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Efficacy and safety of percutaneous transhepatic biliary radiofrequency ablation in patients with malignant obstructive jaundice 被引量:1
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作者 Ying Xing Zheng-Rong Liu +1 位作者 You-Guo Li Hong-Yi Zhang 《World Journal of Clinical Cases》 SCIE 2024年第17期2983-2988,共6页
BACKGROUND Percutaneous transhepatic cholangiodrainage(PTCD)and endoscopic retrograde cholangiopancreatography/endoscopic nasobiliary drainage are the most common clinical procedures for jaundice control in patients w... BACKGROUND Percutaneous transhepatic cholangiodrainage(PTCD)and endoscopic retrograde cholangiopancreatography/endoscopic nasobiliary drainage are the most common clinical procedures for jaundice control in patients with unresectable malignant obstructive jaundice,yet the safety and effect of endobiliary radiofrequency ablation(EB-RFA)combined PTCD is rarely reported,in this article,we report our experience of EB-RFA combined PTCD in such patients.AIM To retrospectively study the efficacy and safety of EB-RFA combined PTCD in patients with unresectable malignant obstructive jaundice.METHODS Patients with unresectable malignant obstructive jaundice treated with EB-RFA under PTCD were selected,the bile ducts of the right posterior lobe was selected as the target bile ducts in all cases.The general conditions of all patients,preoperative tumour markers,total bilirubin(TBIL),direct bilirubin(DBIL),albumin(ALB),alkaline phosphatase(ALP),and glutamyl transferase(GGT)before and on the 7th day after the procedure,as well as perioperative complications,stent patency time and patient survival were recorded.RESULTS All patients successfully completed the operation,TBIL and DBIL decreased significantly in all patients at the 7th postoperative day(P=0.009 and 0.006,respectively);the values of ALB,ALP and GGT also decreased compared with the preoperative period,but the difference was not statistically significant.Perioperative biliary bleeding occurred in 2 patients,which was improved after transfusion of blood and other conservative treatments,pancreatitis appeared in 1 patient after the operation,no serious complication and death happened after operation.Except for 3 patients with loss of visits,the stent patency rate of the remaining 14 patients was 100%71%and 29%at the 1^(st),3^(rd),and 6^(th)postoperative months respectively,with a median survival of 4 months.CONCLUSION EB-RFA under PTCD in patients with unresectable malignant obstructive jaundice has a satisfactory therapeutic effect and high safety,which is worthy of further clinical practice. 展开更多
关键词 Biliary tract tumour Malignant obstructive jaundice Percutaneous transhepatic cholangiodrainage Endoluminal radiofrequency ablation Biliary radiofrequency ablation
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Nomogram predicting the prognosis of primary liver cancer after radiofrequency ablation combined with transcatheter arterial chemoembolization 被引量:1
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作者 Hai-Hua Shen Yu-Rong Hong +4 位作者 Wen Xu Lei Chen Jun-Min Chen Zhi-Gen Yang Cai-Hong Chen 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第8期2630-2639,共10页
BACKGROUND The incidence and mortality rates of primary hepatocellular carcinoma(HCC)are high,and the conventional treatment is radiofrequency ablation(RFA)with transcatheter arterial chemoembolization(TACE);however,t... BACKGROUND The incidence and mortality rates of primary hepatocellular carcinoma(HCC)are high,and the conventional treatment is radiofrequency ablation(RFA)with transcatheter arterial chemoembolization(TACE);however,the 3-year survival rate is still low.Further,there are no visual methods to effectively predict their prognosis.AIM To explore the factors influencing the prognosis of HCC after RFA and TACE and develop a nomogram prediction model.METHODS Clinical and follow-up information of 150 patients with HCC treated using RFA and TACE in the Hangzhou Linping Hospital of Traditional Chinese Medicine from May 2020 to December 2022 was retrospectively collected and recorded.We examined their prognostic factors using multivariate logistic regression and created a nomogram prognosis prediction model using the R software(version 4.1.2).Internal verification was performed using the bootstrapping technique.The prognostic efficacy of the nomogram prediction model was evaluated using the concordance index(CI),calibration curve,and receiver operating characteristic RESULTS Of the 150 patients treated with RFA and TACE,92(61.33%)developed recurrence and metastasis.Logistic regression analysis identified six variables,and a predictive model was created.The internal validation results of the model showed a CI of 0.882.The correction curve trend of the prognosis prediction model was always near the diagonal,and the mean absolute error before and after internal validation was 0.021.The area under the curve of the prediction model after internal verification was 0.882[95%confidence interval(95%CI):0.820-0.945],with a specificity of 0.828 and sensitivity of 0.656.According to the Hosmer-Lemeshow test,χ^(2)=3.552 and P=0.895.The predictive model demonstrated a satisfactory calibration,and the decision curve analysis demonstrated its clinical applicability.CONCLUSION The prognosis of patients with HCC after RFA and TACE is affected by several factors.The developed prediction model based on the influencing parameters shows a good prognosis predictive efficacy. 展开更多
关键词 NOMOGRAM Primary liver cancer radiofrequency ablation Transcatheter arterial chemoembolization PROGNOSIS Influencing factors Decision curve analysis
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Effect of a negative DC bias on a capacitively coupled Ar plasma operated at different radiofrequency voltages and gas pressures
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作者 相垚君 王晓坤 +1 位作者 刘永新 王友年 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第5期62-71,共10页
The effect of a negative DC bias,|V_(dc)|,on the electrical parameters and discharge mode is investigated experimentally in a radiofrequency(RF)capacitively coupled Ar plasma operated at different RF voltage amplitude... The effect of a negative DC bias,|V_(dc)|,on the electrical parameters and discharge mode is investigated experimentally in a radiofrequency(RF)capacitively coupled Ar plasma operated at different RF voltage amplitudes and gas pressures.The electron density is measured using a hairpin probe and the spatio-temporal distribution of the electron-impact excitation rate is determined by phase-resolved optical emission spectroscopy.The electrical parameters are obtained based on the waveforms of the electrode voltage and plasma current measured by a voltage probe and a current probe.It was found that at a low|V_(dc)|,i.e.inα-mode,the electron density and RF current decline with increasing|V_(dc)|;meanwhile,the plasma impedance becomes more capacitive due to a widened sheath.Therefore,RF power deposition is suppressed.When|V_(dc)|exceeds a certain value,the plasma changes toα–γhybrid mode(or the discharge becomes dominated by theγ-mode),manifesting a drastically growing electron density and a moderately increasing RF current.Meanwhile,the plasma impedance becomes more resistive,so RF power deposition is enhanced with|V_(dc)|.We also found that the electrical parameters show similar dependence on|V_(dc)|at different RF voltages,andα–γmode transition occurs at a lower|V_(dc)|at a higher RF voltage.By increasing the pressure,plasma impedance becomes more resistive,so RF power deposition and electron density are enhanced.In particular,theα–γmode transition tends to occur at a lower|V_(dc)|with increase in pressure. 展开更多
关键词 rf capacitively coupled plasma DC-overlapped rf discharge power deposition discharge mode transition
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Efficacy of radiofrequency ablation combined with sorafenib for treating liver cancer complicated with portal hypertension and prognostic factors
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作者 Li-Min Yang Hong-Juan Wang +4 位作者 Shan-Lin Li Guan-Hua Gan Wen-Wen Deng Yong-Sheng Chang Lian-Feng Zhang 《World Journal of Gastroenterology》 SCIE CAS 2024年第11期1533-1544,共12页
BACKGROUND Patients with liver cancer complicated by portal hypertension present complex challenges in treatment.AIM To evaluate the efficacy of radiofrequency ablation in combination with sorafenib for improving live... BACKGROUND Patients with liver cancer complicated by portal hypertension present complex challenges in treatment.AIM To evaluate the efficacy of radiofrequency ablation in combination with sorafenib for improving liver function and its impact on the prognosis of patients with this condition.METHODS Data from 100 patients with liver cancer complicated with portal hypertension from May 2014 to March 2019 were analyzed and divided into a study group(n=50)and a control group(n=50)according to the treatment regimen.The research group received radiofrequency ablation(RFA)in combination with sorafenib,and the control group only received RFA.The short-term efficacy of both the research and control groups was observed.Liver function and portal hypertension were compared before and after treatment.Alpha-fetoprotein(AFP),glypican-3(GPC-3),and AFP-L3 levels were compared between the two groups prior to and after treatment.The occurrence of adverse reactions in both groups was observed.The 3-year survival rate was compared between the two groups.Basic data were compared between the survival and non-surviving groups.To identify the independent risk factors for poor prognosis in patients with liver cancer complicated by portal hypertension,multivariate logistic regression analysis was employed.RESULTS When comparing the two groups,the research group's total effective rate(82.00%)was significantly greater than that of the control group(56.00%;P<0.05).Following treatment,alanine aminotransferase and aspartate aminotransferase levels increased,and portal vein pressure decreased in both groups.The degree of improvement for every index was substantially greater in the research group than in the control group(P<0.05).Following treatment,the AFP,GPC-3,and AFP-L3 levels in both groups decreased,with the research group having significantly lower levels than the control group(P<0.05).The incidence of diarrhea,rash,nausea and vomiting,and fatigue in the research group was significantly greater than that in the control group(P<0.05).The 1-,2-,and 3-year survival rates of the research group(94.00%,84.00%,and 72.00%,respectively)were significantly greater than those of the control group(80.00%,64.00%,and 40.00%,respectively;P<0.05).Significant differences were observed between the survival group and the non-surviving group in terms of Child-Pugh grade,history of hepatitis,number of tumors,tumor size,use of sorafenib,stage of liver cancer,histological differentiation,history of splenectomy and other basic data(P<0.05).Logistic regression analysis demonstrated that high Child-Pugh grade,tumor size(6–10 cm),history of hepatitis,no use of sorafenib,liver cancer stage IIIC,and previous splenectomy were independent risk factors for poor prognosis in patients with liver cancer complicated with portal hypertension(P<0.05).CONCLUSION Patients suffering from liver cancer complicated by portal hypertension benefit from the combination of RFA and sorafenib therapy because it effectively restores liver function and increases survival rates.The prognosis of patients suffering from liver cancer complicated by portal hypertension is strongly associated with factors such as high Child-Pugh grade,tumor size(6-10 cm),history of hepatitis,lack of sorafenib use,liver cancer at stage IIIC,and prior splenectomy. 展开更多
关键词 radiofrequency ablation SORAFENIB Liver cancer Portal hypertension EFFICACY Prognosis analysis
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New Rotative Radiofrequency Technology: A Multicenter Retrospective Study on Efficacy and Safety
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作者 José Antonio Ferrández Martínez Gregorio Viera Mármol +5 位作者 Fabrizio Vignoli Joanet Perera Agustin Blanch Mara Suárez Alicia Robledo Jorge Reyna Vargas Lamas 《Journal of Cosmetics, Dermatological Sciences and Applications》 2024年第1期69-83,共15页
Background: Non-ablative radiofrequency (RF) technology is widely used for the treatment of signs of aging, skin laxity, localized fat and cellulite. However, many RF devices suffer from technical limitations that mak... Background: Non-ablative radiofrequency (RF) technology is widely used for the treatment of signs of aging, skin laxity, localized fat and cellulite. However, many RF devices suffer from technical limitations that make the results highly dependent on the user’s experience or clinical limitations that compromise safety, efficacy and comfort. Objective: To evaluate the efficacy and safety of a novel semi-automatic non-ablative RF device for skin tightening, body shaping and cellulite reduction. Materials and methods: A retrospective multicenter study was performed using a novel rotative RF device with temperature and impedance control (Sculpt&Shape<sup>®</sup>, Sinclair, Spain). 58 subjects underwent a minimum of 4 treatments every 1-2 weeks. A total of 120 treatments (56.7% body and 43.3% facial) and 1034 sessions were performed. Efficacy was evaluated by 3 researchers using the Global Aesthetic Improvement Scale (GAIS) and anthropometric measurements were collected. Subject and practitioner satisfaction were recorded. Safety was evaluated by analyzing the perception of pain during the treatment and the side and adverse effects immediately after treatment and over the next 48 hours. Results: Between 25% and 50% improvement was achieved according to the GAIS. Statistically significant (p < 0.01) abdominal fold reduction of 5.1 mm and circumference reduction of 32.0 mm, 16.4 mm and 13.9 mm were recorded for the abdomen, legs and arms, respectively. 77.5% of subjects and 94.9% of practitioners were either satisfied or very satisfied. Minor adverse effects were found in 0.97% of the sessions. Conclusion: This novel semi-automatic rotative RF device has been found to provide treatments that are effective, safe and comfortable for both practitioners and subjects. . 展开更多
关键词 Rotative radiofrequency rf CELLULITE Skin Tightening Body Shaping
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From Simulation to Reality: A Comprehensive Study on the Efficacy of a Rotating Monopolar and Bipolar Radiofrequency System through In-Silico Modeling and Pre-Clinical and Clinical Validation
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作者 Gregorio Viera Mármol Ana Lorena Urbano Bojorge +2 位作者 Alicia Robledo Jorge José Antonio Ferrández Martínez Olalla Calvo Lozano 《Journal of Biomedical Science and Engineering》 2024年第6期107-128,共22页
Background: Skin aging is an unavoidable process aggravated by environmental agents. Among other energy devices, non-invasive radiofrequency (RF) technology is widely used for skin tightening and body contouring as it... Background: Skin aging is an unavoidable process aggravated by environmental agents. Among other energy devices, non-invasive radiofrequency (RF) technology is widely used for skin tightening and body contouring as it is simpler and more affordable than other technologies that also minimize pain and side-effects. However, most of the current RF devices do not provide automatic skin temperature control and it is difficult to achieve controlled, deep, and harmless thermal increase, so treatment performance and safety is dependent on the operator’s movements and expertise. Objective: To show the potential of numerical simulations for optimizing the design of monopolar and bipolar RF electrodes that are capable of providing homogeneous, deep and controlled heating. Materials and methods: In-silico models were developed and analyzed using Comsol Multiphysics software to simulate the RF effect produced in tissue by rotating monopolar and bipolar electrodes with different geometries from the Sculpt & Shape RF device (Sinclair, Spain), operating at frequencies of 0.5 and 1 MHz. Ex-vivo and in-vivo proof-of-concept tests were carried out to validate the simulations. Finally, treatments were performed on 16 subjects and a total of 78 body areas to assess the clinical results generated by the RF electrodes for skin tightening and body contouring. Results: In-silico studies emulated the superficial and deep dispersion of heat due to the release of RF energy into human skin tissue. The rotating electrodes (monopolar and bipolar) and the selected RF frequency (0.5 and 1 MHz) determined the homogeneity of the thermal distribution, the penetration depth (between 4.37 mm and 25.0 mm) and the heating dynamics (between 30 and 100 seconds to reach the target skin temperature), which were confirmed by ex-vivo and in-vivo tests. In addition, real treatments on facial and body areas using skin temperatures of between 43˚C and 44˚C showed consistent results with good clinical efficacy for skin tightening, circumference reduction and cellulite reduction, with no adverse effects and high subject satisfaction. Conclusions: New monopolar and bipolar RF electrodes with rotating technology have been designed and optimized using numerical simulations. The use of in-silico studies and accurate models that reproduce the thermal behavior of human biological tissues can be used to better understand RF devices and to develop superior, efficient, and safer products more quickly. 展开更多
关键词 Comsol Multiphysics Simulations radiofrequency Skin Tightening Fat Reduction Body Contouring CELLULITE
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Percutaneous transhepatic cholangiography:An effective option for endo-biliary radiofrequency ablation before stent insertion in unresectable biliary cancer?
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作者 Dimitrios S Karagiannakis 《World Journal of Clinical Cases》 SCIE 2024年第30期6413-6416,共4页
Biliary cancer is a highly aggressive disease that is typically diagnosed at advanced stages when surgical removal is no longer an option.In these cases,palliative care and mechanical widening of the blocked biliary s... Biliary cancer is a highly aggressive disease that is typically diagnosed at advanced stages when surgical removal is no longer an option.In these cases,palliative care and mechanical widening of the blocked biliary system are preferred.The insertion of a stent is often necessary to prevent the recurrence of blockages caused by cancer progression.Prior to stent placement,endo-biliary radiofrequency ablation(EB-RFA)appears to result in longer-lasting stent effectiveness without increasing the risk of severe complications.However,its impact on overall survival is not yet clear.Additionally,while endoscopic retrograde cholangiopancreatography is the most common method for performing EB-RFA,percutaneous transhepatic cholangiodrainage seems to be a safe and potentially more efficient alternative,particularly for long,angulated,or significantly narrowed bile ducts. 展开更多
关键词 Biliary cancer CHOLANGIOCARCINOMA Pancreatic cancer Percutaneous transhepatic cholangiodrainage radiofrequency ablation
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Analysis of alkaline phosphatase and γ-glutamyltransferase after radiofrequency ablation of primary liver cancer: A retrospective study
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作者 Wen-Yu Huang Sheng Zheng +7 位作者 Dan Zhu Ying-Lang Zeng Juan Yang Xue-Li Zeng Pei Liu Shun-Ling Zhang Ming Yuan Zhi-Xia Wang 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第9期2860-2869,共10页
BACKGROUND Changes in alkaline phosphatase(ALP)andγ-glutamyltransferase(GGT)levels in patients with primary liver cancer(PLC)after radiofrequency ablation(RFA).Hepatocellular carcinoma is a malignant tumor with high ... BACKGROUND Changes in alkaline phosphatase(ALP)andγ-glutamyltransferase(GGT)levels in patients with primary liver cancer(PLC)after radiofrequency ablation(RFA).Hepatocellular carcinoma is a malignant tumor with high incidence worldwide.As a common local treatment,RFA has attracted much attention for its efficacy and influence on liver function.AIM To investigate the effect of serum ALP and GGT levels on the prognosis of patients with PLC treated by RFA.METHODS The preoperative clinical data of 165 patients who were pathologically or clinically diagnosed with PLC and who received RFA in our hospital between October 2018 and June 2023 were collected.The chi-square test was used to compare the data between groups.The Kaplan-Meier method and Cox regression were used to analyze the associ-ations between serum ALP and GGT levels and overall survival,progression-free survival(PFS)and clinical characteristics of patients before treatment.RESULTS The 1-year survival rates of patients with normal(≤135 U/L)and abnormal(>135 U/L)serum ALP before treatment were 91%and 79%,respectively;the 2-year survival rates were 90%and 68%,respectively;and the 5-year survival rates were 35%and 18%,respectively.The difference between the two groups was statistically significant(P=0.01).Before treatment,the 1-year survival rates of patients with normal serum GGT levels(≤45 U/L)and abnormal serum GGT levels(>45 U/L)were 95%and 87%,the 2-year survival rates were 85%and 71%,and the 5-year survival rates were 37%and 21%,respectively.The difference between the two groups was statist-ically significant(P<0.001).Serum ALP[hazard ratio(HR)=1.766,95%confidence interval(95%CI):1.068-2.921,P=0.027]and GGT(HR=2.312,95%CI:1.367-3.912,P=0.002)is closely related to the overall survival of PLC patients after RF ablation and is an independent prognostic factor.The 1-year PFS rates were 72%and 50%,the 2-year PFS rates were 52%and 21%,and the 5-year PFS rates were 14%and 3%,respectively.The difference between the two groups was statistically significant(P<0001).The 1-year PFS rates were 81%and 56%in patients with normal and abnormal serum GGT levels before treatment,respectively;the 2-year PFS rates were 62%and 35%,respectively;and the 5-year PFS rates were 18%and 7%,respectively,with statistical significance between the two groups(P<0.001).The serum ALP concentration(HR=1.653,95%CI:1.001-2.729,P=0.049)and GGT(HR=1.949,95%CI:1.296-2.930,P=0.001)was closely associated with PFS after RFA in patients with PLC.The proportion of male patients with abnormal ALP levels is high,the Child-Pugh grade of liver function is poor,and the incidence of ascites is high.Among GGT-abnormal patients,the Child-Pugh grade of liver function was poor,the tumor stage was late,the proportion of patients with tumors≥5 cm was high,and the incidence of hepatic encephalopathy was high.CONCLUSION Serum ALP and GGT levels before treatment can be used to predict the prognosis of patients with PLC after RFA,and they have certain guiding significance for the long-term survival of patients with PLC after radiofrequency therapy. 展开更多
关键词 Alkaline phosphatase γ-glutamyltransferase radiofrequency ablation Primary liver cancer Retrospective study
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Severe hypoxemia after radiofrequency ablation for atrial fibrillation in palliatively repaired tetralogy of Fallot: A case report
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作者 Zhi-Hang Li Lian Lou +3 位作者 Yu-Xiao Chen Wen Shi Xuan Zhang Jian Yang 《World Journal of Cardiology》 2024年第3期161-167,共7页
BACKGROUND Patients with tetralogy of Fallot(TOF)often have arrhythmias,commonly being atrial fibrillation(AF).Radiofrequency ablation is an effective treatment for AF and does not usually cause severe postoperative h... BACKGROUND Patients with tetralogy of Fallot(TOF)often have arrhythmias,commonly being atrial fibrillation(AF).Radiofrequency ablation is an effective treatment for AF and does not usually cause severe postoperative hypoxemia,but the risk of complications may increase in patients with conditions such as TOF.CASE SUMMARY We report a young male patient with a history of TOF repair who developed severe hypoxemia after radiofrequency ablation for AF and was ultimately confirmed to have a new right-to-left shunt.The patient subsequently underwent atrial septal occlusion and eventually recovered.CONCLUSION Radiofrequency ablation may cause iatrogenic atrial septal injury;thus possible complications should be predicted in order to ensure successful treatment and patient safety. 展开更多
关键词 Atrial fibrillation radiofrequency ablation Tetralogy of Fallot Right-to-left shunt HYPOXEMIA Medical decision Case report
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Efficacy and safety of B-ultrasound-guided radiofrequency ablation in the treatment of primary liver cancer: Systematic review and metaanalysis
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作者 Xiong Zhang Hong-Yi Zhu Ming Yuan 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第9期2986-2995,共10页
BACKGROUND Primary liver cancer is one of the most lethal malignancies in the world.Tradi-tional treatment methods have limitations in terms of efficacy and safety.Ra-diofrequency ablation(RFA)guided by B-ultrasound,a... BACKGROUND Primary liver cancer is one of the most lethal malignancies in the world.Tradi-tional treatment methods have limitations in terms of efficacy and safety.Ra-diofrequency ablation(RFA)guided by B-ultrasound,as a minimally invasive treatment,has attracted increasing attention in the treatment of primary liver cancer in recent years.AIM To study the efficacy and safety of RFA were compared with those of traditional surgery(TS)for treating small liver cancer.METHODS At least 2 people were required to search domestic and foreign public databases,including foreign databases such as EMBASE,PubMed and the Cochrane Library,and Chinese databases such as the China National Knowledge Infrastructure database,China Biomedical Literature database,Wanfang database and VIP database.Controlled trials of RFA vs conventional surgery for small liver cancer were retrieved from January 2008 to January 2023.They were screened and eva-luated according to the quality evaluation criteria in the Cochrane Handbook of Systematic Reviews.The meta-analysis was performed using RevMan 5.3 soft-ware.RESULTS A total of 10 studies were included in this study,including 1503 patients in the RFA group and 1657 patients in the surgery group.The results of the meta-ana-lysis showed that there was no significant difference in 1-year overall survival between the two groups(P>0.05),while the 3-year and 5-year overall survival rates and 1-year,3-year and 5-year tumor-free survival rates in the surgery group were greater than those in the RFA group(P<0.05).In terms of complications,the incidence of complications in the RFA group was lower than that in the surgery group(P<0.05).CONCLUSION In terms of long-term survival,TS is better than RFA for small liver cancer patients.However,RFA has fewer complications and is safer. 展开更多
关键词 Survival prognosis Small liver cancer radiofrequency ablation Traditional surgical resection META-ANALYSIS
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Radiofrequency ablation combined with transcatheter arterial chemoembolization for recurrent liver cancer
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作者 Jin-You Guo Li-Li Zhao +2 位作者 Hui-Jun Cai Hui Zeng Wei-Dong Mei 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第6期1756-1764,共9页
BACKGROUND The recurrence rate of liver cancer after surgery is high.Radiofrequency ablation(RFA)combined with transcatheter arterial chemoembolization(TACE)is an effective treatment for liver cancer;however,its effic... BACKGROUND The recurrence rate of liver cancer after surgery is high.Radiofrequency ablation(RFA)combined with transcatheter arterial chemoembolization(TACE)is an effective treatment for liver cancer;however,its efficacy in recurrent liver cancer remains unclear.AIM To investigate the clinical effect of TACE combined with RFA in the treatment of recurrent liver cancer.METHODS Ninety patients with recurrent liver cancer were divided into 2 groups according to treatment plan:Control(RFA alone);and experimental[TACE combined with RFA(TACE+RFA)].The incidence of increased alanine aminotransferase levels,complications,and other indices were compared between the two groups before and after the procedures.RESULTS One month after the procedures,the short-term efficacy rate and Karnofsky Performance Status scores of the experimental group were significantly higher than those of the control group(P<0.05).Alpha-fetoprotein(AFP)and total bilirubin levels were lower than those in the control group(P<0.05);The overall response rate was 82.22%and 66.67%in the experimental and control groups,respectively;The disease control rate was 93.33%and 82.22%in the experimental and control groups,respectively,the differences are statistically significant(P<0.05).And there were no statistical differences in complications between the two groups(P>0.05).CONCLUSION TACE+RFA was effective for the treatment of recurrent liver cancer and significantly reduced AFP levels and improved various indices of liver function. 展开更多
关键词 Transcatheter arterial chemoembolization radiofrequency ablation Recurrent liver cancer Clinical efficacy Overall response rate Disease control rate
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Numerical simulation and performance analysis of the radiofrequency inductive cathode
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作者 乔宽 程谋森 +4 位作者 张帆 杨雄 郭大伟 杨云天 丁振伟 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第2期179-193,共15页
The radiofrequency(RF) inductive cathode has great prospects in space missions with long mission cycles, large speed increments, and rapid response requirements as the main electron source and neutralizer in Hall thru... The radiofrequency(RF) inductive cathode has great prospects in space missions with long mission cycles, large speed increments, and rapid response requirements as the main electron source and neutralizer in Hall thrusters and ion thrusters. This paper proposes a comprehensive multi-physics RF inductive cathode model in which the RF electromagnetic field, electrostatic field for extracting electrons, flow field, plasma transport and electrochemical reaction process are all accounted for. Each physical field mentioned above can form a closed partial differential equation. The two-dimensional finite element code COMSOL is used to solve the multi-physics model. With this model, the formation process of the anode spot is exhibited and demonstrates the non-bipolar flow theory in practice. The simulation results demonstrate that the current jump in the RF inductive cathode is caused by the anode spot. Furthermore, the influences of preset discharge parameters such as RF power, bias voltage and actuating gas flow as well as structural parameters like the coil structure, discharge chamber size and ion collector area, emission hole size, distance between the anode target and the emission hole etc on the cathode performance are investigated, and some important optimal parameters are proposed. 展开更多
关键词 rf inductive cathode electron current anode spot
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基于RF-SFLA-SVM的装配式建筑高空作业工人不安全行为预警
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作者 王军武 何娟娟 +3 位作者 宋盈辉 刘一鹏 陈兆 郭婧怡 《中国安全科学学报》 CAS CSCD 北大核心 2024年第3期1-8,共8页
为有效预警装配式建筑高空作业工人不安全行为的发生趋势或状态,增强对装配式建筑工人不安全行为(PBWUBs)的管控,采用随机森林(RF)-混合蛙跳算法(SFLA)-支持向量机(SVM)模型,开展工人不安全行为预警研究。首先,采用SHEL模型分析处于高... 为有效预警装配式建筑高空作业工人不安全行为的发生趋势或状态,增强对装配式建筑工人不安全行为(PBWUBs)的管控,采用随机森林(RF)-混合蛙跳算法(SFLA)-支持向量机(SVM)模型,开展工人不安全行为预警研究。首先,采用SHEL模型分析处于高空作业危险中的PBWUBs的影响因素,并通过RF确定关键预警指标;然后,采用SFLA对SVM的参数进行寻优改进;最后,利用RF-SFLA-SVM预警高空作业PBWUBs,提出应对措施,并与其他预警模型对比。研究结果表明:基于RF-SFLA-SVM预警高空作业PBWUBs,准确率最高,为91.67%,与其他模型的预警性能相比,最高提升14%。研究结果可为高空作业PBWUBs的防控提供参考。 展开更多
关键词 随机森林(rf) 蛙跳算法(SFLA) 支持向量机(SVM) 装配式建筑 高空作业 不安全行为
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基于DBSCAN-RF洪水分类的洪水预报应用研究 被引量:1
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作者 甘甜 郑英 +3 位作者 蒋云钟 赵红莉 贺君彦 段浩 《水利水电技术(中英文)》 北大核心 2024年第3期77-89,共13页
【目的】洪水分类预报能有效提高洪水预报准确性,为防灾减灾工作提供科学依据。【方法】针对分类因子和分类算法优选问题,以海河流域徒骇河宫家闸上游为例进行研究,(1)充分考虑产汇流影响因素与洪水特征,选取洪峰流量、洪水总量、时段... 【目的】洪水分类预报能有效提高洪水预报准确性,为防灾减灾工作提供科学依据。【方法】针对分类因子和分类算法优选问题,以海河流域徒骇河宫家闸上游为例进行研究,(1)充分考虑产汇流影响因素与洪水特征,选取洪峰流量、洪水总量、时段洪量、洪水历时、起历时、落历时、峰度、偏度、涨水仰角、落水仰角、C_(s)、C_(v)、前3 d面雨量、前10 d面雨量、累计面雨量及最大面雨量等16维分类因子,使用主成分投影法(Principal Component Analysis,PCA)对分类因子降维提高计算效率;(2)基于密度聚类(Density-Based Spatial Clustering of Applications with Noise,DBSCAN)-随机森林(Random Forest,RF)算法进行洪水分类,减少对分类先验知识的依赖,提高了分类精度;(3)在徒骇河流域进行了方法应用,选择适用于半干旱半湿润地区的超渗-蓄满同时作用的产流模型及单位线汇流模型进行洪水分类预报研究,分别针对各类洪水进行模型率定。【结果】结果表明:轮廓系数为0.7015,表明DBSCAN算法聚类效果理想,基于RF算法的洪水分类准确率为91.67%,分类效果理想;经洪水分类预报,NSE系数均高于0.8,分类预报结果优于直接预报。【结论】结果说明:基于DBSCAN-RF洪水分类的洪水预报能较好地反映研究区域洪水演进过程,为研究区域洪水预报及防灾减灾工作提供依据。 展开更多
关键词 历史洪水 洪水分类 洪水预报 密度聚类(DBSCAN) 随机森林(rf)
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基于RF-RNN模型的DNS隐蔽信道检测方法
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作者 冯燕茹 《信息与电脑》 2024年第3期158-160,共3页
为提高检测隐蔽信道的灵敏度,提出一种基于随机森林(Random Forest,RF)和循环神经网络(Recurrent Neural Network,RNN)的域名系统(Domain Name System,DNS)隐蔽信道检测方法。该方法采用域名检测作为主要手段,使用RF模型对域名进行分类... 为提高检测隐蔽信道的灵敏度,提出一种基于随机森林(Random Forest,RF)和循环神经网络(Recurrent Neural Network,RNN)的域名系统(Domain Name System,DNS)隐蔽信道检测方法。该方法采用域名检测作为主要手段,使用RF模型对域名进行分类,通过深度学习方法挖掘更高阶的特征表示。实验结果表明,与单一模型相比,该方法在检测准确性和健壮性方面均取得了显著提升。 展开更多
关键词 域名系统(DNS) 随机森林(rf) 循环神经网络(RNN)
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RIS辅助的混合RF/FSO系统物理层安全性能分析
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作者 赵辉 万辉 +1 位作者 李静 马薇雯 《光通信研究》 北大核心 2024年第2期12-20,共9页
【目的】针对自由空间光(FSO)链路和射频(RF)链路的保密信息容易被外部窃听者窃听的问题,为提升混合RF/FSO通信系统的保密性能,同时考虑到实际工程中FSO链路往往无法满足视距条件且不同天线分支之间会由于收发模块小型化产生相关性,需... 【目的】针对自由空间光(FSO)链路和射频(RF)链路的保密信息容易被外部窃听者窃听的问题,为提升混合RF/FSO通信系统的保密性能,同时考虑到实际工程中FSO链路往往无法满足视距条件且不同天线分支之间会由于收发模块小型化产生相关性,需要对可重构智能表面(RIS)辅助的混合RF/FSO系统的安全性能进行研究,以得到系统安全性能与RIS部署位置和天线相关性程度等参数的关系。【方法】文章考虑单个窃听者,分别针对RF和FSO链路进行窃听,RF链路服从任意相关的Nakagami-m分布,FSO链路服从Gamma-Gamma分布。采用解码转发协议,推导得到了两种窃听场景下通信系统的安全中断概率(SOP)和严格正安全容量概率(SPSC)的闭合表达式,并对SOP进行了渐近分析。此外还利用Matlab软件进行了仿真实验,通过蒙特卡洛仿真来验证所推导公式的准确性。【结果】仿真结果表明,将RIS部署在靠近接收端的位置可以降低系统的SOP,RF主信道的信道质量与窃听信道相比较好时,天线相关性程度的增加会使系统的SOP上升。【结论】RIS辅助的FSO链路相比RF链路具有更好的安全性,虽然多天线分集技术能够有效提高系统的安全性能,但是类似指向误差和大气湍流引起的衰落,天线相关性也会对系统的安全性能造成损害,通过降低天线相关性程度能有效提升系统的安全性。 展开更多
关键词 光通信 混合射频/自由空间光通信系统 可重构智能表面 天线相关性 物理层安全
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基于RF-GWO的水利工程地质渗透系数智能反演分析
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作者 雷艳 温立峰 +1 位作者 赵明仓 殷乔刚 《水资源与水工程学报》 CSCD 北大核心 2024年第2期139-148,共10页
地质渗透系数是准确分析水利工程渗流的关键参数。针对传统反演方法计算效率低、精度差的问题,采用有限元正演模型和正交试验设计构建渗透系数反演样本集,建立了基于随机森林(RF)算法的渗流计算代理模型;在此基础上,引入灰狼优化(GWO)算... 地质渗透系数是准确分析水利工程渗流的关键参数。针对传统反演方法计算效率低、精度差的问题,采用有限元正演模型和正交试验设计构建渗透系数反演样本集,建立了基于随机森林(RF)算法的渗流计算代理模型;在此基础上,引入灰狼优化(GWO)算法,提出了基于RF-GWO的渗透系数智能反演方法,并以Z抽水蓄能电站为研究案例进行了验证。结果表明:RF模型对各钻孔水位预测结果均接近实测值,性能优于CART和BP模型;GWO可搜寻到地质最佳渗透系数,钻孔水位反演结果合理,相对误差最大为0.42%,精度满足工程要求,计算的天然渗流场分布形态也符合一般山体渗流场分布规律。建立的反演模型能够快速准确地推断工程区地层渗透系数,具有实际工程应用价值。 展开更多
关键词 地质渗透系数 反演分析 正交试验设计 随机森林 灰狼优化
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基于RF-GA的热磨机生产参数优化方法
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作者 陈光伟 杨凯 +2 位作者 许威 黄鹤飞 王丙军 《林业机械与木工设备》 2024年第6期42-48,共7页
热磨机是纤维板生产中最重要的设备之一;热磨机的综合能耗在纤维板生产的整体能源消耗中占比显著,优化生产参数以降低热磨机能耗一直是纤维板生产的要求之一。以华北某纤维板企业采集的数据为依据,针对影响比能耗(SEC)和纤维质量(QF)的... 热磨机是纤维板生产中最重要的设备之一;热磨机的综合能耗在纤维板生产的整体能源消耗中占比显著,优化生产参数以降低热磨机能耗一直是纤维板生产的要求之一。以华北某纤维板企业采集的数据为依据,针对影响比能耗(SEC)和纤维质量(QF)的多个生产参数,用粒子群算法优化的BP神经网络、支持向量机(SVM)和随机森林(RF)建立比能耗和纤维质量预测模型,经对比确定最佳比能耗和纤维质量预测模型;后基于最佳预测模型构建生产参数优化模型,采用遗传算法(GA)对其求解得到最佳生产参数,以此提出基于RF-GA模型的热磨机生产参数优化方法。结果表明,热磨机各生产参数之间存在较强耦合关系,且与比能耗和纤维质量为非线性关联;粒子群算法对机器学习算法中超参数的优化是必要的,可以有效降低机器学习算法误差;选取5组不同纤维质量下的数据,采用建立的热磨机生产参数优化方法优化后,比能耗平均下降6.9kW·h/t、降幅为5.22%。该研究验证了RF-GA热磨机生产参数优化方法的可行性,能够应用于生产参数的优化,有效地实现节能降耗的目标,并为热磨机生产参数的设定提供依据。 展开更多
关键词 热磨机 节能 优化 生产参数 粒子群算法 rf-GA
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基于VPNRS-RF的飞机液压系统故障诊断模型
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作者 李耀华 王签签 《机械设计与制造》 北大核心 2024年第2期255-260,共6页
针对飞机液压系统故障诊断特征值冗余难以精准获取和准确率不高的问题,提出一种基于变精度邻域粗糙集(Variable Precision Neighborhood Rough Set,VPNRS)和随机森林(Random Forest,RF)相结合的特征选择算法,并以此为基础建立飞机液压... 针对飞机液压系统故障诊断特征值冗余难以精准获取和准确率不高的问题,提出一种基于变精度邻域粗糙集(Variable Precision Neighborhood Rough Set,VPNRS)和随机森林(Random Forest,RF)相结合的特征选择算法,并以此为基础建立飞机液压系统故障诊断模型。VPNRS-RF算法主要是利用随机森林算法分别对变精度邻域和模糊熵粗糙集约简后的特征进行重要度排序,再次筛选后确定最优特征子集,使用最优特征子集对在线贯序极限学习机(OSELM)分类模型进行训练,从而提高故障信息获取准确率。最后以飞机起落架收放系统为例进行仿真研究,验证了VPNRS-RFOSELM模型的优越性。 展开更多
关键词 VPNRS-rf OSELM 液压系统 特征选择 最优特征子集
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多尺度数据条件下基于优化RF算法的工程机械可靠性仿真
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作者 张丽 马利祥 《佳木斯大学学报(自然科学版)》 CAS 2024年第4期83-87,共5页
工程机械是建筑工程的关键设备,其可靠性的高低直接影响到工程的生产效率,为了给项目工程提供可靠性较高的机械设备,提出多尺度数据条件下基于优化RF算法的工程机械可靠性分析方法。构建工程机械设备等效模型,确定工程机械设备的组成结... 工程机械是建筑工程的关键设备,其可靠性的高低直接影响到工程的生产效率,为了给项目工程提供可靠性较高的机械设备,提出多尺度数据条件下基于优化RF算法的工程机械可靠性分析方法。构建工程机械设备等效模型,确定工程机械设备的组成结构与材料,模拟工程机械设备工作流程,确定可靠性影响因素。采集工程机械设备多尺度数据,利用优化RF算法,通过决策树构建、特征提取等步骤,识别工程机械设备工作状态。计算工程机械可靠性指标的具体取值,实现工程机械的可靠性分析。通过仿真测试实验得出结论:与传统分析方法相比,优化设计方法的机械可靠性分析误差降低了0.033,通过可靠性分析方法的应用能够有效提升工程产品的生产合格率,由此证明优化设计方法在分析精度和应用性能方面具有明显优势。 展开更多
关键词 多尺度数据条件 优化rf算法 工程机械设备 可靠性分析
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