Pattern recognition receptor(PRR)is a kind of sensor which is mainly expressed on the surface of innate immune cells.It can recognize pathogen related molecular patterns(PAMPs)or damage related molecular patterns(DAMP...Pattern recognition receptor(PRR)is a kind of sensor which is mainly expressed on the surface of innate immune cells.It can recognize pathogen related molecular patterns(PAMPs)or damage related molecular patterns(DAMPs).The innate immune system uses pattern recognition receptors to recognize pathogenic microorganisms in periodontal tissues and transmit signals to downstream pathways in time,thus triggering immune responses and then eliminating them.PRR has many family members,including toll like receptor family(TLRs),C-type lectin receptor family(CLRs),retinoic acid induced gene I(RIG-I)like receptor family(RLRs)and nucleotide binding oligomer domain(NOD)like receptor family(NLRs).Among them,RLRs are cytoplasmic receptors that recognize dsRNA from RNA viruses and have little association with chronic periodontitis.In this paper,the classification and structure of TLRs,CLRs,NLRs and the role of signal transduction pathway in chronic periodontitis are reviewed.In order to enrich the pathogenesis of periodontitis,provide new ideas for the treatment and prevention of chronic periodontitis.展开更多
Objective:To explore which pattern recognition receptors(PRRs)play a key role in the development of hand,foot,and mouth disease(HFMD)by analyzing PRR-associated genes.Methods:We conducted a comparative analysis of PRR...Objective:To explore which pattern recognition receptors(PRRs)play a key role in the development of hand,foot,and mouth disease(HFMD)by analyzing PRR-associated genes.Methods:We conducted a comparative analysis of PRR-associated gene expression in human peripheral blood mononuclear cells(PBMCs)infected with enterovirus 71(EV-A71)which were derived from patients with HFMD of different severities and at different stages.A total of 30 PRR-associated genes were identified as significantly upregulated both over time and across different EV-A71 isolates.Subsequently,ELISA was employed to quantify the expression of the six most prominent genes among these 30 identified genes,specifically,BST2,IRF7,IFI16,TRIM21,MX1,and DDX58.Results:Compared with those at the recovery stage,the expression levels of BST2(P=0.027),IFI16(P=0.016),MX1(P=0.046)and DDX58(P=0.008)in the acute stage of infection were significantly upregulated,while no significant difference in the expression levels of IRF7(P=0.495)and TRIM21(P=0.071)was found between different stages of the disease.The expression levels of BST2,IRF7,IFI16 and MX1 were significantly higher in children infected with single pathogen than those infected with mixed pathogens,and BST2,IRF7,IFI16 and MX1 expression levels were significantly lower in coxsackie B virus(COXB)positive patients than the negative patients.Expression levels of one or more of BST2,IRF7,IFI16,TRIM21,MX1 and DDX58 genes were correlated with PCT levels,various white blood cell counts,and serum antibody levels that reflect disease course of HFMD.Aspartate aminotransferase was correlated with BST2,MX1 and DDX58 expression levels.Conclusions:PRR-associated genes likely initiate the immune response in patients at the acute stage of HFMD.展开更多
Abrupt near-surface temperature changes in mountainous areas are a special component of the mountain climate system.Fast and accurate measurements of the locations,intensity,and width of the near-surface changes are n...Abrupt near-surface temperature changes in mountainous areas are a special component of the mountain climate system.Fast and accurate measurements of the locations,intensity,and width of the near-surface changes are necessary but highly difficult due to the complicated environmental conditions and instrumental issues.This paper develops a spatial pattern recognition method to measure the near-surface high temperature increase(NSHTI),one of the lesser-attended changes.First,raster window measurement was proposed to calculate the temperature lapse rate using MODIS land surface temperature and SRTM DEM data.It fully considers the terrain heights of two neighboring cells on opposite or adjacent slopes with a moving window of 3×3 cell size.Second,a threshold selection was performed to identify the NSHTI cells using a threshold of-0.65℃/100 m.Then,the NSHTI strips were parameterized through raster vectorization and spatial analysis.Taking Yunnan,a mountainous province in southwestern China,as the study area,the results indicate that the NSHTI cells concentrate in a strip-like pattern along the mountains and valleys,and the strips are almost parallel to the altitude contours with a slight northward uplift.Also,they are located mostly at a 3/5 height of high mountains or within 400 m from the valley floors,where the controlling topographic index is the altitude of the terrain trend surface but not the absolute elevation and the topographic uplift height and cutting depth.Additionally,the NSHTI intensity varies with the geographic locations and the proportions increase with an exponential trend,and the horizontal width has a mean of about 1000 m and a maximum of over 5000 m.The result demonstrates that the proposed method can effectively recognize NSHTI boundaries over mountains,providing support for the modeling of weather and climate systems and the development of mountain resources.展开更多
Objective:To study the value of serum pattern recognition receptors Collectin, Dectin and CD14 detection for disease evaluation in children with hand, foot and mouth disease (HFMD). Methods:76 children diagnosed with ...Objective:To study the value of serum pattern recognition receptors Collectin, Dectin and CD14 detection for disease evaluation in children with hand, foot and mouth disease (HFMD). Methods:76 children diagnosed with hand, foot and mouth disease in our hospital between May 2013 and March 2016 were selected as the HFMD group of the research, 80 healthy children receiving physical examination in our hospital during the same period were selected as the control group of the research, and the serum was collected to determine the levels of pattern recognition receptors, immunoglobulins, complements, inflammatory media and target organ damage indexes. Results:Serum Collectin, Dectin and CD14 levels of HFMD group were significantly higher than those of control group (P<0.05);serum immunoglobulin G (IgG) IgM, IgA, C3 and C4 levels of HFMD group were significantly lower than those of control group (P<0.05) and negatively correlated with Collectin, Dectin and CD14 levels;serum PCT, C-reactive protein (CRP), interleukin-6 (IL-6), IL-10, tumor necrosis factor-α(TNF-α), N-terminal pro-brain natriuretic peptide (NT-proBNP), neuron-specific enolase (NSE), S100βand surfactant protein A (SP-A) levels of HFMD group were significantly higher than those of control group (P<0.05) and positively correlated with Collectin, Dectin and CD14 levels. Conclusions:High expression of serum pattern recognition receptors Collectin, Dectin and CD14 in children with hand, foot and mouth disease is closely related to the immune response, inflammatory response and target organ function damage during the disease progression.展开更多
The pharmaceutical industry increasingly values medicinal plants due to their perceived safety and costeffectiveness compared to modern drugs.Throughout the extensive history of medicinal plant usage,various plant par...The pharmaceutical industry increasingly values medicinal plants due to their perceived safety and costeffectiveness compared to modern drugs.Throughout the extensive history of medicinal plant usage,various plant parts,including flowers,leaves,and roots,have been acknowledged for their healing properties and employed in plant identification.Leaf images,however,stand out as the preferred and easily accessible source of information.Manual plant identification by plant taxonomists is intricate,time-consuming,and prone to errors,relying heavily on human perception.Artificial intelligence(AI)techniques offer a solution by automating plant recognition processes.This study thoroughly examines cutting-edge AI approaches for leaf image-based plant identification,drawing insights from literature across renowned repositories.This paper critically summarizes relevant literature based on AI algorithms,extracted features,and results achieved.Additionally,it analyzes extensively used datasets in automated plant classification research.It also offers deep insights into implemented techniques and methods employed for medicinal plant recognition.Moreover,this rigorous review study discusses opportunities and challenges in employing these AI-based approaches.Furthermore,in-depth statistical findings and lessons learned from this survey are highlighted with novel research areas with the aim of offering insights to the readers and motivating new research directions.This review is expected to serve as a foundational resource for future researchers in the field of AI-based identification of medicinal plants.展开更多
Dynamic signature is a biometric modality that recognizes an individual’s anatomic and behavioural characteristics when signing their name. The rampant case of signature falsification (Identity Theft) was the key mot...Dynamic signature is a biometric modality that recognizes an individual’s anatomic and behavioural characteristics when signing their name. The rampant case of signature falsification (Identity Theft) was the key motivating factor for embarking on this study. This study was necessitated by the damages and dangers posed by signature forgery coupled with the intractable nature of the problem. The aim and objectives of this study is to design a proactive and responsive system that could compare two signature samples and detect the correct signature against the forged one. Dynamic Signature verification is an important biometric technique that aims to detect whether a given signature is genuine or forged. In this research work, Convolutional Neural Networks (CNNsor ConvNet) which is a class of deep, feed forward artificial neural networks that has successfully been applied to analysing visual imagery was used to train the model. The signature images are stored in a file directory structure which the Keras Python library can work with. Then the CNN was implemented in python using the Keras with the TensorFlow backend to learn the patterns associated with the signature. The result showed that for the same CNNs-based network experimental result of average accuracy, the larger the training dataset, the higher the test accuracy. However, when the training dataset are insufficient, better results can be obtained. The paper concluded that by training datasets using CNNs network, 98% accuracy in the result was recorded, in the experimental part, the model achieved a high degree of accuracy in the classification of the biometric parameters used.展开更多
Pattern recognition receptors(PRRs) play important roles in innate immunity system and trigger the specific pathogen recognition by detecting the pathogen-associated molecular patterns. The main four PRRs components i...Pattern recognition receptors(PRRs) play important roles in innate immunity system and trigger the specific pathogen recognition by detecting the pathogen-associated molecular patterns. The main four PRRs components including Toll-like receptors(TLRs), RIG-I-like receptors(RLRs), NOD-like receptors(NLRs) and C-type lectin receptors(CLRs) were surveyed in the five genomes of non-teleost ray-finned fishes(NTR) including bichir(Polypterus senegalus), American paddlefish(Polyodon spathula), alligator gar(Atractosteus spatula), spotted gar(Lepisosteus oculatus) and bowfin(Amia calva), representing all the four major basal groups of ray-finned fishes. The result indicates that all the four PRRs components have been well established in these NTR fishes. In the RLR-MAVS signal pathway, which detects intracellular RNA ligands to induce production of type I interferons(IFNs), the MAVS was lost in bichir particularly. Also, the essential genes of recognition of Lipopolysaccharide(LPS) commonly in mammals like MD2, LY96 and LBP could not be identified in NTR fishes. It is speculated that TLR4 in NTR fishes may act as a cooperator with other PRRs and has a different pathway of recognizing LPS compared with that in mammals. In addition, we provide a survey of NLR and CLR in NTR fishes. The CLRs results suggest that Group V receptors are absent in fishes and Group II and VI receptors are well established in the early vertebrate evolution. Our comprehensive research of PRRs involving NTR fishes provides a new insight into PRR evolution in primitive vertebrate.展开更多
From the perspective of geological zone selection for coalbed methane(CBM) development, the evaluation parameters(covering geological conditions and production conditions) of geological sweetspot for CBM development a...From the perspective of geological zone selection for coalbed methane(CBM) development, the evaluation parameters(covering geological conditions and production conditions) of geological sweetspot for CBM development are determined, and the evaluation index system of geological sweetspot for CBM development is established. On this basis, the fuzzy pattern recognition(FPR) model of geological sweetspot for CBM development is built. The model is applied to evaluate four units of No.3 Coal Seam in the Fanzhuang Block, southern Qinshui Basin, China. The evaluation results are consistent with the actual development effect and the existing research results, which verifies the rationality and reliability of the FPR model. The research shows that the proposed FPR model of geological sweetspot for CBM development does not involve parameter weighting which leads to uncertainties in the results of the conventional models such as analytic hierarchy process and multi-level fuzzy synthesis judgment, and features a simple computation without the construction of multi-level judgment matrix. The FPR model provides reliable results to support the efficient development of CBM.展开更多
The crack fault is one of the most common faults in the rotor system,and researchers have paid close attention to its fault diagnosis.However,most studies focus on discussing the dynamic response characteristics cause...The crack fault is one of the most common faults in the rotor system,and researchers have paid close attention to its fault diagnosis.However,most studies focus on discussing the dynamic response characteristics caused by the crack rather than estimating the crack depth and position based on the obtained vibration signals.In this paper,a novel crack fault diagnosis and location method for a dual-disk hollow shaft rotor system based on the Radial basis function(RBF)network and Pattern recognition neural network(PRNN)is presented.Firstly,a rotor system model with a breathing crack suitable for a short-thick hollow shaft rotor is established based on the finite element method,where the crack's periodic opening and closing pattern and different degrees of crack depth are considered.Then,the dynamic response is obtained by the harmonic balance method.By adjusting the crack parameters,the dynamic characteristics related to the crack depth and position are analyzed through the amplitude-frequency responses and waterfall plots.The analysis results show that the first critical speed,first subcritical speed,first critical speed amplitude,and super-harmonic resonance peak at the first subcritical speed can be utilized for the crack fault diagnosis.Based on this,the RBF network and PRNN are adopted to determine the depth and approximate location of the crack respectively by taking the above dynamic characteristics as input.Test results show that the proposed method has high fault diagnosis accuracy.This research proposes a crack detection method adequate for the hollow shaft rotor system,where the crack depth and position are both unknown.展开更多
This work focuses on radial basis functions containing no parameters with themain objective being to comparatively explore more of their effectiveness.For this,a total of sixteen forms of shapeless radial basis functi...This work focuses on radial basis functions containing no parameters with themain objective being to comparatively explore more of their effectiveness.For this,a total of sixteen forms of shapeless radial basis functions are gathered and investigated under the context of the pattern recognition problem through the structure of radial basis function neural networks,with the use of the Representational Capability(RC)algorithm.Different sizes of datasets are disturbed with noise before being imported into the algorithm as‘training/testing’datasets.Each shapeless radial basis function is monitored carefully with effectiveness criteria including accuracy,condition number(of the interpolation matrix),CPU time,CPU-storage requirement,underfitting and overfitting aspects,and the number of centres being generated.For the sake of comparison,the well-known Multiquadric-radial basis function is included as a representative of shape-contained radial basis functions.The numerical results have revealed that some forms of shapeless radial basis functions show good potential and are even better than Multiquadric itself indicating strongly that the future use of radial basis function may no longer face the pain of choosing a proper shape when shapeless forms may be equally(or even better)effective.展开更多
Landform elements with varying morphologies and spatial arrangements are recognized as feature indicator of landform classification and play a critical role in geomorphological studies.Differential geometry method has...Landform elements with varying morphologies and spatial arrangements are recognized as feature indicator of landform classification and play a critical role in geomorphological studies.Differential geometry method has been extensively applied in prior landform element research,while its efficacy in differentiating similar morphological characteristics remains inadequate to date.To reduce reliance on geomorphometric variables and increase awareness of landform patterns,geomorphons method was generated in previous study corresponding to specific landform reclassification map based on lookup table.Besides,to address the problem of feature similarity,hierarchical classification was proposed and effectively utilized for terrain recognition through the analytical strategy of fuzzy gradient features.Thus,combining the advantages of these two aspects,a hierarchical framework was proposed in this study for landform element pattern recognition considering the morphology and hierarchy factors.First,the local triplet patterns derived from geomorphons were enhanced by setting the flatness threshold,and subsequently adopted for the primary landform element recognition.Then,as geomorphic units with the same morphology possess different spatial analytical scales,the unidentified landform elements under the principle of scale adaptation were determined by calculating the spatial correlation and entropy information.To ensure the effectiveness of this proposed method,the sampling points were randomly selected from NASADEM data and then validated against a real 3D terrain model.Quantitative results of landform element pattern recognition demonstrate that our approach can reach above 77%average accuracy.Additionally,it delineates local details more effectively than geomorphons in visual assessment,resulting in a 7%accuracy improvement in overall scale.展开更多
Human personality assessment using gait pattern recognition is one of the most recent and exciting research domains.Gait is a person’s identity that can reflect reliable information about his mood,emotions,and substa...Human personality assessment using gait pattern recognition is one of the most recent and exciting research domains.Gait is a person’s identity that can reflect reliable information about his mood,emotions,and substantial personality traits under scrutiny.This research focuses on recognizing key personality traits,including neuroticism,extraversion,openness to experience,agreeableness,and conscientiousness,in line with the bigfive model of personality.We inferred personality traits based on the gait pattern recognition of individuals utilizing built-in smartphone sensors.For experimentation,we collected a novel dataset of 22 participants using an android application and further segmented it into six data chunks for a critical evaluation.After data pre-processing,we extracted selected features from each data segment and then applied four multiclass machine learning algorithms for training and classifying the dataset corresponding to the users’Big-Five Personality Traits Profiles(BFPT).Experimental results and performance evaluation of the classifiers revealed the efficacy of the proposed scheme for all big-five traits.展开更多
Based on the regularity nature of lower-limb motion,an intent pattern recognition approach for above-knee prosthesis is proposed in this paper. To remedy the defects of recognizer based on electromyogram(EMG), we deve...Based on the regularity nature of lower-limb motion,an intent pattern recognition approach for above-knee prosthesis is proposed in this paper. To remedy the defects of recognizer based on electromyogram(EMG), we develop a pure mechanical sensor architecture for intent pattern recognition of lower-limb motion. The sensor system is composed of an accelerometer, a gyroscope mounted on the prosthetic socket, and two pressure sensors mounted under the sole. To compensate the delay in the control of prosthesis, the signals in the stance phase are used to predict the terrain and speed in the swing phase. Specifically, the intent pattern recognizer utilizes intraclass correlation coefficient(ICC) according to the Cartesian product of walking speed and terrain. Moreover, the sensor data are fused via DempsterShafer's theory. And hidden Markov model(HMM) is used to recognize the realtime motion state with the reference of the prior step. The proposed method can infer the prosthesis user's intent of walking on different terrain, which includes level ground,stair ascent, stair descent, up and down ramp. The experiments demonstrate that the intent pattern recognizer is capable of identifying five typical terrain-modes with the rate of 95.8%. The outcome of this investigation is expected to substantially improve the control performance of powered above-knee prosthesis.展开更多
In order to improve the accuracy of travel demand forecast and considering the distribution of travel behaviors within time dimension, a trip chaining pattern recognition model was established based on activity purpos...In order to improve the accuracy of travel demand forecast and considering the distribution of travel behaviors within time dimension, a trip chaining pattern recognition model was established based on activity purposes by applying three methods: the support vector machine (SVM) model, the radial basis function neural network (RBFNN) model and the multinomial logit (MNL) model. The effect of explanatory factors on trip chaining behaviors and their contribution to model performace were investigated by sensitivity analysis. Results show that the SVM model has a better performance than the RBFNN model and the MNL model due to its higher overall and partial accuracy, indicating its recognition advantage under a smai sample size scenario. It is also proved that the SVM model is capable of estimating the effect of multi-category factors on trip chaining behaviors more accurately. The different contribution of explanatory, factors to trip chaining pattern recognition reflects the importance of refining trip chaining patterns ad exploring factors that are specific to each pattern. It is shown that the SVM technology in travel demand forecast modeling and analysis of explanatory variable effects is practical.展开更多
The concept of the degree of similarity between interval-valued intuitionistic fuzzy sets (IVIFSs) is introduced, and some distance measures between IVIFSs are defined based on the Hamming distance, the normalized H...The concept of the degree of similarity between interval-valued intuitionistic fuzzy sets (IVIFSs) is introduced, and some distance measures between IVIFSs are defined based on the Hamming distance, the normalized Hamming distance, the weighted Hamming distance, the Euclidean distance, the normalized Euclidean distance, and the weighted Euclidean distance, etc. Then, by combining the Hausdorff metric with the Hamming distance, the Euclidean distance and their weighted versions, two other similarity measures between IVIFSs, i. e., the weighted Hamming distance based on the Hausdorff metric and the weighted Euclidean distance based on the Hausdorff metric, are defined, and then some of their properties are studied. Finally, based on these distance measures, some similarity measures between IVIFSs are defined, and the similarity measures are applied to pattern recognitions with interval-valued intuitionistic fuzzy information.展开更多
This paper develops a fuzzy pattern recognition model for group decision making to solve the problem of lectotype optimization of offshore platforms. The lack of data and the inexact or incomplete information for crit...This paper develops a fuzzy pattern recognition model for group decision making to solve the problem of lectotype optimization of offshore platforms. The lack of data and the inexact or incomplete information for criteria are the main cause of uncertainty in the evaluation process, therefore it is necessary to integrate the judgments from different decision makers with different experience, knowledge and preference. This paper first uses a complementary principle based pairwise comparison method to obtain the subjective weight of the criteria from each decision maker. A fuzzy pattern recognition model is then developed to integrate the judgments from all the decision makers and the information from the criteria, under the supervision of the subjective weights. Finally a case study is given to show the efficiency and robustness of the proposed model.展开更多
We present a new pattern recognition system based on moving average and linear discriminant analysis (LDA), which can be used to process the original signal of the new polymer quartz piezoelectric crystal air-sensit...We present a new pattern recognition system based on moving average and linear discriminant analysis (LDA), which can be used to process the original signal of the new polymer quartz piezoelectric crystal air-sensitive sensor system we designed, called the new e-nose. Using the new e-nose, we obtain the template datum of Chinese spirits via a new pattern recognition system. To verify the effectiveness of the new pattern recognition system, we select three kinds of Chinese spirits to test, our results confirm that the new pattern recognition system can perfectly identify and distinguish between the Chinese spirits.展开更多
This paper presents a new pattern recognition system for Chinese spirit identification by using the polymer quartz piezoelectric crystal sensor based e-nose. The sensors are designed based on quartz crystal microbala...This paper presents a new pattern recognition system for Chinese spirit identification by using the polymer quartz piezoelectric crystal sensor based e-nose. The sensors are designed based on quartz crystal microbalance(QCM) principle,and they could capture different vibration frequency signal values for Chinese spirit identification. For each sensor in an8-channel sensor array, seven characteristic values of the original vibration frequency signal values, i.e., average value(A),root-mean-square value(RMS), shape factor value(S_f), crest factor value(C_f), impulse factor value(I_f), clearance factor value(CL_f), kurtosis factor value(K_v) are first extracted. Then the dimension of the characteristic values is reduced by the principle components analysis(PCA) method. Finally the back propagation(BP) neutral network algorithm is used to recognize Chinese spirits. The experimental results show that the recognition rate of six kinds of Chinese spirits is 93.33% and our proposed new pattern recognition system can identify Chinese spirits effectively.展开更多
Water quality assessment of lakes is important to determine functional zones of water use.Considering the fuzziness during the partitioning process for lake water quality in an arid area,a multiplex model of fuzzy clu...Water quality assessment of lakes is important to determine functional zones of water use.Considering the fuzziness during the partitioning process for lake water quality in an arid area,a multiplex model of fuzzy clustering with pattern recognition was developed by integrating transitive closure method,ISODATA algorithm in fuzzy clustering and fuzzy pattern recognition.The model was applied to partition the Ulansuhai Lake,a typical shallow lake in arid climate zone in the west part of Inner Mongolia,China and grade the condition of water quality divisions.The results showed that the partition well matched the real conditions of the lake,and the method has been proved accurate in the application.展开更多
Fingerprint image is a typical non-restraint image that has some uncertainty, which makes it difficult to perform identification using classical approach. Therefore, fuzzy pattern recognition is applied to match indiv...Fingerprint image is a typical non-restraint image that has some uncertainty, which makes it difficult to perform identification using classical approach. Therefore, fuzzy pattern recognition is applied to match individual query by searching the entire template database. The fuzzy maximum subordinate principle is used to solve shift matching. Through experimenting and analyzing, the approximate principle fuzzy method is employed by selecting fuzzy characteristics and determining the similarity function to achieve the further accuracy. Theoretical and experimental results show this approach is effective and reasonable.展开更多
基金Scientific research project of Hainan Provincial Department of Education(No.hnky2018zd-7)。
文摘Pattern recognition receptor(PRR)is a kind of sensor which is mainly expressed on the surface of innate immune cells.It can recognize pathogen related molecular patterns(PAMPs)or damage related molecular patterns(DAMPs).The innate immune system uses pattern recognition receptors to recognize pathogenic microorganisms in periodontal tissues and transmit signals to downstream pathways in time,thus triggering immune responses and then eliminating them.PRR has many family members,including toll like receptor family(TLRs),C-type lectin receptor family(CLRs),retinoic acid induced gene I(RIG-I)like receptor family(RLRs)and nucleotide binding oligomer domain(NOD)like receptor family(NLRs).Among them,RLRs are cytoplasmic receptors that recognize dsRNA from RNA viruses and have little association with chronic periodontitis.In this paper,the classification and structure of TLRs,CLRs,NLRs and the role of signal transduction pathway in chronic periodontitis are reviewed.In order to enrich the pathogenesis of periodontitis,provide new ideas for the treatment and prevention of chronic periodontitis.
文摘Objective:To explore which pattern recognition receptors(PRRs)play a key role in the development of hand,foot,and mouth disease(HFMD)by analyzing PRR-associated genes.Methods:We conducted a comparative analysis of PRR-associated gene expression in human peripheral blood mononuclear cells(PBMCs)infected with enterovirus 71(EV-A71)which were derived from patients with HFMD of different severities and at different stages.A total of 30 PRR-associated genes were identified as significantly upregulated both over time and across different EV-A71 isolates.Subsequently,ELISA was employed to quantify the expression of the six most prominent genes among these 30 identified genes,specifically,BST2,IRF7,IFI16,TRIM21,MX1,and DDX58.Results:Compared with those at the recovery stage,the expression levels of BST2(P=0.027),IFI16(P=0.016),MX1(P=0.046)and DDX58(P=0.008)in the acute stage of infection were significantly upregulated,while no significant difference in the expression levels of IRF7(P=0.495)and TRIM21(P=0.071)was found between different stages of the disease.The expression levels of BST2,IRF7,IFI16 and MX1 were significantly higher in children infected with single pathogen than those infected with mixed pathogens,and BST2,IRF7,IFI16 and MX1 expression levels were significantly lower in coxsackie B virus(COXB)positive patients than the negative patients.Expression levels of one or more of BST2,IRF7,IFI16,TRIM21,MX1 and DDX58 genes were correlated with PCT levels,various white blood cell counts,and serum antibody levels that reflect disease course of HFMD.Aspartate aminotransferase was correlated with BST2,MX1 and DDX58 expression levels.Conclusions:PRR-associated genes likely initiate the immune response in patients at the acute stage of HFMD.
基金supported by the National Natural Science Foundation of China (Grant No. 42061004)the Joint Special Project of Agricultural Basic Research of Yunnan Province (Grant No. 202101BD070001093)the Youth Special Project of Xingdian Talent Support Program of Yunnan Province
文摘Abrupt near-surface temperature changes in mountainous areas are a special component of the mountain climate system.Fast and accurate measurements of the locations,intensity,and width of the near-surface changes are necessary but highly difficult due to the complicated environmental conditions and instrumental issues.This paper develops a spatial pattern recognition method to measure the near-surface high temperature increase(NSHTI),one of the lesser-attended changes.First,raster window measurement was proposed to calculate the temperature lapse rate using MODIS land surface temperature and SRTM DEM data.It fully considers the terrain heights of two neighboring cells on opposite or adjacent slopes with a moving window of 3×3 cell size.Second,a threshold selection was performed to identify the NSHTI cells using a threshold of-0.65℃/100 m.Then,the NSHTI strips were parameterized through raster vectorization and spatial analysis.Taking Yunnan,a mountainous province in southwestern China,as the study area,the results indicate that the NSHTI cells concentrate in a strip-like pattern along the mountains and valleys,and the strips are almost parallel to the altitude contours with a slight northward uplift.Also,they are located mostly at a 3/5 height of high mountains or within 400 m from the valley floors,where the controlling topographic index is the altitude of the terrain trend surface but not the absolute elevation and the topographic uplift height and cutting depth.Additionally,the NSHTI intensity varies with the geographic locations and the proportions increase with an exponential trend,and the horizontal width has a mean of about 1000 m and a maximum of over 5000 m.The result demonstrates that the proposed method can effectively recognize NSHTI boundaries over mountains,providing support for the modeling of weather and climate systems and the development of mountain resources.
文摘Objective:To study the value of serum pattern recognition receptors Collectin, Dectin and CD14 detection for disease evaluation in children with hand, foot and mouth disease (HFMD). Methods:76 children diagnosed with hand, foot and mouth disease in our hospital between May 2013 and March 2016 were selected as the HFMD group of the research, 80 healthy children receiving physical examination in our hospital during the same period were selected as the control group of the research, and the serum was collected to determine the levels of pattern recognition receptors, immunoglobulins, complements, inflammatory media and target organ damage indexes. Results:Serum Collectin, Dectin and CD14 levels of HFMD group were significantly higher than those of control group (P<0.05);serum immunoglobulin G (IgG) IgM, IgA, C3 and C4 levels of HFMD group were significantly lower than those of control group (P<0.05) and negatively correlated with Collectin, Dectin and CD14 levels;serum PCT, C-reactive protein (CRP), interleukin-6 (IL-6), IL-10, tumor necrosis factor-α(TNF-α), N-terminal pro-brain natriuretic peptide (NT-proBNP), neuron-specific enolase (NSE), S100βand surfactant protein A (SP-A) levels of HFMD group were significantly higher than those of control group (P<0.05) and positively correlated with Collectin, Dectin and CD14 levels. Conclusions:High expression of serum pattern recognition receptors Collectin, Dectin and CD14 in children with hand, foot and mouth disease is closely related to the immune response, inflammatory response and target organ function damage during the disease progression.
文摘The pharmaceutical industry increasingly values medicinal plants due to their perceived safety and costeffectiveness compared to modern drugs.Throughout the extensive history of medicinal plant usage,various plant parts,including flowers,leaves,and roots,have been acknowledged for their healing properties and employed in plant identification.Leaf images,however,stand out as the preferred and easily accessible source of information.Manual plant identification by plant taxonomists is intricate,time-consuming,and prone to errors,relying heavily on human perception.Artificial intelligence(AI)techniques offer a solution by automating plant recognition processes.This study thoroughly examines cutting-edge AI approaches for leaf image-based plant identification,drawing insights from literature across renowned repositories.This paper critically summarizes relevant literature based on AI algorithms,extracted features,and results achieved.Additionally,it analyzes extensively used datasets in automated plant classification research.It also offers deep insights into implemented techniques and methods employed for medicinal plant recognition.Moreover,this rigorous review study discusses opportunities and challenges in employing these AI-based approaches.Furthermore,in-depth statistical findings and lessons learned from this survey are highlighted with novel research areas with the aim of offering insights to the readers and motivating new research directions.This review is expected to serve as a foundational resource for future researchers in the field of AI-based identification of medicinal plants.
文摘Dynamic signature is a biometric modality that recognizes an individual’s anatomic and behavioural characteristics when signing their name. The rampant case of signature falsification (Identity Theft) was the key motivating factor for embarking on this study. This study was necessitated by the damages and dangers posed by signature forgery coupled with the intractable nature of the problem. The aim and objectives of this study is to design a proactive and responsive system that could compare two signature samples and detect the correct signature against the forged one. Dynamic Signature verification is an important biometric technique that aims to detect whether a given signature is genuine or forged. In this research work, Convolutional Neural Networks (CNNsor ConvNet) which is a class of deep, feed forward artificial neural networks that has successfully been applied to analysing visual imagery was used to train the model. The signature images are stored in a file directory structure which the Keras Python library can work with. Then the CNN was implemented in python using the Keras with the TensorFlow backend to learn the patterns associated with the signature. The result showed that for the same CNNs-based network experimental result of average accuracy, the larger the training dataset, the higher the test accuracy. However, when the training dataset are insufficient, better results can be obtained. The paper concluded that by training datasets using CNNs network, 98% accuracy in the result was recorded, in the experimental part, the model achieved a high degree of accuracy in the classification of the biometric parameters used.
基金supported by the National Natural Science Foundation of China(31372190)
文摘Pattern recognition receptors(PRRs) play important roles in innate immunity system and trigger the specific pathogen recognition by detecting the pathogen-associated molecular patterns. The main four PRRs components including Toll-like receptors(TLRs), RIG-I-like receptors(RLRs), NOD-like receptors(NLRs) and C-type lectin receptors(CLRs) were surveyed in the five genomes of non-teleost ray-finned fishes(NTR) including bichir(Polypterus senegalus), American paddlefish(Polyodon spathula), alligator gar(Atractosteus spatula), spotted gar(Lepisosteus oculatus) and bowfin(Amia calva), representing all the four major basal groups of ray-finned fishes. The result indicates that all the four PRRs components have been well established in these NTR fishes. In the RLR-MAVS signal pathway, which detects intracellular RNA ligands to induce production of type I interferons(IFNs), the MAVS was lost in bichir particularly. Also, the essential genes of recognition of Lipopolysaccharide(LPS) commonly in mammals like MD2, LY96 and LBP could not be identified in NTR fishes. It is speculated that TLR4 in NTR fishes may act as a cooperator with other PRRs and has a different pathway of recognizing LPS compared with that in mammals. In addition, we provide a survey of NLR and CLR in NTR fishes. The CLRs results suggest that Group V receptors are absent in fishes and Group II and VI receptors are well established in the early vertebrate evolution. Our comprehensive research of PRRs involving NTR fishes provides a new insight into PRR evolution in primitive vertebrate.
基金Key Project of China National Natural Science Foundation (42230814,52234002)Research Program Foundation of Key Laboratory of Tectonics and Petroleum Resources (China University of Geosciences),Ministry of Education (TPR-2022-17)。
文摘From the perspective of geological zone selection for coalbed methane(CBM) development, the evaluation parameters(covering geological conditions and production conditions) of geological sweetspot for CBM development are determined, and the evaluation index system of geological sweetspot for CBM development is established. On this basis, the fuzzy pattern recognition(FPR) model of geological sweetspot for CBM development is built. The model is applied to evaluate four units of No.3 Coal Seam in the Fanzhuang Block, southern Qinshui Basin, China. The evaluation results are consistent with the actual development effect and the existing research results, which verifies the rationality and reliability of the FPR model. The research shows that the proposed FPR model of geological sweetspot for CBM development does not involve parameter weighting which leads to uncertainties in the results of the conventional models such as analytic hierarchy process and multi-level fuzzy synthesis judgment, and features a simple computation without the construction of multi-level judgment matrix. The FPR model provides reliable results to support the efficient development of CBM.
基金Supported by National Natural Science Foundation of China (Grant No.11972129)National Science and Technology Major Project of China (Grant No.2017-IV-0008-0045)+1 种基金Heilongjiang Provincial Natural Science Foundation (Grant No.YQ2022A008)the Fundamental Research Funds for the Central Universities。
文摘The crack fault is one of the most common faults in the rotor system,and researchers have paid close attention to its fault diagnosis.However,most studies focus on discussing the dynamic response characteristics caused by the crack rather than estimating the crack depth and position based on the obtained vibration signals.In this paper,a novel crack fault diagnosis and location method for a dual-disk hollow shaft rotor system based on the Radial basis function(RBF)network and Pattern recognition neural network(PRNN)is presented.Firstly,a rotor system model with a breathing crack suitable for a short-thick hollow shaft rotor is established based on the finite element method,where the crack's periodic opening and closing pattern and different degrees of crack depth are considered.Then,the dynamic response is obtained by the harmonic balance method.By adjusting the crack parameters,the dynamic characteristics related to the crack depth and position are analyzed through the amplitude-frequency responses and waterfall plots.The analysis results show that the first critical speed,first subcritical speed,first critical speed amplitude,and super-harmonic resonance peak at the first subcritical speed can be utilized for the crack fault diagnosis.Based on this,the RBF network and PRNN are adopted to determine the depth and approximate location of the crack respectively by taking the above dynamic characteristics as input.Test results show that the proposed method has high fault diagnosis accuracy.This research proposes a crack detection method adequate for the hollow shaft rotor system,where the crack depth and position are both unknown.
文摘This work focuses on radial basis functions containing no parameters with themain objective being to comparatively explore more of their effectiveness.For this,a total of sixteen forms of shapeless radial basis functions are gathered and investigated under the context of the pattern recognition problem through the structure of radial basis function neural networks,with the use of the Representational Capability(RC)algorithm.Different sizes of datasets are disturbed with noise before being imported into the algorithm as‘training/testing’datasets.Each shapeless radial basis function is monitored carefully with effectiveness criteria including accuracy,condition number(of the interpolation matrix),CPU time,CPU-storage requirement,underfitting and overfitting aspects,and the number of centres being generated.For the sake of comparison,the well-known Multiquadric-radial basis function is included as a representative of shape-contained radial basis functions.The numerical results have revealed that some forms of shapeless radial basis functions show good potential and are even better than Multiquadric itself indicating strongly that the future use of radial basis function may no longer face the pain of choosing a proper shape when shapeless forms may be equally(or even better)effective.
基金supported by the National Natural Science Foundation of China(Grant Nos.41930102,41971339 and 41771423)Shandong University of Science and Technology Research Fund(No.2019TDJH103)。
文摘Landform elements with varying morphologies and spatial arrangements are recognized as feature indicator of landform classification and play a critical role in geomorphological studies.Differential geometry method has been extensively applied in prior landform element research,while its efficacy in differentiating similar morphological characteristics remains inadequate to date.To reduce reliance on geomorphometric variables and increase awareness of landform patterns,geomorphons method was generated in previous study corresponding to specific landform reclassification map based on lookup table.Besides,to address the problem of feature similarity,hierarchical classification was proposed and effectively utilized for terrain recognition through the analytical strategy of fuzzy gradient features.Thus,combining the advantages of these two aspects,a hierarchical framework was proposed in this study for landform element pattern recognition considering the morphology and hierarchy factors.First,the local triplet patterns derived from geomorphons were enhanced by setting the flatness threshold,and subsequently adopted for the primary landform element recognition.Then,as geomorphic units with the same morphology possess different spatial analytical scales,the unidentified landform elements under the principle of scale adaptation were determined by calculating the spatial correlation and entropy information.To ensure the effectiveness of this proposed method,the sampling points were randomly selected from NASADEM data and then validated against a real 3D terrain model.Quantitative results of landform element pattern recognition demonstrate that our approach can reach above 77%average accuracy.Additionally,it delineates local details more effectively than geomorphons in visual assessment,resulting in a 7%accuracy improvement in overall scale.
基金This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(grant number:HI21C1831)the Soonchunhyang University Research Fund.
文摘Human personality assessment using gait pattern recognition is one of the most recent and exciting research domains.Gait is a person’s identity that can reflect reliable information about his mood,emotions,and substantial personality traits under scrutiny.This research focuses on recognizing key personality traits,including neuroticism,extraversion,openness to experience,agreeableness,and conscientiousness,in line with the bigfive model of personality.We inferred personality traits based on the gait pattern recognition of individuals utilizing built-in smartphone sensors.For experimentation,we collected a novel dataset of 22 participants using an android application and further segmented it into six data chunks for a critical evaluation.After data pre-processing,we extracted selected features from each data segment and then applied four multiclass machine learning algorithms for training and classifying the dataset corresponding to the users’Big-Five Personality Traits Profiles(BFPT).Experimental results and performance evaluation of the classifiers revealed the efficacy of the proposed scheme for all big-five traits.
基金supported in part by the National Nature Science Fundation(61174009,61203323)Youth Foundation of Hebei Province(F2016202327)+3 种基金the Colleges and Universities in Hebei Province Science and Technology Research Project(ZC2016020)supported in part by Key Project of NSFC(61533009)111 Project(B08015)Research Project(JCYJ20150403161923519)
文摘Based on the regularity nature of lower-limb motion,an intent pattern recognition approach for above-knee prosthesis is proposed in this paper. To remedy the defects of recognizer based on electromyogram(EMG), we develop a pure mechanical sensor architecture for intent pattern recognition of lower-limb motion. The sensor system is composed of an accelerometer, a gyroscope mounted on the prosthetic socket, and two pressure sensors mounted under the sole. To compensate the delay in the control of prosthesis, the signals in the stance phase are used to predict the terrain and speed in the swing phase. Specifically, the intent pattern recognizer utilizes intraclass correlation coefficient(ICC) according to the Cartesian product of walking speed and terrain. Moreover, the sensor data are fused via DempsterShafer's theory. And hidden Markov model(HMM) is used to recognize the realtime motion state with the reference of the prior step. The proposed method can infer the prosthesis user's intent of walking on different terrain, which includes level ground,stair ascent, stair descent, up and down ramp. The experiments demonstrate that the intent pattern recognizer is capable of identifying five typical terrain-modes with the rate of 95.8%. The outcome of this investigation is expected to substantially improve the control performance of powered above-knee prosthesis.
基金The Fundamental Research Funds for the Central Universities,the Scientific Innovation Research of College Graduates in Jiangsu Province(No.KYLX_0177)
文摘In order to improve the accuracy of travel demand forecast and considering the distribution of travel behaviors within time dimension, a trip chaining pattern recognition model was established based on activity purposes by applying three methods: the support vector machine (SVM) model, the radial basis function neural network (RBFNN) model and the multinomial logit (MNL) model. The effect of explanatory factors on trip chaining behaviors and their contribution to model performace were investigated by sensitivity analysis. Results show that the SVM model has a better performance than the RBFNN model and the MNL model due to its higher overall and partial accuracy, indicating its recognition advantage under a smai sample size scenario. It is also proved that the SVM model is capable of estimating the effect of multi-category factors on trip chaining behaviors more accurately. The different contribution of explanatory, factors to trip chaining pattern recognition reflects the importance of refining trip chaining patterns ad exploring factors that are specific to each pattern. It is shown that the SVM technology in travel demand forecast modeling and analysis of explanatory variable effects is practical.
基金The National Natural Science Foundation of China (No70571087)the National Science Fund for Distinguished Young Scholarsof China (No70625005)
文摘The concept of the degree of similarity between interval-valued intuitionistic fuzzy sets (IVIFSs) is introduced, and some distance measures between IVIFSs are defined based on the Hamming distance, the normalized Hamming distance, the weighted Hamming distance, the Euclidean distance, the normalized Euclidean distance, and the weighted Euclidean distance, etc. Then, by combining the Hausdorff metric with the Hamming distance, the Euclidean distance and their weighted versions, two other similarity measures between IVIFSs, i. e., the weighted Hamming distance based on the Hausdorff metric and the weighted Euclidean distance based on the Hausdorff metric, are defined, and then some of their properties are studied. Finally, based on these distance measures, some similarity measures between IVIFSs are defined, and the similarity measures are applied to pattern recognitions with interval-valued intuitionistic fuzzy information.
文摘This paper develops a fuzzy pattern recognition model for group decision making to solve the problem of lectotype optimization of offshore platforms. The lack of data and the inexact or incomplete information for criteria are the main cause of uncertainty in the evaluation process, therefore it is necessary to integrate the judgments from different decision makers with different experience, knowledge and preference. This paper first uses a complementary principle based pairwise comparison method to obtain the subjective weight of the criteria from each decision maker. A fuzzy pattern recognition model is then developed to integrate the judgments from all the decision makers and the information from the criteria, under the supervision of the subjective weights. Finally a case study is given to show the efficiency and robustness of the proposed model.
基金Project supported by the National High Technology Research and Development Program of China(Grant No.2013AA030901)
文摘We present a new pattern recognition system based on moving average and linear discriminant analysis (LDA), which can be used to process the original signal of the new polymer quartz piezoelectric crystal air-sensitive sensor system we designed, called the new e-nose. Using the new e-nose, we obtain the template datum of Chinese spirits via a new pattern recognition system. To verify the effectiveness of the new pattern recognition system, we select three kinds of Chinese spirits to test, our results confirm that the new pattern recognition system can perfectly identify and distinguish between the Chinese spirits.
基金Project supported by the National High Technology Research and Development Program of China(Grant No.2013AA030901)the Fundamental Research Funds for the Central Universities,China(Grant No.FRF-TP-14-120A2)
文摘This paper presents a new pattern recognition system for Chinese spirit identification by using the polymer quartz piezoelectric crystal sensor based e-nose. The sensors are designed based on quartz crystal microbalance(QCM) principle,and they could capture different vibration frequency signal values for Chinese spirit identification. For each sensor in an8-channel sensor array, seven characteristic values of the original vibration frequency signal values, i.e., average value(A),root-mean-square value(RMS), shape factor value(S_f), crest factor value(C_f), impulse factor value(I_f), clearance factor value(CL_f), kurtosis factor value(K_v) are first extracted. Then the dimension of the characteristic values is reduced by the principle components analysis(PCA) method. Finally the back propagation(BP) neutral network algorithm is used to recognize Chinese spirits. The experimental results show that the recognition rate of six kinds of Chinese spirits is 93.33% and our proposed new pattern recognition system can identify Chinese spirits effectively.
基金Supported by the National Natural Science Foundation of China (No.50269001, 50569002, 50669004)Natural Science Foundation of Inner Mongolia (No.200208020512, 200711020604)The Key Scientific and Technologic Project of the 10th Five-Year Plan of Inner Mongolia (No.20010103)
文摘Water quality assessment of lakes is important to determine functional zones of water use.Considering the fuzziness during the partitioning process for lake water quality in an arid area,a multiplex model of fuzzy clustering with pattern recognition was developed by integrating transitive closure method,ISODATA algorithm in fuzzy clustering and fuzzy pattern recognition.The model was applied to partition the Ulansuhai Lake,a typical shallow lake in arid climate zone in the west part of Inner Mongolia,China and grade the condition of water quality divisions.The results showed that the partition well matched the real conditions of the lake,and the method has been proved accurate in the application.
文摘Fingerprint image is a typical non-restraint image that has some uncertainty, which makes it difficult to perform identification using classical approach. Therefore, fuzzy pattern recognition is applied to match individual query by searching the entire template database. The fuzzy maximum subordinate principle is used to solve shift matching. Through experimenting and analyzing, the approximate principle fuzzy method is employed by selecting fuzzy characteristics and determining the similarity function to achieve the further accuracy. Theoretical and experimental results show this approach is effective and reasonable.