Observation on Therapeutic Effect of Lotus Needle Cupping Therapy for Removing Blood Stasis in Zhuang Medicine on PHN and Its Influ-ence on Inflammatory Mediators

[Objectives]To observe the clinical effect of the lotus needle cupping therapy for removing blood stasis in Zhuang medicine in treating PHNand its influence on inflammatory factors.[Methods]96 patients with PHN were randomly divided into three groups:lotus nee-dle cupping therapy group,TCM surrounding acupuncture group and gabapentin group.Venous blood and acupoint blood were collected at 0,21 and 42 d of treatment,and the expression levels of 5-HT,SP and CGRPinflammatory mediators were detected before and after treatment.The changes of VAS scores before,during and after treatment and the clinical efficacy were observed.[Results]The total effective rate of the lotus needle cupping group was 87.50%,which was better than that of the TCM acupuncture group(81.25%)and the gabapentin group(62.50%);after treatment,the VAS scores and the expression of inflammatory mediators in the three groups of patients were lower than those before treatment,and the decrease was more significant in the treatment group(P<0.05).[Conclusions]The lotus needle cupping therapy for removing blood stasis in Zhuang medicine is effective in treating PHN,and its mechanism is to reduce the release of inflammatory media-tors,reduce hyperalgesia,relieve pain and improve the quality of life of patients.

Cellular manufacturing layout on adding/removing machines

In order to rapidly respond to the complex and mutational market, a new facility layout plan based on cellular manufacturing is proposed, which gives consideration to high efficiency and flexibility. The plan designs two phases of integrated cell layout, i.e., cell construction and cell system layout, on the condition of adding/removing machines. First, in view of the costs of logics and machine-relocation, the cell construction based on the alternative processing routes and intra-cell layout are integrated as a whole, which achieves cell formation, process planning and the intra-cell layout in a single step. Secondly, an approach of a continuous optimized multi-line layout for solving the cell system layout problem is proposed, which eliminates the coupling relationship from the machine-relocation and realizes an integrated design of the two phases of the cell layout. An application based on real factory data is optimally solved by the Matlab 7.0 software to validate and verify the models.

Thermodynamics of removing impurities from crude lead by vacuum distillation refining

A novel technique was developed to remove impurities from crude lead by vacuum distillation.The thermodynamics on vacuum distillation refining process of crude lead was studied by means of saturated vapor pressure of main components of crude lead,separation coefficients and vapor-liquid equilibrium composition of Pb-i（i stands for an impurity） system at different temperatures.The behaviors of impurities in the vacuum distillation refining process were investigated.The results show that the vacuum distillation should be taken to obtain lead from crude lead,in which Zn,As and partial Sb are volatilized at lower temperature of 923-1023 K.Lead is distilled from the residue containing Cu,Sn,Ag and Bi at higher temperature of 1323-1423 K,but the impurity Bi is also volatilized along with lead and cannot be separated from lead.

Isolation of Denitrifying Bacteria in Sea Sediment and Simulated Experiment of Removing Nitrate-N from Seawater

The objective of this research was to isolate denitrifying bacteria from sea sediment and simulate the removal efficiency of nitrate-N by denitrifying bacteria from seawater. The result showed that the isolated denitrifying bacteria could effectively remove nitrate-N from seawater. About 90 % of nitrate-N was removed by denitrifying bacteria from seawater within a week in the simulated experiment I （the initial concentration of nitrate-N was 100 mg/L）. The removal efficiency of nitrate-N reached about 70 % within one day in the simulated experiment Ⅱ （initial concentration of nitrate-N was 1 mg/L）. The final removal efficiency was about 98 % and 85 % in the simulated experiments Ⅰ and Ⅱ, respectively. It was found that there was positive correlation between the concentration of nitrate-N and the number of denitrifying bacteria in seawater. Lots of denitrifying bacteria would disappear and the seawater would become transparent once the process of bioremediation was completed.

Identification and Metabolic Mechanism of Non-fermentative Short-cut Denitrifying Phosphorus-removing Bacteria

To investigate the characteristics and metabolic mechanism of short-cut denitrifying phospho- rus-removing bacteria （SDPB） that are capable of enhanced biological phosphorus removal （EBPR） using nitrite as an electron acceptor, an aerobic/anoxic sequencing batch reactor was operated under three phases. An SDPB-strain YC was screened after the sludge enrichment and was identified by morphological, physiological, biochemical properties and 16S rDNA gene sequence analysis. Denitrifying phosphorus-removing experiments were conducted to study anaerobic and anoxic metabolic mechanisms by analyzing the changes of chemical oxygen demand （COD）, phosphate, nitrite, poly-fl-hydroxybutyrate （PHB）, and glycogen. The results show that strain YC is a non-fermentative SDPB similar to Paracoccus denitrificans. As a kind of non-fermentative bacteria, the energy of strain YC was mainly generated from phosphorus release （96.2%） under anaerobic conditions with 0.32 mg P per mg synthesized PHB. Under anoxic conditions, strain YC accumulated 0.45 mg P per mg degraded PHB, which produced most of energy for phosphate accumulation （91.3%） and a little for glycogen synthesis （8.7%）. This metabolic mechanism of strain YC is different from that of traditional phosphorus-accumulating organisms （PAOs）. It is also found that PHB, a kind of intracellular polymer, plays a very important role in denitrifying and accumulating phosphorus by supplying sufficient energy for phosphorous accumulation and carbon sources for denitrification. Therefore, monitoring AP/APHB and ANO2 -N/APHB is more necessary than monitoring AP/ACOD, ANO2 -N/ACOD, or AP / ANO2 -N.

The anti-correlation method for removing harmonic distortion in vibroseis slip-sweep data

The slip-sweep technique is one of the high-efficiency, high-fidelity, and environmental vibroseis seismic prospecting techniques which consists of a vibrator group sweeping without waiting for the previous group＇s sweep to terminate. The cycle time can be reduced drastically and hence the production efficiency can be increased significantly but harmonic distortion of one sweep will leak into the record of the other sweep. In this paper, we propose an anti-correlation method for removing harmonic distortion in vibroseis data. This method is based on decomposition of the ground force signal into fundamental and harmonic components. Then the corresponding anti-correlation operator can be computed to estimate the energy of each harmonic after correlating the vibroseis data with the corresponding harmonic component. Finally, the vibroseis harmonic noise to be removed can be obtained by subtracting the extracted harmonic noise from the traces of the previous group＇s sweep. The advantage of the proposed method is that it can process both uncorrelated and correlated vibroseis seismic data. Moreover, the algorithm is simple, stable, and computationally fast. Especially, the significant contribution of this method is a considerable reduction in the harmonic without any alteration of the desired signals. The method was tested on both synthetic and field data sets to validate the good harmonic noise suppression results.

Role of Removing Stasis and Reducing Heat Formula in Clearance of Proximal Ureteral Calculi after Ureteroscopic Ho:YAG Laser Lithotripsy: A Prospective Randomized Study

Objective To prospectively evaluate the efficacy of Removing Stasis and Reducing Heat Formula in accelerating calculus clearance and improving lower urinary tract symptoms of patients with proximal ureteral calculi after ureteroscopic Ho:YAG laser lithotripsy. Methods A total of 138 patients with proximal ureteral calculi underwent ureteroscopic Ho:YAG laser lithotripsy by a single endocrinologist. Stone size varied from 10 to 15 mm. After operation, the patients were randomly divided into three groups: the control group(group A), tamsulosin group(group B), and Removing Stasis and Reducing Heat Formula group(group C). The treatment lasted for 4 weeks or until stone clearance. The primary and secondary outcomes of the three groups at follow-up were assessed. Results Of the 131 patients available for follow-up, 44 cases were in the group A, 45 in the group B, and 42 in the group C, respectively. The stone free rate at 2 weeks in the groups B and C were significantly higher than that in the group A(95.56%, 97.62% vs. 79.55%; all P<0.05). The ureteral colic rate and mean time of fragment expulsion were significantly reduced in the groups B(4.44% and 7.86±4.99 days) and C(2.43% and 6.76±4.37 days) compared with the group A(22.73% and 11.54±9.89 days, all P<0.05). On the day of double-J ureteric stent removal, the group C differed significantly from the group A in the total International Prostate Symptom Score, irritative subscore, obstructive subscore, and quality of life score(all P<0.05). Conclusion Removing Stasis and Reducing Heat Formula in the medical expulsive therapy might be an effective modality for patients with calculus in the proximal uretera after ureteroscopic Ho:YAG laser lithotripsy.

Study on Method of Removing Stripe Noise in CBERS-02 Image

Based on the project of land macroscopical monitoring by CBERS,a remote sensing image of Arongqi in Inner Mongolia was studied by different methods such as histogram matching,principal component analysis,moment matching,low-pass filter and wavelet transform.A qualitative analysis and quantitative assessment was also carried out.The results showed that wavelet transform could effectively remove stripe noise,and also kept its advantages in the details.Moment matching had a better strip removal,but it changed features in its spectrum easily and it was not fit for CBERS-02 image processing.Principal component analysis could not remove stripe noise,but also strengthened it in a certain extent.

Operation of three parallel AN/AO processes to enrich denitrifying phosphorus removing bacteria for low strength wastewater treatment

Three parallel anaerobic-anoxic/anaerobic-aerobic （AN/AO） processes were developed to enrich denitrifying phosphorus removal bacteria （DPB） for low strength wastewater treatment. The main body of the parallel AN/AO process consists of an AN （anaerobic-anoxic） process and an AO （anaerobic-aerobic） process. In the AO process, the common phosphorus accumulating organisms （PAOs） was dominate, while in the AN process, DPB was dominate, The volume of anaerobic zone（Vana）：anoxie zone（Vano） ： aerobic zone （Vaer） for the parallel AN/AO process is 1：1：1 in contrast with a Vana：Vaer and Vano：Vaer of 1：2 and 1：4 for a traditional biological nutrient removal process （BNR）. Process 3 excels in the 3 processes on the basis of COD, TN and TP removal. For 4 month operation, the effluent COD concentration of process 3 did not exceed 60 mg/L; the effluent TN concentration of process 3 was lower than 15 mg/L; and the effluent TP concentration of process 3 was lower than 1 mg/L.

Simultaneous removing SO_2 and NO by a new system containing cobalt complex

Absorption and catalytic oxidation of nitric oxide can be achieved by using cobalt（Ⅲ） ethylenediamine （Co（en）3^3＋. When simultaneous absorbing SO2 and NO, the precipitation of Co2（SO3）3 will be yielded and the NO removal will be decreased. A new catalyst system using Co（en）3^3＋ coupled with urea has been developed to simultaneous remove NO and SO2 in the flue gas. NO is absorbed and catalytically oxidized to nitrite and nitrate by Co（en）3^3＋. The dissolved oxygen in scrubbing solution from the feed stream acts as oxidant. Urea restrains the precipitation of Co2（SO3）3 by oxidizing SO3^2-to SO4^2- as COSO4 is more soluble in water. The experimental results proved that nearly all SO3^2- can be oxidized to SO4^2- and the high NO and SO2 removal could be obtained with the new system. The NO removal is influenced by gas flow rate, the concentration of Co（en）3^3＋ and urea in the absorption solution, the temperature of the scrubbing solution and the content of oxygen in the flue gas. The low gas flow rate is favorable to increase the NO removal. The experiments proved that the NO removal could be maintained at more than 95% by the system of 0.02 mol/L Co（en）3^3＋ and 1% urea at 50℃ with 10% O2 in the flue gas.

INVESTIGATION OF PARAMETERS OF NONWOVEN FILTER USED IN WHITE CELLS REMOVING

This paper is concerned with the relation between the parameters of nonwoven filter and removing of white cells. Melt-blown polypropylene nonwovens are used as filtration materials of white cells filter. According to the combination of different fiber diameter, different product density and different weight, optimized combination of parameters of nonwoven filter with more effective removing of white cells is obtained. The result is that removing of white cells is 96.90 percent; recovery of red cells is 92.27 percent.

Removing Iron by Magnetic Separation from a Potash Feldspar Ore

A new permanent magnetic separator was introduced to treat the ores with the characteristics of weak magnetic iron minerals and in a fine size range. The new machine was applied to the iron removal from potash feldspar. The effects of the magnetic field intensity, pulp density and grinding fineness on the iron removal were investigated. The optimized operation parameters were achieved and listed as follows： the -0.074 mm content is 85%, the pulp density is 45% and the magnetic field strength is 2T. A close test of middles regrinding was also carried out to improve concentrate yield. The data show that the grade of TFe（total iron） in potash feldspar product decreased from 1.31% to 0.21% and the concentrate yield reached 85.32%. All the results indicated that the traditonal high-intensity electromagnetic separators can be betterly substituted by the new permanent magnetic separator. This study may provide the theoretical evidence for iron removal from potash feldspar.

Isogeometric Analysis and Shape Optimization of Holed Structures via the Patch Removing Technique

In this study,a patch removing based Isogeometric analysis(PR-IGA)method is proposed to conduct the holed structural analysis with only one parametric domain,in which there are also no trimmed elements.The theoretical foundation of this novel patch removing approach is that any holed structure can be obtained by removing sub-patches(i.e.,the holes)from an intact base patch.Since the parametric domains of these patches are all meshed by rectangular grids,the elements in the resulted holed structural parametric domain could all be untrimmed rectangles under certain mapping conditions.To achieve the special condition,a systematic technique consisting of T-spline local refinement and control points substitution/adjustment is provided.Due to the intactness of parametric elements,the analysis procedure of holed structures based on the proposed PRIGA is quite simplified and efficient compared to traditional multi-patch and trimming schemes.Moreover,after the deduction of analytical sensitivities related to structural mass and mechanical responses,the PR-IGA is directly employed in the holed structural shape optimization to successfully eliminate the need for model transformation during modeling,analysis and optimization processes.Numerical examples involving analysis and shape optimization of complex holed structures are presented to demonstrate the effectiveness of the proposed method.

Comparison of mechanisms and efficacies of five formulas for improving blood circulation and removing blood stasis

Objective This study aimed to compare the mechanisms and efficacies of five formulas that improve blood circulation and remove blood stasis.Methods(1)A network pharmacology method was used to determine the targets of five formulas that promote circulation and remove blood stasis.Compounds of the five formulas,namely Danshen Yin(丹参饮,DSY),Huoluo Xiaoling Dan(活络效灵丹,HLXLD),Shixiao San(失笑散,SXS),Taohong Siwu Tang(桃红四物汤,THSWT),and Xuefu Zhuyu Tang(血府逐瘀汤,XFZYT),were retrieved from the Traditonal Chinese Medicine System Pharmacology Database(TCMSP),the Shanghai Institute of Organic Chemistry of CAS,and the TCM Integrated Database.Drug target network was constructed by searching the Swiss Target Prediction database and the STITCH database.The target network of stasis was extracted from the PharmGKB database,the Online Mendelian Inheritance in Man(OMIM)database,the Genetic Association Database(GAD),and the Therapeutic Target Database(TTD).Candidate targets were determined using protein-protein interaction(PPI)network extension and topology selection.Thereafter,Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analysis was used to determine the differentiation of the mechanism of the five formulas.(2)Animal experiments were conducted to explore the efficacies of the five formulas in treating blood stasis.Seventy New Zealand rabbits were exposed to high-fat feeding+epinephrine injection to construct a blood stasis syndrome model.The rabbits were evenly divided into control,model,DSY,HLXLD,SXS,THSWT,and XFZYT groups.The latter five groups were orally administered the corresponding formulas[DSY:3.92 g/(kg·d),XFZYT:7.10 g/(kg·d),SXS:1.12 g/(kg·d),HLXLD:5.60 g/(kg·d),THSWT:4.48 g/(kg·d)].Serum lipid and blood rheology were analyzed,and pathology slices were observed.Results(1)A total of 269,358,288,370,and 376 candidate targets of DSY,HLXLD,SXS,THSWT,and XFZYT were obtained among which were 232 shared candidate targets.Fluid shear stress and atherosclerosis were the biological processes common to the five formulas.HLXLD,SXS,DSY,and THSWT regulated lipolysis in adipocytes,and XFZYT,HLXLD,SXS,and THSWT regulated the AGE-RAGE signaling pathway and complement and coagulation cascades.HLXLD,SXS,and XFZYT regulated the HIF-1 signaling pathway,DSY regulated the cGMP-PKG signaling pathway,HLXLD reduced platelet activation,SXS regulated the calcium signaling pathway,and XFZYT regulated the PPAR signaling pathway.(2)In the animal experiments,the values of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL),high density lipoprotein cholesterol(HDL),TC/HDL,and TG/HDL in each group decreased,among which the ones seen in XFZYT,HLXLD,and SXS groups were statistically significant(P<0.05).XFZYT presented the best effect,followed by HLXLD and SXS.XFZYT and HLXLD decreased apolipoprotein B100(apoB100)and increased apolipoprotein A1/apoB100(P<0.05).XFZYT decreased all the values of hematocrit(HCT),plasma viscosity,whole blood viscosity(WBV);HLXLD and SXS affected HCT;and DSY and THSWT regulated WBV(P<0.05).All the five formulas decreased the values of optical density and area of plaque,among which XFZYT and HLXLD showed statistical significance(P<0.05).Conclusion Adjusting fluid shear stress and alleviating the injury of endothelial cells might be the common mechanisms by which the five formulas promote blood circulation and remove blood stasis.Different formulas also have unique targets,which may provide guidance for clinical drug selection.By regulating different indices,the five formulas can regulate blood lipid and hemorheology,improve the state of blood stasis,and decrease the degree of aortic plaque in the blood stasis model rabbits.XFZYT and HLXLD had higher efficacies than DSY,THSWT,and SXS.

Past,present and future of preserving and restoring function in the visual system:removing galectin-3 as a promising treatment

Great advances in retinal ganglion cells survival（RGCs）,optic nerve preservation and regeneration have been made in the past 15years.Nowadays,we know that RGCs are capable of regenerating the full length of the optic nerve,cross the chiasm,enter the brain and reinnervate visual targets.

TREATMENT OF 53 CASES OF ECTOPIC PREGNANCYWITH THE AGENTS FOR PROMOTING BLOODCIRCULATION AND REMOVING BLOOD STASIS

The non-operative treatment of ectopicpregnancy with traditional Chinese medicine(TCM)combined with western medicine hasbeen widely used clinically.The therapeuticresults are satisfactory.Although there areminor variations among different medical institutions,the general principles of thetherapy are the same,i.e.promoting bloodcirculation and removing blood stasis.

Removing Impurity of cBN Crystal Prepared at High Pressure and High Temperature

The black cubic boron nitride(cBN)single crystal is synthesized by using hBN-LiH and hBN-Li_(3)N-B as the raw materials at high temperature and high pressure(HTHP).The colors of the cBN crystal synthesized in an hBN-Li_(3)N-B system vary from transparent yellow,half-transparent and then opaque black with the increasing B content in the raw materials.It is worth noting that a trigonal shadow is presented at the center of the cBN crystal synthesized in the hBN-Li_(3)N-B system but can not be found in the hBN-LiH system.Analyzing the Raman spectrum,we find that the darkening and the trigonal shadow in the cBN crystal may be due to the presence of excess B atoms.The above-mentioned phenomenon can be determined by removing impurity capacity and growth environment of the cBN crystal.

Guard Catalyst for Removing Carbonyl Iron/Carbonyl Nickel during Methanol Synthesis Developed by SINOPEC Nanjing Chemical Research Institute Has as HPassed Appraisal

On December 28,2020 the project on R&D of guard catalyst for removing carbonyl iron/carbonyl nickel undertaken by the SINOPEC Nanjing Chemical Research Institute(NCRI)has passed the research achievements appraisal organized by the Sinopec Science and Technology Division.The experts attending the appraisal meeting have suggested speeding up the commercial application tests as soon as possible.

Effect of Chinese Herbs for Activating Blood Circulation,Removing Stasis and Supplementing Qi on the Circulating Endothelial Cells in Patients with Unstable Angina Pectoris

Objective: To observe the effect and clinical significance of circulating endothelial cells (CEC) in the pathogenesis of coronary heart disease with unstable angina pectoris (CHD-UAP), and to explore the protective effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi (CH) on CHD-UAP patient's CEC. Methods: Sixty patients with diagnosis of CHD-UAP confirmed and differentiated to be Qi-deficiency and blood stasis by TCM were randomly divided into two groups and treated, on the basis of Western drug-therapy, with Tongxinluo capsule (通心络胶囊, TXL) and Huoxue Tongmai capsule (活血通脉胶囊, HXTM) respectively by way of oral taking three times a day, 3 capsules every time, with 1 month as one therapeutic course. The number of CEC in patients' blood circulation was counted before and after treatment. Besides, the number of CEC in 30 healthy persons was also counted for control. Results: The number of CEC in CHD-UAP patients was significantly higher than that in the healthy persons (P<0.01). After the patients were treated with CH, either TXL or HXTM, it significantly decreased (P<0.01)with insignificant difference between the two treated groups. Conclusion: CEC in CHD-UAP patients is severely damaged and endothelial function in disorder, Chinese herbs have protective effect on patients' CEC.

A Kind of Lean Approach for Removing Wastes From Non-Manufacturing Process With Various Facilities

It is important to identify and remove the wastes not only from manufacturing process, but also from nonmanufacturing process. In the last several decades, significant research achievements and practice benefits have been achieved about removing wastes from manufacturing process. Since the1990 s, some researchers and lean practitioners have paid more attention to removing waste from non-manufacturing process.Based on the authors' research work and industrial practice, the paper introduces a kind of lean approach for removing waste from non-manufacturing process. In its case study, the order handling process in a value chain is described with respect to a factory and its downstream distribution centers(DCs). The paper proposes a lean approach solution for creating the improved order handling process, and analyze how great improvements in performance can be achieved. As a result, the significant achievement has created a win-win scenario for both the nonmanufacturing process in a factory and non-manufacturing facilities(like DCs) across the value chain. It demonstrates that improvements have been made by removing waste from the non-manufacturing process that takes place within a factory as well as with external participants through the whole value chain. Likewise, the proposed lean approach has helped the case companies to achieve greater levels of efficiency and more benefits. Finally, some conclusions are drawn.