In order to reveal the immune antibody levels and immune effect of livestock and poultry in the locality,we performed antibody surveillance on severe animal diseases in 17 livestock and poultry fields in six administr...In order to reveal the immune antibody levels and immune effect of livestock and poultry in the locality,we performed antibody surveillance on severe animal diseases in 17 livestock and poultry fields in six administrative districts of Wuhan City. The results showed that the vaccines had a good protective efficacy on highly pathogenic avian influenza( HPAI) and Newcastle disease( ND) in Wuhan City. The whole antibody levels kept above the ministerial standard( 】 70%).However,the vaccine immunity of porcine reproductive and respiratory syndrome( PRRS),swine fever( SF) and foot and mouth disease( FMD) was still poorly protective. The data indicated that the vaccines are protecting the severe animal diseases well,but there are still some potential security holes in some administrative districts.展开更多
目的分析2019—2022年湖北省狂犬病疫苗疑似预防接种异常反应(Adverse events following immunization,AEFI)监测情况,评价相关疫苗安全性。方法通过“中国疾病预防控制信息系统”和“湖北省免疫规划信息系统”收集2019—2022年湖北省...目的分析2019—2022年湖北省狂犬病疫苗疑似预防接种异常反应(Adverse events following immunization,AEFI)监测情况,评价相关疫苗安全性。方法通过“中国疾病预防控制信息系统”和“湖北省免疫规划信息系统”收集2019—2022年湖北省狂犬病疫苗接种后AEFI个案信息以及狂犬病疫苗接种情况,描述性分析AEFI发生特征和报告发生率。结果2019—2022年湖北省共报告狂犬病疫苗AEFI个案2308例,年均报告发生率为22.00/10万剂;不同年份报告发生率差异有统计学意义(χ^(2)=452.92,P<0.01)。所有AEFI个案中,一般反应、异常反应分别占96.23%、3.16%;严重AEFI、非严重AEFI报告发生率分别为0.14/10万剂、21.86/10万剂。各市(州)均有AEFI报告(仅2021年鄂州市为零报告),报告总例数居前3位的分别是荆州市、宜昌市和襄阳市。报告的AEFI中,男、女性别比为1.02∶1;2~6岁儿童占47.44%;第2、3季度报告例数较多,占比分别为35.79%、32.63%。96.92%的AEFI个案接种后至发生AEFI时间间隔≤1 d。不同制作工艺类型狂犬病疫苗AEFI报告发生率差异有统计学意义(χ^(2)=238.92,P<0.01)。冻干狂犬病疫苗(Vero细胞)的AEFI报告发生率高于其他3种狂犬病疫苗。结论2019—2022年湖北省狂犬病疫苗AEFI报告发生率呈波动下降,报告的AEFI以一般反应为主,非严重AEFI为罕见,严重AEFI为十分罕见,安全性良好。展开更多
基金Supported by High Tech Industry Development Plan of Wuhan City(201220812240-6)
文摘In order to reveal the immune antibody levels and immune effect of livestock and poultry in the locality,we performed antibody surveillance on severe animal diseases in 17 livestock and poultry fields in six administrative districts of Wuhan City. The results showed that the vaccines had a good protective efficacy on highly pathogenic avian influenza( HPAI) and Newcastle disease( ND) in Wuhan City. The whole antibody levels kept above the ministerial standard( 】 70%).However,the vaccine immunity of porcine reproductive and respiratory syndrome( PRRS),swine fever( SF) and foot and mouth disease( FMD) was still poorly protective. The data indicated that the vaccines are protecting the severe animal diseases well,but there are still some potential security holes in some administrative districts.
文摘目的分析2019—2022年湖北省狂犬病疫苗疑似预防接种异常反应(Adverse events following immunization,AEFI)监测情况,评价相关疫苗安全性。方法通过“中国疾病预防控制信息系统”和“湖北省免疫规划信息系统”收集2019—2022年湖北省狂犬病疫苗接种后AEFI个案信息以及狂犬病疫苗接种情况,描述性分析AEFI发生特征和报告发生率。结果2019—2022年湖北省共报告狂犬病疫苗AEFI个案2308例,年均报告发生率为22.00/10万剂;不同年份报告发生率差异有统计学意义(χ^(2)=452.92,P<0.01)。所有AEFI个案中,一般反应、异常反应分别占96.23%、3.16%;严重AEFI、非严重AEFI报告发生率分别为0.14/10万剂、21.86/10万剂。各市(州)均有AEFI报告(仅2021年鄂州市为零报告),报告总例数居前3位的分别是荆州市、宜昌市和襄阳市。报告的AEFI中,男、女性别比为1.02∶1;2~6岁儿童占47.44%;第2、3季度报告例数较多,占比分别为35.79%、32.63%。96.92%的AEFI个案接种后至发生AEFI时间间隔≤1 d。不同制作工艺类型狂犬病疫苗AEFI报告发生率差异有统计学意义(χ^(2)=238.92,P<0.01)。冻干狂犬病疫苗(Vero细胞)的AEFI报告发生率高于其他3种狂犬病疫苗。结论2019—2022年湖北省狂犬病疫苗AEFI报告发生率呈波动下降,报告的AEFI以一般反应为主,非严重AEFI为罕见,严重AEFI为十分罕见,安全性良好。
