Electroceuticals are medical devices that employ electric signals to alter the activity of specific nerve fibers to achieve therapeutic effects. The rapid growth of RF microelectronics has resulted in the development ...Electroceuticals are medical devices that employ electric signals to alter the activity of specific nerve fibers to achieve therapeutic effects. The rapid growth of RF microelectronics has resulted in the development of very small, portable, and inexpensive shortwave and microwave radio frequency (RF) amplifiers, raising the possibility of utilizing these new RF technologies to develop non-contact electroceutical devices. However, the bio-electromagnetics literature suggests that beyond 10 MHz, RF fields cannot influence biological tissue, beyond simple heating, because effective demodulation mechanisms at these frequencies do not exist in the body. However, RF amplifiers operating at or near saturation have non-linear interactions with complex loads, and if body tissue creates a complex loading condition, the opportunity exists for the coupled system to produce non-linear effects, that is, the equivalent of demodulation may occur. Correspondingly, exposure of tissue to pulsed RF energy could result in the creation of low frequency demodulation components capable of influencing tissue activity. Here, we develop a one-dimen- sional, numerical simulation to investigate the complex loading conditions under which such demodulation could arise. Applying these results in a physical prototype device, we show that up to7.5% demodulation can be obtained for a 40 MHz RF field pulsed at 1 KHz. Implications for this research include the possibility of developing wearable, electromagnetic electroceutical de- vices.展开更多
A large-area high-power radio-frequency（RF） driven ion source was developed for positive and negative neutral beam injectors at the Korea Atomic Energy Research Institute（KAERI）. The RF ion source consists of a dr...A large-area high-power radio-frequency（RF） driven ion source was developed for positive and negative neutral beam injectors at the Korea Atomic Energy Research Institute（KAERI）. The RF ion source consists of a driver region, including a helical antenna and a discharge chamber, and an expansion region. RF power can be transferred at up to 10 kW with a fixed frequency of 2 MHz through an optimized RF matching system. An actively water-cooled Faraday shield is located inside the driver region of the ion source for the stable and steady-state operations of high-power RF discharge. Plasma ignition of the ion source is initiated by the injection of argongas without a starter-filament heating, and the argon-gas is then slowly exchanged by the injection of hydrogen-gas to produce pure hydrogen plasmas. The uniformities of the plasma parameter,such as a plasma density and an electron temperature, are measured at the lowest area of the driver region using two RF-compensated electrostatic probes along the direction of the shortand long-dimensions of the driver region. The plasma parameters will be compared with those obtained at the lowest area of the expansion bucket to analyze the plasma expansion properties from the driver region to the expansion region.展开更多
Ring footings are suitable for the structures like tall transmission towers, chimneys, silos and oil storages.These types of structures are susceptible to horizontal loads(wind load) in addition to their dead weight.I...Ring footings are suitable for the structures like tall transmission towers, chimneys, silos and oil storages.These types of structures are susceptible to horizontal loads(wind load) in addition to their dead weight.In the literature, very little or no effort has been made to study the effect of ring footing resting on reinforced sand when subjected to eccentric, inclined and/or eccentric-inclined loadings. This paper aims to study the behavior of ring footing resting on loose sand and/or compacted randomly distributed fiberreinforced sand(RDFS) when subjected to eccentric(0 B, 0.05 B and 0.1 B, where B is the outer diameter of ring footing), inclined(0°,5°,10°, 15°,-5°,-10° and-15°)and eccentric-inclined loadings by using a finite element(FE) software PLAXIS 3 D. The behavior of ring footing is studied by using a dimensionless factor called reduction factor(RF). The numerical model used in the PLAXIS 3 D has been validated by conducting model plate load tests. Moreover, an empirical expression using regression analysis has been presented which will be helpful in plotting a load-settlement curve for the ring footing.展开更多
文摘Electroceuticals are medical devices that employ electric signals to alter the activity of specific nerve fibers to achieve therapeutic effects. The rapid growth of RF microelectronics has resulted in the development of very small, portable, and inexpensive shortwave and microwave radio frequency (RF) amplifiers, raising the possibility of utilizing these new RF technologies to develop non-contact electroceutical devices. However, the bio-electromagnetics literature suggests that beyond 10 MHz, RF fields cannot influence biological tissue, beyond simple heating, because effective demodulation mechanisms at these frequencies do not exist in the body. However, RF amplifiers operating at or near saturation have non-linear interactions with complex loads, and if body tissue creates a complex loading condition, the opportunity exists for the coupled system to produce non-linear effects, that is, the equivalent of demodulation may occur. Correspondingly, exposure of tissue to pulsed RF energy could result in the creation of low frequency demodulation components capable of influencing tissue activity. Here, we develop a one-dimen- sional, numerical simulation to investigate the complex loading conditions under which such demodulation could arise. Applying these results in a physical prototype device, we show that up to7.5% demodulation can be obtained for a 40 MHz RF field pulsed at 1 KHz. Implications for this research include the possibility of developing wearable, electromagnetic electroceutical de- vices.
基金supported by the Ministry of Science,ICT and Future Planning of the Republic of Korea under the ITER Technology R&D ProgramNational R&D Program Through the National Research Foundation of Korea(NRF)Funded by the Ministry of Science,ICT&Future Planning(NRF-2014M1A7A1A03045372)
文摘A large-area high-power radio-frequency（RF） driven ion source was developed for positive and negative neutral beam injectors at the Korea Atomic Energy Research Institute（KAERI）. The RF ion source consists of a driver region, including a helical antenna and a discharge chamber, and an expansion region. RF power can be transferred at up to 10 kW with a fixed frequency of 2 MHz through an optimized RF matching system. An actively water-cooled Faraday shield is located inside the driver region of the ion source for the stable and steady-state operations of high-power RF discharge. Plasma ignition of the ion source is initiated by the injection of argongas without a starter-filament heating, and the argon-gas is then slowly exchanged by the injection of hydrogen-gas to produce pure hydrogen plasmas. The uniformities of the plasma parameter,such as a plasma density and an electron temperature, are measured at the lowest area of the driver region using two RF-compensated electrostatic probes along the direction of the shortand long-dimensions of the driver region. The plasma parameters will be compared with those obtained at the lowest area of the expansion bucket to analyze the plasma expansion properties from the driver region to the expansion region.
文摘Ring footings are suitable for the structures like tall transmission towers, chimneys, silos and oil storages.These types of structures are susceptible to horizontal loads(wind load) in addition to their dead weight.In the literature, very little or no effort has been made to study the effect of ring footing resting on reinforced sand when subjected to eccentric, inclined and/or eccentric-inclined loadings. This paper aims to study the behavior of ring footing resting on loose sand and/or compacted randomly distributed fiberreinforced sand(RDFS) when subjected to eccentric(0 B, 0.05 B and 0.1 B, where B is the outer diameter of ring footing), inclined(0°,5°,10°, 15°,-5°,-10° and-15°)and eccentric-inclined loadings by using a finite element(FE) software PLAXIS 3 D. The behavior of ring footing is studied by using a dimensionless factor called reduction factor(RF). The numerical model used in the PLAXIS 3 D has been validated by conducting model plate load tests. Moreover, an empirical expression using regression analysis has been presented which will be helpful in plotting a load-settlement curve for the ring footing.
