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Experimental study on energy characteristics and ignition performance of recessed multichannel plasma igniter 被引量:3
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作者 Bang-Huang Cai Hui-Min Song +3 位作者 Min Jia Yun Wu Wei Cui Sheng-Fang Huang 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第6期339-348,共10页
In the extreme conditions of high altitude,low temperature,low pressure,and high speed,the aircraft engine is prone to flameout and difficult to start secondary ignition,which makes reliable ignition of combustion cha... In the extreme conditions of high altitude,low temperature,low pressure,and high speed,the aircraft engine is prone to flameout and difficult to start secondary ignition,which makes reliable ignition of combustion chamber at high altitude become a worldwide problem.To solve this problem,a kind of multichannel plasma igniter with round cavity is proposed in this paper,the three-channel and five-channel igniters are compared with the traditional ones.The discharge energy of the three igniters was compared based on the electric energy test and the thermal energy test,and ignition experiments was conducted in the simulated high-altitude environment of the component combustion chamber.The results show that the recessed multichannel plasma igniter has higher discharge energy than the conventional spark igniter,which can increase the conversion efficiency of electric energy from 26%to 43%,and the conversion efficiency of thermal energy from 25%to 73%.The recessed multichannel plasma igniter can achieve greater spark penetration depth and excitation area,which both increase with the increase of height.At the same height,the inlet flow helps to increase the penetration depth of the spark.The recessed multichannel plasma igniter can widen the lean ignition boundary,and the maximum enrichment percentage of lean ignition boundary can reach 31%. 展开更多
关键词 high altitude extreme condition recessed multichannel plasma igniter discharge energy lean ignition boundary
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Characteristics and threshold voltage model of GaN-based FinFET with recessed gate
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作者 Chong Wang Xin Wang Slab +9 位作者 Xue-Feng Zheng Yun Wang Yun-Long He Ye Tianl Qing He Ji Wul Wei Mao Xiao-Hua Ma Jin-Cheng Zhang Yue Hao 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第9期535-539,共5页
In this work, AlGaN/GaN FinFETs with different fin widths have been successfully fabricated, and the recessed-gate FinFETs are fabricated for comparison. The recessed-gate FinFETs exhibit higher transconductance value... In this work, AlGaN/GaN FinFETs with different fin widths have been successfully fabricated, and the recessed-gate FinFETs are fabricated for comparison. The recessed-gate FinFETs exhibit higher transconductance value and positive shift of threshold voltage. Moreover, with the fin width of the recessed-gate FinFETs increasing, the variations of both threshold voltage and the transconductance increase. Next, transfer characteristics of the recessed-gate FinFETs with different fin widths and recessed-gate depths are simulated by Silvaco software. The relationship between the threshold voltage and the AlGaN layer thickness has been investigated. The simulation results indicate that the slope of threshold voltage variation reduces with the fin width decreasing. Finally, a simplified threshold voltage model for recessed-gate FinFET is established,which agrees with both the experimental results and simulation results. 展开更多
关键词 ALGAN/GAN FINFET recessed gate threshold voltage
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Influence of dry-etching damage on the electrical properties of an AlGaN/GaN Schottky barrier diode with recessed anode
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作者 钟健 姚尧 +9 位作者 郑越 杨帆 倪毅强 贺致远 沈震 周桂林 周德秋 吴志盛 张伯君 刘扬 《Chinese Physics B》 SCIE EI CAS CSCD 2015年第9期479-483,共5页
The influences of dry-etching damage on the electrical properties of an AlGaN/GaN Schottky barrier diode with ICPrecessed anode was investigated for the first time. It was found that the turn-on voltage is decreased w... The influences of dry-etching damage on the electrical properties of an AlGaN/GaN Schottky barrier diode with ICPrecessed anode was investigated for the first time. It was found that the turn-on voltage is decreased with the increase of dry-etching power. Furthermore, the leakage currents in the reverse bias region above pinch-off voltage rise as radio frequency(RF) power increases, while below pinch-off voltage, leakage currents tend to be independent of RF power.Based on detailed current–voltage–temperature(I–V –T) measurements, the barrier height of thermionic-field emission(TFE) from GaN is lowered as RF power increases, which results in early conduction. The increase of leakage current can be explained by Frenkel–Poole(FP) emission that higher dry-etching damage in the sidewall leads to the higher tunneling current, while below pinch-off voltage, the leakage is only related to the AlGaN surface, which is independent of RF power. 展开更多
关键词 AlGaN/GaN Schottky barrier diodes recessed anode etching damage TUNNELING
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A low on-resistance SOI LDMOS using a trench gate and a recessed drain 被引量:2
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作者 葛锐 罗小蓉 +6 位作者 蒋永恒 周坤 王沛 王琦 王元刚 张波 李肇基 《Journal of Semiconductors》 EI CAS CSCD 2012年第7期43-46,共4页
An integrable silicon-on-insulator (SOl) power lateral MOSFET with a trench gate and a recessed drain (TGRD MOSFET) is proposed to reduce the on-resistance. Both of the trench gate extended to the buried oxide (... An integrable silicon-on-insulator (SOl) power lateral MOSFET with a trench gate and a recessed drain (TGRD MOSFET) is proposed to reduce the on-resistance. Both of the trench gate extended to the buried oxide (BOX) and the recessed drain reduce the specific on-resistance (Ron, sp) by widening the vertical conduction area and shortening the extra current path. The trench gate is extended as a field plate improves the electric field distribution. Breakdown voltage (BV) of 97 V and Ron, sp of 0.985 mf2-cm2 (l/os = 5 V) are obtained for a TGRD MOSFET with 6.5/xm half-cell pitch. Compared with the trench gate SOI MOSFET (TG MOSFET) and the conventional MOSFET, Ron' sp of the TGRD MOSFET decreases by 46% and 83% at the same BV, respectively. Compared with the SOI MOSFET with a trench gate and a trench drain (TGTD MOSFET), BV of the TGRD MOSFET increases by 37% at the same Ron,sp. 展开更多
关键词 trench gate recessed drain ON-RESISTANCE breakdown voltage
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GaN metal-oxide-semiconductor field-effect transistors on AIGaN/GaN heterostructure with recessed gate
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作者 Qingpeng WANG Jin-Ping AO +4 位作者 Pangpang WANG Ying JIANG Liuan LI Kazuya KAWAHARADA Yang LIU 《Frontiers of Materials Science》 SCIE CSCD 2015年第2期151-155,共5页
GaN metal-oxide-semiconductor field-effect transistors (MOSFETs) on AIGaN/GaN heterostructure with a recess gate were fabricated and characterized. The device showed good pinch-off characteristics and a maximum fiel... GaN metal-oxide-semiconductor field-effect transistors (MOSFETs) on AIGaN/GaN heterostructure with a recess gate were fabricated and characterized. The device showed good pinch-off characteristics and a maximum field-effect mobility of 145.2 cm2.V-1.s-1. The effects of etching gas of CI2 and SiCI4 were investigated in the gate recess process. SiCI4-etched devices showed higher channel mobility and lower threshold voltage. Atomic force microscope measurement was done to investigate the etching profile with different etching protection mask. Compared with photoresist, SiO2- masked sample showed lower surface roughness and better profile with stepper sidewall and weaker trenching effect resulting in higher channel mobility in the MOSFET. 展开更多
关键词 gallium nitride MOSFET recess gate dry etching
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PIC-integrable,uniformly tensile-strained Ge-on-insulator photodiodes enabled by recessed SiN_(x) stressor
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作者 YIDING LIN DANHAO MA +5 位作者 KWANG HONG LEE RUI-TAO WEN GOVINDO SYARANAMUAL LIONEL CKIMERLING CHUAN SENG TAN JURGEN MICHEL 《Photonics Research》 SCIE EI CAS CSCD 2021年第7期1255-1263,共9页
Mechanical strain engineering has been promising for many integrated photonic applications. However,for the engineering of a material electronic bandgap,a trade-off exists between the strain uniformity and the integra... Mechanical strain engineering has been promising for many integrated photonic applications. However,for the engineering of a material electronic bandgap,a trade-off exists between the strain uniformity and the integration compatibility with photonic-integrated circuits (PICs). Herein,we adopted a straightforward recess-type design of a silicon nitride (SiNx) stressor to achieve a uniform strain with enhanced magnitude in the material of interest on PICs. Normal-incidence,uniformly 0.56% tensile strained germanium (Ge)-on-insulator (GOI) metal-semiconductor-metal photodiodes were demonstrated,using the recessed stressor with 750 MPa tensile stress. The device exhibits a responsivity of 1.840.15 A∕W at 1550 nm. The extracted Ge absorption coefficient is enhanced by -3.2×to 8340 cm^(-1) at 1612 nm and is superior to that of In_(0.53)Ga_(0.47)As up to 1630 nm limited by the measurement spectrum. Compared with the nonrecess strained device,additional absorption coefficient improvement of 10%–20% in the C-band and 40%–60% in the L-band was observed. This work facilitates the recessstrained GOI photodiodes for free-space PIC applications and paves the way for various (e.g.,Ge,GeSn or III-V based) uniformly strained photonic devices on PICs. 展开更多
关键词 RECESS STRAINED stress
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Novel approach of ultrasound-guided lateral recess block for a patient with lateral recess stenosis: A case report 被引量:1
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作者 Jiao Yang Xin-Ling Li Qing-Bing Li 《World Journal of Clinical Cases》 SCIE 2024年第5期1010-1017,共8页
BACKGROUND Ultrasound guide technology,which can provide real-time visualization of the needle tip and tissues and avoid many adverse events,is widely used in mini-mally invasive therapy.However,the studies on ultraso... BACKGROUND Ultrasound guide technology,which can provide real-time visualization of the needle tip and tissues and avoid many adverse events,is widely used in mini-mally invasive therapy.However,the studies on ultrasound-guided Lateral recess block(LRB)are limited,this is probably because there is no recognized standard method for ultrasound scanning.This study aimed to evaluate the effect of ultrasound-guided LRB in patients with lateral recess stenosis(LRS).CASE SUMMARY A 65-year-old patient complained of low back pain accompanied occasionally by pain and numbness in the left lower limb.Physical examination showed ten-derness on the spinous process and paraspinal muscles from L1 to S1,extensor hallucis longus and tibialis anterior weakness(muscle strength:4-),and a positive straight leg raising test in the left lower limb(60°).Magnetic resonance imaging showed L4–L5 disc degeneration with left LRS and nerve root entrapment.Subsequently,the patient was diagnosed with LRS.This patient was treated with a novel ultrasound-guided LRB approach.The patient’s symptoms significantly improved without any complications at 1 wk postoperatively and at the 3-month follow-up.CONCLUSION This is the first report on the LRS treatment with ultrasound-guided LRB from the contralateral spinous process along the inner side of the articular process by out-plane technique.Further studies are expected to investigate the efficacy and safety of ultrasound-guided LRB for patients with LRS. 展开更多
关键词 Lateral recess stenosis ULTRASOUND Lateral recess block Real-time visualization Low back pain Case report
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Comprehensive analysis of glacier recession(2000-2020)in the Nun-Kun Group of Glaciers,Northwestern Himalaya
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作者 Shakil Ahmad ROMSHOO Ummer AMEEN +1 位作者 Mustafa Hameed BHAT Tariq ABDULLAH 《Journal of Mountain Science》 SCIE CSCD 2024年第3期768-785,共18页
Himalayan glaciers are shrinking rapidly,especially after 2000.Glacier shrinkage,however,shows a differential pattern in space and time,emphasizing the need to monitor and assess glacier changes at a larger scale.In t... Himalayan glaciers are shrinking rapidly,especially after 2000.Glacier shrinkage,however,shows a differential pattern in space and time,emphasizing the need to monitor and assess glacier changes at a larger scale.In this study,changes of 48 glaciers situated around the twin peaks of the Nun and Kun mountains in the northwestern Himalaya,hereafter referred to as Nun-Kun Group of Glaciers(NKGG),were investigated using Landsat satellite data during 2000-2020.Changes in glacier area,snout position,Equilibrium Line Altitude(ELA),surface thickness and glacier velocity were assessed using remote sensing data supplemented by field observations.The study revealed that the NKGG glaciers have experienced a recession of 4.5%±3.4%and their snouts have retreated at the rate of 6.4±1.6 m·a^(-1).Additionally,there was a 41%increase observed in the debris cover area during the observation period.Using the geodetic approach,an average glacier elevation change of-1.4±0.4 m·a^(-1)was observed between 2000 and 2012.The observed mass loss of the NKGG has resulted in the deceleration of glacier velocity from 27.0±3.7 m·a^(-1)in 2000 to 21.2±2.2 m·a^(-1)in 2020.The ELA has shifted upwards by 83.0±22 m during the period.Glacier morphological and topographic factors showed a strong influence on glacier recession.Furthermore,a higher recession of 12.9%±3.2%was observed in small glaciers,compared to 2.7%±3.1%in larger glaciers.The debris-covered glaciers showed lower shrinkage(2.8%±1.1%)compared to the clean glaciers(9.3%±5%).The glacier depletion recorded in the NKGG during the last two decades,if continued,would severely diminish glacial volume and capacity to store water,thus jeopardizing the sustainability of water resources in the basin. 展开更多
关键词 Nun-Kun range Glacier recession Glacier snout Remote Sensing HIMALAYA Glacier velocity
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Identifying flow regime in the aquifer of fractured rock system in Germi Chai Basin,Iran
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作者 VAEZIHIR Abdorreza SEPEHRIPOUR Ali TABARMAYEH Mehri 《Journal of Mountain Science》 SCIE CSCD 2024年第2期574-589,共16页
Considering the importance of fractured rock aquifers in the hydrogeologic process,this research aimed to analyze the flow regime,internal degree of karstification,and estimate storage volume in fractured rock aquifer... Considering the importance of fractured rock aquifers in the hydrogeologic process,this research aimed to analyze the flow regime,internal degree of karstification,and estimate storage volume in fractured rock aquifers of the Germi Chai Basin in northwest Iran,which is attributed to its active tectonics,erosion,and the lithological diversity.Given the geological setting,the hypothesis is that this basin is characterized by a high degree of karstification and diffuse or intermediate flow regime leading to variation in discharge flow rate.The hydrodynamic and hadrochemical analysis was conducted on 9 well distributed springs across the basin from 2019 to 2020.The maximum flow rate in most of the springs appeared in the early wet season despite their different levels of fluctuations on the monthly discharge time series.Analyzing the spring recession curve form revealed an aquifer containing multiple micro-regimes withαrecession coefficients and a degree of karstification ranging between 0.001 to 0.06 and 0.55 to 2.61,respectively.These findings indicated a dominant diffuse and intermediate flow system resulting from the development of a high density of fractures in this area.The electrical conductivity of the spring changes inversely proportional to the change in flow discharge,indicating the reasonable hydrological response of the aquifer to rainfall events.Hydrograph analysis revealed that the delay time of spring discharge after rainfall events mostly varies between 10 to 30 days.The total dynamic storage volume of the spring for a given period(2019-2020)was estimated to be approximately 1324 million cubic meters reflecting the long-term drainage potential and high perdurability of dynamic storage.Estimating the maximum and minimum ratio revealed that the springs recharging system in Germi Chai Basin comes under the slow aquifers category.This finding provides valuable insight into the hydrogeological properties of fractured rock aquifers contributing to effective water management strategy. 展开更多
关键词 Fractured rock aquifer Hydrodynamic and hadrochemical analysis Germi Chai Basin Recession coefficient
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Detection of Novel BEST1 Variations in Autosomal Recessive Bestrophinopathy Using Third-generation Sequencing
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作者 Jia-xun LI Ling-rui MENG +6 位作者 Bao-ke HOU Xiao-lu HAO Da-jiang WANG Ling-hui QU Zhao-hui LI Lei ZHANG Xin JIN 《Current Medical Science》 SCIE CAS 2024年第2期419-425,共7页
Objective:Autosomal recessive bestrophinopathy(ARB),a retinal degenerative disease,is characterized by central visual loss,yellowish multifocal diffuse subretinal deposits,and a dramatic decrease in the light peak on ... Objective:Autosomal recessive bestrophinopathy(ARB),a retinal degenerative disease,is characterized by central visual loss,yellowish multifocal diffuse subretinal deposits,and a dramatic decrease in the light peak on electrooculogram.The potential pathogenic mechanism involves mutations in the BEST1 gene,which encodes Ca2+-activated Cl−channels in the retinal pigment epithelium(RPE),resulting in degeneration of RPE and photoreceptor.In this study,the complete clinical characteristics of two Chinese ARB families were summarized.Methods:Pacific Biosciences(PacBio)single-molecule real-time(SMRT)sequencing was performed on the probands to screen for disease-causing gene mutations,and Sanger sequencing was applied to validate variants in the patients and their family members.Results:Two novel mutations,c.202T>C(chr11:61722628,p.Y68H)and c.867+97G>A,in the BEST1 gene were identified in the two Chinese ARB families.The novel missense mutation BEST1 c.202T>C(p.Y68H)resulted in the substitution of tyrosine with histidine in the N-terminal region of transmembrane domain 2 of bestrophin-1.Another novel variant,BEST1 c.867+97G>A(chr11:61725867),located in intron 7,might be considered a regulatory variant that changes allele-specific binding affinity based on motifs of important transcriptional regulators.Conclusion:Our findings represent the first use of third-generation sequencing(TGS)to identify novel BEST1 mutations in patients with ARB,indicating that TGS can be a more accurate and efficient tool for identifying mutations in specific genes.The novel variants identified further broaden the mutation spectrum of BEST1 in the Chinese population. 展开更多
关键词 autosomal recessive bestrophinopathy BEST1 gene third-generation sequencing MUTATION
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New recessive compound heterozygous variants of RP1L1 in RP1L1 maculopathy
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作者 Wen-Chao Cao Qing-Shan Chen +2 位作者 Run Gan Tao Huang Xiao-He Yan 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第1期107-112,共6页
AIM:To identify a maculopathy patient caused by new recessive compound heterozygous variants in RP1L1.METHODS:Comprehensive retinal morphological and functional examinations were evaluated for the patient with RP1L1 m... AIM:To identify a maculopathy patient caused by new recessive compound heterozygous variants in RP1L1.METHODS:Comprehensive retinal morphological and functional examinations were evaluated for the patient with RP1L1 maculopathy.Targeted sequence capture array technique was used to screen potential pathologic variants.Polymerase chain reaction and Sanger sequencing were used to confirm the screening results.RESULTS:Fundus examination showed round macular lesions appeared in both eyes.Optical coherence tomography showed that the inner segment/outer segment continuity was disorganized and disruptive in the left eye,but it was uneven and slightly elevated in the right eye.Fundus autofluorescence showed patchy hyper-autofluorescence in the macula.Visual field examination indicates central defects in both eyes.Electroretinogram(ERG)and multifocal ERG showed no obvious abnormalities.Fundus fluorescein angiography in the macula showed obviously irregular hyper-fluorescence in the right eye and slightly hyper-fluorescence in the left eye.We found that the proband carried a missense variant(c.1972C>T)and a deletion variant(c.4717_4718del)of RP1L1,which were originated from the parents and formed compound heterozygous variants.Both variants are likely pathogenic according to the ACMG criteria.Multimodal imaging,ERG and detailed medical history are important diagnostic tools for differentiating between acquired and inherited retinal disorders.CONCLUSION:A maculopathy case with detailed retinal phenotype and new recessive compound heterozygous variants of RP1L1 is identified in a Chinese family,which expands the understanding of phenotype and genotype in RP1L1 maculopathy. 展开更多
关键词 MACULOPATHY RECESSIVE compound heterozygous variants RP1L1
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3M syndrome patient with a novel mutation:A case rep
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作者 Ming-Ran Luo Si-Ming Dai +7 位作者 Yin Li Qian Wang Hao Liu Peng Gao Jia-Yun Liu Jian Chen Shu-Jie Zhao Guo-Yong Yin 《World Journal of Clinical Cases》 SCIE 2024年第8期1454-1460,共7页
BACKGROUND A rare autosomal recessive genetic disorder,3M syndrome,is characterized by severe intrauterine and postnatal growth retardation.Children with 3M syndrome typically exhibit short stature,facial deformities,... BACKGROUND A rare autosomal recessive genetic disorder,3M syndrome,is characterized by severe intrauterine and postnatal growth retardation.Children with 3M syndrome typically exhibit short stature,facial deformities,long tubular bones,and high vertebral bodies but generally lack mental abnormalities or other organ damage.Pathogenic genes associated with 3M syndrome include CUL7,OBSL1 and CCDC8.The clinical and molecular characteristics of patient with 3M syn-drome are unique and serve as important diagnostic indicators.CASE SUMMARY In this case,the patient displayed square shoulders,scoliosis,long slender tubular bones,and normal neurological development.Notably,the patient did not exhibit the typical dysmorphic facial features,relative macrocephaly,or growth retardation commonly observed in individuals with 3M syndrome.Whole exon sequencing revealed a novel heterozygous c.56681+1G>C(Splice-3)variant and a previously reported nonsense heterozygous c.3341G>A(p.Trp1114Ter)variant of OBSL1.Therefore,it is important to note that the clinical features of 3M syndrome may not always be observable,and genetic confirmation is often required.Additionally,the identification of the c.5683+1G>C variant in OBSL1 is notewor-thy because it has not been previously reported in public databases.CONCLUSION Our study identified a new variant(c.5683+1G>C)of OBSL1 that contributes to expanding the molecular profile of 3M syndrome. 展开更多
关键词 3M syndrome CUL7 OBSL1 CCDC8 Autosomal recessive Case report
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Factors that influence the results of indirect decompression employing oblique lumbar interbody fusion
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作者 Andrey E Bokov Svetlana Y Kalinina +2 位作者 Mingiyan I Khaltyrov Alexandr P Saifullin Anatoliy A Bulkin 《World Journal of Orthopedics》 2024年第8期734-743,共10页
BACKGROUND Indirect decompression is one of the potential benefits of anterior reconstruction in patients with spinal stenosis.On the other hand,the reported rate of revision surgery after indirect decompression highl... BACKGROUND Indirect decompression is one of the potential benefits of anterior reconstruction in patients with spinal stenosis.On the other hand,the reported rate of revision surgery after indirect decompression highlights the necessity of working out prediction models for the radiographic results of indirect decompression with assessing their clinical relevance.AIM To assess factors that influence radiographic and clinical results of the indirect decompression in patients with stenosis of the lumbar spine.METHODS This study is a single-center cross-sectional evaluation of 80 consecutive patients(17 males and 63 females)with lumbar spinal stenosis combined with the instability of the lumbar spinal segment.Patients underwent single level or bisegmental spinal instrumentation employing oblique lumbar interbody fusion(OLIF)with percutaneous pedicle screw fixation.Radiographic results of the indirect decompression were assessed using computerized tomography,while MacNab scale was used to assess clinical results.RESULTS After indirect decompression employing anterior reconstruction using OLIF,the statistically significant increase in the disc space height,vertebral canal square,right and left lateral canal depth were detected(Р<0.0001).The median(M)relative vertebral canal square increase came toМ=24.5%with 25%-75%quartile border(16.3%;33.3%)if indirect decompression was achieved by restoration of the segment height.In patients with the reduction of the upper vertebrae slip,the median of the relative increase in vertebral canal square accounted for 49.5%with 25%-75%quartile border(2.35;99.75).Six out of 80 patients(7.5%)presented with unsatisfactory results because of residual nerve root compression.The critical values for lateral recess depth and vertebral canal square that were associated with indirect decompression failure were 3 mm and 80 mm2 respectively.CONCLUSION Indirect decompression employing anterior reconstruction is achieved by the increase in disc height along the posterior boarder and reduction of the slipped vertebrae in patients with degenerative spondylolisthesis.Vertebral canal square below 80 mm2 and lateral recess depth less than 3 mm are associated with indirect decompression failures that require direct microsurgical decompression. 展开更多
关键词 Indirect decompression Anterior reconstruction Central lumbar spinal stenosis Degenerative spondylolisthesis Lateral recess stenosis Spinal instability Oblique lateral interbody fusion
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Methylmalonic Acidemia: An Unusual Cause of Chronic Renal Disease in Adults
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作者 Kamel El Reshaid Abdulrahman Al Kanderi 《Open Journal of Nephrology》 2024年第3期334-339,共6页
Background: Methylmalonic aciduria (MMA) is a genetic disorder of aminoacid metabolism, due to mutations in methylmalonyl-CoA mutase, which leads to the accumulation of methylmalonic acid in body fluids. Patients typi... Background: Methylmalonic aciduria (MMA) is a genetic disorder of aminoacid metabolism, due to mutations in methylmalonyl-CoA mutase, which leads to the accumulation of methylmalonic acid in body fluids. Patients typically present at the age of 1 month to 1 year with dehydration, renal impairment as well as neurologic manifestations viz. seizure, encephalopathy, strokes and disease in the globus pallidi. The case: a 26-year-old man presented with severe acute on top of chronic renal disease with serum creatinine at 590 umol/L and bilateral 8 cm kidneys with thin and echogenic cortex. He had: (a) hypernatremic dehydration, metabolic acidosis and high ammonia level with (b) a history of multiple similar attacks since the age of 8 months. Diagnosis of MMA was confirmed by high serum and urine enzymatic levels as well as genetic testing. His initial management included support with replacements of fluids, electrolytes, and bicarbonates as well as intravenous dextrose, vitamin B12 and broad-spectrum antibiotic (Meropenem) for his chest infection. Subsequently, he received 1) CARBAGLU (carglumic acid) for 7 days to lower his ammonia level to Conclusion: Untreated homozygous MMA variants, can achieve adulthood with significant renal disease yet their morbidity and mortality can be ameliorated with diet and specific therapy. 展开更多
关键词 Methylmalonic Acidemia Kidney Failure Metabolic Acidosis Autosomal Recessive Amino Acid Disorder Kreps Cycle Hyperammonia Vitamin 12 CARNITINE
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Searching Development-deficient Genes in Edible Mushroom by Self-crossing 被引量:4
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作者 柴红梅 周会明 +2 位作者 赵静 陈卫民 赵永昌 《Agricultural Science & Technology》 CAS 2012年第10期2037-2043,共7页
[Objective] This study aimed to investigate the effect of mating factor recombination on the development of edible mushroom,and explore the possibility for using self-crossing to breed sporeless/low sporing mushroom s... [Objective] This study aimed to investigate the effect of mating factor recombination on the development of edible mushroom,and explore the possibility for using self-crossing to breed sporeless/low sporing mushroom strains.[Method] Selecting Agrocybe salicacola strain YAASM0711 as the self-crossing material,six self-crossed combinations were directionally constructed with single spore growth rate as an indicator,to carry out comprehensive analysis of the qualitative traits(color,deformity and growth characteristics),quantitative traits(shape,yield,size and number of fruit bodies) and mating types of its self-crossed F1 progenies.[Result] After mating factor recombination,self-crossed single spore progenies showed serious genetic differentiation,the average mycelial growth rate and agronomic traits of inbred progenies were lower than those of the parents.The phenotype in fruiting body formation could be divided into normal fruiting and abnormal fruiting(including abnormal fruiting bodies,sporeless or low sporing fruiting bodies,no fruiting).To be specific,18% self-crossed strains had superior agronomic traits to the parents,which can be used for selecting predominant strains from self-crossed progeny populations based on different breeding purposes.[Conclusion] The genes controlling mycelial growth rate of single spore were linked with mating factors.The mating factor-recombinant single spore strains could be selected according to the correlation between mating type and growth rate.The fruiting result of self-crossed strains indicated that the genes related to sporeless/low sporing development were recessive.Not only genetic materials harboring development-deficient genes in edible mushroom can be obtained by self-crossing,but also the sporeless/low sporing mutant strains with important application prospects can be bred. 展开更多
关键词 Agrocybe salicacola Self-crossing Fruiting identification Sporeless Recessive gene
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Molecular Markers and Agronomic Traits of a New Kind of Genic Male Sterile Material Mian 7AB-4-2 in Brassica napus L. 被引量:1
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作者 李浩杰 汤天泽 +4 位作者 袁代斌 蒙大庆 蒲晓斌 张锦芳 蒋梁材 《Agricultural Science & Technology》 CAS 2009年第1期60-63,152,共5页
[ Objective] The study was to investigate the agronomic traits and breeding characteristics of genic male sterile material Mian 7AB-4- 2 in Brassica napus. [ Method] The differences in agronomic traits and polymorphis... [ Objective] The study was to investigate the agronomic traits and breeding characteristics of genic male sterile material Mian 7AB-4- 2 in Brassica napus. [ Method] The differences in agronomic traits and polymorphisms in SSR markers, between the genic male sterile material Mian 7AB-4-2 in Brassica napus and its sisterly line Mian 7AB-4-1 were investigated by hybridization and molecular identification; and the percentage of sterile individuals of Mian 7AB-4-2 and of the hybrids with its sisterly line Mian 7AB-4-1 from test cross and back cross were also studled. [ Result] Mian 7AB-4-2 was not significantly different in agronomic traits from its sisterly line Mian 7AB-4-1 at 0.05 probability level. The per- centages of sterile individuals in the pollinated fertile Mian 7AB-4-2 plants were over 60%, and that in its sisterly line Mian 7AB-4-1 was about 25%. In test crosses with other nine sterile lines, Mian 7AB-4-1 kept the percentage of sterile individuals of sterile lines over 90%, and the percentage of sterile individuals from back cross over 80%. With regard to molecular markers, Mian 7AB-4-2 and its sisterly line Mian 7AB-4-1 were different in the band number from SSR primers a2 and E10. [ Conclusion] The results indicate that Mian 7AB-4-2 is helpful for rapeseed breeding, quickening the application of new materials in field breeding. 展开更多
关键词 Brassica napus L. Recessive genic male sterility Self-pollination of fertile individual Test cross Back cross SSR marker POLYMORPHISM
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100-nm T-gate InAlAs/InGaAs InP-based HEMTs with f_T = 249 GHz and f_(max) = 415 GHz 被引量:2
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作者 汪丽丹 丁芃 +3 位作者 苏永波 陈娇 张毕禅 金智 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第3期613-618,共6页
InA1As/InGaAs high electron mobility transistors (HEMTs) on an InP substrate with well-balanced cutoff frequency fT and maximum oscillation frequency frnax are reported. An InA1As/InGaAs HEMT with 100-nm gate length... InA1As/InGaAs high electron mobility transistors (HEMTs) on an InP substrate with well-balanced cutoff frequency fT and maximum oscillation frequency frnax are reported. An InA1As/InGaAs HEMT with 100-nm gate length and gate width of 2 × 50 μm shows excellent DC characteristics, including full channel current of 724 mA/mm, extrinsic maximum transconductance gm.max of 1051 mS/mm, and drain-gate breakdown voltage BVDG of 5.92 V. In addition, this device exhibits fT = 249 GHz and fmax = 415 GHz. These results were obtained by fabricating an asymmetrically recessed gate and minimizing the parasitic resistances. The specific Ohmic contact resistance was reduced to 0.031 0.mm. Moreover, the fT obtained in this work is the highest ever reported in 100-nm gate length InA1As/InGaAs InP-based HEMTs. The outstanding gm.max, fT, fmax, and good BVDG make the device suitable for applications in low noise amplifiers, power amplifiers, and high speed circuits. 展开更多
关键词 InP high electron mobility transistor asymmetrically recessed gate cutoff frequency fx maximumoscillation frequency fmax
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Primary Study on Reasons for the Growth Re-cession of Fragrant Camphor Trees at the West Lake Scenic Area and Diagnosis Procedure 被引量:1
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作者 肖昆仑 《Agricultural Science & Technology》 CAS 2013年第3期470-474,共5页
Fragrant camphor tree is the city tree of Hangzhou which takes a large proportion of the ancient trees in Hangzhou City. Recently, with the free open of the attractions around the West Lake and the implementation of t... Fragrant camphor tree is the city tree of Hangzhou which takes a large proportion of the ancient trees in Hangzhou City. Recently, with the free open of the attractions around the West Lake and the implementation of the comprehensive pro- ject for protecting the West Lake, a part of ancient fragrant camphor trees are fac- ing problems such as altered living conditons. Some of them are showing a decline in growth vigor or even close to death, which will produce extremely negative influ- ences on the maintaining and sustainable development of the West Lake Scenic Area if without any timely measures for the rescue and rejuvenation of the trees. Therefore, strengthening the protection and management of ancient fragrant camphor trees at the West Lake Scenic Area and carrying out researches on the procedure for diagnosing the reasons for the growth recession of the ancient fragrant camphor trees at the West Lake Scenic Area are of great significance for the future protec- tion and rejuvenation of the ancient trees around the West Lake. The factors influ- encing the growth of ancient trees and indexes for judging the growth condition were listed and the reasons for the growth recession were systematically summa- rized in this paper. In addition, measures for the rejuvenation of the ancient fragrant camphor trees were also simply discussed. 展开更多
关键词 The West Lake Scenic Area Fragrant camphor tree Growth and recession REJUVENATION
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Square Logistic Model for the Appearance of Lethal Recessive Homozygous Genotype in Random Mating Population
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作者 韦文惠 王子平 +2 位作者 林建国 蔡润 李大林 《Agricultural Science & Technology》 CAS 2008年第3期1-5,共5页
From the random mating population of maize, the relationship between heterosis and albino seedling was analyzed by means of mathematical theory, further the square logistic model for the appearance of lethal recessive... From the random mating population of maize, the relationship between heterosis and albino seedling was analyzed by means of mathematical theory, further the square logistic model for the appearance of lethal recessive homozygous genotype was deduced. The model shows that heterosis can determine the genetic structure and proportion of population. It approves, that the proportion of aa in each generation of maize seedlings shows a similar Logistic curve in growth process till equilibrium, so long as Aa containins lethal gene a from mutation presents heterosis. The ratio of equilibrium state of aa is determined by the ratio of AA-Aa fitness. Heterosis is helpful for the keeping of genetic diversity of population. 展开更多
关键词 Fitness RECESSIVE LETHAL HETEROSIS Random MATING Equilibrium
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Drug Sensitive Test on Main Pathogenic Bacteria of Cow Recessiveness Mastitis Using Traditional Chinese Medicine Preparation “Zengrujianniusan”
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作者 高桂生 安继伟 +5 位作者 胡铁锋 高光平 史秋梅 张艳英 邵新华 梁银聚 《Agricultural Science & Technology》 CAS 2017年第2期277-279,共3页
According to the theory of Chinese veterinary medicine and characteristics of Chinese herbal medicine, four different preparations of compound Chinese medicine "Zengrujianniusan" were composed, and the prepared wate... According to the theory of Chinese veterinary medicine and characteristics of Chinese herbal medicine, four different preparations of compound Chinese medicine "Zengrujianniusan" were composed, and the prepared water decoction was used to carry on the bacteriostatic test on main pathogens of cow recessiveness mastitis. The results showed that the four different prescriptions of water decoction all had antibacterial effects. The prescription 3 was sensitive to Staphylococcus aureus and Streptococcus agalactiae, while the other three prescriptions showed high sensitivity, and the prescription 3 had the strongest bacteriostatic effects. 展开更多
关键词 Traditional Chinese medicine preparation Cow recessiveness mastitis Pathogenic bacteria Bacteriostatic effect
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