Diffusion tensor imaging plays an important role in the accurate diagnosis and prognosis of spinal cord diseases. However, because of technical limitations, the imaging sequences used in this technique cannot reveal t...Diffusion tensor imaging plays an important role in the accurate diagnosis and prognosis of spinal cord diseases. However, because of technical limitations, the imaging sequences used in this technique cannot reveal the fine structure of the spinal cord with precision. We used the readout segmentation of long variable echo-trains（RESOLVE） sequence in this cross-sectional study of 45 healthy volunteers aged 20 to 63 years. We found that the RESOLVE sequence significantly increased the resolution of the diffusion images and improved the median signal-to-noise ratio of the middle（C4–6） and lower（C7–T1） cervical segments to the level of the upper cervical segment. In addition, the values of fractional anisotropy and radial diffusivity were significantly higher in white matter than in gray matter. Our study verified that the RESOLVE sequence could improve resolution of diffusion tensor imaging in clinical applications and provide accurate baseline data for the diagnosis and treatment of cervical spinal cord diseases.展开更多
目的探讨脊髓型颈椎病诊断中3.0T高清弥散多次激发弥散加权成像(readout segmentation of long variable echo-trains,RESOLVE-DWI)的应用价值。方法选取本院收治的脊髓型颈椎病患者60例为观察组,于同期本院接收的健康体检者中选取60例...目的探讨脊髓型颈椎病诊断中3.0T高清弥散多次激发弥散加权成像(readout segmentation of long variable echo-trains,RESOLVE-DWI)的应用价值。方法选取本院收治的脊髓型颈椎病患者60例为观察组,于同期本院接收的健康体检者中选取60例为对照组,均采用3.0T高清弥散RESOLVE-DWI序列进行检查,对比分析两组检查情况。结果观察组病变或受压部位的ADC值是(1.35±0.13)×10^-3 mm^2/s,比对照组的(1.01±0.03)×10^-3 mm^2/s及观察组中相对正常部位的(1.02±0.02)×10^-3 mm^2/s高,差异有统计学意义(P<0.05);RESOLVE-DWI序列图像质量评分较T 2WI高,差异有统计学意义(P<0.05);RESOLVE-DWI的敏感性为96.7%,特异性为95.0%,分别较T 2WI的敏感性91.7%、特异性88.3%高,差异有统计学意义(P<0.05)。结论3.0T高清弥散RESOLVE-DWI序列图像质量高,可对脊髓、解剖结构进行清晰显示,应用于脊髓型颈椎病诊断中准确率、敏感性高,值得选用。展开更多
文摘Diffusion tensor imaging plays an important role in the accurate diagnosis and prognosis of spinal cord diseases. However, because of technical limitations, the imaging sequences used in this technique cannot reveal the fine structure of the spinal cord with precision. We used the readout segmentation of long variable echo-trains（RESOLVE） sequence in this cross-sectional study of 45 healthy volunteers aged 20 to 63 years. We found that the RESOLVE sequence significantly increased the resolution of the diffusion images and improved the median signal-to-noise ratio of the middle（C4–6） and lower（C7–T1） cervical segments to the level of the upper cervical segment. In addition, the values of fractional anisotropy and radial diffusivity were significantly higher in white matter than in gray matter. Our study verified that the RESOLVE sequence could improve resolution of diffusion tensor imaging in clinical applications and provide accurate baseline data for the diagnosis and treatment of cervical spinal cord diseases.
