Hospitalized prevalence and 5-year mortality for IBD:Record linkage study

AIM:To establish the hospitalized prevalence of severe Crohn's disease(CD) and ulcerative colitis(UC) in Wales from 1999 to 2007;and to investigate long-term mortality after hospitalization and associations with social deprivation and other socio-demographic factors.METHODS:Record linkage of administrative inpatient and mortality data for 1467 and 1482 people hospitalised as emergencies for ≥ 3d for CD and UC,respectively.The main outcome measures were hospitalized prevalence,mortality rates and standardized mortality ratios for up to 5 years follow-up after hospitalization.RESULTS:Hospitalized prevalence was 50.1 per 100 000 population for CD and 50.6 for UC.The hospitalized prevalence of CD was significantly higher(P < 0.05) in females(57.4) than in males(42.2),and was highest in people aged 16-29 years,but the prevalence of UC was similar in males(51.0) and females(50.1),and increased continuously with age.The hospital-ized prevalence of CD was slightly higher in the most deprived areas,but there was no association between social deprivation and hospitalized prevalence of UC.Mortality was 6.8% and 14.6% after 1 and 5 years follow-up for CD,and 9.2% and 20.8% after 1 and 5 years for UC.For both CD and UC,there was little discernible association between mortality and social deprivation,distance from hospital,urban/rural residence and geography.CONCLUSION:CD and UC have distinct demographic profiles.The higher prevalence of hospitalized CD in more deprived areas may reflect higher prevalence and higher hospital dependency.

An Automatic Threshold Selection Using ALO for Healthcare Duplicate Record Detection with Reciprocal Neuro-Fuzzy Inference System

ESystems based on EHRs(Electronic health records)have been in use for many years and their amplified realizations have been felt recently.They still have been pioneering collections of massive volumes of health data.Duplicate detections involve discovering records referring to the same practical components,indicating tasks,which are generally dependent on several input parameters that experts yield.Record linkage specifies the issue of finding identical records across various data sources.The similarity existing between two records is characterized based on domain-based similarity functions over different features.De-duplication of one dataset or the linkage of multiple data sets has become a highly significant operation in the data processing stages of different data mining programmes.The objective is to match all the records associated with the same entity.Various measures have been in use for representing the quality and complexity about data linkage algorithms,and many other novel metrics have been introduced.An outline of the problem existing in themeasurement of data linkage and de-duplication quality and complexity is presented.This article focuses on the reprocessing of health data that is horizontally divided among data custodians,with the purpose of custodians giving similar features to sets of patients.The first step in this technique is about an automatic selection of training examples with superior quality from the compared record pairs and the second step involves training the reciprocal neuro-fuzzy inference system(RANFIS)classifier.Using the Optimal Threshold classifier,it is presumed that there is information about the original match status for all compared record pairs(i.e.,Ant Lion Optimization),and therefore an optimal threshold can be computed based on the respective RANFIS.Febrl,Clinical Decision(CD),and Cork Open Research Archive(CORA)data repository help analyze the proposed method with evaluated benchmarks with current techniques.

Hash-Indexing Block-Based Deduplication Algorithm for Reducing Storage in the Cloud

Cloud storage is essential for managing user data to store and retrieve from the distributed data centre.The storage service is distributed as pay a service for accessing the size to collect the data.Due to the massive amount of data stored in the data centre containing similar information and file structures remaining in multi-copy,duplication leads to increase storage space.The potential deduplication system doesn’t make efficient data reduction because of inaccuracy in finding similar data analysis.It creates a complex nature to increase the storage consumption under cost.To resolve this problem,this paper proposes an efficient storage reduction called Hash-Indexing Block-based Deduplication(HIBD)based on Segmented Bind Linkage(SBL)Methods for reducing storage in a cloud environment.Initially,preprocessing is done using the sparse augmentation technique.Further,the preprocessed files are segmented into blocks to make Hash-Index.The block of the contents is compared with other files through Semantic Content Source Deduplication(SCSD),which identifies the similar content presence between the file.Based on the content presence count,the Distance Vector Weightage Correlation(DVWC)estimates the document similarity weight,and related files are grouped into a cluster.Finally,the segmented bind linkage compares the document to find duplicate content in the cluster using similarity weight based on the coefficient match case.This implementation helps identify the data redundancy efficiently and reduces the service cost in distributed cloud storage.

Perinatal and early life risk factors for inflammatory bowel disease

AIM:To investigate associations between perinatal risk factors and subsequent inflammatory bowel disease (IBD) in children and young adults.METHODS:Record linked abstracts of birth registrations,maternity,day case and inpatient admissions in a defined population of southern England.Investigation of 20 perinatal factors relating to the maternity or the birth:maternal age,Crohn's disease (CD) or ulcerative colitis (UC) in the mother,maternal social class,marital status,smoking in pregnancy,ABO blood group and rhesus status,pre-eclampsia,parity,the infant's presentation at birth,caesarean delivery,forceps delivery,sex,number of babies delivered,gestational age,birthweight,head circumference,breastfeeding and Apgar scores at one and five minutes.RESULTS:Maternity records were present for 180 children who subsequently developed IBD.Univariate analysis showed increased risks of CD among children of mothers with CD (P=0.011,based on two cases of CD in both mother and child) and children of mothers who smoked during pregnancy.Multivariate analysis confirmed increased risks of CD among children of mothers who smoked (odds ratio=2.04,95% CI=1.06-3.92) and for older mothers aged 35+ years (4.81,2.32-9.98).Multivariate analysis showed that there were no significant associations between CD and 17 other perinatal risk factors investigated.It also showed that,for UC,there were no significant associations with the perinatal factors studied.CONCLUSION:This study shows an association between CD in mother and child;and elevated risks of CD in children of older mothers and of mothers who smoked.

Linking temporal records

Many data sets contain temporal records which span a long period of time; each record is associated with a time stamp and describes some aspects of a real-world en- tity at a particular time （e.g., author information in DBLP）. In such cases, we often wish to identify records that describe the same entity over time and so be able to perform interest- ing longitudinal data analysis. However, existing record link- age techniques ignore temporal information and fall short for temporal data. This article studies linking temporal records. First, we ap- ply time decay to capture the effect of elapsed time on entity value evolution. Second, instead of comparing each pair of records locally, we propose clustering methods that consider the time order of the records and make global decisions. Ex- perimental results show that our algorithms significantly out- perform traditional linkage methods on various temporal data sets.