Herein,we report a practical electro-reductive protocol for the direct C-H cyanoalkylation of quinoxalin-2(1 H)-ones via iminyl radical-mediated ring opening.These mild reactions proceed under metal-,reductant-,and re...Herein,we report a practical electro-reductive protocol for the direct C-H cyanoalkylation of quinoxalin-2(1 H)-ones via iminyl radical-mediated ring opening.These mild reactions proceed under metal-,reductant-,and reagent-free conditions to provide synthetically useful cyanoalkylated quinoxalin-2(1 H)-ones.展开更多
基金the National Natural Science Foundation of China(Nos.21732002,22077071)Frontiers Science Center for New Organic Matter,Nankai University(No.63181206)for generous financial support for our programs。
文摘Herein,we report a practical electro-reductive protocol for the direct C-H cyanoalkylation of quinoxalin-2(1 H)-ones via iminyl radical-mediated ring opening.These mild reactions proceed under metal-,reductant-,and reagent-free conditions to provide synthetically useful cyanoalkylated quinoxalin-2(1 H)-ones.
