目的：观察改良 Rex 手术治疗儿童肝外型门静脉梗阻的临床效果。方法肝外型门静脉梗阻并门脉高压患儿6例，均采用改良 Rex 手术治疗，术中利用肝静脉属支为肝内门静脉矢状部搭桥。结果6例均成功实施手术，分流术前测肠系膜下静脉压力为2...目的：观察改良 Rex 手术治疗儿童肝外型门静脉梗阻的临床效果。方法肝外型门静脉梗阻并门脉高压患儿6例，均采用改良 Rex 手术治疗，术中利用肝静脉属支为肝内门静脉矢状部搭桥。结果6例均成功实施手术，分流术前测肠系膜下静脉压力为27．5～46．0 cm H2 O，分流术后降为16．0～28．0 cm H2 O，分流前后相比，P ＜0．01。术后血管造影检查显示分流血管通畅无狭窄，患儿各项肝功能指标正常。结论改良 Rex 分流术治疗儿童肝外型门静脉梗阻效果良好。展开更多
目的总结Rex分流联合断流、脾动脉结扎术治疗小儿门静脉海绵样变的经验与疗效。方法回顾性分析2012年8月至2019年7月在安徽省儿童医院行Rex分流联合断流、脾动脉结扎术治疗的16例门静脉海绵样变、门静脉高压症患儿临床资料及随访结果。...目的总结Rex分流联合断流、脾动脉结扎术治疗小儿门静脉海绵样变的经验与疗效。方法回顾性分析2012年8月至2019年7月在安徽省儿童医院行Rex分流联合断流、脾动脉结扎术治疗的16例门静脉海绵样变、门静脉高压症患儿临床资料及随访结果。结果15例成功手术,分流前门静脉测压28.3~45.8 cm H 2O,平均(32.6±5.4)cm H 2O,分流后显著下降为17.2~27.8 cm H 2O,平均(23.4±3.7)cmH 2O,分流前后门静脉压力差异有统计学意义(P<0.01)。术后均恢复出院。1例术中吻合血管不通畅加行Warren术,术后脾肾静脉吻合口血栓形成,介入治疗效果不显著,自动出院后死亡。成功手术的15例患儿术后随访6个月至6年,平均随访31.5个月,3例术后有消化道出血复发,药物止血均较易控制,其中2例均复发1次,1例复发2次后未再出血,但出现脾大、脾功能亢进,术后5年行脾切除术。15例均生长发育良好。结论Rex分流联合断流、脾动脉结扎术治疗小儿门静脉海绵样变所致门静脉高压症效果确切。展开更多
[Objective]The paper was to analyze the pathogenesis of Escherichia coli O123 from rex rabbit. [Method]E. coli O123 isolated from rabbit liver with diarrhea symptom in scale rex rabbit farm was intraperitoneally injec...[Objective]The paper was to analyze the pathogenesis of Escherichia coli O123 from rex rabbit. [Method]E. coli O123 isolated from rabbit liver with diarrhea symptom in scale rex rabbit farm was intraperitoneally injected into 18- 22 g Kunming mice,and its pathogenicity was determined by clinical symptoms and pathological examination. [Result]When the inoculation concentration was about 8. 5 × 107 CFU /mL,Kunming mice appeared the clinical symptoms of drooping spirit,diarrhea and gathering,and the mortality reached 50%. Anatomical examination found that intestinal wall was thinning and intestinal mucosa was bleeding. [Conclusion]E. coli from rex rabbit has strong pathogenicity,and establishing animal model with Kunming mice to study its pathogenesis is of great reference significance for diagnosis and prevention of E. coli disease of rex rabbit.展开更多
Oedipus Rex,which was created by Sophocles,is a famous tragedy.Although Oedipus in this play tries very hard to find his origin and self-identity,it is not necessarily the reason for his downfall.The real reason he wa...Oedipus Rex,which was created by Sophocles,is a famous tragedy.Although Oedipus in this play tries very hard to find his origin and self-identity,it is not necessarily the reason for his downfall.The real reason he was so tragic is that he had no control of himself,making things worse by his arrogance,ostentation and fierce-temptation and therefore inevitably fulfilled his fate no matter how hard he tries to escape.展开更多
Loco-regional recurrence after potentially curative resection remains a problem in hilar cholangiocarcinoma. Hilar dissection risks local spillage of tumor cells leading to suboptimal disease free survival. We have de...Loco-regional recurrence after potentially curative resection remains a problem in hilar cholangiocarcinoma. Hilar dissection risks local spillage of tumor cells leading to suboptimal disease free survival. We have developed a new technique of radical resection for hilar cholangiocarcinoma based on the distinctive anatomy of the Rex recess of the liver, which has been assessed in two patients with locally advanced hilar cholangiocarcinoma. This technique included a right hepatectomy with en-bloc resection of the hepatoduodenal ligament and portal venous reconstruction to the left portal vein at the Rex recess. Both patients had R0 resection and have been disease-free for 26 and 38 months, respectively.展开更多
BACKGROUND The Rex shunt was widely used as the preferred surgical approach for cavernous transformation of the portal vein(CTPV)in children that creates a bypass between the superior mesenteric vein and the intrahepa...BACKGROUND The Rex shunt was widely used as the preferred surgical approach for cavernous transformation of the portal vein(CTPV)in children that creates a bypass between the superior mesenteric vein and the intrahepatic left portal vein(LPV).This procedure can relieve portal hypertension and restore physiological hepatopetal flow.However,the modified procedure is technically demanding because it is difficult to make an end-to-end anastomosis of a bypass to a hypoplastic LPV.Many studies reported using a recanalized umbilical vein as a conduit to resolve this problem.However,the feasibility of umbilical vein recanalization for a Rex shunt has not been fully investigated.AIM To investigate the efficacy of a recanalized umbilical vein as a conduit for a Rex shunt on CTPV in children by ultrasonography.METHODS A total of 47 children who were diagnosed with CTPV with prehepatic portal hypertension in the Second Hospital,Cheeloo College of Medicine,Shandong University,were enrolled in this study.Fifteen children received a recanalized umbilical vein as a conduit for a Rex shunt surgery and were enrolled in group I.Thirty-two children received the classic Rex shunt surgery and were enrolled in group II.The sonographic features of the two groups related to intraoperative and postoperative variation in terms of bypass vessel and the LPV were compared.RESULTS The patency rate of group I(60.0%,9/15)was significantly lower than that of group II(87.5%,28/32)7 d after(on the 8th d)operation(P<0.05).After clinical anticoagulation treatment for 3 mo,there was no significant difference in the patency rate between group I(86.7%,13/15)and group II(90.6%,29/32)(P>0.05).Moreover,3 mo after(at the beginning of the 4th mo)surgery,the inner diameter significantly widened and flow velocity notably increased for the bypass vessels and the sagittal part of the LPV compared to intraoperative values in both shunt groups(P<0.05).However,there was no significant difference between the two surgical groups 3 mo after surgery(P>0.05).CONCLUSION For children with hypoplastic LPV in the Rex recessus,using a recanalized umbilical vein as a conduit for a Rex shunt may be an effective procedure for CTPV treatment.展开更多
[ Objective] To study the effects of diets with different com-to-soybean ratios on production performance of lactational Rex rabbits and select the best feed formula. [Method] A total of 80 lactational healthy Rex rab...[ Objective] To study the effects of diets with different com-to-soybean ratios on production performance of lactational Rex rabbits and select the best feed formula. [Method] A total of 80 lactational healthy Rex rabbits （similar age, body weight and delivery time） were randomly divided into five groups, 16 in each group. The Rex rabbits in group I were fed with corn-based meal diet, group II with soybean-based meal diet, group III with the developed corn-soybean meal diet, group IV with corn-soybean meal free diet, and group CK with conventional corn-soybean meal diet. During the lactation period, the changes in the lactation performance, growth rate of baby rabbits, weight and feed costs were observed. [ Result] The lactation performance of mother rabbits and the growth rate of baby rabbits in the experimental groups were similar to that in the control group. The weaning survival rate of the group III was the highest, but it was not significantly higher than that of the control group. The weaning survival rate of the other three groups was lower than that of the control group （P〈0.05）. The weight loss of mother rabbits in the group I, II and III was not significantly different from that of the control group, but the weight loss of the group IV was higher than that of the control group （ P 〈 0.01 ）. [ Conclusion] Diets with appropriate corn-to-soybean ratios not only reduce feed costs but also give the best feeding effects.展开更多
文摘目的：观察改良 Rex 手术治疗儿童肝外型门静脉梗阻的临床效果。方法肝外型门静脉梗阻并门脉高压患儿6例，均采用改良 Rex 手术治疗，术中利用肝静脉属支为肝内门静脉矢状部搭桥。结果6例均成功实施手术，分流术前测肠系膜下静脉压力为27．5～46．0 cm H2 O，分流术后降为16．0～28．0 cm H2 O，分流前后相比，P ＜0．01。术后血管造影检查显示分流血管通畅无狭窄，患儿各项肝功能指标正常。结论改良 Rex 分流术治疗儿童肝外型门静脉梗阻效果良好。
文摘目的总结Rex分流联合断流、脾动脉结扎术治疗小儿门静脉海绵样变的经验与疗效。方法回顾性分析2012年8月至2019年7月在安徽省儿童医院行Rex分流联合断流、脾动脉结扎术治疗的16例门静脉海绵样变、门静脉高压症患儿临床资料及随访结果。结果15例成功手术,分流前门静脉测压28.3~45.8 cm H 2O,平均(32.6±5.4)cm H 2O,分流后显著下降为17.2~27.8 cm H 2O,平均(23.4±3.7)cmH 2O,分流前后门静脉压力差异有统计学意义(P<0.01)。术后均恢复出院。1例术中吻合血管不通畅加行Warren术,术后脾肾静脉吻合口血栓形成,介入治疗效果不显著,自动出院后死亡。成功手术的15例患儿术后随访6个月至6年,平均随访31.5个月,3例术后有消化道出血复发,药物止血均较易控制,其中2例均复发1次,1例复发2次后未再出血,但出现脾大、脾功能亢进,术后5年行脾切除术。15例均生长发育良好。结论Rex分流联合断流、脾动脉结扎术治疗小儿门静脉海绵样变所致门静脉高压症效果确切。
基金Supported by Natural Science Foundation of Shandong Province(ZR2013CQ006)
文摘[Objective]The paper was to analyze the pathogenesis of Escherichia coli O123 from rex rabbit. [Method]E. coli O123 isolated from rabbit liver with diarrhea symptom in scale rex rabbit farm was intraperitoneally injected into 18- 22 g Kunming mice,and its pathogenicity was determined by clinical symptoms and pathological examination. [Result]When the inoculation concentration was about 8. 5 × 107 CFU /mL,Kunming mice appeared the clinical symptoms of drooping spirit,diarrhea and gathering,and the mortality reached 50%. Anatomical examination found that intestinal wall was thinning and intestinal mucosa was bleeding. [Conclusion]E. coli from rex rabbit has strong pathogenicity,and establishing animal model with Kunming mice to study its pathogenesis is of great reference significance for diagnosis and prevention of E. coli disease of rex rabbit.
文摘Oedipus Rex,which was created by Sophocles,is a famous tragedy.Although Oedipus in this play tries very hard to find his origin and self-identity,it is not necessarily the reason for his downfall.The real reason he was so tragic is that he had no control of himself,making things worse by his arrogance,ostentation and fierce-temptation and therefore inevitably fulfilled his fate no matter how hard he tries to escape.
文摘Loco-regional recurrence after potentially curative resection remains a problem in hilar cholangiocarcinoma. Hilar dissection risks local spillage of tumor cells leading to suboptimal disease free survival. We have developed a new technique of radical resection for hilar cholangiocarcinoma based on the distinctive anatomy of the Rex recess of the liver, which has been assessed in two patients with locally advanced hilar cholangiocarcinoma. This technique included a right hepatectomy with en-bloc resection of the hepatoduodenal ligament and portal venous reconstruction to the left portal vein at the Rex recess. Both patients had R0 resection and have been disease-free for 26 and 38 months, respectively.
文摘BACKGROUND The Rex shunt was widely used as the preferred surgical approach for cavernous transformation of the portal vein(CTPV)in children that creates a bypass between the superior mesenteric vein and the intrahepatic left portal vein(LPV).This procedure can relieve portal hypertension and restore physiological hepatopetal flow.However,the modified procedure is technically demanding because it is difficult to make an end-to-end anastomosis of a bypass to a hypoplastic LPV.Many studies reported using a recanalized umbilical vein as a conduit to resolve this problem.However,the feasibility of umbilical vein recanalization for a Rex shunt has not been fully investigated.AIM To investigate the efficacy of a recanalized umbilical vein as a conduit for a Rex shunt on CTPV in children by ultrasonography.METHODS A total of 47 children who were diagnosed with CTPV with prehepatic portal hypertension in the Second Hospital,Cheeloo College of Medicine,Shandong University,were enrolled in this study.Fifteen children received a recanalized umbilical vein as a conduit for a Rex shunt surgery and were enrolled in group I.Thirty-two children received the classic Rex shunt surgery and were enrolled in group II.The sonographic features of the two groups related to intraoperative and postoperative variation in terms of bypass vessel and the LPV were compared.RESULTS The patency rate of group I(60.0%,9/15)was significantly lower than that of group II(87.5%,28/32)7 d after(on the 8th d)operation(P<0.05).After clinical anticoagulation treatment for 3 mo,there was no significant difference in the patency rate between group I(86.7%,13/15)and group II(90.6%,29/32)(P>0.05).Moreover,3 mo after(at the beginning of the 4th mo)surgery,the inner diameter significantly widened and flow velocity notably increased for the bypass vessels and the sagittal part of the LPV compared to intraoperative values in both shunt groups(P<0.05).However,there was no significant difference between the two surgical groups 3 mo after surgery(P>0.05).CONCLUSION For children with hypoplastic LPV in the Rex recessus,using a recanalized umbilical vein as a conduit for a Rex shunt may be an effective procedure for CTPV treatment.
基金funded by National Special Research Fundfor Public Welfare ( Agriculture) of China ( 3-52,meat rabbit)
文摘[ Objective] To study the effects of diets with different com-to-soybean ratios on production performance of lactational Rex rabbits and select the best feed formula. [Method] A total of 80 lactational healthy Rex rabbits （similar age, body weight and delivery time） were randomly divided into five groups, 16 in each group. The Rex rabbits in group I were fed with corn-based meal diet, group II with soybean-based meal diet, group III with the developed corn-soybean meal diet, group IV with corn-soybean meal free diet, and group CK with conventional corn-soybean meal diet. During the lactation period, the changes in the lactation performance, growth rate of baby rabbits, weight and feed costs were observed. [ Result] The lactation performance of mother rabbits and the growth rate of baby rabbits in the experimental groups were similar to that in the control group. The weaning survival rate of the group III was the highest, but it was not significantly higher than that of the control group. The weaning survival rate of the other three groups was lower than that of the control group （P〈0.05）. The weight loss of mother rabbits in the group I, II and III was not significantly different from that of the control group, but the weight loss of the group IV was higher than that of the control group （ P 〈 0.01 ）. [ Conclusion] Diets with appropriate corn-to-soybean ratios not only reduce feed costs but also give the best feeding effects.
