Liver cancer represents a grave hepatic condition and constitutes a significant global health concern.Surgical resection remains the principal therapeutic modality for liver cancer.Nevertheless,perioperative malnutrit...Liver cancer represents a grave hepatic condition and constitutes a significant global health concern.Surgical resection remains the principal therapeutic modality for liver cancer.Nevertheless,perioperative malnutrition exerts a notable impact on patients with liver cancer,emerging as an independent risk factor for disease mortality and adverse outcomes.Hence,precise nutritional diagnosis and timely nutritional support hold the potential to enhance therapeutic efficacy and quality of life for liver cancer patients.This study represents a meticulous foray into the literature,extracting data from PubMed,Web of Science,and EMBASE databases,with a focus on the past 5 years.It scrutinizes the impact of malnutrition on patients undergoing liver cancer surgery,the etiological underpinnings of malnutrition within this patient cohort,the critical assessment of perioperative nutritional status,and the strategic approaches to nutritional support.Utilizing rigorous inclusion and exclusion criteria,the amassed scholarly works are meticulously synthesized,methodically organized,and categorically elaborated upon.Ultimately,the authors propose the incorporation of a multidisciplinary nutrition management team during the perioperative period,comprising nutritionists,pharmacists,physicians,nurses,psychologists,and rehabilitation therapists,among other specialized professionals.Together,they collaborate to devise and implement personalized nutritional support plans,monitor patients’nutritional status,and make necessary adjustments as required.Through comprehensive management and intervention,improvements in the nutritional status of liver cancer patients can be achieved,thereby enhancing surgical success rates and facilitating postoperative recovery.It is believed that this manuscript will offer valuable insights to advance the nutritional management during the perioperative phase of liver cancer,aiding in ameliorating patients'nutritional status and treatment outcomes.展开更多
目的探讨临床决策支持系统(CDSS)在原发性肝癌患者围手术期护理中的应用价值。方法回顾性分析2022年1月至2023年10月河南省人民医院收治的48例围手术期接受常规护理的原发性肝癌患者资料,纳入对照组;采集同期医院收治的48例围手术期接...目的探讨临床决策支持系统(CDSS)在原发性肝癌患者围手术期护理中的应用价值。方法回顾性分析2022年1月至2023年10月河南省人民医院收治的48例围手术期接受常规护理的原发性肝癌患者资料,纳入对照组;采集同期医院收治的48例围手术期接受基于CDSS的护理管理的原发性肝癌患者资料,纳入观察组。查阅并比较两组护理质量(护理级别符合率、护理诊断正确率、护理处理及时率)、术后1、3、72 d时疼痛程度[采用疼痛数字评分法(NRS)评估]、护理期间并发症发生情况。结果观察组护理级别符合率、护理诊断正确率、护理处理及时率均高于对照组(P<0.05)。两组术后1、3、5 d NRS评分组间、时间、交互效应有统计学意义(P<0.05)。两组术后3、5 d NRS评分均较术后1 d高,术后5 d较术后3 d高(P<0.05)。两组术后1 d NRS评分差异无统计学意义(P>0.05),观察组术后3、5 d时NRS评分均低于对照组(P<0.05)。观察组护理期间并发症总发生率低于对照组(P<0.05)。结论基于CDSS的护理管理可提高原发性肝癌患者围手术期护理质量,减轻患者术后疼痛,降低术后并发症发生风险。展开更多
目的检索、评价和整合肝癌患者围术期运动干预的最佳证据,为临床医护人员提供循证依据。方法按照“6S”证据资源金字塔模型,自上而下进行证据检索。数据库包括:BMJ Best Practice,UpToDate,国际指南协作网,美国国立指南网,英国国家卫生...目的检索、评价和整合肝癌患者围术期运动干预的最佳证据,为临床医护人员提供循证依据。方法按照“6S”证据资源金字塔模型,自上而下进行证据检索。数据库包括:BMJ Best Practice,UpToDate,国际指南协作网,美国国立指南网,英国国家卫生与临床优化研究所,苏格兰院际指南网,医脉通,Cochrane library,JBI循证卫生保健数据库,Web of Science,PubMed,Embase,CINAHL,SinoMed,中国知网,万方数据库,美国癌症协会,美国运动医学会,国际肝癌协会。时间为2010年1月至2022年6月。由2名研究者对纳入文献质量进行评价,并提取符合标准的文献证据。结果共纳入22篇文献,从运动的重要性、运动前评估、术前运动方案、术后运动方案、运动监测、健康教育、效果评价7个方面共总结出26条证据。结论本研究总结了肝癌患者围术期运动干预的最佳证据,可为临床医护人员循证护理实践提供证据。展开更多
Objective： To observe the clinical effect of radiofrequency ablation （RFA） combined with transcatheter arterial chemoembolization （TACE） for advanced hepatocellnlar carcinoma （HCC）. Methods： A total of 92 ease...Objective： To observe the clinical effect of radiofrequency ablation （RFA） combined with transcatheter arterial chemoembolization （TACE） for advanced hepatocellnlar carcinoma （HCC）. Methods： A total of 92 eases of advanced primary liver cancer underwent TACE and RFA treatment from June 2005 to 2011 at the Department of Hepatobiliary Surgery, the First Affiliated Hospital of Bengbu Medical College. A total of 88 cases with complete clinical treatment and follow-up data were divided into two groups： 43 patients treated with TACE （TACE group） and 45 patients that received TACE combined with RFA treatment （TACE ＋ RFA group）. After clinical data assessment, tumor size and survival status were not significantly different between the groups as determined by stratified analysis. Results： Before and after surgery, spiral CT radiography and color comparison observed ablation conditions. The tumor necrosis rates after treatment （CR ＋ PR） were 67.4% （29/43） and 91.1% （41/45） for the TACE and combined treatment groups, respectively, and the difference was statistically significant （P〈0.05）. The quality of life was significantly improved for patients undergoing TACE ~ RFA compared with the control group. Survival duration was not significantly different in patients undergoing TACE ~ RFA compared with the control group. Conclusions： In this study, the effect of RFA combined with TACE treatment was better than TACE alone in treating advanced HCC.展开更多
基金National Natural Science Foundation of China,No 81701888Science and Technology Program of Sichuan Province,No.2023YFS0206Scientific Research Project of Sichuan Cadre Health Committee,No.2022-211.
文摘Liver cancer represents a grave hepatic condition and constitutes a significant global health concern.Surgical resection remains the principal therapeutic modality for liver cancer.Nevertheless,perioperative malnutrition exerts a notable impact on patients with liver cancer,emerging as an independent risk factor for disease mortality and adverse outcomes.Hence,precise nutritional diagnosis and timely nutritional support hold the potential to enhance therapeutic efficacy and quality of life for liver cancer patients.This study represents a meticulous foray into the literature,extracting data from PubMed,Web of Science,and EMBASE databases,with a focus on the past 5 years.It scrutinizes the impact of malnutrition on patients undergoing liver cancer surgery,the etiological underpinnings of malnutrition within this patient cohort,the critical assessment of perioperative nutritional status,and the strategic approaches to nutritional support.Utilizing rigorous inclusion and exclusion criteria,the amassed scholarly works are meticulously synthesized,methodically organized,and categorically elaborated upon.Ultimately,the authors propose the incorporation of a multidisciplinary nutrition management team during the perioperative period,comprising nutritionists,pharmacists,physicians,nurses,psychologists,and rehabilitation therapists,among other specialized professionals.Together,they collaborate to devise and implement personalized nutritional support plans,monitor patients’nutritional status,and make necessary adjustments as required.Through comprehensive management and intervention,improvements in the nutritional status of liver cancer patients can be achieved,thereby enhancing surgical success rates and facilitating postoperative recovery.It is believed that this manuscript will offer valuable insights to advance the nutritional management during the perioperative phase of liver cancer,aiding in ameliorating patients'nutritional status and treatment outcomes.
文摘目的探讨临床决策支持系统(CDSS)在原发性肝癌患者围手术期护理中的应用价值。方法回顾性分析2022年1月至2023年10月河南省人民医院收治的48例围手术期接受常规护理的原发性肝癌患者资料,纳入对照组;采集同期医院收治的48例围手术期接受基于CDSS的护理管理的原发性肝癌患者资料,纳入观察组。查阅并比较两组护理质量(护理级别符合率、护理诊断正确率、护理处理及时率)、术后1、3、72 d时疼痛程度[采用疼痛数字评分法(NRS)评估]、护理期间并发症发生情况。结果观察组护理级别符合率、护理诊断正确率、护理处理及时率均高于对照组(P<0.05)。两组术后1、3、5 d NRS评分组间、时间、交互效应有统计学意义(P<0.05)。两组术后3、5 d NRS评分均较术后1 d高,术后5 d较术后3 d高(P<0.05)。两组术后1 d NRS评分差异无统计学意义(P>0.05),观察组术后3、5 d时NRS评分均低于对照组(P<0.05)。观察组护理期间并发症总发生率低于对照组(P<0.05)。结论基于CDSS的护理管理可提高原发性肝癌患者围手术期护理质量,减轻患者术后疼痛,降低术后并发症发生风险。
文摘目的检索、评价和整合肝癌患者围术期运动干预的最佳证据,为临床医护人员提供循证依据。方法按照“6S”证据资源金字塔模型,自上而下进行证据检索。数据库包括:BMJ Best Practice,UpToDate,国际指南协作网,美国国立指南网,英国国家卫生与临床优化研究所,苏格兰院际指南网,医脉通,Cochrane library,JBI循证卫生保健数据库,Web of Science,PubMed,Embase,CINAHL,SinoMed,中国知网,万方数据库,美国癌症协会,美国运动医学会,国际肝癌协会。时间为2010年1月至2022年6月。由2名研究者对纳入文献质量进行评价,并提取符合标准的文献证据。结果共纳入22篇文献,从运动的重要性、运动前评估、术前运动方案、术后运动方案、运动监测、健康教育、效果评价7个方面共总结出26条证据。结论本研究总结了肝癌患者围术期运动干预的最佳证据,可为临床医护人员循证护理实践提供证据。
基金Natural Science Research Program of Education Bureau of Anhui Province (No. J2009A163)
文摘Objective： To observe the clinical effect of radiofrequency ablation （RFA） combined with transcatheter arterial chemoembolization （TACE） for advanced hepatocellnlar carcinoma （HCC）. Methods： A total of 92 eases of advanced primary liver cancer underwent TACE and RFA treatment from June 2005 to 2011 at the Department of Hepatobiliary Surgery, the First Affiliated Hospital of Bengbu Medical College. A total of 88 cases with complete clinical treatment and follow-up data were divided into two groups： 43 patients treated with TACE （TACE group） and 45 patients that received TACE combined with RFA treatment （TACE ＋ RFA group）. After clinical data assessment, tumor size and survival status were not significantly different between the groups as determined by stratified analysis. Results： Before and after surgery, spiral CT radiography and color comparison observed ablation conditions. The tumor necrosis rates after treatment （CR ＋ PR） were 67.4% （29/43） and 91.1% （41/45） for the TACE and combined treatment groups, respectively, and the difference was statistically significant （P〈0.05）. The quality of life was significantly improved for patients undergoing TACE ~ RFA compared with the control group. Survival duration was not significantly different in patients undergoing TACE ~ RFA compared with the control group. Conclusions： In this study, the effect of RFA combined with TACE treatment was better than TACE alone in treating advanced HCC.
文摘目的 探讨加速康复外科(ERAS)在原发性肝癌(PLC)肝切除围手术期应用中的安全性及有效性。方法 回顾性分析2014年1月至2018年9月在南华大学附属第一医院肝胆胰外科因PLC行肝切除手术的109例患者临床资料。根据围术期管理方法不同分为ERAS组(n=56)和传统组(n=53),然后基于倾向性评分匹配(PSM)法比较两组患者术中情况及术后恢复情况。结果 两组患者的基线资料经PSM后平衡良好,每组患者均为40例。两组在基线一般资料、手术时间、术中出血量及输血率方面比较,均无统计学差异(P>0.05)。与传统组相比,ERAS组术后第1、4、7天WBC更低,但ALB水平更高(P<0.05)。ERAS组患者术后进食更早[(2.03±0.36)d vs (4.33±2.12)d,P<0.05],下床活动时间更早[(50.38±24.76)h vs(79.05±40.73)h,P<0.05],肛门首次排气时间更早[(2.63±1.12)d vs (3.28±0.88)d,P<0.05],腹腔引流管拔除时间更早[(5.03±0.36)d vs (9.05±3.69)d,P<0.05],且术后住院时间缩短[(13.48±4.95)d vs(16.00±5.52)d,P<0.05],住院总费用降低[(4.15±0.49)万元vs (5.39±1.74)万元,P<0.05],术后中重度疼痛发生率更低(30.0%vs 60.0%,P<0.05)。结论 ERAS应用于PLC肝切除围手术期是安全有效的。
