目的探究达标理论结合协同干预对老年高血压患者血压控制情况及症状自评量表(symptom checklist-90,SCL-90)、健康调查简表(medical outcomes study short form-36,SF-36)评分的影响。方法选择2017-08至2019-08于空军杭州特勤疗养中心...目的探究达标理论结合协同干预对老年高血压患者血压控制情况及症状自评量表(symptom checklist-90,SCL-90)、健康调查简表(medical outcomes study short form-36,SF-36)评分的影响。方法选择2017-08至2019-08于空军杭州特勤疗养中心接受治疗的老年高血压患者120例作为研究对象,随机分为研究组(n=60)和对照组(n=60)。研究组给予达标理论结合协同干预进行护理,对照组患者给予达标理论进行护理。观察两组患者的服药依从性、血压状况、家庭功能及SCL-90、SF-36评分。结果干预后,两组患者的服药依从性得分均显著增高(P=0.003、0.001),且研究组显著高于对照组(P=0.025);干预后,两组患者的家庭功能评分均显著增高(P=0.001、0.001),且研究组显著高于对照组(P=0.001);干预后,两组患者的舒张压和收缩压均得到下降,且研究组舒张压和收缩压低于对照组(P<0.05);干预后,两组患者的SCL-90降低,SF-36升高,且研究组更加显著(P<0.05)。结论达标理论结合协同干预能够显著增加老年高血压患者的服药依从性,控制患者血压和改善患者的家庭功能,降低SCL-90和升高SF-36评分。展开更多
Background:The upper limit for liver resections in rats is approximately 90%.In the early postoperative phase,mortality increases.The aim of the present study was to validate the rat model of 90%partial hepatectomy(PH...Background:The upper limit for liver resections in rats is approximately 90%.In the early postoperative phase,mortality increases.The aim of the present study was to validate the rat model of 90%partial hepatectomy(PH)as a model of post-hepatectomy liver failure(PHLF).Further,we wanted to test a quantitative scoring system as a detector of lethal outcomes caused by PHLF in rats.Methods:Sixty-eight rats were randomized to 90%PH,sham operation,or no sur-gery.Further,block randomization was performed based on time of euthanization:12,24,or 48 h after surgery.A general distress score(GDS)≥10 during the day or≥6 at midnight prompted early euthanization and classification as nonsurvivor.Animals euthanized as planned were classified as survivors.During euthanization,blood and liver tissue were collected,and liver-specific biochemistry was evaluated.Results:Based on the biochemical results,all animals subjected to 90%PH expe-rienced PHLF.Seventeen rats were euthanized due to irreversible PHLF.The GDS increased for nonsurvivors within 12–18 h after surgery.The mean time for euthaniza-tion was 27 h after surgery.Conclusion:Based on the GDS and liver-specific biochemistry,we concluded that the model of 90%PH seems to be a proper model for investigating PHLF in rats.As a high GDS is associated with increased mortality,the GDS appears to be valuable in detect-ing lethal outcomes caused by PHLF in rats.展开更多
文摘目的探究达标理论结合协同干预对老年高血压患者血压控制情况及症状自评量表(symptom checklist-90,SCL-90)、健康调查简表(medical outcomes study short form-36,SF-36)评分的影响。方法选择2017-08至2019-08于空军杭州特勤疗养中心接受治疗的老年高血压患者120例作为研究对象,随机分为研究组(n=60)和对照组(n=60)。研究组给予达标理论结合协同干预进行护理,对照组患者给予达标理论进行护理。观察两组患者的服药依从性、血压状况、家庭功能及SCL-90、SF-36评分。结果干预后,两组患者的服药依从性得分均显著增高(P=0.003、0.001),且研究组显著高于对照组(P=0.025);干预后,两组患者的家庭功能评分均显著增高(P=0.001、0.001),且研究组显著高于对照组(P=0.001);干预后,两组患者的舒张压和收缩压均得到下降,且研究组舒张压和收缩压低于对照组(P<0.05);干预后,两组患者的SCL-90降低,SF-36升高,且研究组更加显著(P<0.05)。结论达标理论结合协同干预能够显著增加老年高血压患者的服药依从性,控制患者血压和改善患者的家庭功能,降低SCL-90和升高SF-36评分。
基金Arvid Nilssons FoundationFabrikant Einar Willumsen Foundation+1 种基金Familien Hede Nielsen FoundationKobmand Sven Hansen og Hustru Ina Hansen Foundation
文摘Background:The upper limit for liver resections in rats is approximately 90%.In the early postoperative phase,mortality increases.The aim of the present study was to validate the rat model of 90%partial hepatectomy(PH)as a model of post-hepatectomy liver failure(PHLF).Further,we wanted to test a quantitative scoring system as a detector of lethal outcomes caused by PHLF in rats.Methods:Sixty-eight rats were randomized to 90%PH,sham operation,or no sur-gery.Further,block randomization was performed based on time of euthanization:12,24,or 48 h after surgery.A general distress score(GDS)≥10 during the day or≥6 at midnight prompted early euthanization and classification as nonsurvivor.Animals euthanized as planned were classified as survivors.During euthanization,blood and liver tissue were collected,and liver-specific biochemistry was evaluated.Results:Based on the biochemical results,all animals subjected to 90%PH expe-rienced PHLF.Seventeen rats were euthanized due to irreversible PHLF.The GDS increased for nonsurvivors within 12–18 h after surgery.The mean time for euthaniza-tion was 27 h after surgery.Conclusion:Based on the GDS and liver-specific biochemistry,we concluded that the model of 90%PH seems to be a proper model for investigating PHLF in rats.As a high GDS is associated with increased mortality,the GDS appears to be valuable in detect-ing lethal outcomes caused by PHLF in rats.
