A combined approach of target,suspected target and non-target screening using liquid chromatography-high-resolution mass spectrometry(LC-HRMS)was used to develop a new concept for water monitoring.With the current LC-...A combined approach of target,suspected target and non-target screening using liquid chromatography-high-resolution mass spectrometry(LC-HRMS)was used to develop a new concept for water monitoring.With the current LC-MS/MS target approach for water monitoring,all targets can be quantified,but no additional information about the sample is collected.With the new concept,it is possible to detect 97%of the target compounds with a simplified quantification method without losing accuracy.Furthermore,a suspect target screening can be performed to get broader qualitative information about the water samples.In addition,the non-target screening offers the possibility to identify unknown micropollutants.All three evaluation steps depend on the same analytical measurement so that a lot of measurement and quality assurance effort can be saved.This concept could change water monitoring and assessment,and make it much more efficiently without losing information.There is a chance to measure less but learn more about the water bodies.展开更多
文摘A combined approach of target,suspected target and non-target screening using liquid chromatography-high-resolution mass spectrometry(LC-HRMS)was used to develop a new concept for water monitoring.With the current LC-MS/MS target approach for water monitoring,all targets can be quantified,but no additional information about the sample is collected.With the new concept,it is possible to detect 97%of the target compounds with a simplified quantification method without losing accuracy.Furthermore,a suspect target screening can be performed to get broader qualitative information about the water samples.In addition,the non-target screening offers the possibility to identify unknown micropollutants.All three evaluation steps depend on the same analytical measurement so that a lot of measurement and quality assurance effort can be saved.This concept could change water monitoring and assessment,and make it much more efficiently without losing information.There is a chance to measure less but learn more about the water bodies.
