Five patients treated for intracranial cerebral hemorrhage after superficial temporal artery-middle cerebral artery bypass in Xuwu Hospital, Capital Medical University, Beijing, China, from 2005-2011 were included in ...Five patients treated for intracranial cerebral hemorrhage after superficial temporal artery-middle cerebral artery bypass in Xuwu Hospital, Capital Medical University, Beijing, China, from 2005-2011 were included in this study. Prior to superficial temporal artery-middle cerebral artery bypass, all patients showed diminished cerebrovascular reactivity and an ipsilateral ischemic lesion. Intracranial cerebral hemorrhage developed within 1-4 days following superficial temporal artery-middle cerebral artery bypass. Transcranial Doppler showed increased middle cerebral artery velocity of 50-100% in the operated hemisphere. These findings suggested that focal hyperperfusion, an ipsilateral ischemic lesion and diminished cerebrovascular reactivity are the important characteristics of intracerebral hemorrhage following superficial temporal artery-middle cerebral artery bypass in patients with steno-occlusive cerebrovascular disease.展开更多
Our previous ifndings have demonstrated that acupuncture at the Taixi （KI3） acupoint in healthy youths can activate neurons in cognitive-related cerebral cortex. Here, we investigated whether acupuncture at this acu...Our previous ifndings have demonstrated that acupuncture at the Taixi （KI3） acupoint in healthy youths can activate neurons in cognitive-related cerebral cortex. Here, we investigated whether acupuncture at this acupoint in elderly patients with mild cognitive impairment can also activate neurons in these regions. Resting state and task-related functional magnetic resonance imaging showed that the pinprick senstation of acupuncture at the Taixi acupoint differed signiifcantly between elderly patients with mild cognitive impairment and healthy elderly controls. Results showed that 20 brain regions were activated in both groups of participants, including the bi-lateral anterior cingulate gyrus （Brodmann areas [BA] 32, 24）, left medial frontal cortex （BA 9, 10, 11）, left cuneus （BA 19）, left middle frontal gyrus （BA 11）, left lingual gyrus （BA 18）, right medial frontal gyrus （BA 11）, bilateral inferior frontal gyrus （BA 47）, left superior frontal gyrus （BA11）, right cuneus （BA 19, 18）, right superior temporal gyrus （BA 38）, left subcallosal gyrus （BA 47）, bilateral precuneus （BA 19）, right medial frontal gyrus （BA 10）, right superior frontal （BA 11）, left cingulate gyrus （BA 32）, left precentral gyrus （BA 6）, and right fusiform gyrus （BA 19）. These results suggest that acupuncture at the Taixi acupoint in elderly patients with mild cogni-tive impairment can also activate some brain regions.展开更多
The microstructure and the stability of carbides after heat treatments in an H23 tool steel were investigated. The heat treatments consisted of austenization at two different austenizing temperatures （1100℃ and 125...The microstructure and the stability of carbides after heat treatments in an H23 tool steel were investigated. The heat treatments consisted of austenization at two different austenizing temperatures （1100℃ and 1250℃）, followed by water quenching and double-aging at 650℃, 750℃, and 800℃with air cooling between the first and second aging treatments. Martensite did not form in the as-quenched micro- structures, which consisted of a ferrite matrix, M6C, M7C3, and MC carbides. The double-aged microstructures consisted of a ferrite matrix and MC, M6C, M7C3, and M23C6 carbides. Secondary hardening as a consequence of secondary precipitation of fine M2C carbides did not occur. There was disagreement between the experimental microstructure and the results of thermodynamic calculations. The highest double-aged hardness of the H23 tool steel was 448 HV after austenization at 1250℃ and double-aging at 650℃, which suggested that this tool steel should be used at temperatures below 650℃.展开更多
根据超声心动图准确分析左心室轮廓和射血分数对于心血管疾病诊断意义重大.但现有方法存在左心室分割和射血分数预测之间缺乏关联性、左心室分割关键点易于出现离群点和突变点、方法存储和计算开销大、解释性不佳等问题,为此提出一种基...根据超声心动图准确分析左心室轮廓和射血分数对于心血管疾病诊断意义重大.但现有方法存在左心室分割和射血分数预测之间缺乏关联性、左心室分割关键点易于出现离群点和突变点、方法存储和计算开销大、解释性不佳等问题,为此提出一种基于先验知识引导的轻量级图卷积方法EchoGPK(Echo Guided by Priori Knowledge),以心脏的结构和运动特性、相邻心肌的相似性等先验知识为引导,设计了计算高效的螺旋聚合函数和深度压缩的多头偏心聚合解码器,实现了图卷积结构的轻量化.方法基于临床医生的普遍经验提出了适度利用左心室轮廓的多任务射血分数预测网络,建立了左心室分割和射血分数预测之间的关联性,增强了推理的可解释性;基于图卷积神经网络的传递特性约束邻居点的行为,减少了边界离群点和突变点的产生.EchoGPK在大型公开数据集EchoNet-Dynamic上的实验结果表明,左心室分割的Dice分数达92.13%,射血分数预测的MAE达3.92%;方法表现出准确率高、参数量和算力需求低等特点,证明了先验知识在超声医学图像分析中的有效性.展开更多
基金supported by the National Key Project of Scientific and Technical Supporting Program Funded by the Ministry of Science and Technology of China during the 12~th Five-Year Development Period,No.2011BAI08B04
文摘Five patients treated for intracranial cerebral hemorrhage after superficial temporal artery-middle cerebral artery bypass in Xuwu Hospital, Capital Medical University, Beijing, China, from 2005-2011 were included in this study. Prior to superficial temporal artery-middle cerebral artery bypass, all patients showed diminished cerebrovascular reactivity and an ipsilateral ischemic lesion. Intracranial cerebral hemorrhage developed within 1-4 days following superficial temporal artery-middle cerebral artery bypass. Transcranial Doppler showed increased middle cerebral artery velocity of 50-100% in the operated hemisphere. These findings suggested that focal hyperperfusion, an ipsilateral ischemic lesion and diminished cerebrovascular reactivity are the important characteristics of intracerebral hemorrhage following superficial temporal artery-middle cerebral artery bypass in patients with steno-occlusive cerebrovascular disease.
基金supported by the National Natural Science Foundation of China,No.81173354the Natural Science Foundation of Guangdong Province,No.10451810101005862+1 种基金a grant from Guangdong Administration of Traditional Chinese Medicine,No.20111032,20132019the Science and Technology Plan Project of Baoan District,Shenzhen City,No.200902159
文摘Our previous ifndings have demonstrated that acupuncture at the Taixi （KI3） acupoint in healthy youths can activate neurons in cognitive-related cerebral cortex. Here, we investigated whether acupuncture at this acupoint in elderly patients with mild cognitive impairment can also activate neurons in these regions. Resting state and task-related functional magnetic resonance imaging showed that the pinprick senstation of acupuncture at the Taixi acupoint differed signiifcantly between elderly patients with mild cognitive impairment and healthy elderly controls. Results showed that 20 brain regions were activated in both groups of participants, including the bi-lateral anterior cingulate gyrus （Brodmann areas [BA] 32, 24）, left medial frontal cortex （BA 9, 10, 11）, left cuneus （BA 19）, left middle frontal gyrus （BA 11）, left lingual gyrus （BA 18）, right medial frontal gyrus （BA 11）, bilateral inferior frontal gyrus （BA 47）, left superior frontal gyrus （BA11）, right cuneus （BA 19, 18）, right superior temporal gyrus （BA 38）, left subcallosal gyrus （BA 47）, bilateral precuneus （BA 19）, right medial frontal gyrus （BA 10）, right superior frontal （BA 11）, left cingulate gyrus （BA 32）, left precentral gyrus （BA 6）, and right fusiform gyrus （BA 19）. These results suggest that acupuncture at the Taixi acupoint in elderly patients with mild cogni-tive impairment can also activate some brain regions.
基金the Directorate of Higher Education, Indonesian Government and to the Institut Teknologi Nasional (Itenas), Bandung, Indonesia for their financial support
文摘The microstructure and the stability of carbides after heat treatments in an H23 tool steel were investigated. The heat treatments consisted of austenization at two different austenizing temperatures （1100℃ and 1250℃）, followed by water quenching and double-aging at 650℃, 750℃, and 800℃with air cooling between the first and second aging treatments. Martensite did not form in the as-quenched micro- structures, which consisted of a ferrite matrix, M6C, M7C3, and MC carbides. The double-aged microstructures consisted of a ferrite matrix and MC, M6C, M7C3, and M23C6 carbides. Secondary hardening as a consequence of secondary precipitation of fine M2C carbides did not occur. There was disagreement between the experimental microstructure and the results of thermodynamic calculations. The highest double-aged hardness of the H23 tool steel was 448 HV after austenization at 1250℃ and double-aging at 650℃, which suggested that this tool steel should be used at temperatures below 650℃.
文摘根据超声心动图准确分析左心室轮廓和射血分数对于心血管疾病诊断意义重大.但现有方法存在左心室分割和射血分数预测之间缺乏关联性、左心室分割关键点易于出现离群点和突变点、方法存储和计算开销大、解释性不佳等问题,为此提出一种基于先验知识引导的轻量级图卷积方法EchoGPK(Echo Guided by Priori Knowledge),以心脏的结构和运动特性、相邻心肌的相似性等先验知识为引导,设计了计算高效的螺旋聚合函数和深度压缩的多头偏心聚合解码器,实现了图卷积结构的轻量化.方法基于临床医生的普遍经验提出了适度利用左心室轮廓的多任务射血分数预测网络,建立了左心室分割和射血分数预测之间的关联性,增强了推理的可解释性;基于图卷积神经网络的传递特性约束邻居点的行为,减少了边界离群点和突变点的产生.EchoGPK在大型公开数据集EchoNet-Dynamic上的实验结果表明,左心室分割的Dice分数达92.13%,射血分数预测的MAE达3.92%;方法表现出准确率高、参数量和算力需求低等特点,证明了先验知识在超声医学图像分析中的有效性.
