目的:研究64排螺旋X射线计算机体层扫描(CT)机低管电压联合高管电流技术用于肾癌术前诊断的价值。方法:选取医院收治的156例肾癌患者,采用随机数表法将其分为观察组和对照组,每组78例,两组均行全腹部多期增强CT扫描,观察组扫描参数中管...目的:研究64排螺旋X射线计算机体层扫描(CT)机低管电压联合高管电流技术用于肾癌术前诊断的价值。方法:选取医院收治的156例肾癌患者,采用随机数表法将其分为观察组和对照组,每组78例,两组均行全腹部多期增强CT扫描,观察组扫描参数中管电压为90 k V,管电流为550 m A;对照组管电压为120 k V,自动选择管电流。两组对比剂均为碘普罗胺,注射速度均为3.0 ml/s,对比剂剂量分别为1.0 ml/kg、1.5 ml/kg。采集两组皮髓质期(CMP)图像和实质期(NP)图像,记录并计算CMP图像的肿瘤感兴趣区域(ROI)、肾实质ROI、对比度噪声比(CNR)和信噪比(SNR)以及NP图像的肿瘤ROI、肾实质ROI、肾静脉ROI和SNR。采用4分法对两组采集的CMP、NP图像进行评分;对比两组CMP、NP的剂量长度乘积(DLP)和有效剂量(ED)的辐射剂量和总辐射剂量。结果:两组CMP和NP图像质量及主观评分差异均无统计学意义(P>0.05)。观察组CMP、NP的DLP和ED的辐射剂量以及总辐射剂量均低于对照组,其差异有统计学意义(t_(CMP)=5.086,t=9.833;t_(NP)=6.483,t=10.802;t_(总辐射剂量)=10.984;P<0.05)。结论:64排螺旋CT机低管电压联合高管电流技术进行肾癌诊断可清晰显示肾癌患者病灶,同时可降低对比剂使用剂量和辐射剂量,有利于减轻辐射对肾功能的损害。展开更多
The present study aimed to investigate the possibility of using dual-energy computed tomography (CT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without...The present study aimed to investigate the possibility of using dual-energy computed tomography (CT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without the need to use a contrast medium. The following patient data were extracted by interview and from the hospital’s radiology information system: height, weight, age, menstrual cycle, CT images of normal tissue and tumors with or without contrast medium, and the histopathological diagnosis of the aspiration biopsy. The median age of the 43 participants was 56 years (range, 30 - 80 years). The CT values were evaluated using a clinical analytical program based on the three-material decomposition technique. Breast cancer was classified into ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, fibromatosis-like metaplastic carcinoma, and apocrine carcinoma. In all conditions, regardless of contrast medium, the CT values of tumor tissues were higher than those of normal breast tissue, indicating the effectiveness of dual-energy CT (DE-CT) in the diagnosis of breast cancer. By contrast, DE-CT showed limited potential for distinguishing ductal carcinoma in situ from invasive ductal carcinoma. There have only been a few reports regarding CT examination of breast cancer, and it is expected this study encourage the development of DE-CT imaging to improve tumor detection in patients with breast cancer.展开更多
文摘目的:研究64排螺旋X射线计算机体层扫描(CT)机低管电压联合高管电流技术用于肾癌术前诊断的价值。方法:选取医院收治的156例肾癌患者,采用随机数表法将其分为观察组和对照组,每组78例,两组均行全腹部多期增强CT扫描,观察组扫描参数中管电压为90 k V,管电流为550 m A;对照组管电压为120 k V,自动选择管电流。两组对比剂均为碘普罗胺,注射速度均为3.0 ml/s,对比剂剂量分别为1.0 ml/kg、1.5 ml/kg。采集两组皮髓质期(CMP)图像和实质期(NP)图像,记录并计算CMP图像的肿瘤感兴趣区域(ROI)、肾实质ROI、对比度噪声比(CNR)和信噪比(SNR)以及NP图像的肿瘤ROI、肾实质ROI、肾静脉ROI和SNR。采用4分法对两组采集的CMP、NP图像进行评分;对比两组CMP、NP的剂量长度乘积(DLP)和有效剂量(ED)的辐射剂量和总辐射剂量。结果:两组CMP和NP图像质量及主观评分差异均无统计学意义(P>0.05)。观察组CMP、NP的DLP和ED的辐射剂量以及总辐射剂量均低于对照组,其差异有统计学意义(t_(CMP)=5.086,t=9.833;t_(NP)=6.483,t=10.802;t_(总辐射剂量)=10.984;P<0.05)。结论:64排螺旋CT机低管电压联合高管电流技术进行肾癌诊断可清晰显示肾癌患者病灶,同时可降低对比剂使用剂量和辐射剂量,有利于减轻辐射对肾功能的损害。
文摘The present study aimed to investigate the possibility of using dual-energy computed tomography (CT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without the need to use a contrast medium. The following patient data were extracted by interview and from the hospital’s radiology information system: height, weight, age, menstrual cycle, CT images of normal tissue and tumors with or without contrast medium, and the histopathological diagnosis of the aspiration biopsy. The median age of the 43 participants was 56 years (range, 30 - 80 years). The CT values were evaluated using a clinical analytical program based on the three-material decomposition technique. Breast cancer was classified into ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, fibromatosis-like metaplastic carcinoma, and apocrine carcinoma. In all conditions, regardless of contrast medium, the CT values of tumor tissues were higher than those of normal breast tissue, indicating the effectiveness of dual-energy CT (DE-CT) in the diagnosis of breast cancer. By contrast, DE-CT showed limited potential for distinguishing ductal carcinoma in situ from invasive ductal carcinoma. There have only been a few reports regarding CT examination of breast cancer, and it is expected this study encourage the development of DE-CT imaging to improve tumor detection in patients with breast cancer.
