Objective: To evaluate, in a comprehensive way, mesh and mesh free SUI treatment results obtained in a single center. The present study addresses the efficacy and safety of a novel surgical technique. Material & M...Objective: To evaluate, in a comprehensive way, mesh and mesh free SUI treatment results obtained in a single center. The present study addresses the efficacy and safety of a novel surgical technique. Material & Methods: Adult female SUI patients, 184 in total, were divided within a sequential manner into two groups to be treated for SUI either with or without mesh insertion during a surgical intervention. In this novel procedure, a vertical vaginal incision from the urethra towards the bladder bottom is made and closed transversely. After the intervention the patients revisited the clinic at the 6th month. Results: 81 patients in mesh and 83 in the mesh free group completed the 2-year follow up. Based on the pad tests conducted at the end of 24-month follow up, 82% of the patients in the mesh free group and 85% in the mesh group were considered as successful if the pad test resulted with ≤2 gram. Cystocele of Grade I or II was also treated in 69 patients within the same single surgical procedure. Conclusion: The surgical outcomes of the mesh and mesh-free group were almost the same. However, though the cure rate of the mesh group was higher, it was not statistically significant. Adverse events were more frequent in the mesh group due to mesh presence.展开更多
AIM: To evaluate the frequency of use of various treatment modalities for Budd-Chiari syndrome (BCS) in China by conducting a preliminary survey of relevant literature.
A wide range of welding and surface treatment processes involve the use of a heat source which is moving at a constant speed over the component. The numerical simulation of such processes implies a transient analysis ...A wide range of welding and surface treatment processes involve the use of a heat source which is moving at a constant speed over the component. The numerical simulation of such processes implies a transient analysis using a very refined mesh in order to follow properly the path of the heat source. The 3D-mesh size can be very large if one consider the welds length or the heat-treated surface size in industrial components. To reduce the computational time to acceptable values, several techniques have been investigated. The first type is to use analytical methods such as Rosenthal equations. The second type of solutions consists in performing a transient analysis using adaptive meshing. But, for a large proportion of the involved processes, practical experience demonstrates the existence of quasi steady state conditions over the major part of the heat source path. Numerical algorithms have therefore been developed to directly compute the steady temperature, metallurgical phase proportion and stress distributions. This paper gives a general overview of the different numerical methods used to simulate welding and surface treatment processes with a special emphasis on the steady state calculation. The benefits and limitations of each of them are discussed and applications are presented.展开更多
In this study,a numerical model for simulating two-phase flow is developed.The Cartesian grid with Adaptive Mesh Refinement(AMR)is adopted to reduce the computational cost.An explicit projection method is used for the...In this study,a numerical model for simulating two-phase flow is developed.The Cartesian grid with Adaptive Mesh Refinement(AMR)is adopted to reduce the computational cost.An explicit projection method is used for the time integration and the Finite Difference Method(FDM)is applied on a staggered grid for the discretization of spatial derivatives.The Volume of Fluid(VOF)method with Piecewise-Linear Interface Calculation(PLIC)is extended to the AMR grid to capture the gas-water interface accurately.A coarse-fine interface treatment method is developed to preserve the flux conservation at the interfaces.Several two-dimensional(2D)and three-dimensional(3D)benchmark cases are carried out for the validation of the model.2D and 3D shear flow tests are conducted to validate the extension of the VOF method to the AMR grid.A 2D linear sloshing case is considered in which the model is proved to have 2nd-order accuracy in space.The efficiency of applying the AMR grid is discussed with a nonlinear sloshing problem.Finally,2D solitary wave past stage and 2D/3D dam break are simulated to demonstrate that the model is able to simulate violent interface problems.展开更多
BACKGROUND Laparoscopic ventral mesh rectopexy(LVMR)continues to be a popular treatment option for rectal prolapse,obstructive defecation/faecal incontinence and rectoceles.In recent years there have been concerns reg...BACKGROUND Laparoscopic ventral mesh rectopexy(LVMR)continues to be a popular treatment option for rectal prolapse,obstructive defecation/faecal incontinence and rectoceles.In recent years there have been concerns regarding the safety of mesh placements in the pelvis.AIM To assess the safety of the mesh and the outcome of the procedure.METHODS Eighty-six patients underwent LVMR with Permacol(Biological)mesh from 2012 to 2018 at University Hospital Wishaw.Forty were treated for obstructive defecation secondary to prolapse,rectocele or internal rectal intussusception,38 for mixed symptoms obstructive defecation and incontinence,5 for pain and bleeding secondary to full thickness prolapse and 3 with symptoms of incontinence.Questionnaires for the calculation of Wexner scores for constipation and incontinence were completed by the patients who were followed up in the clinic 12 wk after surgery and again in 6-12 mo.The average review of their notes was 18.3±4.2 mo.RESULTS The median Wexner scores for constipation pre-operatively and post-operatively were 14.5[Interquartile range(IQR):10.5-18.5]and 3(IQR:1-6),respectively,while the median Wexner score for faecal incontinence was 11(IQR:7-15)and 2(IQR:0-5),respectively(P<0.01).There were 4(4.6%)recurrences,2 cases that presented with erosion of a suture through the rectum and one with diskitis.No mesh complications or mortalities were recorded.CONCLUSION LVMR using a Permacol mesh is a safe and effective procedure for the treatment of obstructive defecation/faecal incontinence,rectal prolapse,rectoceles and internal rectal prolapse/intussusception.展开更多
In this paper,a kind of Wire Mesh Casing Treatment(WMCT)is proposed to improve the stable operating range of the compressor.In contrast to the traditional circumferential groove,as for WMCT,a layer of wire mesh is lai...In this paper,a kind of Wire Mesh Casing Treatment(WMCT)is proposed to improve the stable operating range of the compressor.In contrast to the traditional circumferential groove,as for WMCT,a layer of wire mesh is laid on the surface of the circumferential groove.Parametric studies were conducted on the low-speed axial flow compressor,including the groove width,axial location,and mesh count.The optimum axial location for WMCT is related to its groove width.A higher wire mesh count results in a smaller compressor stall margin improvement.Steady simulations were carried out to study the effect of WMCT on the flow structure of the compressor.The wire mesh in the WMCT has a certain flow resistance,which restricts the flow into and out of the groove.Due to the WMCT,the flow parameter in the tip region of the rotor is less sensitive to changes in the operating conditions of the compressor.The WMCT causes the rotor tip blade loading to shift backward,inhibiting the formation of spill forward of the leakage flow,and thus improving the stability of the compressor.The flow resistance on the groove surface is a new degree-of-freedom for the casing treatment designer.展开更多
A kind of photoelectrode was innovated by anodising titanium mesh in H 2SO 4 solution and photo reduced in HAuCl 4 solution and named Ti/Au TiO 2 mesh electrode. The structural and surface morphology of the Ti/Au TiO ...A kind of photoelectrode was innovated by anodising titanium mesh in H 2SO 4 solution and photo reduced in HAuCl 4 solution and named Ti/Au TiO 2 mesh electrode. The structural and surface morphology of the Ti/Au TiO 2 mesh was examined by X ray diffraction, laser Raman spectra, scanning electronic microscopy(SEM) and X ray photoelectron spectroscopy respectively. The results indicate that its crystal structure, morphology and the size of pore are affected greatly by gold deposition. XPS measurement shows that the valence band of Ti/TiO 2 has two peaks: a wide one at 4.97 eV and a narrow one at 6.61 eV, which correspond mainly to π(nonbonding) and σ (bonding) O 2p orbitals. The emission intensity of O 2p orbitals becomes stronger and the width of the valence band increases with the increase of Au content. And the emission of nonbonding shifts toward lower binding energy and that of bonding O 2p orbitals shifts toward higher binding energy. The photoelectrocatalytic(PEC) oxidation of humic acid(HA) was investigated in terms of TOC. The PEC oxidation efficiency of Ti/Au TiO 2 mesh with optimal content of gold is higher than that of Ti/TiO 2 mesh. It is suggested that the recombination of electrons and holes is hindered owing to gold deposition. The investigation shows that PEC oxidation is a convenient way to mineralize organic matter for water treatment.展开更多
Background: Aloe vera has been used by many civilizations throughout history due to the numerous properties attributed. Gastro oesophageal reflux disease is a common disorder with consequences for the patient’s healt...Background: Aloe vera has been used by many civilizations throughout history due to the numerous properties attributed. Gastro oesophageal reflux disease is a common disorder with consequences for the patient’s health related quality of life. Aims: The purpose of this study was to assess the benefits of the Aloe vera in 80 patients with gastro oesophageal reflux. Methods: This is probably the first randomised and double-blind trail ever performed on this subject. The study included eight weeks of treatment with milk enriched with Aloe vera or placebo. Data of diet (frequency questionnaire), symptoms (gastrointestinal symptom rating scale) and quality of life (quality of life in reflux and disease) were obtained. Results: So far, there has been hardly any proof that Aloe vera decreases symptoms of reflux disease;on the contrary, a lower percentage of remission of pain is observed among the Aloe vera group. As long as its effectiveness has not been proven properly, the use of Aloe vera in reflux disease cannot be recommend. Conclusion: Aloe vera does not have a beneficial effect on reflux disease under the study conditions.展开更多
目的综合分析多种局部治疗方案对原发性肝癌合并门静脉癌栓(PVTT)患者的疗效,并尝试找到最佳的治疗方案。方法计算机检索PubMed、Web of Science、Embase、Cochrane Library、中国知网、万方数据库等,对符合纳入标准的文献进行文献质量...目的综合分析多种局部治疗方案对原发性肝癌合并门静脉癌栓(PVTT)患者的疗效,并尝试找到最佳的治疗方案。方法计算机检索PubMed、Web of Science、Embase、Cochrane Library、中国知网、万方数据库等,对符合纳入标准的文献进行文献质量评价,提取数据后使用Stata 17.1软件进行Meta分析。结果本研究共纳入33篇文献,共计3441例原发性肝癌合并PVTT患者,治疗方式涉及肝动脉化疗栓塞(TACE)、放疗、Sorafenib、碘125放疗(^(125)I)、TACE+放疗、TACE+^(125)I、TACE+门静脉化疗(PVC)、TACE+Sorafenib、TACE+射频消融(RFA)、TACE+Apatinib、肝动脉灌注化疗(HAIC)+Sorafenib、TACE+HAIC共10种干预措施。网状Meta分析结果显示:在预后评价指标中,TACE+放疗、TACE+Sorafenib、TACE+PVC对原发性肝癌合并PVTT患者的客观缓解率(ORR)效果较好;对于患者总生存时间(OS),TACE+RFA、TACE+Sorafenib和TACE+^(125)I方案效果较好;对于患者1年生存率,TACE+^(125)I、TACE+PVC和TACE+RFA方案效果较好。结论在原发性肝癌合并PVTT患者的局部治疗方案中,基于TACE治疗的联合治疗方案相较于单一的局部治疗在预后中有更明显的获益。展开更多
文摘Objective: To evaluate, in a comprehensive way, mesh and mesh free SUI treatment results obtained in a single center. The present study addresses the efficacy and safety of a novel surgical technique. Material & Methods: Adult female SUI patients, 184 in total, were divided within a sequential manner into two groups to be treated for SUI either with or without mesh insertion during a surgical intervention. In this novel procedure, a vertical vaginal incision from the urethra towards the bladder bottom is made and closed transversely. After the intervention the patients revisited the clinic at the 6th month. Results: 81 patients in mesh and 83 in the mesh free group completed the 2-year follow up. Based on the pad tests conducted at the end of 24-month follow up, 82% of the patients in the mesh free group and 85% in the mesh group were considered as successful if the pad test resulted with ≤2 gram. Cystocele of Grade I or II was also treated in 69 patients within the same single surgical procedure. Conclusion: The surgical outcomes of the mesh and mesh-free group were almost the same. However, though the cure rate of the mesh group was higher, it was not statistically significant. Adverse events were more frequent in the mesh group due to mesh presence.
文摘AIM: To evaluate the frequency of use of various treatment modalities for Budd-Chiari syndrome (BCS) in China by conducting a preliminary survey of relevant literature.
文摘A wide range of welding and surface treatment processes involve the use of a heat source which is moving at a constant speed over the component. The numerical simulation of such processes implies a transient analysis using a very refined mesh in order to follow properly the path of the heat source. The 3D-mesh size can be very large if one consider the welds length or the heat-treated surface size in industrial components. To reduce the computational time to acceptable values, several techniques have been investigated. The first type is to use analytical methods such as Rosenthal equations. The second type of solutions consists in performing a transient analysis using adaptive meshing. But, for a large proportion of the involved processes, practical experience demonstrates the existence of quasi steady state conditions over the major part of the heat source path. Numerical algorithms have therefore been developed to directly compute the steady temperature, metallurgical phase proportion and stress distributions. This paper gives a general overview of the different numerical methods used to simulate welding and surface treatment processes with a special emphasis on the steady state calculation. The benefits and limitations of each of them are discussed and applications are presented.
基金This work was financially supported by the National Natural Science Foundation of China(Nos.51779049,51879058,52071098,51979053).
文摘In this study,a numerical model for simulating two-phase flow is developed.The Cartesian grid with Adaptive Mesh Refinement(AMR)is adopted to reduce the computational cost.An explicit projection method is used for the time integration and the Finite Difference Method(FDM)is applied on a staggered grid for the discretization of spatial derivatives.The Volume of Fluid(VOF)method with Piecewise-Linear Interface Calculation(PLIC)is extended to the AMR grid to capture the gas-water interface accurately.A coarse-fine interface treatment method is developed to preserve the flux conservation at the interfaces.Several two-dimensional(2D)and three-dimensional(3D)benchmark cases are carried out for the validation of the model.2D and 3D shear flow tests are conducted to validate the extension of the VOF method to the AMR grid.A 2D linear sloshing case is considered in which the model is proved to have 2nd-order accuracy in space.The efficiency of applying the AMR grid is discussed with a nonlinear sloshing problem.Finally,2D solitary wave past stage and 2D/3D dam break are simulated to demonstrate that the model is able to simulate violent interface problems.
文摘BACKGROUND Laparoscopic ventral mesh rectopexy(LVMR)continues to be a popular treatment option for rectal prolapse,obstructive defecation/faecal incontinence and rectoceles.In recent years there have been concerns regarding the safety of mesh placements in the pelvis.AIM To assess the safety of the mesh and the outcome of the procedure.METHODS Eighty-six patients underwent LVMR with Permacol(Biological)mesh from 2012 to 2018 at University Hospital Wishaw.Forty were treated for obstructive defecation secondary to prolapse,rectocele or internal rectal intussusception,38 for mixed symptoms obstructive defecation and incontinence,5 for pain and bleeding secondary to full thickness prolapse and 3 with symptoms of incontinence.Questionnaires for the calculation of Wexner scores for constipation and incontinence were completed by the patients who were followed up in the clinic 12 wk after surgery and again in 6-12 mo.The average review of their notes was 18.3±4.2 mo.RESULTS The median Wexner scores for constipation pre-operatively and post-operatively were 14.5[Interquartile range(IQR):10.5-18.5]and 3(IQR:1-6),respectively,while the median Wexner score for faecal incontinence was 11(IQR:7-15)and 2(IQR:0-5),respectively(P<0.01).There were 4(4.6%)recurrences,2 cases that presented with erosion of a suture through the rectum and one with diskitis.No mesh complications or mortalities were recorded.CONCLUSION LVMR using a Permacol mesh is a safe and effective procedure for the treatment of obstructive defecation/faecal incontinence,rectal prolapse,rectoceles and internal rectal prolapse/intussusception.
基金supported by the National Natural Science Foundation of China(Nos.52325602 and U2241276)the Science Center for Gas Turbine Project,China(Nos.P2022-A-Ⅱ-002-001,P2022-C-Ⅱ-001-001 and P2022-CⅡ-003-001)+1 种基金the National Science and Technology Major Project,China(No.2017-Ⅱ-0005-0018)supported by the Key Laboratory of Pre-Research Management Centre,China(No.6142702200101)。
文摘In this paper,a kind of Wire Mesh Casing Treatment(WMCT)is proposed to improve the stable operating range of the compressor.In contrast to the traditional circumferential groove,as for WMCT,a layer of wire mesh is laid on the surface of the circumferential groove.Parametric studies were conducted on the low-speed axial flow compressor,including the groove width,axial location,and mesh count.The optimum axial location for WMCT is related to its groove width.A higher wire mesh count results in a smaller compressor stall margin improvement.Steady simulations were carried out to study the effect of WMCT on the flow structure of the compressor.The wire mesh in the WMCT has a certain flow resistance,which restricts the flow into and out of the groove.Due to the WMCT,the flow parameter in the tip region of the rotor is less sensitive to changes in the operating conditions of the compressor.The WMCT causes the rotor tip blade loading to shift backward,inhibiting the formation of spill forward of the leakage flow,and thus improving the stability of the compressor.The flow resistance on the groove surface is a new degree-of-freedom for the casing treatment designer.
文摘A kind of photoelectrode was innovated by anodising titanium mesh in H 2SO 4 solution and photo reduced in HAuCl 4 solution and named Ti/Au TiO 2 mesh electrode. The structural and surface morphology of the Ti/Au TiO 2 mesh was examined by X ray diffraction, laser Raman spectra, scanning electronic microscopy(SEM) and X ray photoelectron spectroscopy respectively. The results indicate that its crystal structure, morphology and the size of pore are affected greatly by gold deposition. XPS measurement shows that the valence band of Ti/TiO 2 has two peaks: a wide one at 4.97 eV and a narrow one at 6.61 eV, which correspond mainly to π(nonbonding) and σ (bonding) O 2p orbitals. The emission intensity of O 2p orbitals becomes stronger and the width of the valence band increases with the increase of Au content. And the emission of nonbonding shifts toward lower binding energy and that of bonding O 2p orbitals shifts toward higher binding energy. The photoelectrocatalytic(PEC) oxidation of humic acid(HA) was investigated in terms of TOC. The PEC oxidation efficiency of Ti/Au TiO 2 mesh with optimal content of gold is higher than that of Ti/TiO 2 mesh. It is suggested that the recombination of electrons and holes is hindered owing to gold deposition. The investigation shows that PEC oxidation is a convenient way to mineralize organic matter for water treatment.
文摘Background: Aloe vera has been used by many civilizations throughout history due to the numerous properties attributed. Gastro oesophageal reflux disease is a common disorder with consequences for the patient’s health related quality of life. Aims: The purpose of this study was to assess the benefits of the Aloe vera in 80 patients with gastro oesophageal reflux. Methods: This is probably the first randomised and double-blind trail ever performed on this subject. The study included eight weeks of treatment with milk enriched with Aloe vera or placebo. Data of diet (frequency questionnaire), symptoms (gastrointestinal symptom rating scale) and quality of life (quality of life in reflux and disease) were obtained. Results: So far, there has been hardly any proof that Aloe vera decreases symptoms of reflux disease;on the contrary, a lower percentage of remission of pain is observed among the Aloe vera group. As long as its effectiveness has not been proven properly, the use of Aloe vera in reflux disease cannot be recommend. Conclusion: Aloe vera does not have a beneficial effect on reflux disease under the study conditions.
文摘目的综合分析多种局部治疗方案对原发性肝癌合并门静脉癌栓(PVTT)患者的疗效,并尝试找到最佳的治疗方案。方法计算机检索PubMed、Web of Science、Embase、Cochrane Library、中国知网、万方数据库等,对符合纳入标准的文献进行文献质量评价,提取数据后使用Stata 17.1软件进行Meta分析。结果本研究共纳入33篇文献,共计3441例原发性肝癌合并PVTT患者,治疗方式涉及肝动脉化疗栓塞(TACE)、放疗、Sorafenib、碘125放疗(^(125)I)、TACE+放疗、TACE+^(125)I、TACE+门静脉化疗(PVC)、TACE+Sorafenib、TACE+射频消融(RFA)、TACE+Apatinib、肝动脉灌注化疗(HAIC)+Sorafenib、TACE+HAIC共10种干预措施。网状Meta分析结果显示:在预后评价指标中,TACE+放疗、TACE+Sorafenib、TACE+PVC对原发性肝癌合并PVTT患者的客观缓解率(ORR)效果较好;对于患者总生存时间(OS),TACE+RFA、TACE+Sorafenib和TACE+^(125)I方案效果较好;对于患者1年生存率,TACE+^(125)I、TACE+PVC和TACE+RFA方案效果较好。结论在原发性肝癌合并PVTT患者的局部治疗方案中,基于TACE治疗的联合治疗方案相较于单一的局部治疗在预后中有更明显的获益。
