The dynamic analysis and optimal design of reactive extraction are challenging due to high nonlinearity of model equations and tough decision of judging criteria. In this work, a dynamic rate-based method is developed...The dynamic analysis and optimal design of reactive extraction are challenging due to high nonlinearity of model equations and tough decision of judging criteria. In this work, a dynamic rate-based method is developed on g PROMS platform to get easy access to the solutions of reactive extraction with phase splitting. Based on rigorous criteria, dynamic analysis from initial state to final equilibrium(e.g., evolution of phase composition, mass transfer rate and reaction rate) and optimal design of operating conditions(e.g., extractant dosage and feed molar ratio) are achieved. To illustrate the method, the esterification of n-hexyl acetate is taken as an example. The approach proves to be reliable in the analysis and optimization of the exemplified system, which provides instructive reference for further process design and simulation of reactive extraction.展开更多
目的:对中国脑卒中病人营养风险的检出率进行系统评价与Meta分析。方法:计算机检索中国知网(CNKI)、维普数据库(VIP)、万方数据库(WanFang Database)、中国生物医学文献数据库(CBM)、PubMed、EMbase、Web of Science,收集从建库至2023年...目的:对中国脑卒中病人营养风险的检出率进行系统评价与Meta分析。方法:计算机检索中国知网(CNKI)、维普数据库(VIP)、万方数据库(WanFang Database)、中国生物医学文献数据库(CBM)、PubMed、EMbase、Web of Science,收集从建库至2023年4月30日关于中国脑卒中病人营养风险检出率的横断面研究。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险,采用Stata 15.1软件进行Meta分析。结果:共纳入35项横断面研究,涉及9 616例脑卒中病人,其中3 975例存在营养风险,中国脑卒中病人营养风险总检出率为42.5%[95%CI(37.7%,47.4%)],亚组分析结果显示,男性和女性脑卒中病人营养风险检出率分别为50.0%、53.2%;60岁以下、60岁及以上脑卒中病人营养风险检出率分别为27.4%、47.7%;就脑卒中类型而言,缺血性脑卒中和出血性脑卒中病人营养风险检出率分别为50.1%、52.1%;首次发生脑卒中病人营养风险检出率(45.1%)低于有脑卒中病史病人(57.2%);合并吞咽困难脑卒中病人营养风险检出率(60.5%)高于未合并吞咽困难的脑卒中病人(34.9%);使用营养风险筛查2002、微型营养评估表、微型营养评价精法及营养不良通用筛查工具检测出脑卒中病人营养风险发生率分别为45.3%、23.3%、41.3%、42.3%。结论:我国脑卒中病人营养风险的检出率较高,不同亚组间脑卒中病人营养风险检出率存在差异。展开更多
基金Supported by the National Natural Science Foundation of China(21776074,21576081,2181101120).
文摘The dynamic analysis and optimal design of reactive extraction are challenging due to high nonlinearity of model equations and tough decision of judging criteria. In this work, a dynamic rate-based method is developed on g PROMS platform to get easy access to the solutions of reactive extraction with phase splitting. Based on rigorous criteria, dynamic analysis from initial state to final equilibrium(e.g., evolution of phase composition, mass transfer rate and reaction rate) and optimal design of operating conditions(e.g., extractant dosage and feed molar ratio) are achieved. To illustrate the method, the esterification of n-hexyl acetate is taken as an example. The approach proves to be reliable in the analysis and optimization of the exemplified system, which provides instructive reference for further process design and simulation of reactive extraction.
基金the financial supports from the National Key Laboratory of Science and Technology for National Defence on High-Strength Lightweight Structural Materials of China(No.20190104)State Key Laboratory of High-Performance Complex Manufacturing of Central South University,China(No.ZZYJKT2020-03)the National Key Research and Development Program of China(No.2016YFB0300801)。
