Objective To analyse comparatively the relevant data from bone tumor registries in China, Japan, and the United States Methods The data of 38?959 histologically confirmed primary bone tumors collected by the Chines...Objective To analyse comparatively the relevant data from bone tumor registries in China, Japan, and the United States Methods The data of 38?959 histologically confirmed primary bone tumors collected by the Chinese Bone Tumor Registry 1957 1988, 20?272 collected by the Japanese Bone Tumor Registry 1972 1990, and 11087 diagnosed and treated at Mayo Clinic, USA were used for comparative analysis by race, age, sex and skeletal distribution For reliability, we used ratios of different tumors to osteosarcoma for frequency analysis We also included some data from the SEER 1973 1987 as well as from Memorial Sloan Kettering Cancer Center, USA Results The relative frequency of osteosarcoma (OS) is higher in China and Japan than in the United States There were only limited number of OS patients aged over 50 years in Chinese and Japanese groups, which might be due to the lower incidence of OS subsequent to Paget's disease in Asians More osteosarcoma occurred in the flat bones in the Americans than in the Chinese and Japanese The relative frequency of chondrosarcoma (CS) was higher in the American group than in the Asian groups The average age of CS patient was younger in the Chinese than in the Japanese and the Americans The data confirmed the previous report that the incidence of Ewing sarcoma was higher in western people than in Asians The data showed that the comparative frequency of chordoma is higher in the Americans than in the Asians and that the incidence of giant cell tumor of bone is higher in the Chinese and Japanese than in the Americans Conclusion The findings from this analysis provide useful information for the epidemiologic study and the clinical diagnosis of bone tumors展开更多
Correlations among free radicals, apparent activation energy, and functional groups during lowtemperature oxidation of Jurassic coal in Northern Shaanxi were investigated by examining three coal samples collected from...Correlations among free radicals, apparent activation energy, and functional groups during lowtemperature oxidation of Jurassic coal in Northern Shaanxi were investigated by examining three coal samples collected from the Ningtiaota, Jianxin, and Shigetai coal mines. Free radical concentrations at less than 120 °C were investigated by electron spin resonance experiments while the thermogravimetric experiments were conducted to analyze apparent activation energies. In addition, Fourier transform infrared spectroscopy was employed to study the spectrum of functional groups generated in coal. The results indicated that, in decreasing order, the apparent activation energies were Shigetai > Jianxin >Ningtiaota, indicating that, from 50 to 120 °C, the Ningtiaota coal sample most easily absorbed and reacted with oxygen while the most resistant was the Shigetai coal sample. Free radical concentrations and line heights increased with increased temperature, and the line width and Lande factor showed irregular fluctuations. Functional group variations were different among these coals, and the phenol and alcohol-associated OHs, carboxyls, and aromatic ring double bonds might have had a major impact on free radical concentrations. These results were meaningful for better consideration and management of coal oxidation at low temperatures.展开更多
AIM: To evaluate the classification and severity of Crohn's disease in different racial groups.METHODS: Patients with Crohn's disease from the outpatient clinic of the University Hospital Prof. Edgard Santos w...AIM: To evaluate the classification and severity of Crohn's disease in different racial groups.METHODS: Patients with Crohn's disease from the outpatient clinic of the University Hospital Prof. Edgard Santos were enrolled in the study. This hospital is a reference centre for inflammatory bowel disease. Race was determined using self-identification. The Vienna's classification was applied for all subjects. The severity of Crohn's disease was determined according to the number of surgical procedures, hospital admissions in the last year and treatment with steroids and immunosuppressors. Statistical analysis was calculated using t test for means, χ2 or F for proportions. A P value < 0.05 was considered to be significant.RESULTS: Sixty-five patients were enrolled. Non-white patients were more frequently diagnosed with Crohn's disease in the age less than 40 years than white patients. The behaviour of disease was similar in both groups with a high frequency of the penetrating form. There was a tendency for non-white patients to have a greater frequency of hospital admissions in the last year compared to white subjects. Non-whites also had a higher rate of colonic and upper gastrointestinal involvement, and were also more frequently on treatment with immunossupressors than white patients although this difference was not statistically significant.CONCLUSION: Non-white patients with Crohn's diseasehad an earlier diagnosis and appeared to have had a more severe disease presentation than white patients.展开更多
文摘Objective To analyse comparatively the relevant data from bone tumor registries in China, Japan, and the United States Methods The data of 38?959 histologically confirmed primary bone tumors collected by the Chinese Bone Tumor Registry 1957 1988, 20?272 collected by the Japanese Bone Tumor Registry 1972 1990, and 11087 diagnosed and treated at Mayo Clinic, USA were used for comparative analysis by race, age, sex and skeletal distribution For reliability, we used ratios of different tumors to osteosarcoma for frequency analysis We also included some data from the SEER 1973 1987 as well as from Memorial Sloan Kettering Cancer Center, USA Results The relative frequency of osteosarcoma (OS) is higher in China and Japan than in the United States There were only limited number of OS patients aged over 50 years in Chinese and Japanese groups, which might be due to the lower incidence of OS subsequent to Paget's disease in Asians More osteosarcoma occurred in the flat bones in the Americans than in the Chinese and Japanese The relative frequency of chondrosarcoma (CS) was higher in the American group than in the Asian groups The average age of CS patient was younger in the Chinese than in the Japanese and the Americans The data confirmed the previous report that the incidence of Ewing sarcoma was higher in western people than in Asians The data showed that the comparative frequency of chordoma is higher in the Americans than in the Asians and that the incidence of giant cell tumor of bone is higher in the Chinese and Japanese than in the Americans Conclusion The findings from this analysis provide useful information for the epidemiologic study and the clinical diagnosis of bone tumors
基金supported by the Key Projects of the National Natural Science Foundation of China (Nos. 51504187, 51774233, and 51704226)Shaanxi Province Industrial Science and Technology Research Project (No. 2016GY-192)the China Postdoctoral Science Foundation (No. 2016-M-590963)
文摘Correlations among free radicals, apparent activation energy, and functional groups during lowtemperature oxidation of Jurassic coal in Northern Shaanxi were investigated by examining three coal samples collected from the Ningtiaota, Jianxin, and Shigetai coal mines. Free radical concentrations at less than 120 °C were investigated by electron spin resonance experiments while the thermogravimetric experiments were conducted to analyze apparent activation energies. In addition, Fourier transform infrared spectroscopy was employed to study the spectrum of functional groups generated in coal. The results indicated that, in decreasing order, the apparent activation energies were Shigetai > Jianxin >Ningtiaota, indicating that, from 50 to 120 °C, the Ningtiaota coal sample most easily absorbed and reacted with oxygen while the most resistant was the Shigetai coal sample. Free radical concentrations and line heights increased with increased temperature, and the line width and Lande factor showed irregular fluctuations. Functional group variations were different among these coals, and the phenol and alcohol-associated OHs, carboxyls, and aromatic ring double bonds might have had a major impact on free radical concentrations. These results were meaningful for better consideration and management of coal oxidation at low temperatures.
文摘AIM: To evaluate the classification and severity of Crohn's disease in different racial groups.METHODS: Patients with Crohn's disease from the outpatient clinic of the University Hospital Prof. Edgard Santos were enrolled in the study. This hospital is a reference centre for inflammatory bowel disease. Race was determined using self-identification. The Vienna's classification was applied for all subjects. The severity of Crohn's disease was determined according to the number of surgical procedures, hospital admissions in the last year and treatment with steroids and immunosuppressors. Statistical analysis was calculated using t test for means, χ2 or F for proportions. A P value < 0.05 was considered to be significant.RESULTS: Sixty-five patients were enrolled. Non-white patients were more frequently diagnosed with Crohn's disease in the age less than 40 years than white patients. The behaviour of disease was similar in both groups with a high frequency of the penetrating form. There was a tendency for non-white patients to have a greater frequency of hospital admissions in the last year compared to white subjects. Non-whites also had a higher rate of colonic and upper gastrointestinal involvement, and were also more frequently on treatment with immunossupressors than white patients although this difference was not statistically significant.CONCLUSION: Non-white patients with Crohn's diseasehad an earlier diagnosis and appeared to have had a more severe disease presentation than white patients.
