Achievements are presented for truss models of RC structures developed in previous years: 1. Two constitutive models, biaxial and triaxial, are based on regular trusses, with bars obeying nonlinear uniaxial σ-ε laws...Achievements are presented for truss models of RC structures developed in previous years: 1. Two constitutive models, biaxial and triaxial, are based on regular trusses, with bars obeying nonlinear uniaxial σ-ε laws of material under simulation;both models have been compared with test results and show a dependence of Poisson ratio on curvature of σ-ε law. 2. A truss finite element has been used in the nonlinear static and dynamic analysis of plane RC frames;it has been compared with test results and describes, in a simple way, the formation of plastic hinges. 3. Thanks to the very simple geometry of a truss, the equilibrium equations can be easily written and the stiffness matrix can be easily updated, both with respect to the deformed truss, within each step of a static incremental loading or within each time step of a dynamic analysis, so that to take into account geometric nonlinearities. So the confinement of a RC column is interpreted as a structural stability effect of concrete. And a significant role of the transverse reinforcement is revealed, that of preventing, by its close spacing and sufficient amount, the buckling of inner longitudinal concrete struts, which would lead to a global instability of the RC column. 4. The proposed truss model is statically indeterminate, so it exhibits some features, which are not met by the “strut-and-tie” model.展开更多
Zeolitic imidazolate frameworks(ZIFs)as smart drug delivery systems with microenvironment-triggered release have attracted much attention for tumor therapy.However,the exploration of ZIFs in biomedicine still encounte...Zeolitic imidazolate frameworks(ZIFs)as smart drug delivery systems with microenvironment-triggered release have attracted much attention for tumor therapy.However,the exploration of ZIFs in biomedicine still encounters many issues,such as inconvenient surface modification,fast drug release during blood circulation,undesired damage to major organs,and severe in vivo toxicity.To address the above issues,we developed an Mn-ZIF-90 nanosystem functionalized with an originally designed active-targeting and pH-responsive magnetic resonance imaging(MRI)Y1 receptor ligand[Asn28,Pro30,Trp32]-NPY(25-36)for imaging-guided tumor therapy.After Y1 receptor ligand modification,the Mn-ZIF-90 nanosystem exhibited high drug loading,better blood circulation stability,and dual breast cancer cell membrane and mitochondria targetability,further favoring specific microenvironment-triggered tumor therapy.Meanwhile,this nanosystem showed promising T1-weighted magnetic resonance imaging contrast in vivo in the tumor sites.Especially,this nanosystem with fast clean-up had almost no obvious toxicity and no damage occurred to the major organs in mice.Therefore,this nanosystem shows potential for use in imaging-guided tumor therapy.展开更多
Changes and reconfiguration of information systems(ISs)are two kernel concepts of rapidil reconfigurable in-formation system(RRIS).It is the abilitise to evolve with changes that make RRIS superior to the traditional ...Changes and reconfiguration of information systems(ISs)are two kernel concepts of rapidil reconfigurable in-formation system(RRIS).It is the abilitise to evolve with changes that make RRIS superior to the traditional ISs.Hierarchical architecture of RRIS is put forward.And then a component-based framework of RRIS is discussed including its building and designing in detail.展开更多
A novel coordination polymer of [Ca(2-OPA)2(H2O)2]n (2-OPA-=2-oxo-1(4H)-pyridineacetate anion) was synthesized and characterized by elemental analysis, IR, TG and single crystal X-ray diffraction. The title complex cr...A novel coordination polymer of [Ca(2-OPA)2(H2O)2]n (2-OPA-=2-oxo-1(4H)-pyridineacetate anion) was synthesized and characterized by elemental analysis, IR, TG and single crystal X-ray diffraction. The title complex crystallizes in orthorhombic with space group Pna21, a=0.799 96(16) nm, b=0.823 77(16) nm, c=2.415 3(5) nm, V=1.591 6(6) nm3, Z=4, R=0.030 3, wR=0.070 0. The Ca atom is eight-coordinated by six O atoms of four 2-OPA- ligands and two water molecules, and displays a dodecahedron coordination geometry. Each 2-OPA- ligand bridges two adjacent Ca atoms, forming a infinite chain along the a direction. The Ca...Ca distance is 0.4102 2(8)nm. A two-dimensional supramolecular framework is further constructed by the hydrogen bonds and the weak π-π interactions. The results of TG analysis show the chain structure of the title complex was stable under 297.5 ℃. CCDC: 251669.展开更多
In this paper, a new class of over-relaxed proximal point algorithms for solving nonlinear operator equations with (A,η,m)-monotonicity framework in Hilbert spaces is introduced and studied. Further, by using the gen...In this paper, a new class of over-relaxed proximal point algorithms for solving nonlinear operator equations with (A,η,m)-monotonicity framework in Hilbert spaces is introduced and studied. Further, by using the generalized resolvent operator technique associated with the (A,η,m)-monotone operators, the approximation solvability of the operator equation problems and the convergence of iterative sequences generated by the algorithm are discussed. Our results improve and generalize the corresponding results in the literature.展开更多
The Paris Agreement proposed to keep the increase in global average temperature to well below 2 ℃ abovepre-industrial levels and to pursue efforts to limit the temperature increase to 1.5 ℃ above pre-industriallevel...The Paris Agreement proposed to keep the increase in global average temperature to well below 2 ℃ abovepre-industrial levels and to pursue efforts to limit the temperature increase to 1.5 ℃ above pre-industriallevels. It was thus the first international treaty to endow the 2 ℃ global temperature target with legal effect.The qualitative expression of the ultimate objective in Article 2 of the United Nations Framework Conventionon Climate Change （UNFCCC） has now evolved into the numerical temperature rise target in Article 2 of theParis Agreement. Starting with the Second Assessment Report （SAR） of the Intergovernmental Panel on Cli-mate Change （IPCC）, an important task for subsequent assessments has been to provide scientific informa-tion to help determine the quantified long-term goal for UNFCCC negotiation. However, due to involvementin the value judgment within the scope of non-scientific assessment, the IPCC has never scientifically af-firmed the unacceptable extent of global temperature rise. The setting of the long-term goal for addressingclimate change has been a long process, and the 2 ℃ global temperature target is the political consensuson the basis of scientific assessment. This article analyzes the evolution of the long-term global goal foraddressing climate change and its impact on scientific assessment, negotiation processes, and global low-carbon development, from aspects of the origin of the target, the series of assessments carried out by the 1PCCfocusing on Article 2 of the UNFCCC, and the promotion of the global temperature goal at the political level.展开更多
The tremendous growth of the cloud computing environments requires new architecture for security services. Cloud computing is the utilization of many servers/data centers or cloud data storages (CDSs) housed in many d...The tremendous growth of the cloud computing environments requires new architecture for security services. Cloud computing is the utilization of many servers/data centers or cloud data storages (CDSs) housed in many different locations and interconnected by high speed networks. CDS, like any other emerging technology, is experiencing growing pains. It is immature, it is fragmented and it lacks standardization. Although security issues are delaying its fast adoption, cloud computing is an unstoppable force and we need to provide security mechanisms to ensure its secure adoption. In this paper a comprehensive security framework based on Multi-Agent System (MAS) architecture for CDS to facilitate confidentiality, correctness assurance, availability and integrity of users' data in the cloud is proposed. Our security framework consists of two main layers as agent layer and CDS layer. Our propose MAS architecture includes main five types of agents: Cloud Service Provider Agent (CSPA), Cloud Data Confidentiality Agent (CDConA), Cloud Data Correctness Agent (CDCorA), Cloud Data Availability Agent (CDAA) and Cloud Data Integrity Agent (CDIA). In order to verify our proposed security framework based on MAS architecture, pilot study is conducted using a questionnaire survey. Rasch Methodology is used to analyze the pilot data. Item reliability is found to be poor and a few respondents and items are identified as misfits with distorted measurements. As a result, some problematic questions are revised and some predictably easy questions are excluded from the questionnaire. A prototype of the system is implemented using Java. To simulate the agents, oracle database packages and triggers are used to implement agent functions and oracle jobs are utilized to create agents.展开更多
The Sun et al's training program for clinical research nurses(CRNs)in the World Journal of Clinical Cases is a comprehensive and scientific approach.It includes structured frameworks for CRN training,aiming to imp...The Sun et al's training program for clinical research nurses(CRNs)in the World Journal of Clinical Cases is a comprehensive and scientific approach.It includes structured frameworks for CRN training,aiming to improve CRN competency.This program emphasizes practical abilities,updates training content,and improves evaluation methods.The cultivation of CRN talents focuses on enhancing the training system,establishing a multifaceted evaluation framework,and continuously refining the training programs.Regular feedback and evalua-tion are essential to improve CRNs'competency in practical settings.展开更多
Higher education internationalization(HEI)has become an important priority for global decision makers and education providers.Persuaded by globalization,HEI is a political strategy and economic prospect for countries,...Higher education internationalization(HEI)has become an important priority for global decision makers and education providers.Persuaded by globalization,HEI is a political strategy and economic prospect for countries,governments,and universities to position themselves in global markets.The purpose of this paper is to provide a methodological pathway to develop a dynamic,reformed South African HEI framework based on the transformative drive(i.e.,adjustment of change,learning,shared knowledge,internationalization,globalization an institutionalized memory)of HEI in China.The interpretivist paradigm constitutes the basic research approach.Quantitative and qualitative data will be collected,analyzed,and integrated using a multiphase mixed methods approach.This approach consists of three phases including content analysis(Phase I),in-depth interviews(Phase II),and surveys(Phase III),which answers the focal research question.The significance of this research includes creating a better understanding of South African higher education(HE)policy issues from a transformational perspective,contributing to theory on how internationalization affects HE’s position in economic and social development and broadening knowledge and understanding of the unique circumstances and challenges of HEI in developing countries,particularly in countries seeking to position themselves in the globalized knowledge economy.展开更多
文摘Achievements are presented for truss models of RC structures developed in previous years: 1. Two constitutive models, biaxial and triaxial, are based on regular trusses, with bars obeying nonlinear uniaxial σ-ε laws of material under simulation;both models have been compared with test results and show a dependence of Poisson ratio on curvature of σ-ε law. 2. A truss finite element has been used in the nonlinear static and dynamic analysis of plane RC frames;it has been compared with test results and describes, in a simple way, the formation of plastic hinges. 3. Thanks to the very simple geometry of a truss, the equilibrium equations can be easily written and the stiffness matrix can be easily updated, both with respect to the deformed truss, within each step of a static incremental loading or within each time step of a dynamic analysis, so that to take into account geometric nonlinearities. So the confinement of a RC column is interpreted as a structural stability effect of concrete. And a significant role of the transverse reinforcement is revealed, that of preventing, by its close spacing and sufficient amount, the buckling of inner longitudinal concrete struts, which would lead to a global instability of the RC column. 4. The proposed truss model is statically indeterminate, so it exhibits some features, which are not met by the “strut-and-tie” model.
基金financially supported by Natural Science Foundation of China(No.81871411)National Key R&D Program of China(2018YFC0910601)+1 种基金Youth Innovation Promotion Association Foundation of CAS(2017340)The Science&Technology Bureau of Ningbo City(2015B11002).
文摘Zeolitic imidazolate frameworks(ZIFs)as smart drug delivery systems with microenvironment-triggered release have attracted much attention for tumor therapy.However,the exploration of ZIFs in biomedicine still encounters many issues,such as inconvenient surface modification,fast drug release during blood circulation,undesired damage to major organs,and severe in vivo toxicity.To address the above issues,we developed an Mn-ZIF-90 nanosystem functionalized with an originally designed active-targeting and pH-responsive magnetic resonance imaging(MRI)Y1 receptor ligand[Asn28,Pro30,Trp32]-NPY(25-36)for imaging-guided tumor therapy.After Y1 receptor ligand modification,the Mn-ZIF-90 nanosystem exhibited high drug loading,better blood circulation stability,and dual breast cancer cell membrane and mitochondria targetability,further favoring specific microenvironment-triggered tumor therapy.Meanwhile,this nanosystem showed promising T1-weighted magnetic resonance imaging contrast in vivo in the tumor sites.Especially,this nanosystem with fast clean-up had almost no obvious toxicity and no damage occurred to the major organs in mice.Therefore,this nanosystem shows potential for use in imaging-guided tumor therapy.
文摘Changes and reconfiguration of information systems(ISs)are two kernel concepts of rapidil reconfigurable in-formation system(RRIS).It is the abilitise to evolve with changes that make RRIS superior to the traditional ISs.Hierarchical architecture of RRIS is put forward.And then a component-based framework of RRIS is discussed including its building and designing in detail.
文摘A novel coordination polymer of [Ca(2-OPA)2(H2O)2]n (2-OPA-=2-oxo-1(4H)-pyridineacetate anion) was synthesized and characterized by elemental analysis, IR, TG and single crystal X-ray diffraction. The title complex crystallizes in orthorhombic with space group Pna21, a=0.799 96(16) nm, b=0.823 77(16) nm, c=2.415 3(5) nm, V=1.591 6(6) nm3, Z=4, R=0.030 3, wR=0.070 0. The Ca atom is eight-coordinated by six O atoms of four 2-OPA- ligands and two water molecules, and displays a dodecahedron coordination geometry. Each 2-OPA- ligand bridges two adjacent Ca atoms, forming a infinite chain along the a direction. The Ca...Ca distance is 0.4102 2(8)nm. A two-dimensional supramolecular framework is further constructed by the hydrogen bonds and the weak π-π interactions. The results of TG analysis show the chain structure of the title complex was stable under 297.5 ℃. CCDC: 251669.
文摘In this paper, a new class of over-relaxed proximal point algorithms for solving nonlinear operator equations with (A,η,m)-monotonicity framework in Hilbert spaces is introduced and studied. Further, by using the generalized resolvent operator technique associated with the (A,η,m)-monotone operators, the approximation solvability of the operator equation problems and the convergence of iterative sequences generated by the algorithm are discussed. Our results improve and generalize the corresponding results in the literature.
文摘The Paris Agreement proposed to keep the increase in global average temperature to well below 2 ℃ abovepre-industrial levels and to pursue efforts to limit the temperature increase to 1.5 ℃ above pre-industriallevels. It was thus the first international treaty to endow the 2 ℃ global temperature target with legal effect.The qualitative expression of the ultimate objective in Article 2 of the United Nations Framework Conventionon Climate Change （UNFCCC） has now evolved into the numerical temperature rise target in Article 2 of theParis Agreement. Starting with the Second Assessment Report （SAR） of the Intergovernmental Panel on Cli-mate Change （IPCC）, an important task for subsequent assessments has been to provide scientific informa-tion to help determine the quantified long-term goal for UNFCCC negotiation. However, due to involvementin the value judgment within the scope of non-scientific assessment, the IPCC has never scientifically af-firmed the unacceptable extent of global temperature rise. The setting of the long-term goal for addressingclimate change has been a long process, and the 2 ℃ global temperature target is the political consensuson the basis of scientific assessment. This article analyzes the evolution of the long-term global goal foraddressing climate change and its impact on scientific assessment, negotiation processes, and global low-carbon development, from aspects of the origin of the target, the series of assessments carried out by the 1PCCfocusing on Article 2 of the UNFCCC, and the promotion of the global temperature goal at the political level.
文摘The tremendous growth of the cloud computing environments requires new architecture for security services. Cloud computing is the utilization of many servers/data centers or cloud data storages (CDSs) housed in many different locations and interconnected by high speed networks. CDS, like any other emerging technology, is experiencing growing pains. It is immature, it is fragmented and it lacks standardization. Although security issues are delaying its fast adoption, cloud computing is an unstoppable force and we need to provide security mechanisms to ensure its secure adoption. In this paper a comprehensive security framework based on Multi-Agent System (MAS) architecture for CDS to facilitate confidentiality, correctness assurance, availability and integrity of users' data in the cloud is proposed. Our security framework consists of two main layers as agent layer and CDS layer. Our propose MAS architecture includes main five types of agents: Cloud Service Provider Agent (CSPA), Cloud Data Confidentiality Agent (CDConA), Cloud Data Correctness Agent (CDCorA), Cloud Data Availability Agent (CDAA) and Cloud Data Integrity Agent (CDIA). In order to verify our proposed security framework based on MAS architecture, pilot study is conducted using a questionnaire survey. Rasch Methodology is used to analyze the pilot data. Item reliability is found to be poor and a few respondents and items are identified as misfits with distorted measurements. As a result, some problematic questions are revised and some predictably easy questions are excluded from the questionnaire. A prototype of the system is implemented using Java. To simulate the agents, oracle database packages and triggers are used to implement agent functions and oracle jobs are utilized to create agents.
文摘The Sun et al's training program for clinical research nurses(CRNs)in the World Journal of Clinical Cases is a comprehensive and scientific approach.It includes structured frameworks for CRN training,aiming to improve CRN competency.This program emphasizes practical abilities,updates training content,and improves evaluation methods.The cultivation of CRN talents focuses on enhancing the training system,establishing a multifaceted evaluation framework,and continuously refining the training programs.Regular feedback and evalua-tion are essential to improve CRNs'competency in practical settings.
基金Hebei University of Technology and Tshwane University of Technology for their support and financial contributionpartly supported by the Higher Educational Reform Fund of Hebei Province,People’s Republic of China(No.2017GJJG022).
文摘Higher education internationalization(HEI)has become an important priority for global decision makers and education providers.Persuaded by globalization,HEI is a political strategy and economic prospect for countries,governments,and universities to position themselves in global markets.The purpose of this paper is to provide a methodological pathway to develop a dynamic,reformed South African HEI framework based on the transformative drive(i.e.,adjustment of change,learning,shared knowledge,internationalization,globalization an institutionalized memory)of HEI in China.The interpretivist paradigm constitutes the basic research approach.Quantitative and qualitative data will be collected,analyzed,and integrated using a multiphase mixed methods approach.This approach consists of three phases including content analysis(Phase I),in-depth interviews(Phase II),and surveys(Phase III),which answers the focal research question.The significance of this research includes creating a better understanding of South African higher education(HE)policy issues from a transformational perspective,contributing to theory on how internationalization affects HE’s position in economic and social development and broadening knowledge and understanding of the unique circumstances and challenges of HEI in developing countries,particularly in countries seeking to position themselves in the globalized knowledge economy.
