of our SSCM.
基金supported by the Key Research and Development Program of China(No.2022YFC3005401)Key Research and Development Program of China,Yunnan Province(No.202203AA080009,202202AF080003)Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX21_0482).
文摘In Beyond the Fifth Generation(B5G)heterogeneous edge networks,numerous users are multiplexed on a channel or served on the same frequency resource block,in which case the transmitter applies coding and the receiver uses interference cancellation.Unfortunately,uncoordinated radio resource allocation can reduce system throughput and lead to user inequity,for this reason,in this paper,channel allocation and power allocation problems are formulated to maximize the system sum rate and minimum user achievable rate.Since the construction model is non-convex and the response variables are high-dimensional,a distributed Deep Reinforcement Learning(DRL)framework called distributed Proximal Policy Optimization(PPO)is proposed to allocate or assign resources.Specifically,several simulated agents are trained in a heterogeneous environment to find robust behaviors that perform well in channel assignment and power allocation.Moreover,agents in the collection stage slow down,which hinders the learning of other agents.Therefore,a preemption strategy is further proposed in this paper to optimize the distributed PPO,form DP-PPO and successfully mitigate the straggler problem.The experimental results show that our mechanism named DP-PPO improves the performance over other DRL methods.
基金This research project was funded by the Deanship of Scientific Research,Princess Nourah bint Abdulrahman University,through the Program of Research Project Funding After Publication,grant No(43-PRFA-P-58).
文摘This study presents a layered generalization ensemble model for next generation radio mobiles,focusing on supervised channel estimation approaches.Channel estimation typically involves the insertion of pilot symbols with a well-balanced rhythm and suitable layout.The model,called Stacked Generalization for Channel Estimation(SGCE),aims to enhance channel estimation performance by eliminating pilot insertion and improving throughput.The SGCE model incorporates six machine learning methods:random forest(RF),gradient boosting machine(GB),light gradient boosting machine(LGBM),support vector regression(SVR),extremely randomized tree(ERT),and extreme gradient boosting(XGB).By generating meta-data from five models(RF,GB,LGBM,SVR,and ERT),we ensure accurate channel coefficient predictions using the XGB model.To validate themodeling performance,we employ the leave-one-out cross-validation(LOOCV)approach,where each observation serves as the validation set while the remaining observations act as the training set.SGCE performances’results demonstrate higher mean andmedian accuracy compared to the separatedmodel.SGCE achieves an average accuracy of 98.4%,precision of 98.1%,and the highest F1-score of 98.5%,accurately predicting channel coefficients.Furthermore,our proposedmethod outperforms prior traditional and intelligent techniques in terms of throughput and bit error rate.SGCE’s superior performance highlights its efficacy in optimizing channel estimation.It can effectively predict channel coefficients and contribute to enhancing the overall efficiency of radio mobile systems.Through extensive experimentation and evaluation,we demonstrate that SGCE improved performance in channel estimation,surpassing previous techniques.Accordingly,SGCE’s capabilities have significant implications for optimizing channel estimation in modern communication systems.
基金This research was supported by Science and Technology Research Project of Education Department of Jiangxi Province,China(Nos.GJJ2206701,GJJ2206717).
文摘The current resource allocation in 5G vehicular networks for mobile cloud communication faces several challenges,such as low user utilization,unbalanced resource allocation,and extended adaptive allocation time.We propose an adaptive allocation algorithm for mobile cloud communication resources in 5G vehicular networks to address these issues.This study analyzes the components of the 5G vehicular network architecture to determine the performance of different components.It is ascertained that the communication modes in 5G vehicular networks for mobile cloud communication include in-band and out-of-band modes.Furthermore,this study analyzes the single-hop and multi-hop modes in mobile cloud communication and calculates the resource transmission rate and bandwidth in different communication modes.The study also determines the scenario of one-way and two-way vehicle lane cloud communication network connectivity,calculates the probability of vehicle network connectivity under different mobile cloud communication radii,and determines the amount of cloud communication resources required by vehicles in different lane scenarios.Based on the communication status of users in 5G vehicular networks,this study calculates the bandwidth and transmission rate of the allocated channels using Shannon’s formula.It determines the adaptive allocation of cloud communication resources,introduces an objective function to obtain the optimal solution after allocation,and completes the adaptive allocation process.The experimental results demonstrate that,with the application of the proposed method,the maximum utilization of user communication resources reaches approximately 99%.The balance coefficient curve approaches 1,and the allocation time remains under 2 s.This indicates that the proposed method has higher adaptive allocation efficiency.
基金supported by the EURAMET European Partnership on Metrology(EPM),under the 21NRM03 Metrology for Emerging Wireless Standards(MEWS)projectThe project(21NRM03 MEWS)has received funding from the EPM,co-financed from the European Union’s Horizon Europe Research and Innovation Programme,and by the Participating States。
文摘Due to the large amount of unused and unexplored spectrum resources, the so-called subTerahertz(sub-THz) frequency bands from 100 to 300 GHz are seen as promising bands for the next generation of wireless communication systems. Channel modeling at sub-THz bands is essential for the design and deployment of future wireless communication systems. Channel measurement is a widely adopted method to obtain channel characteristics and establish mathematical channel models. Channel measurements depend on the design and construction of channel sounders. Thus, reliable channel sounding techniques and accurate channel measurements are required. In this paper, the requirements of an ideal channel sounder are discussed and the main channel sounding techniques are described for the subTHz frequency bands. The state-of-the-art sub-THz channel sounders reported in the literature and respective channel measurements are presented. Moreover, a vector network analyzer(VNA) based channel sounder, which supports frequency bands from 220 to330 GHz is presented and its performance capability and limitation are evaluated. This paper also discussed the challenge and future outlook of the sub-THz channel sounders and measurements.
文摘In this paper,ambient IoT is used as a typical use case of massive connections for the sixth generation(6G)mobile communications where we derive the performance requirements to facilitate the evaluation of technical solutions.A rather complete design of unsourced multiple access is proposed in which two key parts:a compressed sensing module for active user detection,and a sparse interleaver-division multiple access(SIDMA)module are simulated side by side on a same platform at balanced signal to noise ratio(SNR)operating points.With a proper combination of compressed sensing matrix,a convolutional encoder,receiver algorithms,the simulated performance results appear superior to the state-of-the-art benchmark,yet with relatively less complicated processing.
基金supported by the National Natural Science Foundation of China under Grant No.61901523 and No.62071488.
文摘This paper investigates the Quality of Experience(QoE)oriented channel access anti-jamming problem in 5th Generation Mobile Communication(5G)ultra-dense networks.Firstly,considering that the 5G base station adopts beamforming technology,an anti-jamming model under Space Division Multiple Access(SDMA)conditions is proposed.Secondly,the confrontational relationship between users and the jammer is formulated as a Stackelberg game.Besides,to achieve global optimization,we design a local cooperation mechanism for users and formulate the cooperation and competition among users as a local altruistic game.By proving that the local altruistic game is an Exact Potential Game(EPG),we further prove the existence of pure strategy Nash Equilibrium(NE)among users and Stackelberg Equilibrium(SE)between users and jammer.Thirdly,to obtain the equilibrium solutions of the proposed games,we propose an anti-jamming channel selection algorithm and improve its convergence speed through heterogeneous learning parameters.The simulation results validate the convergence and effectiveness of the proposed algorithm.Compared with the throughput optimization scheme,our proposed scheme obtain a greater network satisfaction rate.Finally,we also analyze user fairness changes during the algorithm convergence process and get some interesting conclusions.
基金funded by Taif University Researchers Supporting Project No.(TURSP-2020/214),Taif University,Taif,Saudi Arabia。
文摘For a 5G wireless communication system,a convolutional deep neural network(CNN)is employed to synthesize a robust channel state estimator(CSE).The proposed CSE extracts channel information from transmit-and-receive pairs through offline training to estimate the channel state information.Also,it utilizes pilots to offer more helpful information about the communication channel.The proposedCNN-CSE performance is compared with previously published results for Bidirectional/long short-term memory(BiLSTM/LSTM)NNs-based CSEs.The CNN-CSE achieves outstanding performance using sufficient pilots only and loses its functionality at limited pilots compared with BiLSTM and LSTM-based estimators.Using three different loss function-based classification layers and the Adam optimization algorithm,a comparative study was conducted to assess the performance of the presented DNNs-based CSEs.The BiLSTM-CSE outperforms LSTM,CNN,conventional least squares(LS),and minimum mean square error(MMSE)CSEs.In addition,the computational and learning time complexities for DNN-CSEs are provided.These estimators are promising for 5G and future communication systems because they can analyze large amounts of data,discover statistical dependencies,learn correlations between features,and generalize the gotten knowledge.
文摘The aim of the current study was to investigate the pharmacological activity of glabridinon the isolated human saphenous vein (SV) and explore the underlying mechanisms. Samples of patients' SVs were removed during bypass surgery, and 4-mm lengths of the vessels were placedin Krebs solution at ±4℃ and hung in an isolated organ bath to assess their contraction/relaxationresponses. The contraction/relaxation responses were recorded to observe if the cyclic guanosinemonophosphate (cGMP)/protein kinase G (PKG) pathway mediates the relaxant effect of glabridinafter treatment with blockers like ODQ (a guanylate cyclase inhibitor), KT5823 (a PKG inhibitor),isobutylmethylxanthine [IBMX, a phosphodiesterase (PDE) inhibitor], and cantharidin [Cant,a myosin light-chain phosphatase (MLCP) inhibitor]. Moreover, nitric oxide (NO), cGMP, andPKG levels in SV tissues were determined by ELISA after incubation with glabridin, N(o)-nitro-L-arginine methyl ester (L-Name, a NO synthetase inhibitor), phenylephrine (PE), ODQ, IBMX,and KT5823. The results showed that glabridin relaxed the vascular smooth muscle of humanSV pretreated with PE in a dose-dependent manner, which was independent of the endothelium.The vasorelaxant effect of glabridin was only inhibited by iberiotoxin (IbTX), Cant, and KT5823.Glabridin increased cGMP and PKG levels in SV homogenates, whereas it did not alter the NOlevel. The enhancing efects of cGMP and PKG levels by glabridin were abolished by ODQ andKT5823. In conclusion, glabridin has a vasorelaxant effect, which is associated with the activationof BKc. channels and inhibition of PDE.
文摘The flow boiling heat transfer characteristics of refrigerant R134 a flowing inside two different kinds of minichannels are investigated. One channel is multi-port extruded with the hydraulic diameter of 0.63 mm,and the other one is rectangular with offset fins and a hydraulic diameter of 1.28 mm. The experiments are performed with a mass flow rate between 68 and 630 kg/(m^2·s),a heat flux between 9 and 64 kW/m^2,and a saturation pressure between 0.24 and 0.63 MPa,under the constant heat flux heating mode. It is found that the effect of mass flow rate on boiling heat transfer is related to heat flux,and that with the increase of heat flux,the effect can only be efficient in higher vapor quality region. The effects of heat flux and saturation pressure on boiling heat transfer are related to a threshold vapor quality,and the value will gradually decrease with the increase of heat flux or saturation pressure. Based on these analyses,a new correlation is proposed to predict the boiling heat transfer coefficient of refrigerant R134 a in the mini-channels under the experimental conditions.
基金supported by the National Key Laboratory of Electromagnetic Environment(No.202101004)the National Nature Science of China(NSFC)(No.61931001),respectively。
文摘Time-varying channel modeling plays an important role for many applications in time-variant scenarios,while most clustering algorithms focus on static channels and cannot accurately model the channel time-evolution properties.In this paper,a fuzzy clustering algorithm based on multipath component(MPC)trajectory is proposed.Firstly,both the distance and velocity similarities of the MPCs in different snapshots are taken into account to track the MPC trajectory,in which the fuzzy scheme and a kernel function are used to calculate the distance and velocity similarities,respectively.Secondly,a fuzzy MPC trajectory clustering algorithm is proposed to cluster the MPCs in multiple snapshots.The MPCs in a snapshot are clustered according to the membership,which is defined as the probability that a MPC belongs to different clusters.Finally,time-varying channels at 28 GHz are simulated to validate the performance of our proposed algorithm.The results show that our proposed algorithm is able to accurately identify the clusters in time-varying channels compared with the existing clustering algorithms.
基金Supported by the National Natural Science Foundation for Distinguished Young Scholars of Hebei Province under Grant Nos C2015202340 and C2013202244the Foundation for Outstanding Talents of Hebei Province under Grant No C201400305+3 种基金the National Natural Science Foundation of China under Grant Nos 11247010,11175055,11475053,11347017,31400711 and 11647121the NIH R01 under Grant No HL059949-18the Foundation for the Science and Technology Program of Higher Education Institutions of Hebei Province under Grant No QN2016113the Scientific Innovation Fund for Excellent Young Scientists of Hebei University of Technology under Grant No 2015010
文摘As a member of the inwardly rectifying channel (Kir) family, Kir2.1 allows to influx the cell more easily than to efflux, a biophysical phenomenon named inward rectification. The function of Kir2.1 is to set the resting membrane potential and modulate membrane excitability. It has been reported that residue E224 plays a key role in regulating inward rectification. The mutant Kir2.1 (E224G) displays weaker inward rectification than the WT channel. Gating of Kir2.1 depends on the membrane lipid, PIP<sub>2</sub>, such that the channel gates are closed in the absence of PIP<sub>2</sub>. Here we perform electrophysiological and computational approaches, and demonstrate that E224 also plays an important role in the PIP<sub>2</sub>-dependent activation of Kir2.1 in addition to its influence on inward rectification. The E224G mutant takes 4.5 times longer to be activated by PIP<sub>2</sub>. To probe the mechanism by which E224G slows the channel opening kinetics, we perform targeted molecular dynamics simulations and find that the mutant weakens the interactions between CD-loop and C-linker (H221-R189) and the adjacent G-loops (R312-E303) which are thought to stabilize the open state of the channel in our previous work. These data provide new insights into the regulation of Kir2.1 channel activity and suggest that a common mechanism may be involved in the distinct biophysical processes, such as inward rectification and PIP<sub>2</sub>-induced gating.
文摘Objectives To investigate the effect of Gαq/11 signaling pathway and ATP-sensitive potassium channel ( KATP channel ) on ischemic preconditioning (IPC) protection in rat hearts. Methods Two series of experiments were performed in Wistar rat hearts. In the first series of experiment, ischemic preconditioning was induced by left anterior descending occlusion (three, 5 min episodes separated by 5 min of reperfusion), ischemia-reperfusion injury was induced by 30 min coronary artery occlusion followed by 90 min reperfusion. Hemodynamics, infarct size and scores of ventricular arrhythmias were measured. The expression of Gαq/11 protein in the heart was measured by Western blot analysis in the second series. Results Ischemic preconditioning rats showed decreased infarct size and scores of ventricular arrhythmia vs non-IP control rats. The effect of IPC was significantly attenuated by glibenclamide (1 mg/kg, ip), a nonselective KATP channel inhibitor. IPC caused a significant increase in the expression of Gαq/11 protein. Conclusions Activations of Gαq/11 signal pathway and KATP channel played significant roles in the classical cardioprotection of ischemic precon-ditioning rat heart and might be an important mechanism of signal transduction pathway during the ischemic preconditioning.
文摘The channel lateral pocket or halo region of NMOSFET characterized by interface state R G current of a forward gated diode has been investigated numerically for the first time.The result of numerical analysis demonstrates that the effective surface doping concentration and the interface state density of the pocket or halo region are interface states R G current peak position dependent and amplitude dependent,respectively.It can be expressed quantitatively according to the device physics knowledge,thus,the direct characterization of the interface state density and the effective surface doping concentration of the pocket or halo becomes very easy.